Amebiasis, Intestinal

DYSENTERY caused by intestinal amebic infection, chiefly with ENTAMOEBA HISTOLYTICA. This condition may be associated with amebic infection of the LIVER and other distant sites.

Synonym
Intestinal Amoebiasis
Intestinal Entamoeba histolytica Infection
Dysentery, Amebic
Intestinal Amebiasis
Entamoebiasis, Intestinal
Amebiasis, Intestinal
Amebic Dysentery
Amoebic Dysentery
Amoebic Colitis
Amoebiasis, Intestinal
Colitis, Amebic

Excerpt	Reference
"Uncomplicated amebic colitis is readily treated and has a mortality rate of less than 0."	( Brooks, JL; Kozarek, RM, 1985)
"Amebic dysentery is treated with metronidazole, followed by a luminal amebicide."	( Moraes, LA; Salles, JM; Salles, MJ; Silva, MC, 2007)
"Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica."	( Dans, LF; Martínez, EG, 2007)
"Fulminant amoebic colitis is very rarely associated with chemotherapy."	( Ae, T; Hanaoka, N; Higuchi, K; Ishido, K; Koizumi, W; Saigenji, K; Sasaki, T; Tanabe, S, 2009)
"Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica."	( Mackey-Lawrence, NM; Petri, WA, 2011)
"Amoebic colitis is a rare condition in patients with SLE."	( Ju, JH; Jung, HS; Kim, HY; Kwok, SK; Lee, J; Nam, HC; Park, KS; Park, SH, 2012)
"Amebic dysentery is caused by the protozoan parasite Entamoeba histolytica and the ingestion of quadrinucleate cyst of E."	( Ahuja, V; Paul, J; Verma, AK; Verma, R, 2012)
"Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica."	( Marie, C; Petri, WA, 2013)
"Intestinal amoebiasis is a parasitic infection caused by Entamoeba histolytica."	( Habiburrahman, M; Handjari, DR; Krisnuhoni, E; Putranto, AS; Rahadiani, N; Stephanie, M, 2022)

Excerpt	Reference
"Sixty adult patients with symptomatic intestinal amoebiasis and with Entamoeba histolytica present in stools were allocated at random to treatment with tinidazole or metronidazole, both administered in a dose of 2 g once daily for 3 consecutive days."	( Devi, CS; Lavakusulu, D; Swami, B, 1977)
"Sixty patients with symptomatic intestinal amoebiasis were treated for 3 days with a single dose of 2 g of either tinidazole or metronidazole respectively by random order."	( Gupta, RC; Misra, NP, 1977)
"Forty children with symptomatic intestinal amoebiasis were treated with tinidazole in a single dose of 50 mg/kg for 3 consecutive days."	( Ahmed, T; Ali, F; Sarwar, SG, 1976)
"Asymptomatic intestinal amoebiasis was first detected after his third episode of hepatic disease, and his eventual cure followed an intensive regimen designed primarily to treat the intestinal infection."	( Gregory, PB, 1976)
"Uncomplicated amebic colitis is readily treated and has a mortality rate of less than 0."	( Brooks, JL; Kozarek, RM, 1985)
"Of 115 patients with symptomatic intestinal amebiasis, 56 were treated with Ro 7-0207 and 59 with metronidazole in a double blind study."	( Botero, D, 1974)
"In two patients, treatment of amebic dysentery was followed (despite the disappearance of the infecting organism) by an illness with the clinical, pathological, and radiological characteristics of nonspecific ulcerative colitis."	( Clark, CG; Rampton, DS; Salmon, PR, 1983)
"The diagnosis of non-dysenteric intestinal amoebiasis could be made in only one patient, who had relapse of symptoms within 6 weeks of antiamoebic therapy and therefore the relapse did not meet criteria for the diagnosis of non-dysenteric intestinal amoebiasis."	( Anand, AC; Kher, SK; Reddy, PS; Saiprasad, GS, 1997)
"He had a 50-day-history of amebic dysentery and had been treated with 1,500 mg metronidazole per day."	( Ohta, S; Santa, Y; Takase, K; Yoshimura, T, 2005)
"Six patients with severe intestinal amoebiasis treated with metronidazole retention enema are presented, and they illustrate the efficacy of the new method of therapy."	( Adesola, AO; Olumide, F, 1976)
"Nitazoxanide is effective in treating invasive intestinal amoebiasis and in eliminating E."	( El-Gohary, Y; Kabil, SM; Rossignol, JF; Younis, AM, 2007)
"Adequate therapy for amoebic colitis is necessary to reduce the severity of illness, prevent development of complicated disease and extraintestinal spread, and decrease transmission."	( Dans, LF; Gonzales, ML; Martinez, EG, 2009)
"Fulminant amoebic colitis is very rarely associated with chemotherapy."	( Ae, T; Hanaoka, N; Higuchi, K; Ishido, K; Koizumi, W; Saigenji, K; Sasaki, T; Tanabe, S, 2009)
"Stool microscopy grossly over-diagnosed intestinal amebiasis and is likely to result in unnecessary treatment with anti-protozoal drugs."	( Garg, A; Khairnar, K; Parija, SC; Priya, T; Pushpa, K, 2010)
"We present a case of amoebic colitis, misdiagnosed as inflammatory bowel disease and treated with corticosteroids, leading to severe necrotizing enterocolitis."	( Christiansen, JJ; Eivindson, MV; Larsen, CS; Mogensen, TH; Tøttrup, A, 2014)
"We present a case of intestinal amoebiasis unexpectedly revealed by colonoscopy after allogeneic bone marrow transplantation from a human leukocyte antigen-mismatched unrelated donor for acute myeloid leukemia arising from chronic myelomonocytic leukemia and successfully treated by metronidazole."	( Chiba, S; Fujisawa, S; Hagihara, M; Itabashi, M; Kato, H; Kishimoto, K; Kunisaki, R; Kuwabara, H; Motohashi, K; Numata, A; Tanaka, M, 2015)
"Adequate therapy for amoebic colitis is necessary to reduce illness, prevent development of complicated disease and extraintestinal spread, and decrease transmission."	( Dans, LF; Gonzales, MLM; Sio-Aguilar, J, 2019)
"Here, we report a case of amoebic colitis in which peripheral neuropathy occurred approximately 24 hours after administering metronidazole."	( Hotta, Y; Ikeda, K; Isozaki, Y; Nagao, Y; Oaku, T; Oyamada, H; Sekoguchi, S; Takemura, K; Yamada, N; Yamane, S, 2020)
"We report a case of fulminant amoebic colitis resulting from an asymptomatic Entamoeba histolytica infection, which was activated by chemotherapy for gastric cancer."	( Doki, Y; Eguchi, H; Hamabe, A; Hata, T; Miyoshi, N; Ogino, T; Saito, T; Sekido, Y; Takiguchi, N; Uemura, M, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	846 (82.62)	23.3326
1990's	43 (4.20)	12.5806
2000's	62 (6.05)	18.1394
2010's	58 (5.66)	28.8240
2020's	15 (1.46)	9.53

