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beta-carbolines

Any pyridoindole containing a beta-carboline skeleton and their hydrogenated derivatives

ChEBI ID: 60834

Members (39)

MemberDefinitionRole
2-(2-methoxyethyl)-9-methyl-1-oxo-N-(thiophen-2-ylmethyl)-4-pyrido[3,4-b]indolecarboxamide2-(2-methoxyethyl)-9-methyl-1-oxo-N-(thiophen-2-ylmethyl)-4-pyrido[3,4-b]indolecarboxamide
2-(2-methoxyethyl)-9-methyl-4-[(4-methyl-1-piperidinyl)-oxomethyl]-1-pyrido[3,4-b]indolone2-(2-methoxyethyl)-9-methyl-4-[(4-methyl-1-piperidinyl)-oxomethyl]-1-pyrido[3,4-b]indolone
2-(2-methoxyethyl)-9-methyl-N-[3-(4-methyl-1-piperidinyl)propyl]-1-oxo-4-pyrido[3,4-b]indolecarboxamide2-(2-methoxyethyl)-9-methyl-N-[3-(4-methyl-1-piperidinyl)propyl]-1-oxo-4-pyrido[3,4-b]indolecarboxamide
2-cyclohexyl-9-methyl-1-oxo-N-[3-(2-oxo-1-pyrrolidinyl)propyl]-4-pyrido[3,4-b]indolecarboxamide2-cyclohexyl-9-methyl-1-oxo-N-[3-(2-oxo-1-pyrrolidinyl)propyl]-4-pyrido[3,4-b]indolecarboxamide
2-cyclopentyl-4-[1,4-dioxa-8-azaspiro[4.5]decan-8-yl(oxo)methyl]-9-methyl-1-pyrido[3,4-b]indolone2-cyclopentyl-4-[1,4-dioxa-8-azaspiro[4.5]decan-8-yl(oxo)methyl]-9-methyl-1-pyrido[3,4-b]indolone
2-methyltryptoline1,2,3,4-Tetrahydro-2-methyl-b-carboline
3-hydroxymethyl-beta-carboline9H-pyrido[3,4-b]indol-3-ylmethanol
4-[[9-methyl-2-(2-methylpropyl)-1-oxo-4-pyrido[3,4-b]indolyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester4-[[9-methyl-2-(2-methylpropyl)-1-oxo-4-pyrido[3,4-b]indolyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester
5-hydroxytryptoline6-Hydroxytetrahydro-beta-carboline
5,8-dichloro-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one5,8-dichloro-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one
6-methoxy-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one6-methoxy-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one
8-hydroxymanzamine aAn alkaloid that is manzamine A with a hydroxy substituent at position 8. Isolated from Pachypellina and Acanthostrongylophora, it exhibits inhibitory activity against Glycogen Synthase Kinase-3 (EC 2.7.11.26).8-hydroxymanzamine A
9-methyl-7-bromoeudistomin d9-Methyl-7-bromoeudistomin D
annomontineAn alkaloid that is beta-carboline substituted at position C-1 by a 2-aminopyrimidin-4-yl moiety. An antiparasitic agent found in Annona montana and Annona foteida.annomontine
beta-carboline-3-carboxylic acid ethyl ester9H-pyrido[3,4-b]indole-3-carboxylic acid ethyl ester
beta-carboline-3-carboxylic acid methyl ester9H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester
centbutindolebiriperone
evodiamineLSM-6483
fg 7142N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide
ko 143LSM-6260
LSM-16248LSM-16248
LSM-4272LSM-4272
manzamine aAn alkaloid of the class of beta-carbolines isolated from Haliclona and Acanthostrongylophora. It exhibits inhibitory activity against Glycogen Synthase Kinase-3 (EC 2.7.11.26).manzamine A
methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate4-ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester
Methyl nigakinoneMethyl nigakinone
metralindolemetralindole
n-butyl beta-carboline-3-carboxylateN-Butyl-beta-carboline-3-carboxylate
N-ethylharmineA member of the class of beta-carbolines that is 9H-beta-carboline substituted by a ethyl group at position 9, methoxy group at position 7 and a methyl group at position 1. It is semisynthetic derivative of harmine and has been shown to exhibit significant anti-HIV activity.N-ethylharmine
nigakinoneNigakinone
norharmanThe parent compound of the beta-carbolines, a tricyclic structure comprising an indole ring system ortho- fused to C-3 and C-4 of a pyridine ring.beta-carboline
nostocarbolineA member of the class of beta-carbolines that is 9H-beta-carbolin-2-ium substituted by a chloro group at position 6 and a methyl group at position 2. It is isolated from a fresh water cyanobacterium Nostoc 78-12A and acts as an inhibitor of butyrylcholinesterase.nostocarboline
propyl beta-carboline-3-carboxylate9H-pyrido[3,4-b]indole-3-carboxylic acid propyl ester
ps1145N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide
rutecarpineRutecarpine
strictosamideStrictosamide
tryptoline2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
tubulosineA member of the class of beta-carbolines that is tubulosan bearing methoxy groups at positions 10 and 11 and a hydroxy group at the 8' position.tubulosine
zk 934234-(methoxymethyl)-6-phenylmethoxy-9H-pyrido[3,4-b]indole-3-carboxylic acid ethyl ester
zk 934264-methyl-5-propan-2-yloxy-9H-pyrido[3,4-b]indole-3-carboxylic acid ethyl ester

Research

Studies (2,271)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990587 (25.85)18.7374
1990's433 (19.07)18.2507
2000's450 (19.82)29.6817
2010's589 (25.94)24.3611
2020's212 (9.34)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials15 (0.54%)5.53%
Reviews110 (3.96%)6.00%
Case Studies2 (0.07%)4.05%
Observational0 (0.00%)0.25%
Other2,648 (95.42%)84.16%