A substance that reduces or suppresses inflammation.
| Member | Definition | Class |
|---|
| amcinonide | | amcinonide |
| andrographolide | A labdane diterpenoid isolated from the leaves and roots of Andrographis paniculata that exhibits anti-HIV, anti-inflammatory and antineoplastic properties. | andrographolide |
| beclomethasone | A 17alpha-hydroxy steroid that is prednisolone in which the hydrogens at the 9alpha and 16beta positions are substituted by a chlorine and a methyl group, respectively. | beclomethasone |
| beclomethasone dipropionate | A steroid ester comprising beclomethasone having propionyl groups at the 17- and 21-positions. | beclomethasone dipropionate |
| betamethasone | | betamethasone |
| betamethasone valerate | A steroid ester that is betamethasone in which the hydroxy group at the 17alpha position has been converted to the corresponding pentanoate ester. | betamethasone valerate |
| celastrol | A pentacyclic triterpenoid that is 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid bearing an oxo substituent at position 2, a hydroxy substituent at position 3 and two methyl groups at positions 9 and 13. An antioxidant and anti-inflammatory agent. Potently inhibits lipid peroxidation in mitochondria and inhibits TNF-alpha-induced NFkappaB activation. Also shown to inhibit topoisomerase II activity in vitro (IC50 = 7.41 muM). | celastrol |
| clobetasol | A 3-oxo-Delta(1),Delta(4)-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis. | clobetasol |
| clobetasol propionate | The 17-O-propionate ester of clobetasol. A potent corticosteroid, it is used to treat various skin disorders, including exzema and psoriasis. | clobetasol propionate |
| clocortolone pivalate | The 21-O-pivalate ester of clocortolone. It is used for the relief of inflammatory and pruritic (itching) skin disorders. | clocortolone pivalate |
| dapsone | A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. | dapsone |
| delgocitinib | A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted by a (3S,4R)-1-(cyanoacetyl)-3-methyl-1,6-diazaspiro[3.4]octan-6-yl group at position 4. It is a pan-Janus kinase (JAK) inhibitor and is approved for treatment of atopic dermatitis (AD) in Japan. | delgocitinib |
| desonide | Triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders. | desonide |
| desoximetasone | Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis. | desoximetasone |
| diflorasone | The 16beta-analogue of flumethasone. It is used as the 17,21-diacetate as a topical anti-inflammatory and antipruritic in the treatment of various skin disorders. | diflorasone |
| diflorasone diacetate | The 17,21-diacetate derivative of diflorasone. It is used topically for its anti-inflammatory and antipruritic properties in the treatment of various skin disorders. | diflorasone diacetate |
| e 3040 | A member of the class of benzothiazoles that is 1,3-benzothiazole substituted by a methylnitrilo group, (pyridin-3-yl)methyl group, methyl group, hydroxy group and methyl group at position 2,4,5,6 and 7, respectively. It is a dual inhibitor of 5-lipoxygenase and thromboxane A2 synthetase and exhibits anti-inflammatory properties. The drug was being developed by Eisai (Tokyo, Japan) for the treatment of bowel disease. | E3040 |
| ebselen | A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. | ebselen |
| fludrocortisone | | fludrocortisone |
| flumethasone | | flumethasone |
| flumethasone pivalate | | flumethasone pivalate |
| flunisolide | | flunisolide |
| fluocinolone acetonide | A fluorinated steroid that is flunisolide in which the hydrogen at position 9 is replaced by fluorine. A corticosteroid with glucocorticoid activity, it is used (both as the anhydrous form and as the dihydrate) in creams, gels and ointments for the treatment of various skin disorders. | fluocinolone acetonide |
| fluorometholone | A member of the class of glucocorticoids that is Delta(1)-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe. | fluorometholone |
| fluticasone propionate | A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a propionyl substituent at position 17; has anti-inflammatory, anti-asthmatic and anti-allergic activity. | fluticasone propionate |
| friedelin | A pentacyclic triterpenoid that is perhydropicene which is substituted by an oxo group at position 3 and by methyl groups at the 4, 4a, 6b, 8a, 11, 11, 12b, and 14a-positions (the 4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS-enantiomer). It is the major triterpenoid constituent of cork. | friedelin |
| ginsenoside rb1 | A ginsenoside found in Panax ginseng and Panax japonicus var. major that is ginsenoside Rd in which the beta-D-glucopyranoside group at position 20 is replaced by a beta-D-glucopyranosyl-beta-D-glucopyranoside group. | ginsenoside Rb1 |
| ginsenoside rd | A ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. | ginsenoside Rd |
| hydrocortamate | | hydrocortamate |
| loteprednol etabonate | | loteprednol etabonate |
| lupeol | A pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in many edible fruits and vegetables. | lupeol |
| methylprednisolone | The 6alpha-stereoisomer of 6-methylprednisolone. | 6alpha-methylprednisolone |
| methylprednisolone acetate | An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid. | methylprednisolone acetate |
| mometasone furoate | | mometasone furoate |
| palmidrol | An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid. | palmitoyl ethanolamide |
| prednisolone | A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone. | prednisolone |