Drug	Relationship Strength	Studies	Trials
acetic acid	low	1	0
quinacrine	low	14	0
benzene	low	2	0
methane	low	1	0
chlorine	low	1	0
2-cresol	low	1	0
lactic acid	low	2	0
formaldehyde	low	1	0
hydrogen	low	1	0
iodine	low	6	0
niacin	low	2	0
4-aminobenzoic acid	low	1	0
phenanthrene	low	15	0
phenol	low	2	0
propylene glycol	low	1	0
1-propanol	medium	3	3
pyruvic acid	low	1	0
thiamine	low	1	0
oxyquinoline	low	12	0
amodiaquine	low	3	0
cetyltrimethylammonium ion	low	1	0
chloroquine	low	93	0
ciprofloxacin	low	1	0
clioquinol	medium	26	2
cloxyquin	low	1	0
dapsone	low	1	0
dichlorphenamide	low	1	0
diethylcarbamazine	low	1	0
dimercaprol	low	1	0
fluorouracil	low	2	0
furazolidone	low	6	0
gentamicin	low	1	0
glutaral	low	1	0
guaifenesin	low	6	0
iodoquinol	medium	57	1
ioxaglate	low	1	0
loperamide	medium	2	1
mebendazole	low	2	0
methenamine	low	1	0
metronidazole	medium	235	20
nalidixic acid	low	3	0
neostigmine	low	1	0
niclosamide	low	2	0
norfloxacin	low	2	0
quinone	low	4	0
phenobarbital	low	1	0
phthalylsulfathiazole	low	1	0
pipemidic acid	low	1	0
procaine	low	1	0
pyrimethamine	low	1	0
sulfadiazine	low	4	0
sodium fluoride	low	1	0
sulfamethoxazole	low	4	0
sulfanilamide	low	3	0
sulfasalazine	low	5	0
sulfathiazole	low	3	0
suramin	low	1	0
thiabendazole	low	2	0
tinidazole	medium	33	11
triclosan	low	1	0
trimethoprim	low	4	0
oxyphenonium	low	1	0
prednisolone	low	4	0
prednisone	low	4	0
chloramphenicol	low	11	0
cyanides	low	1	0
kanamycin a	low	4	0
galactose	low	2	0
carbostyril	low	1	0
niridazole	low	4	0
methylene blue	low	1	0
leucine	low	1	0
aniline	low	1	0
lactose	low	1	0
colchicine	low	2	0
ethane	low	7	0
isoprene	low	1	0
methylprednisolone	low	1	0
lawsone	low	1	0
phanquinone	low	4	0
n-vinyl-2-pyrrolidinone	low	1	0
quinoxalines	low	2	0
quinoline	low	5	0
2-methylquinoline	low	1	0
benzenearsonic acid	low	1	0
arsanilic acid	low	15	0
nitrobenzene	low	1	0
thiophenes	low	1	0
framycetin	low	6	0
arsthinol	low	4	0
carbarson	low	14	0
2-naphthol	low	1	0
ethyl acetate	low	1	0
acridines	low	1	0
thiazoles	medium	10	2
nitroblue tetrazolium	low	1	0
betamethasone	low	1	0
emetine	medium	163	2
dithiazanine	low	1	0
hematoxylin	medium	1	1
azomycin	medium	38	17
arsenamide	low	1	0
malondialdehyde	low	1	0
eosine yellowish-(ys)	medium	4	1
erythromycin stearate	low	2	0
erythromycin	low	28	0
2,2-dichloroacetamide	low	2	0
8-hydroxy-2-methylquinoline	low	2	0
diphenoxylate	low	2	0
vancomycin	low	1	0
decane	low	1	0
sabinene	low	1	0
diloxanide furoate	low	22	0
streptomycin	low	9	0
dehydroemetine	low	19	0
floxacillin	low	1	0
dihydrostreptomycin sulfate	low	2	0
teclozan	low	6	0
nimorazole	low	3	0
silver	low	1	0
technetium	low	1	0
tungsten	low	1	0
galactosamine	low	1	0
hypochlorous acid	low	1	0
barium sulfate	low	15	0
fluorine	low	2	0
trolamine salicylate	low	11	0
thiamphenicol	low	1	0
cromolyn sodium	low	1	0
ornidazole	medium	9	3
iodine	low	11	0
phenyl acetate	low	11	0
cetylpyridinium chloride anhydrous	low	1	0
tetrachloroethylene	low	1	0
acetylgalactosamine	low	5	0
nitazoxanide	medium	2	2
satranidazole	low	3	0
lamivudine	low	1	0
chloroquine diphosphate	low	5	0
thomsen-friedenreich antigen	low	1	0
glutathione disulfide	low	1	0
cephalosporin c	low	1	0
tilbroquinol	low	1	0
etofamide	medium	2	1
4,7-phenanthroline	low	5	0
1,7-phenanthroline	low	23	0
diphetarsone	low	2	0
5-methyl-8-hydroxyquinoline	low	1	0
propyromazine	low	1	0
quinfamide	medium	3	1
secnidazole	medium	5	2
bismuth iodide	low	5	0
tenax	low	1	0
carbene	low	1	0
antibiotic g 418	low	1	0
e 64	low	1	0
methotrexate	low	2	0
lonafarnib	low	1	0
borneo	low	1	0
chonemorphine	low	1	0
paromomycin	low	57	0
mexaform	low	3	0
brobenzoxaldine, broxyquinoline drug combination	low	4	0
atropine	low	1	0
cortisone	low	6	0
anisomycin	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
glycogen	low	1	0
puromycin	low	5	0
conessine	low	17	0
erythromycin ethylsuccinate	low	1	0
retinol	medium	1	1
pectins	medium	2	1
clindamycin	low	2	0
arsphenamine	low	1	0
glycosides	low	3	0
stilbenes	low	1	0
nsc 4347	low	1	0
sesquiterpenes	low	33	0
thioacetamide	low	1	0
lincomycin	low	1	0
quinine	low	1	0
sodium dodecyl sulfate	low	1	0
naphthoquinones	low	1	0
bilirubin	low	2	0
dinoprostone	low	1	0
pyrantel pamoate	low	1	0
humulene	low	2	0
codeine	low	1	0
morphine	low	1	0
cytochalasin b	low	1	0
antimony	low	5	0
barium	low	3	0
bismuth	medium	29	1
arsenic	low	53	0
sulfur	low	1	0
nitrofurazone	low	1	0
cysteine	low	1	0
proguanil	low	1	0
fumagillin	low	32	0
loa	low	1	0
chlorhexidine	low	1	0
mocetinostat	low	1	0
g(m1) ganglioside	low	1	0
pateamine a	low	1	0
carbomycin	low	3	0
oxadiazoles	low	1	0
scopolamine hydrobromide	low	1	0
enerbol	low	1	0
acid phosphatase	low	1	0
oligonucleotides	low	1	0
cellulose	low	1	0
bismuth subsalicylate	medium	1	1
tryparsamide	low	1	0
ro13-9904	low	1	0
neoarsphenamine	low	1	0
chiniofon	medium	19	1
mannans	low	1	0
piperidines	low	4	0
interleukin-8	low	4	0
colistin	low	1	0
heparitin sulfate	low	1	0
ascorbic acid	low	1	0
novobiocin	low	2	0
tetracycline	medium	34	1
chlortetracycline	low	37	0
oxytetracycline, anhydrous	medium	49	1
methacycline	low	1	0
salicylates	medium	1	1
calca protein, human	low	1	0
kaolinite	medium	3	1
agar	low	1	0
glaucarubin	low	4	0
hyaluronoglucosaminidase	low	1	0
vitamin b 12	low	1	0
lactoferrin	low	1	0
exudates	low	6	0
cyclic gmp	low	2	0
folic acid	low	1	0
ganciclovir	low	3	0
prodigiosin	low	1	0
eye	low	1	0
acetylcellulose	low	1	0
concanavalin a	low	2	0
technetium tc 99m bicisate	low	1	0
leptin	low	2	0
phenanthrenes	low	16	0

