Page last updated: 2024-09-28

Frambesia

Synonyms(2)

Synonym
Frambesia Tropica
Frambesia

Research

Studies (148)

TimeframeStudies, This Condition (%)All Conditions %
pre-199087 (58.78)23.3326
1990's4 (2.70)12.5806
2000's8 (5.41)18.1394
2010's39 (26.35)28.8240
2020's10 (6.76)9.53
DrugIndicatedRelationship StrengthStudiesTrials
formaldehyde0low10
niacin0low10
acetarsol0low20
pentamidine0low10
procaine0low20
stearic acid0low20
triclosan0low20
prednisone0low10
penicillin g0low100
chloramphenicol0low70
benzathine0low50
streptomycin0low10
dihydrostreptomycin sulfate0low10
mercuric chloride0low10
trolamine salicylate0low30
cetylpyridinium chloride anhydrous0low10
nsc-1727550low20
glycidyl nitrate0low10
borneo0low20
tartaric acid0low10
zithromax0medium386
phenylephrine hydrochloride0low30
antimony0low10
aluminum0low20
bismuth0low50
arsenic0low50
gallium maltolate0low10
phosphatidylcholines0low20
stearates0low10
tetracycline0low20
chlortetracycline0low90
oxytetracycline, anhydrous0low90
salicylates0low10
bismuth salicylate0low10
exudates0low90

Protein Targets (457)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma7007
ATAD5 protein, partial1001
thioredoxin glutathione reductase3003
heat shock protein beta-15005
importin subunit beta-1 isoform 13003
DNA polymerase beta2002
eyes absent homolog 2 isoform a1001
snurportin-13003
DNA polymerase iota isoform a (long)5005
geminin9009
survival motor neuron protein isoform d2002
muscleblind-like protein 1 isoform 13003
lamin isoform A-delta105005
Bile salt export pump011011
14 kDa phosphohistidine phosphatase0101
ATP-dependent phosphofructokinase3003
Chain A, Histamine N-methyltransferase0101
Chain A, Histamine N-methyltransferase0101
Chain A, Histamine N-methyltransferase0101
Chain A, Histamine N-methyltransferase0101
Smad32002
cytochrome P450 family 3 subfamily A polypeptide 44004
cytochrome P450 2D64004
Spike glycoprotein0011
Replicase polyprotein 1ab0011
lysosomal alpha-glucosidase preproprotein4004
GTP-binding nuclear protein Ran isoform 11001
Transmembrane protease serine 20011
Amyloid-beta precursor protein0202
Procathepsin L0011
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0213
Cytochrome P450 2C80001
Cytochrome P450 2C9 0415
Nuclear receptor subfamily 4 group A member 20011
Cytochrome P450 2J20202
Spike glycoprotein3014
Angiotensin-converting enzyme 2 0011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
DNA polymerase kappa isoform 12002
pregnane X receptor2002
GLI family zinc finger 3110011
AR protein100010
estrogen receptor 2 (ER beta)5005
nuclear receptor subfamily 1, group I, member 35005
progesterone receptor5005
retinoic acid nuclear receptor alpha variant 19009
retinoid X nuclear receptor alpha7007
estrogen-related nuclear receptor alpha110011
farnesoid X nuclear receptor4004
pregnane X nuclear receptor7007
estrogen nuclear receptor alpha130013
peroxisome proliferator-activated receptor delta6006
peroxisome proliferator activated receptor gamma6006
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
aryl hydrocarbon receptor4004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a5005
thyroid stimulating hormone receptor5005
activating transcription factor 64004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
v-jun sarcoma virus 17 oncogene homolog (avian)7007
thyroid hormone receptor beta isoform 27007
nuclear factor erythroid 2-related factor 2 isoform 19009
Voltage-dependent calcium channel gamma-2 subunit3003
Cellular tumor antigen p536006
Glutamate receptor 23003
Chain A, Ferritin light chain2002
acetylcholinesterase3003
hypoxia-inducible factor 1 alpha subunit3003
SMAD family member 22002
USP1 protein, partial3003
SMAD family member 32002
TDP1 protein7007
Microtubule-associated protein tau3003
caspase 7, apoptosis-related cysteine protease3003
glucocorticoid receptor [Homo sapiens]7007
67.9K protein1001
caspase-33003
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
thyrotropin-releasing hormone receptor3003
vitamin D3 receptor isoform VDRA4004
mitogen-activated protein kinase 11001
nuclear receptor ROR-gamma isoform 12002
Caspase-20011
Inositol monophosphatase 11001
ATPase family AAA domain-containing protein 53003
Ataxin-23003
interleukin 82002
aldehyde dehydrogenase 1 family, member A16006
EWS/FLI fusion protein3003
G3003
streptokinase A precursor0044
lethal factor (plasmid)2002
Dihydroxyacetone phosphate acyltransferase0002
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40606
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 3003
30S ribosomal protein S60415
30S ribosomal protein S70415
50S ribosomal protein L150415
Cytochrome P450 3A40404
50S ribosomal protein L100415
50S ribosomal protein L110415
50S ribosomal protein L7/L120415
50S ribosomal protein L190415
50S ribosomal protein L10415
50S ribosomal protein L200415
50S ribosomal protein L270415
50S ribosomal protein L280415
50S ribosomal protein L290415
50S ribosomal protein L310415
50S ribosomal protein L31 type B0415
50S ribosomal protein L320415
50S ribosomal protein L330415
50S ribosomal protein L340415
50S ribosomal protein L350415
50S ribosomal protein L360415
30S ribosomal protein S100415
30S ribosomal protein S110415
30S ribosomal protein S120415
30S ribosomal protein S130415
30S ribosomal protein S160415
30S ribosomal protein S180415
30S ribosomal protein S190415
30S ribosomal protein S200415
30S ribosomal protein S20415
30S ribosomal protein S30415
30S ribosomal protein S40415
30S ribosomal protein S50415
30S ribosomal protein S80415
30S ribosomal protein S90415
50S ribosomal protein L130415
50S ribosomal protein L140415
50S ribosomal protein L160415
50S ribosomal protein L230415
30S ribosomal protein S150415
50S ribosomal protein L170415
50S ribosomal protein L210415
50S ribosomal protein L300415
50S ribosomal protein L60415
30S ribosomal protein S140415
30S ribosomal protein S170415
30S ribosomal protein S10415
50S ribosomal protein L180415
50S ribosomal protein L20415
50S ribosomal protein L30415
50S ribosomal protein L240415
50S ribosomal protein L40415
50S ribosomal protein L220415
50S ribosomal protein L50415
30S ribosomal protein S210415
50S ribosomal protein L250415
50S ribosomal protein L36 20415
Inositol hexakisphosphate kinase 13003
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial3003
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120202
Protein-arginine deiminase type-40606
Chain A, Beta-lactamase2002
Motilin receptor0011
acid sphingomyelinase1001
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK12002
Motilin receptor0112
Rap guanine nucleotide exchange factor 33003
Albumin0011
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB10202
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0202
Chitinase B0101
ATP-dependent translocase ABCB10202
Low molecular weight phosphotyrosine protein phosphatase0101
10 kDa heat shock protein, mitochondrial0202
Potassium voltage-gated channel subfamily H member 20303
Cytochrome P450 1B10101
Thiosulfate sulfurtransferase0101
Lanosterol 14-alpha demethylase0101
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Canalicular multispecific organic anion transporter 10505
Multidrug and toxin extrusion protein 10303
PPM1D protein3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
nonstructural protein 11001
bromodomain adjacent to zinc finger domain 2B3003
IDH14004
nuclear receptor subfamily 1, group I, member 22002
nuclear factor erythroid 2-related factor 2 isoform 22002
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor0415
Glycine receptor subunit alpha-10404
Androgen receptor0202
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Nuclear receptor subfamily 1 group I member 20011
Chain A, JmjC domain-containing histone demethylation protein 3A3003
glp-1 receptor, partial4004
Polyphenol oxidase 20101
Neuronal acetylcholine receptor subunit alpha-43003
Cholesteryl ester transfer protein0101
Neuronal acetylcholine receptor subunit beta-23003
D-amino-acid oxidase0101
Xanthine dehydrogenase/oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, 2-oxoglutarate Oxygenase2002
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
thioredoxin reductase3003
WRN1001
phosphopantetheinyl transferase1001
GLS protein2002
Valosin-containing protein0101
apical membrane antigen 1, AMA11001
regulator of G-protein signaling 41001
euchromatic histone-lysine N-methyltransferase 24004
Histone H2A.x4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
chromobox protein homolog 14004
thyroid hormone receptor beta isoform a3003
transcriptional regulator ERG isoform 31001
microphthalmia-associated transcription factor isoform 90101
flap endonuclease 11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
eukaryotic translation initiation factor 4E isoform 10101
histone acetyltransferase KAT2A isoform 12002
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Serum paraoxonase/arylesterase 10101
phosphoglycerate kinase1001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Solute carrier family 22 member 60101
Beta-lactamase0001
Solute carrier family 22 member 80102
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase0001
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0001
Kappa-type opioid receptor0001
Solute carrier family 15 member 10101
Beta-lactamase TEM0102
Guanine nucleotide-binding protein G1001
Beta-lactamase0001
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Metallo-beta-lactamase VIM-130001
Beta-lactamase 0001
Beta-lactamase 0001
Efflux transporter 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Beta-lactamase 0001
Class D beta-lactamase0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Beta-lactamase VIM-1 0001
Protein arginine N-methyltransferase 50101
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0101
5-hydroxytryptamine receptor 40202
Protein tyrosine phosphatase type IVA 30101
Solute carrier family 22 member 30101
Coagulation factor X0101
Plasminogen0101
Urokinase-type plasminogen activator0101
Protein S100-B0112
Glyceraldehyde-3-phosphate dehydrogenase0101
Protein S100-B0011
Cytochrome P450 1A20101
Trypsin-10101
Aldo-keto reductase family 1 member B10202
Acrosin0101
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Cytochrome P450 2D60101
Angiotensin-converting enzyme0202
Amiloride-sensitive amine oxidase [copper-containing]0101
Amine oxidase [flavin-containing] A0101
Diamine acetyltransferase 10101
Sodium-dependent noradrenaline transporter 0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Cytochrome P450 2C190101
D(3) dopamine receptor0202
Sodium-dependent dopamine transporter 0202
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Protein tyrosine phosphatase type IVA 20101
Nuclear receptor subfamily 3 group C member 3 0202
Multidrug and toxin extrusion protein 20101
Protein tyrosine phosphatase type IVA 10101
Aurora kinase B0101
Protein arginine N-methyltransferase 10101
Suppressor of tumorigenicity 14 protein0101
GALC protein1001
beta-2 adrenergic receptor1001
Bloom syndrome protein isoform 11001
mu-type opioid receptor isoform MOR-10011
Vpr2002
peripheral myelin protein 221001
5-hydroxytryptamine receptor 2A0011
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Nuclear receptor ROR-gamma2002
thyroid stimulating hormone receptor4004
cytochrome P450 2D6 isoform 11001
muscarinic acetylcholine receptor M11001
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Luciferase1001
Anthranilate phosphoribosyltransferase0101
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
15-lipoxygenase, partial1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
Acetylcholinesterase0202
Prostaglandin G/H synthase 1 0101
Fatty acid-binding protein, adipocyte0011
Tyrosine-protein phosphatase non-receptor type 10101
Prostaglandin G/H synthase 20101
Peroxisome proliferator-activated receptor alpha0011
Bile salt export pump0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0203
Chain A, Prostatic Acid Phosphatase0101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20102
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
Stromelysin-10101
Multidrug transporter MdfA0101
Alpha-1B adrenergic receptor0101
Neutrophil collagenase0101
Alpha-1D adrenergic receptor0101
Alpha-synuclein1102
Alpha-1A adrenergic receptor0101
Collagenase 30101
Cannabinoid receptor 10101
Integrase 0101
Solute carrier family 22 member 110001
Solute carrier family 22 member 70001
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, Repressor0011
Fumarate hydratase1001
PINK11001
polyprotein1001
Parkin1001
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
Caspase-71001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
caspase-31001
twin arginine protein translocation system - TatA protein0002
Transthyretin0112
Polyunsaturated fatty acid 5-lipoxygenase0101
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
Endoplasmic reticulum chaperone BiP0101
Carbonyl reductase [NADPH] 10202
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
TAR DNA-binding protein 432002
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI0202
Enoyl-acyl carrier reductase0101
Enoyl-acyl-carrier protein reductase 0202
Enoyl-ACP reductase II 0101
heat shock protein 90, putative0001
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
cytochrome P450 3A4 isoform 11001
Gamma-aminobutyric acid receptor subunit pi1001
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
GABA theta subunit1001
Gamma-aminobutyric acid receptor subunit epsilon1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]