| prednisolone hemisuccinate | A hemisuccinate resulting from the formal condensation of the 21-hydroxy group prednisolone with one of the carboxy groups of succinic acid. It is used to treat mild to moderate non-infectious eye allergies and inflammation, including damage caused by chemical and thermal burns. | prednisolone succinate |
| prednisolone sodium succinate | The organic sodium salt of prednisolone succinate. | prednisolone sodium succinate |
| prednisone | A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid. | prednisone |
| probucol | A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood. | probucol |
| pulmicort | A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis. | budesonide |
| rizatriptan | | rizatriptan |
| sar 1118 | An N-acyl-L-alpha-amino acid obtained by formal condensation of the carboxy group of N-[2-(1-benzofuran-6-carbonyl)]-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid with the amino group of 3-(methanesulfonyl)-L-phenylalanine. Used for treatment of keratoconjunctivitis sicca (dry eye syndrome). | lifitegrast |
| sch 22219 | A prednisolone compound having an alpha-chloro substituent at the 7-position, an alpha-methyl substituent at the 16-position and O-propanoyl groups at the 17- and 21-positions. | alclometasone dipropionate |
| triamcinolone | A C21-steroid hormone that is 1,4-pregnadiene-3,20-dione carrying four hydroxy substituents at positions 11beta, 16alpha, 17alpha and 21 as well as a fluoro substituent at position 9. Used in the form of its 16,17-acetonide to treat various skin infections. | triamcinolone |
| triamcinolone acetonide | A synthetic glucocorticoid that is the 16,17-acetonide of triamcinolone. Used to treat various skin infections. | triamcinolone acetonide |
| varespladib | A member of the class of indoles that is 1H-indole substituted by benzyl, ethyl, oxamoyl, and carboxymethoxy groups at positions 1, 2, 3, and 4, respectively. It is an oral secretory phospholipase A2 inhibitor and exhibits anti-inflammatory effects. | varespladib |
| varespladib methyl | A methyl ester resulting from the formal condensation of the carboxy group of varespladib with methanol. It is a potential therapy for the treatment of snakebite envenomings in which toxicity depends on the action of PLA2s. | varespladib methyl |
| vx-745 | A member of the class of pyrimidopyridazines that is 6H-pyrimido[1,6-b]pyridazin-6-one substituted at positions 2 and 5 by (2,4-difluorophenyl)sulfanyl and 2,6-dichlorophenyl groups respectively | VX-745 |
| zolmitriptan | A member of the class of tryptamines that is N,N-dimethyltryptamine in which the hydrogen at position 5 of the indole ring has been replaced by a [(4S)-2-oxo-1,3-oxazolidin-4-yl]methyl group. A serotonin 5-HT1 B and D receptor agonist, it is used for the treatment of migraine. | zolmitriptan |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 0.5646 | 1 | 3 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 0.2306 | 1 | 2 |
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Leishmania major strain Friedlin | Potency | 7.5686 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 13.8894 | 2 | 6 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 31.3416 | 2 | 3 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 22.0840 | 2 | 4 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 3.0003 | 1 | 6 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 32.4648 | 2 | 2 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 4.4780 | 1 | 3 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 3.6503 | 12 | 329 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 11.3109 | 2 | 20 |
| arylsulfatase A | Homo sapiens (human) | Potency | 1.0691 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 8.1758 | 3 | 5 |
| Ataxin-2 | Homo sapiens (human) | Potency | 0.0250 | 1 | 11 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 12.1337 | 3 | 5 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 0.6481 | 2 | 13 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 6.7456 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 26.1216 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 0.0045 | 2 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 42.6696 | 1 | 4 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 29.8493 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 33.4915 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 29.8493 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 33.4915 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 26.7616 | 2 | 9 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 11.9443 | 1 | 4 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 33.9898 | 2 | 12 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 28.2665 | 2 | 4 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 12.5893 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 10.4195 | 2 | 8 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 15.4412 | 1 | 6 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 22.6655 | 3 | 5 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 9.0630 | 1 | 7 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 10.4195 | 2 | 8 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 60.2754 | 2 | 8 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 0.8554 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 0.6246 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 15.1833 | 1 | 17 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 17.4934 | 1 | 9 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 5.5000 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 12.9878 | 2 | 10 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 