Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR(1)R(2), where ROH is an alcohol, oxime, or phenol and R(1) is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief.
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 8.1224 | 4 | 59 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 33.8034 | 1 | 3 |
| AR protein | Homo sapiens (human) | Potency | 34.5117 | 9 | 23 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 30.8055 | 3 | 10 |
| Ataxin-2 | Homo sapiens (human) | Potency | 10.8707 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 10.8707 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 18.9262 | 2 | 4 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 33.5520 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 35.7168 | 2 | 2 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 35.7168 | 2 | 2 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 7.0632 | 2 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 24.3365 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 26.6795 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 35.5785 | 8 | 23 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 34.3219 | 2 | 6 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 37.4748 | 6 | 24 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 26.9862 | 2 | 2 |
| geminin | Homo sapiens (human) | Potency | 2.3109 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 29.0139 | 2 | 13 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 39.9852 | 3 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 48.5577 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 47.7172 | 2 | 5 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 111.8299 | 2 | 8 |
| Interferon beta | Homo sapiens (human) | Potency | 33.2940 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 0.0013 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 26.6783 | 4 | 18 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 30.3001 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 32.7228 | 3 | 33 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 0.0256 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 41.2516 | 1 | 3 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 30.5117 | 2 | 5 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 61.0886 | 2 | 10 |
| progesterone receptor | Homo sapiens (human) | Potency | 28.8471 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 33.5768 | 2 | 10 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 38.2028 | 2 | 12 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 28.4488 | 2 | 11 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 33.5875 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 27.1855 | 2 | 6 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 42.8718 | 3 | 8 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 41.4328 | 4 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 29.1936 | 2 | 5 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 30.6523 | 3 | 5 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 8.6438 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 48.5577 | 1 | 1 |