Protein Targets (1,277)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	28	0	0	28
geminin	54	0	0	54
lamin isoform A-delta10	43	0	0	43
Guanine nucleotide-binding protein G	5	0	0	5
Smad3	16	0	0	16
farnesoid X nuclear receptor	35	0	0	35
pregnane X nuclear receptor	47	0	0	47
estrogen nuclear receptor alpha	82	0	0	82
nuclear factor erythroid 2-related factor 2 isoform 1	50	0	0	50
Cellular tumor antigen p53	49	0	0	49
Spike glycoprotein	26	2	5	33
Secreted chorismate mutase	0	1	0	1
glucocorticoid receptor [Homo sapiens]	45	0	0	45
peroxisome proliferator-activated receptor delta	32	0	0	32
peroxisome proliferator activated receptor gamma	39	0	0	39
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	22	0	0	22
Cytochrome P450 1A2	0	4	0	5
Cytochrome P450 2A6	0	3	0	3
Neutrophil cytosol factor 1	0	3	0	3
Cytochrome P450 2A5	0	3	0	3
Proteasome subunit beta type-5	0	1	0	1
Luciferase	23	0	0	23
RAR-related orphan receptor gamma	44	0	0	44
GLI family zinc finger 3	50	0	0	50
AR protein	67	0	0	67
estrogen receptor 2 (ER beta)	31	0	0	31
nuclear receptor subfamily 1, group I, member 3	43	0	0	43
progesterone receptor	31	0	0	31
retinoic acid nuclear receptor alpha variant 1	58	0	0	58
retinoid X nuclear receptor alpha	47	0	0	47
aryl hydrocarbon receptor	27	0	0	27
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	41	0	0	41
v-jun sarcoma virus 17 oncogene homolog (avian)	30	0	0	30
Histone H2A.x	20	0	0	20
thyroid hormone receptor beta isoform 2	51	0	0	51
DNA repair and recombination protein RadA	0	0	1	1
Voltage-dependent calcium channel gamma-2 subunit	32	0	0	32
Sulfotransferase 1A1	0	0	0	2
Glutamate receptor 2	33	0	0	33
Sulfotransferase 1E1	0	0	0	1
Sulfotransferase 1A1	0	0	0	1
Sulfotransferase 2A1	0	0	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Genome polyprotein	0	0	1	1
USP1 protein, partial	33	0	0	33
thyroid stimulating hormone receptor	31	0	0	31
chromobox protein homolog 1	31	0	0	31
transcriptional regulator ERG isoform 3	6	0	0	6
Polyphenol oxidase 2	0	4	0	5
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Cytochrome P450 1B1	0	2	0	2
Dihydropteroate synthase	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	20	0	0	20
glp-1 receptor, partial	15	0	0	15
ATAD5 protein, partial	16	0	0	16
TDP1 protein	59	0	0	59
Microtubule-associated protein tau	25	0	0	25
euchromatic histone-lysine N-methyltransferase 2	35	0	0	35
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
DNA polymerase eta isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	20	0	0	20
Glycoprotein hormones alpha chain	3	0	0	3
hypoxia-inducible factor 1 alpha subunit	24	0	0	24
caspase 7, apoptosis-related cysteine protease	9	0	0	9
estrogen-related nuclear receptor alpha	52	0	0	52
vitamin D (1,25- dihydroxyvitamin D3) receptor	36	0	0	36
caspase-3	9	0	0	9
activating transcription factor 6	24	0	0	24
thyrotropin-releasing hormone receptor	5	0	0	5
heat shock protein beta-1	18	0	0	18
huntingtin isoform 2	13	0	0	13
nuclear receptor ROR-gamma isoform 1	20	0	0	20
Catechol O-methyltransferase	0	5	0	5
Botulinum neurotoxin type A	0	4	0	4
Methionine aminopeptidase 2	0	5	0	5
Methionine aminopeptidase 1	0	4	1	5
Integrase	0	5	0	5
15-lipoxygenase, partial	11	0	0	11
regulator of G-protein signaling 4	13	0	0	13
Bloom syndrome protein isoform 1	8	0	0	8
peripheral myelin protein 22 isoform 1	4	0	0	4
flap endonuclease 1	19	0	0	19
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	10	0	0	10
histone acetyltransferase KAT2A isoform 1	12	0	0	12
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	1	1	2
Tyrosine-protein kinase Fyn	0	1	1	2
Fibrinogen C domain-containing protein 1	0	2	0	2
Chain A, Ferritin light chain	11	0	0	11
thioredoxin reductase	23	0	0	23
aldehyde dehydrogenase 1 family, member A1	38	0	0	38
alpha-galactosidase	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	15	0	0	15
DNA topoisomerase 2-alpha	0	2	0	6
Acetylcholinesterase	0	8	0	8
Chain A, HADH2 protein	20	0	0	20
Chain B, HADH2 protein	20	0	0	20
NFKB1 protein, partial	3	0	0	3
GLS protein	10	0	0	10
cytochrome P450 family 3 subfamily A polypeptide 4	36	0	0	36
cytochrome P450 2D6	23	0	0	23
arylsulfatase A	9	0	0	9
cytochrome P450 2D6 isoform 1	10	0	0	10
D(1A) dopamine receptor	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
muscarinic acetylcholine receptor M1	9	0	0	9
Solute carrier family 22 member 1	0	12	0	16
Polyunsaturated fatty acid lipoxygenase ALOX15B	8	0	0	8
ATP-binding cassette sub-family C member 3	0	34	0	34
Multidrug resistance-associated protein 4	0	34	0	38
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
5-hydroxytryptamine receptor 4	0	4	0	4
Bile salt export pump	0	56	0	56
Albumin	0	0	1	1
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	4	0	4
Muscarinic acetylcholine receptor M2	0	9	1	13
Muscarinic acetylcholine receptor M4	0	9	1	12
Muscarinic acetylcholine receptor M1	0	7	1	10
Muscarinic acetylcholine receptor M3	0	6	1	9
Muscarinic acetylcholine receptor M4	0	6	1	9
5-hydroxytryptamine receptor 2C	0	6	0	7
Muscarinic acetylcholine receptor M5	0	7	1	10
Muscarinic acetylcholine receptor M5	0	8	1	11
Alpha-2A adrenergic receptor	0	9	1	10
Muscarinic acetylcholine receptor M2	0	7	2	12
Muscarinic acetylcholine receptor M1	0	9	1	13
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 2A	0	9	0	9
Alpha-2B adrenergic receptor	0	5	1	6
Alpha-2C adrenergic receptor	0	8	0	8
5-hydroxytryptamine receptor 1A	0	3	0	3
Muscarinic acetylcholine receptor M3	0	8	1	11
D(1A) dopamine receptor	0	2	0	2
D(1B) dopamine receptor	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	2