11.9628 | 2 | 30 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 2.2244 | 1 | 40 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 30.3001 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 4.7444 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 39.2615 | 1 | 3 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 10.1812 | 10 | 151 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 46.3997 | 2 | 6 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 26.5874 | 8 | 75 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 29.5917 | 1 | 15 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 12.9170 | 4 | 19 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 26.3808 | 2 | 4 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 64.2145 | 1 | 5 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 22.3872 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 14.6536 | 1 | 2 |
| G | Vesicular stomatitis virus | Potency | 15.1833 | 1 | 17 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| GALC protein | Homo sapiens (human) | Potency | 2.5873 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 12.9878 | 1 | 5 |
| geminin | Homo sapiens (human) | Potency | 11.4367 | 4 | 30 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 16.4994 | 3 | 36 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 14.3918 | 1 | 8 |
| GLS protein | Homo sapiens (human) | Potency | 8.0141 | 2 | 4 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 34.3725 | 1 | 4 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 0.3578 | 5 | 123 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 8.9329 | 1 | 7 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 11.3852 | 1 | 3 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 22.7496 | 1 | 3 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 21.8892 | 2 | 5 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 0.6066 | 2 | 13 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 0.4496 | 1 | 4 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 111.5860 | 2 | 3 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 15.1833 | 1 | 17 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 20.8954 | 1 | 2 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 11.1471 | 4 | 5 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 9.0485 | 2 | 8 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 3.5236 | 3 | 31 |
| IDH1 | Homo sapiens (human) | Potency | 10.3508 | 1 | 12 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 11.3852 | 1 | 3 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 15.1833 | 1 | 34 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 8.0036 | 3 | 38 |
| interleukin 8 | Homo sapiens (human) | Potency | 66.8242 | 1 | 1 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 25.1998 | 2 | 6 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 9.9073 | 1 | 10 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 10.6530 | 1 | 3 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 21.0236 | 3 | 6 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 18.0789 | 3 | 5 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 2.9006 | 2 | 4 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 4.0027 | 1 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 10.3260 | 2 | 10 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.0891 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 40.3582 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 2.9006 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 2.9006 | 1 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 5.7738 | 5 | 7 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 4.0554 | 2 | 8 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 3.8263 | 1 | 5 |
| Nrf2 | Homo sapiens (human) | Potency | 29.2953 | 2 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 32.1519 | 3 | 21 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 0.0579 | 2 | 24 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 14.9300 | 1 | 5 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 20.4946 | 1 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 18.3093 | 4 | 18 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 7.5570 | 1 | 21 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 27.0964 | 3 | 11 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 85.0323 | 1 | 4 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 68.0131 | 1 | 3 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 28.6954 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 54.7470 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 30.1033 | 3 | 11 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 27.7547 | 4 | 8 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 2.6383 | 1 | 4 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 6.5629 | 1 | 6 |
| polyprotein | Zika virus | Potency | 14.6536 | 1 | 2 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 2.8371 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 0.5661 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 24.0387 | 1 | 3 |
| PPM1D protein | Homo sapiens (human) | Potency | 3.1481 | 1 | 8 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 21.2835 | 3 | 37 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 23.8165 | 1 | 3 |
| progesterone receptor | Homo sapiens (human) | Potency | 8.3267 | 3 | 63 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 15.5513 | 5 | 5 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 5.1189 | 4 | 4 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 22.4535 | 2 | 25 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 1.0000 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 14.4270 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 36.2145 | 3 | 37 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 29.3017 | 3 | 16 |
