Ochronosis

The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).

Synonym
Ochronosis

Excerpt	Reference
"Exogenous ochronosis is caused by the long-term application of skin-lightening creams containing hydroquinone."	( Jordaan, HF; Van Niekerk, DJ, 1991)
"Ochronosis is a rare disease caused by an inherited lack of homogentisic acid oxidase."	( De Clerck, LS; Francx, LM; Stevens, WJ; Van Offel, JF, 1995)
"Ochronosis is the dark pigmentation of connective tissues in patients with alkaptonuria."	( Dom, K; Pittevils, T, 1997)
"Ochronosis is a musculoskeletal manifestation of alkaptonuria, a rare hereditary metabolic disorder characterised by the absence of the enzyme homogentisic acid oxidase and associated with various systemic abnormalities related to the deposition of homogentisic acid pigment (ochronotic pigment)."	( Aynaci, O; Onder, C; Turhan, AU, 2000)
"Exogenous ochronosis is clinically and histologically similar to its endogenous counterpart; however, it exhibits no systemic effects and is not an inherited disorder."	( Levin, CY; Maibach, H, 2001)
"Alkaptonuric ochronosis is rare disorder of tyrosin catabolism with an autosomal recessive trait."	( Cobos Soler, FJ; Molero Cabrilla, R, 2002)
"Ochronosis is a model of arthropathy with known etiologic factors."	( Airó, P; Andreotti, L; Cammelli, D; Giorgi, M; Lorenzini, S; Mannoni, A; Marcolongo, R; Porfirio, B; Selvi, E, 2004)
"Exogenous ochronosis is a cutaneous disorder characterized by blue-black or slate-gray hyperpigmentation resulting from the prolonged use of certain topical agents, most commonly hydroquinones."	( Alster, TS; Bellew, SG, 2004)
"Exogenous ochronosis is a paradoxical hyper-pigmentation of the skin caused by the long-term use of hydroquinone-containing bleaching creams."	( Aricò, M; Bongiorno, MR, 2005)
"Ochronosis is the pigmentation of connective tissues and this pigmentation leads to degenerative changes in alkaptonuric patients."	( Daneyemez, M; Gürkanlar, D; Solmaz, I; Temiz, C, 2006)
"Exogenous ochronosis is an avoidable dermatosis that is difficult to treat."	( Azulay-Abulafia, L; Barcaui, CB; Charlín, R; Kac, BK; Rabello-Fonseca, R; Soares, DB, 2008)
"Ochronosis is a rare disease."	( Bougaki, M; Kitamura, T; Ohno, N; Orii, R; Saito, Y; Yamada, Y, 2008)
"Ochronosis is a rare genetic metabolic disorder resulting from a constitutional lack of homogentisic acid oxidase and subsequent accumulation of its substrate causing destruction of connective tissues with various systemic abnormalities."	( Babic-Naglic, D; Curkovic, B; Laktasic-Zerjavic, N; Potocki, K; Prutki, M; Soldo-Juresa, D, 2010)
" Exogenous ochronosis is difficult to treat."	( Deshpande, DJ; Dhurat, RS; Mishra, SN; Nayak, CS, 2013)
"Ochronosis is the blue-gray discoloration of collagen-containing tissues due to homogentisic acid (HGA) deposition, secondary to endogenous alkaptonuria or exogenous enzyme inhibition."	( Hugar, SB; Nine, J; Shulman, J; Yanta, J, 2019)
"Ochronosis is the process in alkaptonuria (AKU) that causes all the debilitating morbidity."	( Gallagher, JA; Norman, BP; Ranganath, LR, 2019)

Excerpt	Reference
"Exogenous ochronosis has been reported following the topical use of phenol in leg ulcers, the topical use of hydroquinone bleaching creams in black persons, and the oral administration of antimalarials for malaria and connective tissue diseases, but we could find no reports in the literature of exogenous ochronosis following intramuscular injections of antimalarials."	( Bruce, S; Chow, D; Tschen, JA, 1986)
"Exogenous ochronosis has characteristic features on dermatoscopy which may obviate the need for an invasive procedure of biopsy for its diagnosis."	( Deshpande, DJ; Dhurat, RS; Mishra, SN; Nayak, CS, 2013)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	95 (37.40)	23.3326
1990's	20 (7.87)	12.5806
2000's	50 (19.69)	18.1394
2010's	60 (23.62)	28.8240
2020's	29 (11.42)	9.53