Sodium-dependent noradrenaline transporter	0	6	1	7
Histamine H2 receptor	0	8	2	10
Alpha-1D adrenergic receptor	0	6	0	6
5-hydroxytryptamine receptor 2A	0	6	0	6
5-hydroxytryptamine receptor 2C	0	5	0	5
5-hydroxytryptamine receptor 1B	0	3	0	3
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1F	0	2	0	2
5-hydroxytryptamine receptor 2B	0	6	0	6
5-hydroxytryptamine receptor 6	0	2	0	2
Histamine H1 receptor	0	4	1	5
Sodium-dependent serotonin transporter	0	6	0	6
5-hydroxytryptamine receptor 7	0	2	0	2
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 5B	0	2	0	2
Histamine H1 receptor	0	7	2	9
D(3) dopamine receptor	0	6	0	6
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	3
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	8	1	9
Histamine H2 receptor	15	2	1	21
D(1A) dopamine receptor	5	0	0	5
5-hydroxytryptamine receptor 6	0	4	0	4
5-hydroxytryptamine receptor 7	0	7	0	7
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Sodium-dependent dopamine transporter	0	3	0	3
Potassium voltage-gated channel subfamily H member 2	0	14	0	15
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Canalicular multispecific organic anion transporter 1	0	32	0	32
Sodium channel protein type 2 subunit alpha	0	3	0	3
Ataxin-2	26	0	0	26
Sigma non-opioid intracellular receptor 1	0	6	0	6
5-hydroxytryptamine receptor 3B	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	3	2	5
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, Histamine N-methyltransferase	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Spike glycoprotein	0	2	5	7
Replicase polyprotein 1ab	0	2	6	8
lysosomal alpha-glucosidase preproprotein	5	0	0	5
importin subunit beta-1 isoform 1	7	0	0	7
snurportin-1	7	0	0	7
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Transmembrane protease serine 2	0	2	5	7
Amyloid-beta precursor protein	1	6	0	7
Procathepsin L	0	5	5	10
Replicase polyprotein 1a	0	2	5	7
Replicase polyprotein 1ab	0	2	5	7
Replicase polyprotein 1ab	0	3	5	8
Replicase polyprotein 1ab	0	6	5	11
Cytochrome P450 2C8	0	0	0	1
Cytochrome P450 2C9	0	13	1	14
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Cytochrome P450 2J2	0	8	0	8
Angiotensin-converting enzyme 2	0	2	5	7
Steroid C26-monooxygenase	0	0	1	1
Cytochrome P450 130	0	0	1	1
Cytochrome P450 130	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	3
PAX8	0	0	0	4
Hsf1 protein	0	0	2	3
67.9K protein	16	0	0	16
hepatitis C virus polyprotein	1	0	0	1
heat shock protein 90	0	0	2	2
IDH1	19	0	0	19
caspase recruitment domain family, member 15	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	18	0	0	18
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
survival motor neuron protein isoform d	19	0	0	19
bcl-2-like protein 11 isoform 1	0	0	2	2
Bcl-2-like protein 11	0	0	0	1
Glucose transporter	0	2	0	2
Hexose transporter 1	0	2	0	2
Solute carrier family 2, facilitated glucose transporter member 1	0	3	0	3
Alpha-synuclein	10	3	0	13
TAR DNA-binding protein 43	15	0	0	15
Beta lactamase (plasmid)	0	1	0	1
30S ribosomal protein S6	0	7	1	9
30S ribosomal protein S7	0	7	1	9
50S ribosomal protein L15	0	7	1	9
50S ribosomal protein L10	0	7	1	9
50S ribosomal protein L11	0	7	1	9
50S ribosomal protein L7/L12	0	7	1	9
50S ribosomal protein L19	0	7	1	9
50S ribosomal protein L1	0	7	1	9
50S ribosomal protein L20	0	7	1	9
50S ribosomal protein L27	0	7	1	9
50S ribosomal protein L28	0	7	1	9
50S ribosomal protein L29	0	7	1	9
50S ribosomal protein L31	0	7	1	9
50S ribosomal protein L31 type B	0	7	1	9
50S ribosomal protein L32	0	7	1	9
50S ribosomal protein L33	0	7	1	9
50S ribosomal protein L34	0	7	1	9
50S ribosomal protein L35	0	7	1	9
50S ribosomal protein L36	0	7	1	9
30S ribosomal protein S10	0	7	1	9
30S ribosomal protein S11	0	7	1	9
30S ribosomal protein S12	0	7	1	9
30S ribosomal protein S13	0	7	1	9
30S ribosomal protein S16	0	7	1	9
30S ribosomal protein S18	0	7	1	9
30S ribosomal protein S19	0	7	1	9
30S ribosomal protein S20	0	7	1	9
30S ribosomal protein S2	0	7	1	9
30S ribosomal protein S3	0	7	1	9
30S ribosomal protein S4	0	7	1	9
30S ribosomal protein S5	0	7	1	9
30S ribosomal protein S8	0	7	1	9
30S ribosomal protein S9	0	7	1	9
50S ribosomal protein L13	0	7	1	9
50S ribosomal protein L14	0	7	1	9
50S ribosomal protein L16	0	7	1	9
50S ribosomal protein L23	0	7	1	9
30S ribosomal protein S15	0	7	1	9
50S ribosomal protein L17	0	7	1	9
50S ribosomal protein L21	0	7	1	9
50S ribosomal protein L30	0	7	1	9
50S ribosomal protein L6	0	7	1	9
30S ribosomal protein S14	0	7	1	9
30S ribosomal protein S17	0	7	1	9
30S ribosomal protein S1	0	7	1	9
50S ribosomal protein L18	0	7	1	9
50S ribosomal protein L2	0	7	1	9
50S ribosomal protein L3	0	7	1	9
50S ribosomal protein L24	0	7	1	9
50S ribosomal protein L4	0	7	1	9
50S ribosomal protein L22	0	7	1	9
50S ribosomal protein L5	0	7	1	9
30S ribosomal protein S21	0	7	1	9
50S ribosomal protein L25	0	7	1	9
50S ribosomal protein L36 2	0	7	1	9
thioredoxin glutathione reductase	11	0	0	11
ras-related protein Rab-9A	10	0	0	10
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	16	0	0	16
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
lethal factor (plasmid)	12	0	0	12
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	3	0	3
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	2	0	2
DNA polymerase beta	7	0	0	7
short transient receptor potential channel 6 isoform 1	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Reverse transcriptase/RNaseH	0	2	1	4
Muscarinic acetylcholine receptor	0	1	1	2
EWS/FLI fusion protein	22	0	0	22
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
pregnane X receptor	14	0	0	14
