| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 1.5954 | 2 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 8.0896 | 1 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 20.2756 | 1 | 6 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 6.2093 | 1 | 4 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 5.8048 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 22.3872 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 0.8341 | 9 | 11 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 0.4431 | 3 | 5 |
| arylsulfatase A | Homo sapiens (human) | Potency | 13.3754 | 1 | 3 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 5.8063 | 3 | 4 |
| Ataxin-2 | Homo sapiens (human) | Potency | 5.7518 | 2 | 3 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 9.1173 | 1 | 2 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 5.4728 | 1 | 2 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 5.8219 | 1 | 2 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 3.5786 | 1 | 2 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 22.5358 | 2 | 4 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 0.5520 | 3 | 5 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 5.0981 | 2 | 7 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 17.9008 | 1 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 5.6234 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 5.6234 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 31.8326 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 23.7358 | 2 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 46.9553 | 1 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 12.2366 | 1 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 19.9787 | 1 | 4 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 23.7358 | 2 | 2 |
| chaperonin-containing TCP-1 beta subunit homolog | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 13.8914 | 1 | 2 |
| ClpP | Bacillus subtilis | Potency | 28.1838 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 12.7585 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 1.1314 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 4.7724 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 13.4504 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 9.3430 | 2 | 8 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 4.7724 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.9750 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 0.3445 | 2 | 2 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 1.9621 | 1 | 2 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 11.1313 | 2 | 3 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 31.0386 | 2 | 5 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 13.0407 | 2 | 6 |
| endonuclease IV | Escherichia coli | Potency | 18.1696 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 1.1355 | 8 | 14 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 15.0115 | 2 | 3 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 3.7946 | 10 | 21 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 8.8608 | 1 | 6 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 14.8698 | 4 | 8 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 2.5876 | 4 | 5 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 11.6934 | 1 | 3 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 3.3473 | 1 | 3 |
| G | Vesicular stomatitis virus | Potency | 4.7724 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| GALC protein | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 9.3430 | 1 | 4 |
| geminin | Homo sapiens (human) | Potency | 4.5931 | 4 | 10 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 9.3969 | 2 | 4 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 1.5849 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 3.4360 | 2 | 2 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 1.2723 | 2 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 2.0345 | 1 | 2 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 1.9953 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 20.3796 | 1 | 5 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 9.7100 | 2 | 3 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 6.9324 | 2 | 13 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 0.7360 | 2 | 4 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 4.7724 | 1 | 1 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 61.6448 | 1 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 4.8357 | 2 | 6 |
| IDH1 | Homo sapiens (human) | Potency | 9.3614 | 1 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 34.8936 | 2 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 4.7724 | 1 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 3.4173 | 1 | 3 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 3.4173 | 1 | 3 |
| Interferon beta | Homo sapiens (human) | Potency | 4.7724 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 4.4064 | 2 | 6 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 4.4472 | 1 | 3 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 8.1601 | 4 | 6 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 41.9147 | 1 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 11.0108 | 1 | 6 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 16.0620 | 1 | 2 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 7.6434 | 2 | 3 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 6.3096 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 29.8911 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 30.7015 | 1 | 3 |
| Nrf2 | Homo sapiens (human) | Potency | 2.9093 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 3.7857 | 3 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 8.1972 | 2 | 8 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 1.8966 | 3 | 5 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 1.5843 | 1 | 2 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 63.3294 | 1 | 2 |
| Parkin | Homo sapiens (human) | Potency | 8.7915 | 2 | 3 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 11.3433 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 9.3233 | 2 | 2 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 17.0936 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 1.1884 | 2 | 3 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 3.4974 | 4 | 6 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 22.3872 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 43.9284 | 1 | 2 |
| PINK1 | Homo sapiens (human) | Potency | 1.6326 | 1 | 2 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 3.5481 | 1 | 2 |
| polyprotein | Zika virus | Potency | 3.3473 | 1 | 3 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 19.9846 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 0.4883 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 15.7788 | 1 | 2 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 2.5119 | 2 | 2 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 1.5843 | 2 | 4 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 0.0574 | 1 | 2 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 43.5121 | 1 | 4 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 20.6013 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 0.0566 | 3 | 6 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 9.8408 | 4 | 6 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 4.3991 | 3 | 6 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 1.4972 | 2 | 4 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 1.4972 | 2 | 4 |
| Smad3 | Homo sapiens (human) | Potency | 0.4467 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 34.8936 | 2 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 0.5209 | 2 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 15.5886 | 1 | 6 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 17.5307 | 2 | 14 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 10.9203 | 3 | 7 |
| Thrombopoietin | Homo sapiens (human) | Potency | 0.5500 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 0.3270 | 2 | 4 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 1.4125 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 0.7506 | 2 | 4 |
| TSHR protein | Homo sapiens (human) | Potency | 92.5374 | 2 | 3 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 3.5481 | 1 | 2 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 3.5481 | 1 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 44.8455 | 1 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 61.6448 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 5.8844 | 4 | 6 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 24.1682 | 5 | 7 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 2.0345 | 1 | 2 |
| WRN | Homo sapiens (human) | Potency | 35.0356 | 1 | 2 |