| RGS12 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 20.4054 | 2 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 14.8365 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Potency | 5.7988 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 19.9912 | 2 | 15 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 19.9912 | 2 | 15 |
| Smad3 | Homo sapiens (human) | Potency | 10.2756 | 1 | 5 |
| snurportin-1 | Homo sapiens (human) | Potency | 11.3852 | 1 | 3 |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 28.9003 | 1 | 3 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 1.4846 | 1 | 6 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 17.5727 | 1 | 4 |
| TDP1 protein | Homo sapiens (human) | Potency | 15.9524 | 2 | 50 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 33.0846 | 1 | 3 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 39.1287 | 3 | 8 |
| Thrombopoietin | Homo sapiens (human) | Potency | 1.5862 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 34.0554 | 2 | 19 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 23.0397 | 5 | 9 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 6.5629 | 1 | 6 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 6.5629 | 1 | 6 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 21.3018 | 2 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 36.9669 | 2 | 11 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 18.6997 | 4 | 14 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 37.8765 | 1 | 6 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 8.9329 | 1 | 7 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 2.2555 | 2 | 2 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | IC50 | 0.3572 | 2 | 2 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 0.1589 | 3 | 4 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | IC50 | 0.0236 | 2 | 2 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | Ki | 0.0072 | 2 | 2 |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | IC50 | 0.0311 | 3 | 3 |
| 5-hydroxytryptamine receptor 1D | Sus scrofa (pig) | IC50 | 0.0501 | 1 | 1 |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | Ki | 0.0106 | 4 | 6 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 7.9433 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 6.3096 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 8.9716 | 2 | 2 |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | IC50 | 3.9811 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | IC50 | 3.9811 | 1 | 1 |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 0.1830 | 1 | 1 |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase | Plasmodium berghei | IC50 | 12.4100 | 1 | 1 |
| 85/88 kDa calcium-independent phospholipase A2 | Homo sapiens (human) | IC50 | 3.0076 | 8 | 8 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 28.0050 | 2 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 8.5470 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 4.8310 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 20.4040 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 20.2360 | 1 | 1 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 8.5470 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 4.8310 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 8.5470 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 4.8310 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 34.1670 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 12.8130 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 31.8860 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 14.5570 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | IC50 | 0.0290 | 1 | 1 |
| Androgen receptor | Homo sapiens (human) | IC50 | 18.0000 | 2 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 12.3918 | 3 | 7 |
| Androgen receptor | Homo sapiens (human) | Ki | 2.6807 | 3 | 3 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 5.5625 | 1 | 4 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Arrestin, beta 1 | Homo sapiens (human) | IC50 | 1.5240 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 113.4020 | 1 | 10 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 0.7575 | 4 | 4 |
| Bile acid receptor | Homo sapiens (human) | IC50 | 9.7000 | 2 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 181.1304 | 6 | 28 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 517.5000 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 10 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Ki | 5.0000 | 2 | 3 |
| Cannabinoid receptor 2 | Homo sapiens (human) | Ki | 5.0000 | 2 | 3 |
| Caspase-1 | Homo sapiens (human) | IC50 | 4.0400 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 10.4740 | 2 | 2 |
| Cocaine esterase | Homo sapiens (human) | IC50 | 1.9000 | 1 | 1 |
| Corticosteroid-binding globulin | Homo sapiens (human) | Ki | 0.0309 | 1 | 1 |
| Corticotropin-releasing factor receptor 2 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 30.4940 | 3 | 5 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 36.4900 | 1 | 3 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 15.0517 | 4 | 4 |
| Cytochrome P450 3A5 | Homo sapiens (human) | IC50 | 3.1692 | 5 | 5 |
| Dihydrofolate reductase | Pneumocystis carinii | IC50 | 1.5000 | 1 | 1 |
| DNA topoisomerase 1 | Homo sapiens (human) | IC50 | 250.0000 | 1 | 2 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | IC50 | 190.1000 | 2 | 4 |