cellular tumor antigen p53 isoform a	17	0	0	17
Endolysin	0	0	2	2
Integrin beta-3	14	0	0	14
Integrin alpha-IIb	14	0	0	14
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase 12	0	5	0	8
Carbonic anhydrase 1	0	17	0	21
Carbonic anhydrase 2	0	18	2	25
Carbonic anhydrase 4	0	9	0	12
Carbonic anhydrase 6	0	9	0	13
Mu-type opioid receptor	0	8	1	12
Carbonic anhydrase 5A, mitochondrial	0	8	0	13
Carbonic anhydrase	0	7	0	8
Carbonic anhydrase 7	0	5	0	8
Carbonic anhydrase	0	3	0	5
Carbonic anhydrase 9	0	8	0	11
Carbonic anhydrase	0	4	0	6
Carbonic anhydrase	0	3	0	5
Carbonic anhydrase 15	0	8	0	9
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 14	0	5	0	8
Carbonic anhydrase 5B, mitochondrial	0	5	0	9
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
thyroid hormone receptor beta isoform a	13	0	0	13
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
ORF73	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	22	0	0	22
Chain A, Putative fructose-1,6-bisphosphate aldolase	11	0	0	11
Chain A, Cruzipain	10	0	0	10
phosphopantetheinyl transferase	15	0	0	15
vitamin D3 receptor isoform VDRA	21	0	0	21
DNA polymerase kappa isoform 1	17	0	0	17
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	2	0	0	2
Inositol monophosphatase 1	7	0	0	7
Solute carrier organic anion transporter family member 1B3	0	6	0	8
Solute carrier organic anion transporter family member 1B1	0	6	0	7
thyroid stimulating hormone receptor	17	0	0	17
nonstructural protein 1	10	0	0	10
Chain A, serum paraoxonase	0	1	0	1
Carbonic anhydrase 3	0	4	0	7
Carbonic anhydrase 13	0	4	0	5
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
SMAD family member 2	17	0	0	17
SMAD family member 3	17	0	0	17
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
mitogen-activated protein kinase 1	16	0	0	16
Caspase-2	0	0	1	1
ATPase family AAA domain-containing protein 5	22	0	0	22
interferon gamma precursor	0	0	0	2
interleukin 8	16	0	0	16
G	20	0	0	20
streptokinase A precursor	0	0	5	5
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
Interferon beta	26	0	0	26
HLA class I histocompatibility antigen, B alpha chain	20	0	0	20
Cytochrome P450 3A4	0	10	2	13
Inositol hexakisphosphate kinase 1	20	0	0	20
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cytochrome P450 2C9, partial	20	0	0	20
Chain A, JmjC domain-containing histone demethylation protein 3A	13	0	0	13
acid sphingomyelinase	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	13	0	0	13
PINK1	4	0	0	4
glucocerebrosidase	5	0	0	5
Parkin	5	0	0	5
calcineurin A1, putative	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
cytochrome P450 2C19 precursor	5	0	0	5
cytochrome P450 2C9 precursor	9	0	0	9
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	15	0	0	15
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
protein AF-9 isoform a	0	0	0	2
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	1
urokinase-type plasminogen activator precursor	10	0	0	10
plasminogen precursor	10	0	0	10
bcl-2-related protein A1	0	1	0	1
urokinase plasminogen activator surface receptor precursor	10	0	0	10
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
peripheral myelin protein 22	27	0	0	27
cytochrome P450 3A4 isoform 1	21	0	0	21
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Gamma-aminobutyric acid receptor subunit pi	21	2	0	23
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	3	0	6
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	4	0	5
Glutathione reductase, mitochondrial	0	5	0	7
72 kDa type IV collagenase	0	3	0	3
Matrix metalloproteinase-9	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	21	2	0	23
Gamma-aminobutyric acid receptor subunit delta	21	2	0	23
Gamma-aminobutyric acid receptor subunit gamma-2	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-5	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-3	21	2	0	23
Gamma-aminobutyric acid receptor subunit gamma-1	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-2	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-4	21	2	0	23
Gamma-aminobutyric acid receptor subunit gamma-3	21	2	0	23
Trypanothione reductase	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	21	2	0	23
Nuclear receptor ROR-gamma	15	0	0	15
Gamma-aminobutyric acid receptor subunit alpha-1	21	2	0	23
Gamma-aminobutyric acid receptor subunit beta-3	21	2	0	23
Gamma-aminobutyric acid receptor subunit beta-2	21	2	0	23
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Rap guanine nucleotide exchange factor 4	2	0	0	2
GABA theta subunit	21	2	0	23
Multidrug and toxin extrusion protein 1	0	6	0	6
Gamma-aminobutyric acid receptor subunit epsilon	21	2	0	23
Spermine oxidase	0	1	0	1
PPM1D protein	11	0	0	11
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	3	0	3
glucose-6-phosphate 1-dehydrogenase isoform b	0	3	0	3
Dihydrofolate reductase	0	4	0	4
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	3	3
Histidine-rich protein PFHRP-II	0	3	0	4
Spike glycoprotein	0	2	0	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
DNA ligase 1	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Cysteine proteinase falcipain 2a	0	3	0	3
Cysteine proteinase falcipain 2a	0	1	0	1
endonuclease IV	7	0	0	7
GALC protein	9	0	0	9
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	9	0	9
Cholinesterase	0	6	0	6
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
DNA gyrase subunit B	0	3	0	5
DNA gyrase subunit A	0	6	0	9
DNA gyrase subunit B	0	6	1	9
DNA topoisomerase 4 subunit A	0	2	0	2
DNA topoisomerase 4 subunit B	0	2	0	3
DNA topoisomerase 4 subunit A	0	3	0	4
Cytochrome P450 2D6	0	7	0	7
DNA gyrase subunit A	0	3	0	5
