Page last updated: 2024-08-05 11:20:36

pyrazolidines

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ChEBI ID: 38312

Members (8)

MemberDefinitionRole
2-Chloro-1-[5-(furan-2-yl)-3-(5-methylfuran-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one2-Chloro-1-[5-(furan-2-yl)-3-(5-methylfuran-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one
3-(2-furanyl)-2-methylsulfonyl-5-thiophen-2-yl-3,4-dihydropyrazole3-(2-furanyl)-2-methylsulfonyl-5-thiophen-2-yl-3,4-dihydropyrazole
kebuzoneA pyrazolidine that is phenylbutazone in which the two methylene hydrogens at postion 3 on the butyl chain are replaced by an oxo group.kebuzone
mofebutazoneA pyrazolidine that is phenylbutazone lacking one of the phenyl substituents. It is used for treatment of joint and muscular pain.mofebutazone
oxyphenbutazoneA metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.oxyphenbutazone
phenylbutazoneA member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.phenylbutazone
sulfinpyrazonesulfinpyrazone
suxibuzoneA pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.suxibuzone

Research

Studies (7,445)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19906,727 (90.36)18.7374
1990's328 (4.41)18.2507
2000's217 (2.91)29.6817
2010's135 (1.81)24.3611
2020's38 (0.51)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials645 (7.37%)5.53%
Reviews452 (5.16%)6.00%
Case Studies368 (4.20%)4.05%
Observational0 (0.00%)0.25%
Other7,290 (83.27%)84.16%