| dual specificity protein phosphatase 6 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 32.5000 | 3 | 4 |
| Estrogen receptor | Homo sapiens (human) | Ki | 3.6667 | 3 | 3 |
| Estrogen receptor beta | Homo sapiens (human) | IC50 | 32.5000 | 3 | 4 |
| Estrogen receptor beta | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 1.1500 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 1.1500 | 1 | 1 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Ki | 51.8300 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 5.0119 | 1 | 1 |
| galanin receptor type 3 | Homo sapiens (human) | IC50 | 29.9000 | 1 | 1 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | IC50 | 0.7420 | 5 | 5 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 0.0541 | 46 | 62 |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0258 | 6 | 7 |
| Glucocorticoid receptor | Homo sapiens (human) | Ki | 0.0210 | 17 | 30 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | Ki | 540.5000 | 1 | 1 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 13.2000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 15.0867 | 3 | 3 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0913 | 1 | 14 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 0.0415 | 1 | 14 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0913 | 1 | 14 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.0415 | 1 | 14 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0913 | 1 | 14 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.0415 | 1 | 14 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | IC50 | 0.0913 | 1 | 14 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | Ki | 0.0415 | 1 | 14 |
| Group 10 secretory phospholipase A2 | Homo sapiens (human) | IC50 | 0.0918 | 8 | 8 |
| Group 10 secretory phospholipase A2 | Mus musculus (house mouse) | IC50 | 0.0750 | 2 | 2 |
| Group 3 secretory phospholipase A2 | Homo sapiens (human) | IC50 | 0.1225 | 2 | 2 |
| Group IID secretory phospholipase A2 | Homo sapiens (human) | IC50 | 0.1017 | 3 | 3 |
| Group IID secretory phospholipase A2 | Mus musculus (house mouse) | IC50 | 0.4300 | 1 | 1 |
| Group IIE secretory phospholipase A2 | Homo sapiens (human) | IC50 | 0.0862 | 4 | 4 |
| Group IIE secretory phospholipase A2 | Mus musculus (house mouse) | IC50 | 0.0750 | 2 | 2 |
| Group IIF secretory phospholipase A2 | Homo sapiens (human) | IC50 | 0.1250 | 3 | 3 |
| Group IIF secretory phospholipase A2 | Mus musculus (house mouse) | IC50 | 1.6000 | 1 | 1 |
| Group XIIA secretory phospholipase A2 | Homo sapiens (human) | IC50 | 0.1225 | 2 | 2 |
| Group XIIB secretory phospholipase A2-like protein | Homo sapiens (human) | IC50 | 0.1225 | 2 | 2 |
| hexokinase | Trypanosoma brucei brucei TREU927 | IC50 | 0.9009 | 1 | 1 |
| Hexokinase-2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 3.4000 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 6.5333 | 3 | 3 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 3.7000 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 0.7300 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | IC50 | 0.2500 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 8.4100 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Ki | 0.0940 | 3 | 3 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 33.3520 | 3 | 3 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Integrin alpha-L | Homo sapiens (human) | IC50 | 0.0415 | 2 | 2 |
| Integrin beta-2 | Homo sapiens (human) | IC50 | 0.0415 | 2 | 2 |
| Intercellular adhesion molecule 1 | Homo sapiens (human) | IC50 | 0.0287 | 3 | 3 |
| Interleukin-5 | Homo sapiens (human) | IC50 | 26.8000 | 1 | 1 |
| Interleukin-5 | Mus musculus (house mouse) | IC50 | 26.5375 | 8 | 8 |
| Interleukin-5 receptor subunit alpha | Mus musculus (house mouse) | IC50 | 26.2000 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 250.0000 | 1 | 2 |
| L-ornithine N(5)-monooxygenase | Aspergillus fumigatus Af293 | IC50 | 11.0000 | 2 | 2 |
| large T antigen | Betapolyomavirus macacae | IC50 | 13.9100 | 1 | 1 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | IC50 | 0.2100 | 1 | 1 |
| Liver carboxylesterase 1 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 2.4000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 0.5700 | 2 | 2 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Matrix metalloproteinase-9 | Homo sapiens (human) | IC50 | 1.9890 | 1 | 1 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 2.4300 | 1 | 1 |
| Mineralocorticoid receptor | Homo sapiens (human) | IC50 | 0.0463 | 6 | 7 |
| Mineralocorticoid receptor | Homo sapiens (human) | Ki | 0.0186 | 2 | 2 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | IC50 | 0.2462 | 5 | 5 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Ki | 0.1104 | 2 | 2 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | IC50 | 0.0577 | 4 | 4 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | IC50 | 0.0577 | 4 | 4 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 1.8567 | 15 | 17 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Mus musculus (house mouse) | IC50 | 0.0442 | 2 | 4 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| MPI protein | Homo sapiens (human) | IC50 | 0.2905 | 2 | 2 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0008 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 114.1970 | 1 | 10 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 0.4200 | 1 | 1 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | IC50 | 1.6000 | 1 | 1 |