Cytochrome P450 2C19	0	3	0	4
Multidrug resistance protein MdtK	0	0	2	2
DNA gyrase subunit B	0	3	0	3
DNA gyrase subunit A	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	4
DNA topoisomerase 4 subunit A	0	2	0	2
DNA topoisomerase 4 subunit B	0	2	0	2
mu opioid receptor, partial	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	3	0	3
Fumarate hydratase	12	0	0	12
polyprotein	12	0	0	12
bromodomain adjacent to zinc finger domain 2B	14	0	0	14
LAP4	0	0	3	3
MEP2	0	0	2	2
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
delta-type opioid receptor	0	1	1	2
kappa-type opioid receptor isoform 1	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	10	0	0	10
heat shock protein HSP 90-alpha isoform 2	0	3	0	7
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
Histone deacetylase 3	0	3	0	3
Alpha-1B adrenergic receptor	0	7	1	8
Alpha-1D adrenergic receptor	0	5	1	6
Histone deacetylase 4	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	7	0	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Histone deacetylase 1	0	3	0	3
Beta-galactosidase	0	0	1	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	1	3
Carbonic anhydrase 13	0	3	0	6
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	2	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
heat shock protein 90, putative	0	0	0	4
LacZ protein (plasmid)	0	1	0	1
Caspase-7	4	0	0	4
caspase-3	4	0	0	4
C-C chemokine receptor type 6	0	1	0	1
Cytochrome P450 2D1	0	2	0	2
Cytochrome P450 2D26	0	2	0	2
Cytochrome P450 2D3	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	0	0	1
Delta-type opioid receptor	0	4	0	5
Kappa-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	7	3	11
Delta-type opioid receptor	0	6	3	10
Kappa-type opioid receptor	0	6	2	9
Mu-type opioid receptor	0	3	1	6
Cytochrome P450 2D4	0	2	0	2
Mas-related G-protein coupled receptor member X2	0	0	2	2
Chain A, Beta-lactamase	12	0	0	12
Thrombopoietin	4	0	0	4
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
muscleblind-like protein 1 isoform 1	12	0	0	12
neuropeptide S receptor isoform A	4	0	0	4
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	2
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	5	0	5
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	11	2	17
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
ATP-dependent translocase ABCB1	0	5	0	5
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	1	0	2
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
ATP-dependent phosphofructokinase	12	0	0	12
Histamine H4 receptor	0	2	2	4
Histamine H3 receptor	0	1	0	1
dopamine D1 receptor	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
M-phase phosphoprotein 8	6	0	0	6
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
neutrophil cytosol factor 1	0	2	0	2
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
Solute carrier family 2, facilitated glucose transporter member 3	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
Bile salt export pump	0	4	0	4
Myeloperoxidase	0	1	0	1
Dihydrofolate reductase	0	8	0	9
Epidermal growth factor receptor	0	5	0	5
Vascular endothelial growth factor receptor 2	0	3	0	3
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Dipeptidyl peptidase 4	0	2	0	3
Delta-type opioid receptor	0	6	1	8
Mu-type opioid receptor	0	5	1	6
Beta-carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	3	0	5
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Carbonic anhydrase 4	0	3	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
replicative DNA helicase	0	0	0	2
recombinase A	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 6	0	0	0	3
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 8	0	0	0	3
Solute carrier family 22 member 6	0	3	0	3
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier family 22 member 11	0	0	0	3
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Calpain-9	0	1	0	1
Papain	0	2	0	2
Calpain-1 catalytic subunit	0	1	0	1
Cathepsin B	0	3	0	3
Neutrophil elastase	0	1	0	1
Pro-cathepsin H	0	1	0	1
Lysosomal protective protein	0	1	0	1
Fatty acid synthase	0	1	0	1
Cathepsin S	0	1	0	1
Cruzipain	0	2	0	2
Calpain-1 catalytic subunit	0	1	0	1
Dipeptidyl peptidase 1	0	1	0	1
Liver carboxylesterase	0	1	0	1
Cysteine protease	0	3	0	3
Cysteine protease falcipain-3	0	1	0	1
Cysteine protease falcipain-3	0	1	0	1
NS5	0	0	1	1
Serine hydrolase RBBP9	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	2
Dihydroorotate dehydrogenase	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	2	0	2
serine/threonine-protein kinase PLK1	5	0	0	5
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
Albumin	0	0	6	6
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	3	0	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	2	0	2
10 kDa heat shock protein, mitochondrial	0	3	0	3
Thiosulfate sulfurtransferase	0	3	0	3
Lanosterol 14-alpha demethylase	0	2	0	2
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
exodeoxyribonuclease V subunit RecD	0	3	0	3
exodeoxyribonuclease V subunit RecB	0	4	0	4
exodeoxyribonuclease V subunit RecC	0	4	0	4
Beta-2 adrenergic receptor	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
hemoglobin subunit beta	1	0	0	1
Vpr	3	0	0	3
Solute carrier family 22 member 8	0	0	0	1
Thymidylate synthase	0	4	0	4
Aromatase	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	5	0	5
Dihydrofolate reductase	0	6	4	11
Aldo-keto reductase family 1 member B1	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Menin	0	1	1	2
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	3	0	3
Methionine aminopeptidase	0	3	0	3