Drug	Relationship Strength	Studies	Trials
ammonium hydroxide	low	1	0
quinacrine	low	4	0
carbamates	low	1	0
hydrogen carbonate	low	1	0
homogentisic acid	low	92	0
hydroquinone	low	43	0
thioctic acid	low	1	0
phytic acid	low	1	0
phenol	low	2	0
taurine	low	1	0
uric acid	low	3	0
alendronate	medium	1	1
diclofenac	low	1	0
2-propanol	low	1	0
oxybenzone	low	1	0
quinone	low	1	0
phenacetin	low	1	0
resorcinol	low	3	0
prednisolone	low	2	0
penicillamine	low	1	0
methylprednisolone acetate	low	1	0
aspartic acid	low	1	0
cyanides	low	1	0
levodopa	low	2	0
tyrosine	low	18	0
phenylalanine	low	6	0
methandrostenolone	low	1	0
trichloroacetic acid	low	1	0
methylprednisolone	low	1	0
acetylcysteine	low	2	0
durapatite	low	2	0
mercury	low	2	0
silver	low	1	0
technetium	low	2	0
chromium	low	1	0
gold	low	1	0
tricalcium phosphate	low	1	0
fluorine	low	1	0
calcium pyrophosphate	low	5	0
trolamine salicylate	low	47	0
tiletamine hydrochloride	low	10	0
phenyl acetate	low	2	0
4-methoxyamphetamine	low	1	0
delphinidin	low	1	0
fluorodeoxyglucose f18	low	1	0
nitisinone	low	11	0
cortisone	low	3	0
glucosamine	low	2	0
tretinoin	low	1	0
ferulic acid	low	1	0
pyrophosphate	low	3	0
methylthiouracil	low	2	0
thiouracil	low	1	0
quinine	low	1	0
methenolone	low	1	0
beryllium	low	1	0
alpha-synuclein	low	1	0
atrial natriuretic factor	low	1	0
oligonucleotides	low	1	0
chondroitin	low	3	0
ascorbic acid	low	16	0
tetracycline	low	2	0
minocycline	low	1	0
allopurinol	low	1	0
alcian blue	low	1	0
eye	low	6	0

