Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
| Member | Definition | Class |
|---|
| 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one | A chromone substituted with a phenyl group at position 8 and a morpholine group at position 2. | LY294002 |
| apelin-13 peptide | A 13 amino acid oligopeptide which is the ligand for the apelin receptor (also known as the APJ receptor). It exhibits hypotensive and neuroprotective effects, and may be a potential prognostic biomarker for acute ischemic stroke and multiple sclerosis. | apelin-13 |
| as 1842856 | A quinolone that is 4-quinolone substituted at positions 1, 3, 5, 6 and 7 by ethyl, carboxy, amino, fluorine, and cyclohexylamino groups, respectively. It can directly bind to and block the transcription activity of the active forkhead box protein O1 (Foxo1), but not the Ser256-phosphorylated form. It induces cell death and growth arrest in Burkitt lymphoma cell lines at low concentrations. | AS1842856 |
| bafilomycin a1 | The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus. | bafilomycin A1 |
| chloroquine | An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. | chloroquine |
| elaiophylin | A macrodiolide that is isolated from several bacteria including Streptomyces violaceoniger and other soil actinomycetes. | elaiophylin |
| emetine | A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties. | emetine |
| emetine dihydrochloride | The dihydrochloride salt of emetine. | emetine dihydrochloride |
| salvianolic acid B | A member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza | salvianolic acid B |
| wortmannin | | wortmannin |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 25.2855 | 1 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 2.7987 | 1 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 39.0906 | 1 | 3 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 0.1586 | 7 | 13 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 5.3777 | 2 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 3.7540 | 2 | 4 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 0.0120 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 0.3255 | 2 | 4 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 17.7828 | 2 | 2 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 68.7989 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 30.7314 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 68.7989 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 30.7314 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 0.0962 | 2 | 3 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 28.1838 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 21.5633 | 2 | 3 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 26.6795 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 7.5060 | 2 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 0.2512 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.2406 | 1 | 2 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 0.4140 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 1.6677 | 8 | 16 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 3.4532 | 1 | 2 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 0.1886 | 9 | 15 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 23.7316 | 1 | 5 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 16.7856 | 4 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 6.2734 | 1 | 2 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 46.7508 | 1 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 2 |
| geminin | Homo sapiens (human) | Potency | 3.7123 | 3 | 3 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 0.0088 | 3 | 5 |
| GLS protein | Homo sapiens (human) | Potency | 3.5481 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 5.6580 | 1 | 2 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 0.1674 | 1 | 2 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 0.6188 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 33.9340 | 2 | 5 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 0.9559 | 2 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 2.9020 | 1 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 7.9433 | 2 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 12.9953 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 28.1838 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 2.1414 | 2 | 7 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 0.4072 | 2 | 2 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 37.6858 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 19.6222 | 2 | 2 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 7.0795 | 2 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 58.0479 | 1 | 1 |
| Nrf2 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 17.0659 | 2 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 3.6626 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 0.1000 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 11.3912 | 3 | 6 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| Parkin | Homo sapiens (human) | Potency | 16.8886 | 2 | 3 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 67.4555 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 0.0757 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 11.6747 | 2 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 16.9635 | 1 | 2 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 35.4813 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| PPM1D protein | Homo sapiens (human) | Potency | 2.4542 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 0.0139 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 4.2346 | 2 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 0.4271 | 2 | 4 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 18.3564 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 18.3352 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 0.1437 | 3 | 6 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 0.0110 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 4.1797 | 4 | 6 |
| Smad3 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 6.6769 | 1 | 3 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 1.0000 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 5.5271 | 2 | 12 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 14.0048 | 2 | 5 |
| Thrombopoietin | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 0.0358 | 2 | 4 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 40.0748 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 32.5707 | 2 | 3 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 26.9724 | 1 | 1 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 5.5868 | 1 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 60.4566 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 0.1674 | 1 | 2 |
| Vpr | Human immunodeficiency virus 1 | Potency | 17.7828 | 1 | 1 |