Methionine aminopeptidase 1	0	1	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Thymidine kinase	0	1	0	1
ClpP	3	0	0	3
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
Glutathione reductase	0	1	0	2
Multidrug resistance-associated protein 1	0	0	0	2
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Chain E, Fibrin beta chain	0	2	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
WRN	2	0	0	2
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
alkaline phosphatase, intestinal	0	0	1	1
apical membrane antigen 1, AMA1	5	0	0	5
hypothetical protein, conserved	3	0	0	3
luciferase	2	0	0	2
pyruvate kinase	5	0	0	5
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	3	0	0	3
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
intestinal alkaline phosphatase precursor	0	0	1	1
Vif	0	1	0	1
Tat	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	2	0	4
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
Pyruvate kinase PKM	0	2	0	2
Endothelin receptor type B	3	0	0	3
Endothelin-1 receptor	3	2	0	5
phosphoglycerate kinase	3	0	0	3
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	2
transforming acidic coiled-coil-containing protein 3	0	0	0	2
Macrophage migration inhibitory factor	0	2	0	2
Adenosine receptor A1	0	1	0	2
5-hydroxytryptamine receptor 1D	0	0	0	1
Adenosine receptor A2a	0	1	0	2
Histamine H1 receptor	0	1	3	4
Metabotropic glutamate receptor 5	0	3	1	4
Glutamate receptor ionotropic, NMDA 1	0	1	0	2
Histamine H3 receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	2
Glutamate receptor ionotropic, NMDA 2B	0	1	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	2
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	2
Solute carrier family 22 member 1	0	5	0	7
Equilibrative nucleoside transporter 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	2
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	5	0	6
Glutamate receptor ionotropic, NMDA 3A	0	1	0	2
Snq2p	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	1	0	1
D(3) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	3	0	3
Alpha-2A adrenergic receptor	0	3	0	3
Sodium-dependent dopamine transporter	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	4	0	4
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Envelope glycoprotein	0	0	1	1
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Transporter	0	3	0	3
histone deacetylase 9 isoform 3	9	0	0	9
citrate synthase 2, partial	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Adenosine receptor A3	0	2	0	2
Mitogen-activated protein kinase 3	0	1	0	1
Mitogen-activated protein kinase 1	0	3	0	3
Mitogen-activated protein kinase 14	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
Capsid protein	0	1	1	2
Dihydroorotate dehydrogenase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Genome polyprotein	0	1	0	1
Protease	0	2	1	3
Histone-lysine N-methyltransferase SETD7	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 22	0	1	0	1
P2X purinoceptor 7	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	2
Phospholipase A-2-activating protein	0	1	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Vitamin D3 receptor	0	1	1	2
G-protein coupled bile acid receptor 1	0	0	1	1
Chain A, Protein farnesyltransferase alpha subunit	0	1	0	1
Chain B, Protein farnesyltransferase beta subunit	0	1	0	1
GTPase HRas	0	1	0	1
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
Geranylgeranyl transferase type-1 subunit beta	0	1	0	1
Geranylgeranyl transferase type-1 subunit beta	0	1	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Geranylgeranyl transferase type-1 subunit beta	0	1	0	1
Protein farnesyltransferase alpha subunit	0	1	0	1
CAAX farnesyltransferase subunit beta	0	1	0	1
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	0	1	1
Protein farnesyltransferase subunit beta	0	0	1	1
Cocaine esterase	0	3	0	3
Beta-2 adrenergic receptor	0	2	0	2
D(4) dopamine receptor	0	1	0	1
Nociceptin receptor	0	1	0	1
Calmodulin	0	1	1	2
Angiopoietin-1 receptor	0	1	1	2
Tyrosine-protein kinase ABL1	0	3	1	4
Proto-oncogene tyrosine-protein kinase Src	0	3	0	3
Fatty-acid amide hydrolase 1	0	2	0	2
Calmodulin-domain protein kinase 1	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	6	0	7
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	4	0	5
Thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	3	0	3
Thymidylate synthase	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	5	0	5
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	3	0	3
Kappa-type opioid receptor	0	3	1	5
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Pteridine reductase 1	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	3	0	4
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	4
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	2	0	0	2
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	2	0	0	2
caspase-3 isoform a preproprotein	0	1	0	1
POsterior Segregation	0	0	1	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Amine oxidase [flavin-containing] A	0	2	0	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
Androgen receptor	0	5	0	5
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	2	0	2
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	0	2
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Cholinesterase	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	2	0	0	2
Cholesteryl ester transfer protein	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	0	0	2
D-amino-acid oxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
pyruvate kinase PKM isoform b	1	0	0	1
Aurora kinase A	0	2	0	2
