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biphenylyltetrazole
A member of the class of biphenyls that consists of a biphenyl ring system substituted by a tetrazole ring at an unspecified position.
ChEBI ID: 48420
Members (7)
Member | Definition | Role |
---|---|---|
avapro | A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. | irbesartan |
candesartan | A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension. | candesartan |
exp3174 | A biphenylyltetrazole that is losartan with the hydroxymethyl group at position 5 on the imidazole ring replaced with a carboxylic acid. | losartan carboxylic acid |
losartan | A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position | losartan |
olmesartan | olmesartan | |
pratosartan | pratosartan | |
valsartan | A monocarboxylic acid amide consisting of L-valine in which the amino hydrogens have been replaced by a pentanoyl and a [2'-(1H-tetrazol-5-yl)biphenyl]-4-yl]methyl group. It exhibits antihypertensive activity. | valsartan |
Research
Studies (13,460)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 14 (0.10) | 18.7374 |
1990's | 2,154 (16.00) | 18.2507 |
2000's | 5,183 (38.51) | 29.6817 |
2010's | 4,607 (34.23) | 24.3611 |
2020's | 1,502 (11.16) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 3,128 (20.60%) | 5.53% |
Reviews | 1,296 (8.53%) | 6.00% |
Case Studies | 569 (3.75%) | 4.05% |
Observational | 99 (0.65%) | 0.25% |
Other | 10,096 (66.47%) | 84.16% |