| WRN | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 2.7960 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.7990 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 36.7070 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 23.3590 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 1.0020 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 0.5250 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 1.0020 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 0.5250 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 1.0800 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 0.0380 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 2.1896 | 2 | 2 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 31.6228 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 0.1820 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 5.0130 | 2 | 2 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 9.9000 | 2 | 2 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 6.2350 | 2 | 2 |
| Apelin receptor | Homo sapiens (human) | Ki | 0.0007 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 72.7571 | 7 | 7 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 9.8500 | 2 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 93.8667 | 2 | 6 |
| Bromodomain-containing protein 2 | Homo sapiens (human) | IC50 | 10.3000 | 1 | 1 |
| Bromodomain-containing protein 3 | Homo sapiens (human) | IC50 | 13.7000 | 1 | 1 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | IC50 | 12.4000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 104.0333 | 1 | 3 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 6.9000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 6.9000 | 1 | 1 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 6.9000 | 1 | 1 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 9.6140 | 1 | 1 |
| Chain A, Methyltransferase Wbdd | Escherichia coli | IC50 | 68.0000 | 1 | 1 |
| Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | IC50 | 4.0000 | 1 | 2 |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.1100 | 2 | 2 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 349.9450 | 1 | 1 |
| Dihydrofolate reductase | Bos taurus (cattle) | IC50 | 0.0301 | 2 | 2 |
| Dihydroorotate dehydrogenase | Leishmania major | IC50 | 1,037.0000 | 1 | 2 |
| DNA ligase | Tequatrovirus T4 | IC50 | 823.0000 | 2 | 4 |
| DNA ligase 1 | Homo sapiens (human) | IC50 | 823.0000 | 2 | 4 |
| DNA ligase A | Mycobacterium tuberculosis H37Rv | IC50 | 823.0000 | 2 | 4 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 1.3200 | 11 | 12 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | Ki | 3.6480 | 5 | 5 |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | IC50 | 0.0965 | 2 | 2 |
| Forkhead box protein O1 | Homo sapiens (human) | IC50 | 0.0330 | 1 | 1 |
| Glucose transporter | Leishmania mexicana | IC50 | 0.0810 | 1 | 1 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 67.6667 | 3 | 3 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 8.1000 | 1 | 1 |
| Hexose transporter 1 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0900 | 1 | 1 |
| Histidine-rich protein PFHRP-II | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 396,967.5905 | 13 | 13 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | IC50 | 0.0965 | 2 | 2 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 0.1100 | 2 | 2 |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0085 | 2 | 2 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 150.0000 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 1.6000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 100.0333 | 1 | 3 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 9.1201 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 4.6774 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 3.3113 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 5.7544 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 21.8776 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Gallus gallus (chicken) | IC50 | 0.2600 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | IC50 | 2.3567 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 1.6000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 1.6000 | 1 | 1 |
| P2X purinoceptor 3 | Homo sapiens (human) | IC50 | 0.7550 | 1 | 1 |
| P2Y purinoceptor 12 | Homo sapiens (human) | Ki | 36.4000 | 1 | 1 |
| Phosphatidylinositol 3-kinase regulatory subunit alpha | Homo sapiens (human) | IC50 | 10,501.2652 | 7 | 14 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | IC50 | 0.2800 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | IC50 | 0.4400 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | Homo sapiens (human) | IC50 | 27.0000 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | Homo sapiens (human) | IC50 | 2.1700 | 6 | 12 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Bos taurus (cattle) | IC50 | 3.7533 | 3 | 3 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | IC50 | 2,829.1419 | 37 | 52 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | Ki | 3.0600 | 2 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Mus musculus (house mouse) | IC50 | 0.5000 | 2 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | IC50 | 3,870.1808 | 24 | 38 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | IC50 | 5,446.1616 | 19 | 27 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 3,678.4861 | 23 | 40 |
| Phosphoethanolamine N-methyltransferase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 554.0000 | 1 | 1 |
| Phosphoinositide 3-kinase regulatory subunit 5 | Homo sapiens (human) | IC50 | 0.8695 | 1 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 2.5030 | 4 | 4 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 5.3311 | 2 | 2 |
| Procathepsin L | Homo sapiens (human) | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 8.2500 | 2 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 5.4700 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 1.5000 | 1 | 1 |
| Serine hydrolase RBBP9 | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| Serine-protein kinase ATM | Homo sapiens (human) | IC50 | 70.0000 | 3 | 3 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | IC50 | 70.0000 | 3 | 3 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 3.9820 | 12 | 12 |
| Serine/threonine-protein kinase mTOR | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 3.3640 | 5 | 5 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | IC50 | 1.4000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 1.0860 | 3 | 5 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Ki | 10.7667 | 1 | 9 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Ki | 10.7667 | 1 | 9 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | IC50 | 18.2634 | 3 | 5 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Ki | 10.7667 | 1 | 9 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Ki | 10.7667 | 1 | 9 |
| Sigma intracellular receptor 2 | Homo sapiens (human) | Ki | 0.5012 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.0794 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 2.3000 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 6.0000 | 1 | 1 |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | IC50 | 0.1080 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 5.4700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome coronavirus 2 | IC50 | 3.5800 | 2 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 5.4700 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 5.4700 | 1 | 1 |
| Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | IC50 | 0.5000 | 1 | 1 |
| V-type proton ATPase subunit S1 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Vacuolar proton pump subunit B | Gallus gallus (chicken) | IC50 | 0.0300 | 1 | 1 |