Protein Targets (740)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	6	0	0	6
RAR-related orphan receptor gamma	14	0	0	14
GLI family zinc finger 3	15	0	0	15
AR protein	20	0	0	20
aldehyde dehydrogenase 1 family, member A1	11	0	0	11
retinoic acid nuclear receptor alpha variant 1	15	0	0	15
retinoid X nuclear receptor alpha	13	0	0	13
estrogen nuclear receptor alpha	27	0	0	27
peroxisome proliferator-activated receptor delta	11	0	0	11
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	11	0	0	11
activating transcription factor 6	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
Histone H2A.x	4	0	0	4
thyroid hormone receptor beta isoform a	7	0	0	7
heat shock protein beta-1	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	18	0	0	18
lamin isoform A-delta10	11	0	0	11
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Glutamate receptor 2	10	0	0	10
5-hydroxytryptamine receptor 2C	0	1	1	2
5-hydroxytryptamine receptor 2A	0	1	1	2
5-hydroxytryptamine receptor 1A	0	6	3	10
5-hydroxytryptamine receptor 1B	0	3	1	4
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	1	1	2
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	2	1	3
Sodium-dependent serotonin transporter	0	1	0	1
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
acetylcholinesterase	5	0	0	5
dopamine D1 receptor	4	0	0	4
15-lipoxygenase, partial	3	0	0	3
pregnane X receptor	4	0	0	4
phosphopantetheinyl transferase	8	0	0	8
USP1 protein, partial	7	0	0	7
NFKB1 protein, partial	2	0	0	2
Microtubule-associated protein tau	5	0	0	5
Thrombopoietin	2	0	0	2
regulator of G-protein signaling 4	6	0	0	6
glucocorticoid receptor [Homo sapiens]	18	0	0	18
farnesoid X nuclear receptor	4	0	0	4
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
arylsulfatase A	8	0	0	8
euchromatic histone-lysine N-methyltransferase 2	15	0	0	15
Bloom syndrome protein isoform 1	9	0	0	9
D(1A) dopamine receptor	3	0	0	3
thyroid hormone receptor beta isoform 2	10	0	0	10
flap endonuclease 1	6	0	0	6
geminin	14	0	0	14
peripheral myelin protein 22	6	0	0	6
survival motor neuron protein isoform d	5	0	0	5
muscarinic acetylcholine receptor M1	4	0	0	4
Histone deacetylase 3	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Histone deacetylase 4	0	1	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Histone deacetylase 1	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Ataxin-2	9	0	0	9
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
ATP-dependent phosphofructokinase	7	0	0	7
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Acetylcholinesterase	0	5	0	5
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
interleukin 8	4	0	0	4
TDP1 protein	16	0	0	16
thyroid stimulating hormone receptor	3	0	0	3
estrogen receptor 2 (ER beta)	7	0	0	7
progesterone receptor	8	0	0	8
estrogen-related nuclear receptor alpha	14	0	0	14
IDH1	8	0	0	8
transcriptional regulator ERG isoform 3	1	0	0	1
ras-related protein Rab-9A	3	0	0	3
ATP-binding cassette sub-family C member 3	0	10	0	10
Multidrug resistance-associated protein 4	0	10	0	10
Polyphenol oxidase 2	0	5	0	11
Bile salt export pump	0	15	0	15
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Cellular tumor antigen p53	9	0	0	9
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	1	2	3
Xanthine dehydrogenase/oxidase	0	2	0	2
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	5	0	0	5
Canalicular multispecific organic anion transporter 1	0	9	0	9
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
chromobox protein homolog 1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
lethal factor (plasmid)	3	0	0	3
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	4	0	4
Alpha-2B adrenergic receptor	0	2	2	5
Spike glycoprotein	4	0	0	4
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	8	0	0	8
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	6	0	0	6
Chain A, Ferritin light chain	2	0	0	2
cytochrome P450 2C19 precursor	3	0	0	3
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	9	0	13
Carbonic anhydrase 2	0	10	0	14
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	4
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	4
Glutamate receptor ionotropic, NMDA 2B	0	1	0	4
Glutamate receptor ionotropic, NMDA 2C	0	1	0	4
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	1	0	4
Glutamate receptor ionotropic, NMDA 3B	0	1	0	4
Carbonic anhydrase 4	0	1	0	2
Glutamate receptor ionotropic, NMDA 3A	0	1	0	4
Atrial natriuretic peptide receptor 1	0	0	1	1
Atrial natriuretic peptide receptor 1	0	0	1	1
Chain A, HADH2 protein	6	0	0	6
Chain B, HADH2 protein	6	0	0	6
endonuclease IV	2	0	0	2
thioredoxin reductase	7	0	0	7
GLS protein	5	0	0	5
pregnane X nuclear receptor	13	0	0	13
peroxisome proliferator activated receptor gamma	10	0	0	10
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	2	0	0	2
peripheral myelin protein 22 isoform 1	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
cytochrome P450 3A4 isoform 1	4	0	0	4
M-phase phosphoprotein 8	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	4	3	2	9
Glucocorticoid receptor	0	6	1	12
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	6	0	6
Corticosteroid-binding globulin	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	4	3	2	9
Gamma-aminobutyric acid receptor subunit delta	4	3	2	9
Gamma-aminobutyric acid receptor subunit gamma-2	4	3	2	9
Gamma-aminobutyric acid receptor subunit alpha-5	4	3	2	9
Gamma-aminobutyric acid receptor subunit alpha-3	4	3	2	9
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-1	4	3	2	9
Gamma-aminobutyric acid receptor subunit alpha-2	4	3	2	9
Glycine receptor subunit alpha-3	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	4	3	2	9
Gamma-aminobutyric acid receptor subunit gamma-3	4	3	2	9
Gamma-aminobutyric acid receptor subunit alpha-6	4	3	2	9
Gamma-aminobutyric acid receptor subunit alpha-1	4	3	2	9
Gamma-aminobutyric acid receptor subunit beta-3	4	3	2	9
Gamma-aminobutyric acid receptor subunit beta-2	4	3	2	9
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
GABA theta subunit	4	3	2	9
Multidrug and toxin extrusion protein 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	4	3	2	9
Carbonic anhydrase 4	0	6	0	9
Carbonic anhydrase	0	3	0	6
Carbonic anhydrase 15	0	5	0	8
Epidermal growth factor receptor	0	2	0	2
Vascular endothelial growth factor receptor 2	0	1	0	1
Alpha-synuclein	0	4	0	4
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
Gamma-aminobutyric acid	0	1	0	1
glp-1 receptor, partial	2	0	0	2
nuclear receptor subfamily 1, group I, member 3	10	0	0	10
G	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Interferon beta	6	0	0	6
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
Fatty acid-binding protein, liver	0	3	0	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	1	5	7
Albumin	0	0	1	1
ATP-dependent translocase ABCB1	0	4	1	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	3	5
Translocator protein	0	1	1	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
Inositol hexakisphosphate kinase 1	5	0	0	5
ATPase family AAA domain-containing protein 5	6	0	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
cytochrome P450 2C9, partial	5	0	0	5
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Transthyretin	0	0	1	3
Prostaglandin G/H synthase 1	0	1	1	2
Cytochrome P450 3A4	0	2	1	3
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Cytochrome P450 2C9	0	5	1	7
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	2	0	3
UDP-glucuronosyltransferase 1-6	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Cytochrome P450 2J2	0	5	0	5
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 9	0	6	0	9
Solute carrier family 22 member 6	0	2	0	3
Prostaglandin G/H synthase 1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
ClpP	1	0	0	1
67.9K protein	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
Acetylcholinesterase	0	2	0	2
Carbonic anhydrase 12	0	4	0	7
Amyloid-beta precursor protein	0	2	0	2
Cholinesterase	0	3	0	3
Carbonic anhydrase 3	0	4	0	7
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Pyruvate kinase PKM	0	1	0	1
Carbonic anhydrase 6	0	5	0	8
Adenosine receptor A1	0	2	0	5
Adenosine receptor A2a	0	2	0	5
Carbonic anhydrase 5A, mitochondrial	0	5	0	8
Carbonic anhydrase 7	0	4	0	7
Alpha-glucosidase MAL12	0	1	0	1
Cholinesterase	0	2	0	2
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	1	0	1
Hyaluronidase-1	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Integrase	0	2	0	2
Carbonic anhydrase 13	0	4	0	6
Carbonic anhydrase 14	0	4	0	7
Carbonic anhydrase 5B, mitochondrial	0	4	0	7
DNA polymerase kappa isoform 1	7	0	0	7
Chain A, Penicillin Amidohydrolase	0	2	0	2
Chain B, Penicillin Amidohydrolase	0	2	0	2
Chain A, Penicillin Amidohydrolase	0	2	0	2
Chain B, Penicillin Amidohydrolase	0	2	0	2
Chain A, Penicillin Amidohydrolase	0	2	0	2
Chain B, Penicillin Amidohydrolase	0	2	0	2
Chain A, Penicillin Amidohydrolase	0	2	0	2
Chain B, Penicillin Amidohydrolase	0	2	0	2
Chain A, Penicillin Amidohydrolase	0	2	0	2
Chain B, Penicillin Amidohydrolase	0	2	0	2
Chain A, Penicillin Amidohydrolase	0	2	0	2
Chain B, Penicillin Amidohydrolase	0	2	0	2
Chain A, Penicillin Amidohydrolase	0	2	0	2
Chain B, Penicillin Amidohydrolase	0	2	0	2
Chain A, Carbonic anhydrase 2	0	2	0	2
Chain A, Carbonic anhydrase 2	0	2	0	2
Chain A, Carbonic anhydrase 2	0	2	0	2
Nrf2	1	0	0	1
ATAD5 protein, partial	3	0	0	3
DNA polymerase III, partial	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4	0	0	4
cytochrome P450 2D6	4	0	0	4
Parkin	2	0	0	2
aryl hydrocarbon receptor	8	0	0	8
thyroid stimulating hormone receptor	5	0	0	5
Caspase-7	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
hemoglobin subunit beta	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
caspase-3	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
nuclear receptor ROR-gamma isoform 1	5	0	0	5
Tyrosinase	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	2	0	2
Nuclear receptor ROR-gamma	5	1	1	7
Carbonic anhydrase	0	3	0	3
large T antigen	0	1	0	1
Luciferase	6	0	0	6
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
apical membrane antigen 1, AMA1	1	0	0	1
EWS/FLI fusion protein	5	0	0	5
pyruvate kinase	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
importin subunit beta-1 isoform 1	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
snurportin-1	2	0	0	2
DNA polymerase eta isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	3	0	0	3
Plasma kallikrein	0	0	0	3
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Carbonic anhydrase	0	0	0	3
Large neutral amino acids transporter small subunit 1	0	3	0	4
SLC16A10 protein	0	0	0	3
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
phosphoglycerate kinase	1	0	0	1
PPM1D protein	1	0	0	1
nonstructural protein 1	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
muscleblind-like protein 1 isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Androgen receptor	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Protein-arginine deiminase type-4	0	3	0	3
4-hydroxyphenylpyruvate dioxygenase	0	1	0	1
4-hydroxyphenylpyruvate dioxygenase	0	1	0	1
4-hydroxyphenylpyruvate dioxygenase	0	1	0	1
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
Smad3	2	0	0	2
P53	1	0	0	1
cytochrome P450 2D6 isoform 1	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
histone deacetylase 9 isoform 3	1	0	0	1
huntingtin isoform 2	1	0	0	1
mitogen-activated protein kinase 1	2	0	0	2
Hormone-sensitive lipase	0	1	0	1
vitamin D3 receptor isoform VDRA	3	0	0	3
Bile salt export pump	0	2	0	2
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
histone acetyltransferase KAT2A isoform 1	4	0	0	4
Cytochrome P450 1A2	0	0	0	2
Cytochrome P450 1A2	0	2	1	4
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
alpha-galactosidase	1	0	0	1
Endolysin	0	0	1	1
Sulfotransferase 1A1	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 3	0	3	0	3
Carbonic anhydrase 13	0	1	0	2
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, Beta-arrestin 1	0	0	1	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Beta-1 adrenergic receptor	0	1	1	3
Solute carrier family 22 member 1	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Beta-2 adrenergic receptor	0	2	1	3
Muscarinic acetylcholine receptor M2	0	4	1	5
Beta-1 adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 1A	0	1	0	1
Alpha-2A adrenergic receptor	0	3	2	6
Adenosine receptor A3	0	3	1	4
Beta-2 adrenergic receptor	0	2	0	3
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2D6	0	3	1	4
Muscarinic acetylcholine receptor M1	0	3	1	4
Beta-3 adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	4	1	5
Beta-1 adrenergic receptor	0	2	1	4
Alpha-2C adrenergic receptor	0	3	2	6
D(3) dopamine receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	1	1
Muscarinic acetylcholine receptor M3	0	3	1	4
D(1A) dopamine receptor	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Alpha-2C adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	0	1	1
Alpha-1D adrenergic receptor	0	3	1	4
Alpha-1D adrenergic receptor	0	2	1	4
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 2A	0	4	1	5
5-hydroxytryptamine receptor 2C	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
Cytochrome P450 2C19	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	2	4
Alpha-1B adrenergic receptor	0	0	1	2
Mu-type opioid receptor	0	1	1	2
Vasopressin V1a receptor	0	1	1	2
Delta-type opioid receptor	0	1	1	2
Kappa-type opioid receptor	0	1	1	2
5-hydroxytryptamine receptor 2B	0	4	1	5
Alpha-1A adrenergic receptor	0	4	1	5
5-hydroxytryptamine receptor 6	0	2	1	3
5-hydroxytryptamine receptor 7	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Beta-2 adrenergic receptor	0	1	1	3
Sigma non-opioid intracellular receptor 1	0	2	0	2
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
N	0	1	0	1
Fumarate hydratase	1	0	0	1
NPYLR7B	0	0	1	1
polyprotein	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
cystic fibrosis transmembrane conductance regulator	0	1	0	1
tumor susceptibility gene 101 protein	1	0	0	1
Glutathione reductase, mitochondrial	0	1	0	1
Riboflavin-binding protein	0	1	1	2
Major prion protein	0	0	1	1
Major prion protein	0	1	0	1
Histidine-rich protein PFHRP-II	0	2	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M5	0	2	0	2
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Histamine H2 receptor	0	2	0	2
Trypanothione reductase	0	2	0	2
D(3) dopamine receptor	0	2	0	2
D(1A) dopamine receptor	1	0	0	1
Aldehyde oxidase 1	0	1	0	1
Aldehyde oxidase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
Cytochrome P450 2D4	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
Dihydroorotate dehydrogenase	0	1	0	1
DNA polymerase beta	2	0	0	2
serine/threonine-protein kinase PLK1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	0	2	0	2
Cocaine esterase	0	1	0	1
Thymidylate synthase	0	0	0	1
Coagulation factor XII	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Glutamate receptor 1	2	0	0	2
Glutamate receptor 3	2	0	0	2
Glutamate receptor 4	2	0	0	2
Carbon monoxide dehydrogenase small chain	0	0	1	1
Amine oxidase [flavin-containing] A	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Dual specificity protein phosphatase 1	0	1	0	1
Caspase-1	0	1	0	1
M-phase inducer phosphatase 2	0	1	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dual specificity protein phosphatase 6	0	1	0	1
Chain A, Bacterial regulatory proteins, tetR family	0	0	1	1
caspase 7, apoptosis-related cysteine protease	2	0	0	2
caspase-3	2	0	0	2
Chain A, Cruzipain	2	0	0	2
GALC protein	1	0	0	1
glucocerebrosidase	1	0	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, Beta-lactamase	2	0	0	2
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
hexokinase	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
cellular tumor antigen p53 isoform a	2	0	0	2
Taste receptor type 2 member 38	0	0	1	2
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Ornithine decarboxylase	0	0	0	1
Ornithine decarboxylase	0	0	0	1
60 kDa chaperonin	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
60 kDa heat shock protein, mitochondrial	0	1	0	1
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
10 kDa heat shock protein, mitochondrial	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (254)

Protein Targets (740)

Ochronosis

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (254)

Drugs Studied (80)

Protein Targets (740)