Page last updated: 2024-08-05 15:43:47

sclerotherapy agent

A sclerotherapy agent is used to treat blood vessels or blood vessel malformations (vascular malformations) and also those of the lymphatic system by injection into the vessels, which makes them shrink.

ChEBI ID: 63923

Members (1)

MemberDefinitionClass
polidocanolA hydroxypolyether that is nonaethylene glycol in which one of the terminal hydroxy functions is substituted by a lauryl (dodecyl) group.polidocanol

Research

Studies (1,166)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-1990189 (16.21)18.7374
1990's260 (22.30)18.2507
2000's265 (22.73)29.6817
2010's307 (26.33)24.3611
2020's145 (12.44)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials167 (13.45%)5.53%
Reviews66 (5.31%)6.00%
Case Studies179 (14.41%)4.05%
Observational10 (0.81%)0.25%
Other820 (66.02%)84.16%

Protein Targets (49)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
AR proteinHomo sapiens (human)Potency5.900777
Ataxin-2Homo sapiens (human)Potency2.113211
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency2.113211
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency33.491511
caspase-3Homo sapiens (human)Potency33.491511
Cellular tumor antigen p53Homo sapiens (human)Potency31.670422
cytochrome P450 2C9, partialHomo sapiens (human)Potency21.876111
cytochrome P450 2D6Homo sapiens (human)Potency12.301811
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency8.709011
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency10.590911
estrogen nuclear receptor alphaHomo sapiens (human)Potency7.771488
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency20.952122
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency3.847566
farnesoid X nuclear receptorHomo sapiens (human)Potency33.488911
GVesicular stomatitis virusPotency21.876111
gemininHomo sapiens (human)Potency30.053422
GLI family zinc finger 3Homo sapiens (human)Potency6.303022
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency25.653533
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency6.682411
heat shock protein beta-1Homo sapiens (human)Potency33.488922
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency21.876111
huntingtin isoform 2Homo sapiens (human)Potency35.481311
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency26.832511
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency21.876112
Interferon betaHomo sapiens (human)Potency21.876111
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency11.692322
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency26.832511
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency35.481312
nuclear receptor subfamily 1, group I, member 2Rattus norvegicus (Norway rat)Potency28.183811
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency17.780111
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency18.105611
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency20.525722
phosphopantetheinyl transferaseBacillus subtilisPotency70.794612
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency25.118911
pregnane X nuclear receptorHomo sapiens (human)Potency7.497811
progesterone receptorHomo sapiens (human)Potency28.600822
RAR-related orphan receptor gammaMus musculus (house mouse)Potency7.184222
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency20.898333
retinoid X nuclear receptor alphaHomo sapiens (human)Potency4.771622
SMAD family member 2Homo sapiens (human)Potency9.520511
SMAD family member 3Homo sapiens (human)Potency9.520511
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency10.044222
TDP1 proteinHomo sapiens (human)Potency6.683822
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency8.412722
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.089111
thyroid stimulating hormone receptorHomo sapiens (human)Potency26.603211
USP1 protein, partialHomo sapiens (human)Potency56.234111
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency26.832522
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency6.682411