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Tyrosine-protein kinase Lyn	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Fibroblast growth factor receptor 1	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Protein kinase C alpha type	0	2	0	2
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
Signal transducer and activator of transcription 3	0	2	0	2
Mitogen-activated protein kinase 8	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Anoctamin-1	0	2	0	2
Pyruvate-flavodoxin oxidoreductase	0	1	0	1
Snake venom metalloproteinase BaP1	0	1	0	1
NAD(+) hydrolase SARM1	0	2	0	2
Chain A, Gyrase	0	0	1	1
Genome polyprotein	0	1	1	2
DNA gyrase subunit B	0	1	0	1
Heat shock protein HSP 90-alpha	0	0	2	2
Heat shock protein HSP 90-beta	0	1	2	4
DNA gyrase subunit B	0	1	0	1
Cell division inhibitor SulA	0	0	0	1
DNA gyrase subunit B	0	1	0	1
Heat shock protein HSP 90	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
DNA topoisomerase	0	1	0	1
Microtubule-associated proteins 1A/1B light chain 3B	0	2	1	3
Microtubule-associated proteins 1A/1B light chain 3A	0	2	1	3
Chain A, Bacterial leucyl aminopeptidase	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Thermolysin	0	2	0	3
Catechol O-methyltransferase	0	1	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-2	0	0	1	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 3	0	2	0	2
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Low molecular weight protein-tyrosine phosphatase A	0	1	0	1
Trace amine-associated receptor 5	0	0	3	3
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Puromycin-sensitive aminopeptidase	0	1	0	1
galactokinase	1	0	0	1
dual specificity protein phosphatase 3	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 1	0	2	0	2
Estrogen receptor	0	0	2	2
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Estrogen receptor beta	0	0	2	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
N	0	1	0	1
NPYLR7B	0	0	1	1
tumor susceptibility gene 101 protein	1	0	0	1
Major prion protein	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Aldehyde oxidase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Nicotinamide N-methyltransferase	0	1	0	1
Coagulation factor XII	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Carbon monoxide dehydrogenase small chain	0	0	1	1
Liver carboxylesterase 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Dual specificity protein phosphatase 1	0	1	0	1
Caspase-1	0	2	0	2
M-phase inducer phosphatase 2	0	1	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dual specificity protein phosphatase 6	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
shiga toxin 1 variant A subunit	1	0	0	1
shiga toxin 1 B subunit	1	0	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	2	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Eyes absent homolog 2	0	1	0	1
Tyrosinase	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	1
Prothrombin	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Trypsin-3	0	1	0	1
Protein argonaute-2	0	0	2	2
ATP-dependent 6-phosphofructokinase	0	2	0	2
Dihydropteroate synthase	0	2	0	2
Carbonic anhydrase 2	0	1	1	2
Chain A, Glutathione S-transferase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Tumor necrosis factor	0	0	1	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Thromboxane-A synthase	0	1	0	1
Flavin reductase (NADPH)	0	0	1	1
Sodium/bile acid cotransporter	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
Transcriptional activator protein LasR	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Protein arginine N-methyltransferase 6	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 2	0	1	0	1
Serine/threonine-protein kinase D3	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Protein kinase C eta type	0	1	0	1
P2Y purinoceptor 2	0	1	1	2
Protein kinase C iota type	0	1	0	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 2	0	1	1	2
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2Y purinoceptor 4	0	0	1	1
NAD-dependent protein deacetylase HST2	0	1	0	1
P2X purinoceptor 3	0	0	1	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	1	0	1
DNA primase	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
P2Y purinoceptor 6	0	1	0	1
Serine/threonine-protein kinase D1	0	1	0	1
Dual specificity protein phosphatase 5	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 8	0	1	0	1
RmtA	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 3	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
P2Y purinoceptor 11	0	1	1	2
P2X purinoceptor 7	0	0	1	1
Protein arginine N-methyltransferase 1	0	1	0	1
P2Y purinoceptor 12	0	0	1	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Stromelysin-1	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
BRCA1	1	0	0	1
P53	1	0	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	0	1	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Taste receptor type 2 member 38	0	0	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, Repressor	0	0	1	1
twin arginine protein translocation system - TatA protein	0	0	0	1
Transthyretin	0	1	1	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Endoplasmic reticulum chaperone BiP	0	1	0	1
Carbonyl reductase [NADPH] 1	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI	0	2	0	2
Enoyl-acyl carrier reductase	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
Enoyl-ACP reductase II	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(11)

Research Excerpts

Overview

Treatment

Research

Studies (1,024)

Protein Targets (1,277)

Amebiasis, Intestinal

Synonyms(11)

Research Excerpts

Overview

Treatment

Research

Studies (1,024)

Drugs Studied (283)

Protein Targets (1,277)