| neutrophil cytosol factor 1 | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Neutrophil cytosol factor 1 | Homo sapiens (human) | Ki | 125.0000 | 3 | 3 |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | IC50 | 0.0533 | 3 | 3 |
| Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | IC50 | 49.6000 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 3.4100 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 1.1010 | 1 | 1 |
| Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | Homo sapiens (human) | IC50 | 13.3000 | 1 | 1 |
| phosphoethanolamine/phosphocholine phosphatase isoform 1 | Homo sapiens (human) | IC50 | 0.1110 | 1 | 1 |
| Phospholipase A2 | Homo sapiens (human) | IC50 | 0.3668 | 6 | 6 |
| Phospholipase A2 | Mus musculus (house mouse) | IC50 | 0.1400 | 2 | 2 |
| Phospholipase A2 group V | Homo sapiens (human) | IC50 | 0.2738 | 5 | 5 |
| Phospholipase A2 group V | Mus musculus (house mouse) | IC50 | 0.7500 | 2 | 2 |
| Phospholipase A2, major isoenzyme | Sus scrofa (pig) | IC50 | 0.0480 | 2 | 2 |
| Phospholipase A2, membrane associated | Homo sapiens (human) | IC50 | 0.0527 | 11 | 11 |
| Phospholipase A2, membrane associated | Mus musculus (house mouse) | IC50 | 0.0700 | 2 | 2 |
| phosphomannomutase 2 | Homo sapiens (human) | IC50 | 0.6720 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 0.1650 | 2 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| procathepsin L isoform 1 preproprotein | Homo sapiens (human) | IC50 | 50.0000 | 2 | 2 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 4.5161 | 7 | 8 |
| Progesterone receptor | Homo sapiens (human) | Ki | 5.4286 | 7 | 7 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 2.1000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Ki | 5.0000 | 1 | 2 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 3.0000 | 2 | 2 |
| Putative inactive group IIC secretory phospholipase A2 | Homo sapiens (human) | IC50 | 0.1225 | 2 | 2 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase epsilon | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase eta | Homo sapiens (human) | IC50 | 111.5000 | 1 | 1 |
| Regulator of G-protein signaling 17 | Homo sapiens (human) | IC50 | 27.9338 | 5 | 5 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 5.3350 | 2 | 2 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 0.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 2.2750 | 14 | 16 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 4.4920 | 3 | 5 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | Ki | 4.2000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | Ki | 4.2000 | 2 | 2 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| RNA polymerase beta subunit (EC 2.7.7.6), partial | Escherichia coli | IC50 | 11.6872 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 8.0980 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 6.4340 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 20.4040 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 20.2360 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 27.1000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 2.9512 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | Ki | 1.6200 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | IC50 | 1.1482 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 0.8700 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 0.6700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6700 | 1 | 1 |
| Structural capsid protein | Human immunodeficiency virus 1 | IC50 | 0.0467 | 1 | 1 |
| Sulfhydryl oxidase 1 | Homo sapiens (human) | IC50 | 5.4000 | 1 | 1 |
| Telomerase reverse transcriptase | Homo sapiens (human) | IC50 | 0.7800 | 1 | 1 |
| Thromboxane-A synthase | Rattus norvegicus (Norway rat) | IC50 | 0.0900 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 0.0495 | 2 | 2 |
| Toxin B | Clostridioides difficile | IC50 | 0.0172 | 1 | 1 |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | IC50 | 5.2900 | 2 | 2 |
| TPA: protein transporter TIM23 | Saccharomyces cerevisiae S288C | IC50 | 7.8900 | 2 | 2 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Tryptophan 2,3-dioxygenase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | IC50 | 0.0203 | 6 | 6 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | IC50 | 0.0745 | 6 | 6 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | IC50 | 0.0220 | 3 | 3 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 5.8000 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 4.8680 | 5 | 5 |
| Tyrosine-protein phosphatase non-receptor type 11 | Homo sapiens (human) | IC50 | 3.5667 | 3 | 3 |
| Tyrosine-protein phosphatase non-receptor type 2 | Homo sapiens (human) | IC50 | 20.9000 | 2 | 2 |
| Tyrosine-protein phosphatase non-receptor type 6 | Homo sapiens (human) | IC50 | 15.4500 | 2 | 2 |
| Tyrosine-protein phosphatase non-receptor type 7 | Homo sapiens (human) | IC50 | 75.7000 | 1 | 1 |
| Ubiquitin carboxyl-terminal hydrolase 15 | Homo sapiens (human) | IC50 | 31.4000 | 1 | 5 |
| Ubiquitin carboxyl-terminal hydrolase 2 | Homo sapiens (human) | IC50 | 31.4000 | 1 | 5 |
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 | Homo sapiens (human) | IC50 | 31.4000 | 1 | 5 |
| Ubiquitin carboxyl-terminal hydrolase isozyme L3 | Homo sapiens (human) | IC50 | 31.4000 | 1 | 5 |
| Ubiquitin carboxyl-terminal hydrolase isozyme L5 | Homo sapiens (human) | IC50 | 31.4000 | 1 | 5 |
| UDP-glucose 4-epimerase | Homo sapiens (human) | IC50 | 0.0140 | 1 | 1 |
