Roles > ultraviolet filter
Page last updated: 2024-08-05 15:24:13

ultraviolet filter

A photochemical role realized in the absorption of ultraviolet light, for example to protect skin cells from damage.

ChEBI ID: 73335

Members (5)

MemberDefinitionClass
esculetinA hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.esculetin
glyceryl ferulateAn enoate ester obtained by formal condensation of the carboxy group of trans-ferulic acid with the 1-hydroxy group of glycerol.1-feruloyl-sn-glycerol
oxybenzoneA hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively.oxybenzone
phenyl salicylateA benzoate ester that is the phenyl ester of salicylic acid. Also known as salol, it can be formed by heating salicylic acid with phenol and is used in the manufacture of some polymers, lacquers, adhesives, waxes and polishes.phenyl salicylate
scytoneminA ring assembly obtained by 1,1'-coupling of two molecules of (3E)-3-[(4-hydroxyphenyl)methylidene]cyclopenta[b]indol-2(3H)-one. A UV-screening molecule produced by many strains of cyanobacteria.scytonemin

Research

Studies (943)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199058 (6.15)18.7374
1990's91 (9.65)18.2507
2000's199 (21.10)29.6817
2010's403 (42.74)24.3611
2020's192 (20.36)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials15 (1.49%)5.53%
Reviews42 (4.17%)6.00%
Case Studies31 (3.08%)4.05%
Observational1 (0.10%)0.25%
Other919 (91.17%)84.16%

Protein Targets (121)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency17.915417
15-lipoxygenase, partialHomo sapiens (human)Potency12.924412
activating transcription factor 6Homo sapiens (human)Potency0.173811
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency29.383716
alpha-galactosidaseHomo sapiens (human)Potency27.852526
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency17.782811
AR proteinHomo sapiens (human)Potency26.3045615
aryl hydrocarbon receptorHomo sapiens (human)Potency35.076026
ATAD5 protein, partialHomo sapiens (human)Potency17.358222
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency79.432811
caspase-1 isoform alpha precursorHomo sapiens (human)Potency7.506012
Caspase-7Homo sapiens (human)Potency5.962212
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency23.675613
Chain A, Ferritin light chainEquus caballus (horse)Potency23.350712
Chain A, HADH2 proteinHomo sapiens (human)Potency20.480124
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency4.466811
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency13.538313
Chain B, HADH2 proteinHomo sapiens (human)Potency20.480124
chromobox protein homolog 1Homo sapiens (human)Potency89.125111
cytochrome P450 2C19 precursorHomo sapiens (human)Potency0.398111
cytochrome P450 2C9, partialHomo sapiens (human)Potency38.901811
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency12.589311
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency12.589323
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency26.282014
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency79.432811
DNA polymerase kappa isoform 1Homo sapiens (human)Potency7.355013
estrogen nuclear receptor alphaHomo sapiens (human)Potency29.46281125
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency26.7762614
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency79.432811
GVesicular stomatitis virusPotency38.901811
GABA theta subunitRattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency12.589312
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency12.589312
gemininHomo sapiens (human)Potency14.900422
GLI family zinc finger 3Homo sapiens (human)Potency29.013424
GLS proteinHomo sapiens (human)Potency35.481311
glucocerebrosidaseHomo sapiens (human)Potency28.183811
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency5.768212
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency26.925012
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency35.481311
Guanine nucleotide-binding protein GHomo sapiens (human)Potency1.000011
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)Homo sapiens (human)Potency50.118711
heat shock protein beta-1Homo sapiens (human)Potency43.820122
histone deacetylase 9 isoform 3Homo sapiens (human)Potency33.945929
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency38.901811
huntingtin isoform 2Homo sapiens (human)Potency11.220211
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency10.000022
IDH1Homo sapiens (human)Potency29.092911
importin subunit beta-1 isoform 1Homo sapiens (human)Potency62.303222
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency38.901812
Interferon betaHomo sapiens (human)Potency38.901811
lamin isoform A-delta10Homo sapiens (human)Potency23.350712
lethal factor (plasmid)Bacillus anthracis str. A2012Potency22.106012
LuciferasePhotinus pyralis (common eastern firefly)Potency25.855138
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency25.757433
Microtubule-associated protein tauHomo sapiens (human)Potency22.387211
mitogen-activated protein kinase 1Homo sapiens (human)Potency31.622811
muscleblind-like protein 1 isoform 1Homo sapiens (human)Potency25.118911
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency35.481311
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)Potency35.481311
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency51.788123
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency54.941011
Nuclear receptor ROR-gammaHomo sapiens (human)Potency37.578011
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency31.082939
P53Homo sapiens (human)Potency35.481311
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency11.882311
phosphopantetheinyl transferaseBacillus subtilisPotency45.857712
plasminogen precursorMus musculus (house mouse)Potency5.011911
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency36.906313
pregnane X nuclear receptorHomo sapiens (human)Potency48.579725
progesterone receptorHomo sapiens (human)Potency56.076513
RAR-related orphan receptor gammaMus musculus (house mouse)Potency15.749626
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency28.2203316
retinoid X nuclear receptor alphaHomo sapiens (human)Potency36.535724
SMAD family member 2Homo sapiens (human)Potency27.539111
SMAD family member 3Homo sapiens (human)Potency27.539111
Smad3Homo sapiens (human)Potency3.981111
snurportin-1Homo sapiens (human)Potency62.303222
survival motor neuron protein isoform dHomo sapiens (human)Potency11.220211
TAR DNA-binding protein 43Homo sapiens (human)Potency3.548111
TDP1 proteinHomo sapiens (human)Potency26.930625
thioredoxin reductaseRattus norvegicus (Norway rat)Potency67.833422
thyroid stimulating hormone receptorHomo sapiens (human)Potency30.345834
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency5.011911
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency5.011911
USP1 protein, partialHomo sapiens (human)Potency63.095711
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency26.925012

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Aldo-keto reductase family 1 member B1Homo sapiens (human)IC5067.200011
Beta-secretase 1Homo sapiens (human)IC50500.000011
Carbonic anhydrase 1Homo sapiens (human)Ki10.000011
Carbonic anhydrase 12Homo sapiens (human)Ki0.009311
Carbonic anhydrase 2Homo sapiens (human)Ki10.000011
Carbonic anhydrase 9Homo sapiens (human)Ki0.036411
Hormone-sensitive lipaseRattus norvegicus (Norway rat)IC503.250011
Induced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)IC508.770011
Induced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)Ki1.490011
large T antigenBetapolyomavirus macacaeIC5025.940011
M1-family alanyl aminopeptidasePlasmodium falciparum 3D7IC5048.200011
M17 leucyl aminopeptidasePlasmodium falciparum 3D7IC5035.300011
M18 aspartyl aminopeptidasePlasmodium falciparum 3D7IC5044.190011
Macrophage migration inhibitory factorHomo sapiens (human)IC50211.000011
Macrophage migration inhibitory factorHomo sapiens (human)Ki184.000011
MPI proteinHomo sapiens (human)IC5050.000022
Prostaglandin G/H synthase 1Homo sapiens (human)IC5057.000011
Serine/threonine-protein kinase PLK1Homo sapiens (human)IC502.000011
Sorbitol dehydrogenaseHomo sapiens (human)IC5082.900011
Xanthine dehydrogenase/oxidaseHomo sapiens (human)IC508.200011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
ERAP1 proteinHomo sapiens (human)AC509.720011
ERAP2 proteinHomo sapiens (human)AbsAC200_uM3.270011
leucyl-cystinyl aminopeptidase [Mus musculus]Mus musculus (house mouse)AbsAC200_uM2.120011