Page last updated: 2024-08-05 15:10:40

coccidiostat

An agent useful in the treatment or prevention of coccidiosis in man or animals.

ChEBI ID: 35818

Members (6)

MemberDefinitionClass
amproliumA pyridinium ion that is the cationic portion of amprolium, a veterinary drug which is used for prevention of coccidiosis in poultry and cattle.amprolium(1+)
lasalocidA polyether antibiotic used for prevention and treatment of coccidiosis in poultry.lasalocid
lasalocid sodiumThe sodium salt of lasalocid. It is a veterinary ionophore antibiotic used for prevention and treatment of coccidiosis in poultry.lasalocid sodium
monensinA spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle.monensin A
roxarsoneAn organoarsonic acid where the organyl group is 4-hydroxy-3-nitrophenyl.roxarsone
sulfadiazineA sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.sulfadiazine

Research

Studies (7,075)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19903,644 (51.51)18.7374
1990's1,411 (19.94)18.2507
2000's844 (11.93)29.6817
2010's799 (11.29)24.3611
2020's377 (5.33)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials285 (3.72%)5.53%
Reviews222 (2.90%)6.00%
Case Studies372 (4.86%)4.05%
Observational4 (0.05%)0.25%
Other6,771 (88.46%)84.16%

Protein Targets (69)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
67.9K proteinVaccinia virusPotency11.620823
Alpha-synucleinHomo sapiens (human)Potency35.481311
AR proteinHomo sapiens (human)Potency8.239679
ATAD5 protein, partialHomo sapiens (human)Potency25.918511
Ataxin-2Homo sapiens (human)Potency29.849311
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency10.691011
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency25.490522
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency79.432811
Cellular tumor antigen p53Homo sapiens (human)Potency25.677022
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency39.810711
Chain A, Beta-lactamaseEscherichia coli K-12Potency1.258911
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency89.125111
chromobox protein homolog 1Homo sapiens (human)Potency89.125111
cytochrome P450 2C19 precursorHomo sapiens (human)Potency10.000011
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency23.918511
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency3.349111
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)Potency1.258911
DNA polymerase betaHomo sapiens (human)Potency22.387211
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency22.874112
DNA polymerase kappa isoform 1Homo sapiens (human)Potency39.810711
estrogen nuclear receptor alphaHomo sapiens (human)Potency12.432356
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency54.754144
gemininHomo sapiens (human)Potency12.717625
glp-1 receptor, partialHomo sapiens (human)Potency8.971612
GLS proteinHomo sapiens (human)Potency11.220211
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency14.580633
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency16.165412
IDH1Homo sapiens (human)Potency15.364412
lamin isoform A-delta10Homo sapiens (human)Potency0.266312
lethal(3)malignant brain tumor-like protein 1 isoform IHomo sapiens (human)Potency35.481311
Microtubule-associated protein tauHomo sapiens (human)Potency17.782811
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency12.589311
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency5.173511
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency18.966222
nuclear receptor subfamily 1, group I, member 2Rattus norvegicus (Norway rat)Potency12.589311
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency7.943311
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency6.911111
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency14.125411
pregnane X nuclear receptorHomo sapiens (human)Potency34.804122
Rap guanine nucleotide exchange factor 3Homo sapiens (human)Potency63.095711
RAR-related orphan receptor gammaMus musculus (house mouse)Potency8.412711
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency24.163411
retinoid X nuclear receptor alphaHomo sapiens (human)Potency45.981022
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency29.934911
Smad3Homo sapiens (human)Potency10.000011
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency17.782811
TAR DNA-binding protein 43Homo sapiens (human)Potency22.387211
TDP1 proteinHomo sapiens (human)Potency3.917025
thioredoxin glutathione reductaseSchistosoma mansoniPotency31.622811
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency9.990923
thyroid stimulating hormone receptorHomo sapiens (human)Potency15.848922
transcriptional regulator ERG isoform 3Homo sapiens (human)Potency11.220211
TSHR proteinHomo sapiens (human)Potency4.775511
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency1.258911

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
14 kDa phosphohistidine phosphataseHomo sapiens (human)IC5080.000011
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000011
Aurora kinase AHomo sapiens (human)IC5021.000011
Bile salt export pumpHomo sapiens (human)IC50653.600035
Canalicular multispecific organic anion transporter 1Homo sapiens (human)IC50133.000011
Carbonic anhydrase 1Homo sapiens (human)IC5012.720313
Carbonic anhydrase 2Homo sapiens (human)IC5012.720313
Carbonic anhydrase 6Homo sapiens (human)IC5012.720313
Multidrug resistance-associated protein 4Homo sapiens (human)IC50133.000011
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)IC500.478611
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)Ki0.260011
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)IC500.776211
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)Ki0.590011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
alternatively spliced Trp4Mus musculus (house mouse)EC505.956011
neurotensin receptor type 1Homo sapiens (human)EC5030.500011
Nuclear receptor subfamily 1 group I member 2Homo sapiens (human)EC5011.700022

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
PAX8Homo sapiens (human)AC503.520011