| Uracil nucleotide/cysteinyl leukotriene receptor | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 30.4725 | 4 | 4 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 30.4725 | 4 | 4 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Vascular cell adhesion protein 1 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | EC50 | 0.0157 | 1 | 1 |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | EC50 | 0.0057 | 2 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | EC50 | 0.0168 | 1 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | EC50 | 0.0168 | 1 | 2 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | EC50 | 0.0168 | 1 | 2 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Activin receptor type-2A | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0070 | 1 | 2 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0070 | 1 | 2 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0070 | 1 | 2 |
| Angiopoietin-1 receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 4.6700 | 1 | 1 |
| Ankyrin repeat and protein kinase domain-containing protein 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Atypical kinase COQ8B, mitochondrial | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Aurora kinase A | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Aurora kinase B | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Aurora kinase C | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum 3D7 | Kd | 10.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Casein kinase I isoform alpha-like | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cell division control protein 2 homolog | Plasmodium falciparum 3D7 | Kd | 10.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| cGMP-dependent protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 11A | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 11B | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 15 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 19 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase-like 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Cyclin-dependent kinase-like 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Cyclin-dependent kinase-like 3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Cyclin-dependent kinase-like 5 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cytochrome P450 3A5 | Homo sapiens (human) | Kd | 0.1000 | 1 | 1 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Death-associated protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Death-associated protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Death-associated protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 3 | 3 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| eIF-2-alpha kinase GCN2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 7.3500 | 2 | 2 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 7.3667 | 3 | 3 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 10.0000 | 3 | 3 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 7.3000 | 3 | 3 |
| Ephrin type-A receptor 6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | Kd | 7.7000 | 3 | 3 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | Kd | 5.9333 | 3 | 3 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 7.0000 | 3 | 3 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 10.0000 | 22 | 22 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 1.1000 | 2 | 2 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | Kd | 10.0000 | 4 | 4 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| G protein-coupled receptor kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| G-protein coupled bile acid receptor 1 | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | Kd | 4.1000 | 2 | 2 |
| Glucocorticoid receptor | Homo sapiens (human) | EC50 | 0.0259 | 46 | 47 |
| Glucocorticoid receptor | Mus musculus (house mouse) | EC50 | 0.0046 | 2 | 2 |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0102 | 2 | 2 |
| Glucocorticoid receptor | Homo sapiens (human) | Kd | 0.0290 | 1 | 1 |
| Glutamine synthetase | Homo sapiens (human) | EC50 | 0.0320 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Heat shock factor protein 1 | Homo sapiens (human) | EC50 | 1.8500 | 2 | 2 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 10.0000 | 4 | 4 |
| hexokinase HKDC1 | Homo sapiens (human) | EC50 | 38.8000 | 1 | 1 |
| hexokinase-1 isoform HKI | Homo sapiens (human) | EC50 | 41.9000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | EC50 | 0.0026 | 1 | 1 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Hormonally up-regulated neu tumor-associated kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Insulin receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Insulin receptor-related protein | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| L-ornithine N(5)-monooxygenase | Aspergillus fumigatus Af293 | Kd | 1.4000 | 2 | 2 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Leukotriene C4 synthase | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | Kd | 2.6000 | 2 | 2 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | Kd | 10.0000 | 15 | 15 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Microtubule-associated serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mineralocorticoid receptor | Homo sapiens (human) | EC50 | 0.0023 | 3 | 3 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 0.1027 | 3 | 3 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Kd | 10.0000 | 3 | 3 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 0.0029 | 4 | 4 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase 6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 13 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 15 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Myosin light chain kinase family member 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Myosin light chain kinase, smooth muscle | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Myosin-IIIa | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Myosin-IIIb | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Myotonin-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Nociceptin receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0034 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 10.0000 | 3 | 3 |
| NT-3 growth factor receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 12.2600 | 3 | 5 |
| Nuclear receptor subfamily 1 group I member 2 | Rattus norvegicus (Norway rat) | EC50 | 4.8000 | 1 | 3 |
| Nuclear receptor subfamily 4 group A member 1 | Homo sapiens (human) | Kd | 0.3000 | 3 | 3 |
| ORF73 | Human gammaherpesvirus 8 | EC50 | 75.0000 | 1 | 1 |
| Peripheral plasma membrane protein CASK | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | Kd | 10.0000 | 12 | 12 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | Kd | 9.4000 | 2 | 2 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 5.8900 | 3 | 3 |
| Procathepsin L | Homo sapiens (human) | EC50 | 4.6700 | 1 | 1 |
| Progesterone receptor | Homo sapiens (human) | Kd | 0.0001 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Protein kinase C epsilon type | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Protein kinase C eta type | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 10.0000 | 6 | 6 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 3.9933 | 3 | 3 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Receptor-interacting serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 10.0000 | 12 | 12 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 4.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 4.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 4.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 4.6700 | 2 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 4.6700 | 2 | 2 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Rhodopsin kinase GRK7 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 10.0000 | 4 | 4 |
| Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | Kd | 10.0000 | 4 | 4 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 10.0000 | 4 | 4 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 10.0000 | 4 | 4 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 10.0000 | 4 | 4 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 17B | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 25 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 32A | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase 32B | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 32C | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 35 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase 36 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 10.0000 | 4 | 4 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase DCLK3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase MAK | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase OSR1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PknB | Mycobacterium tuberculosis H37Rv | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PRP4 homolog | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase RIO1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase RIO2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase RIO3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase TNNI3K | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase VRK2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Signal transducer and activator of transcription 3 | Homo sapiens (human) | EC50 | 10.0000 | 5 | 5 |
| SNF-related serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 4.6700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 4.6700 | 1 | 1 |
| SRSF protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| SRSF protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| SRSF protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 | 1.5190 | 1 | 1 |
| Testis-specific serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Transient receptor potential cation channel subfamily M member 6 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | EC50 | 10.0000 | 2 | 2 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 4.6700 | 1 | 1 |
| Tubulin alpha-1A chain | Rattus norvegicus (Norway rat) | Kd | 10.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 6.8361 | 28 | 28 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 1.3400 | 3 | 3 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | Kd | 3.1000 | 2 | 2 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 1.2667 | 3 | 3 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 7.7667 | 3 | 3 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 2.1000 | 2 | 2 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 10.0000 | 3 | 3 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 10.0000 | 3 | 3 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 3.6667 | 3 | 3 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 1.7000 | 2 | 2 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase receptor Tie-1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase Srms | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase TXK | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 1.9333 | 3 | 3 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Kd | 6.0800 | 1 | 1 |
| Uncharacterized serine/threonine-protein kinase SBK3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Wee1-like protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |