A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
| Member | Definition | Class |
|---|
| 7-hydroxycoumarin | A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7. | umbelliferone |
| beta-tocopherol | A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts. | beta-tocopherol |
| chlorogenic acid | A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 3-hydroxy group of quinic acid. It is an intermediate metabolite in the biosynthesis of lignin. | chlorogenic acid |
| elaidic acid | A 9-octadecenoic acid and the trans-isomer of oleic acid. | elaidic acid |
| gallocatechol | A flavan-3,3',4',5,5',7-hexol having (2R,3R)-configuration. | (-)-epigallocatechin |
| myricetin | A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants. | myricetin |
| pentadecanoic acid | A straight-chain saturated fatty acid containing fifteen-carbon atoms. | pentadecanoic acid |
| piperine | A N-acylpiperidine that is piperidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum. | piperine |
| stachydrine | An amino acid betaine that is L-proline zwitterion in which both of the hydrogens attached to the nitrogen are replaced by methyl groups. | L-proline betaine |
| theobromine | A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator. | theobromine |
| trans-4-coumaric acid | The trans-isomer of 4-coumaric acid. | trans-4-coumaric acid |
| trigonelline | An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group. | N-methylnicotinate |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 14.9131 | 1 | 5 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 2.2029 | 1 | 3 |
| 67.9K protein | Vaccinia virus | Potency | 12.5893 | 1 | 2 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 18.6089 | 1 | 5 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 35.4813 | 2 | 2 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 20.3510 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 13.3010 | 7 | 15 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 4.1740 | 3 | 5 |
| arylsulfatase A | Homo sapiens (human) | Potency | 12.0095 | 1 | 2 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 10.9479 | 2 | 2 |
| Ataxin-2 | Homo sapiens (human) | Potency | 14.8436 | 2 | 3 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 8.8108 | 4 | 5 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 11.8237 | 2 | 3 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 23.9341 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 13.5110 | 2 | 5 |
| BRCA1 | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 68.7291 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 11.9613 | 1 | 5 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 2.1648 | 2 | 5 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 31.6534 | 1 | 3 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 24.4413 | 2 | 5 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 39.8107 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 10.7890 | 2 | 8 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 10.6654 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 1.2718 | 3 | 7 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 17.0619 | 1 | 4 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 10.2227 | 1 | 5 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 10.7890 | 2 | 8 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 41.1749 | 2 | 6 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 11.3112 | 1 | 3 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 10.8631 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 10.6840 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 37.9083 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 15.5804 | 2 | 11 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 11.9877 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 1.3522 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 16.4816 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 6.9241 | 1 | 2 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 0.1995 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 1.2204 | 2 | 3 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 15.0030 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 19.4003 | 2 | 7 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 1.1884 | 2 | 9 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 13.6226 | 8 | 14 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 61.2549 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 10.0437 | 6 | 12 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 7.4840 | 1 | 8 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 23.9566 | 4 | 6 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 51.5795 | 2 | 3 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 14.0720 | 3 | 8 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 33.1734 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 10.6840 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 15.3311 | 1 | 6 |
| geminin | Homo sapiens (human) | Potency | 11.9302 | 2 | 2 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 2.2886 | 3 | 5 |
| GLS protein | Homo sapiens (human) | Potency | 17.6655 | 2 | 5 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 31.0378 | 1 | 3 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 3.2583 | 2 | 3 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 7.1196 | 2 | 15 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 9.3852 | 2 | 4 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 63.3756 | 2 | 4 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 10.6840 | 1 | 1 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 35.7250 | 2 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 1.9953 | 2 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 3.6626 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 112.2020 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 10.6840 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 0.3982 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 10.6840 | 1 | 1 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 7.1369 | 1 | 3 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 0.2984 | 2 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 29.8435 | 3 | 6 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 7.3732 | 1 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 10.2179 | 2 | 4 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 19.9073 | 1 | 2 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.0112 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 27.4041 | 3 | 5 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 5.6234 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 7.9328 | 3 | 7 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 42.6703 | 2 | 3 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 48.8311 | 3 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 31.0176 | 3 | 3 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 2.0585 | 3 | 3 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 1.4831 | 1 | 3 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 5.5610 | 1 | 2 |
| polyprotein | Zika virus | Potency | 33.1734 | 1 | 1 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 1.5044 | 1 | 3 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 16.6491 | 2 | 3 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 57.8620 | 1 | 2 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 1.9953 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 23.7358 | 1 | 2 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 24.3616 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 5.0150 | 2 | 4 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 10.3882 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 3.0975 | 3 | 6 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 30.4646 | 3 | 5 |
| RGS12 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 19.8812 | 2 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 9.4662 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 112.2020 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 35.4813 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 28.8453 | 2 | 11 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 21.6794 | 1 | 2 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 32.0624 | 3 | 10 |
| Thrombopoietin | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 62.2781 | 2 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 47.4953 | 2 | 3 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 6.3534 | 2 | 3 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 5.5610 | 1 | 2 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 5.5610 | 1 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 36.6814 | 1 | 4 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 1.3476 | 1 | 2 |
| Vpr | Human immunodeficiency virus 1 | Potency | 63.0957 | 1 | 1 |
| WRN | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | IC50 | 1.5000 | 1 | 1 |
| 1,3-beta-D-glucan synthase catalytic subunit | Candida albicans | IC50 | 90.0000 | 1 | 1 |
| 2-5A-dependent ribonuclease | Homo sapiens (human) | IC50 | 264.0000 | 1 | 1 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 14.0000 | 1 | 1 |
| 6-phosphogluconate dehydrogenase, decarboxylating | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 140.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 14,550.0000 | 2 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 37.8000 | 1 | 1 |
| Acetylcholinesterase | Bos taurus (cattle) | IC50 | 233.0000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 31.8625 | 4 | 4 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 152.3820 | 4 | 5 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | Ki | 250.0000 | 2 | 3 |
| ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | Homo sapiens (human) | IC50 | 24.8000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 26.0000 | 4 | 5 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 15.4750 | 2 | 2 |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | IC50 | 35.4500 | 1 | 2 |
| Aldo-keto reductase family 1 member C21 | Mus musculus (house mouse) | IC50 | 12.3000 | 1 | 1 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 33.2000 | 1 | 1 |
| Alpha-amylase 1A | Homo sapiens (human) | IC50 | 30.2000 | 2 | 2 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | IC50 | 90.8000 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 8.0400 | 2 | 3 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 58.9800 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Mus musculus (house mouse) | Ki | 19.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 0.7665 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Mus musculus (house mouse) | Ki | 3.1900 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 20.2875 | 8 | 8 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Anthrax toxin receptor 2 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 2 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Arginase | Leishmania amazonensis | IC50 | 2.1000 | 1 | 1 |
| Arginase | Leishmania amazonensis | Ki | 1.2000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 44.8000 | 2 | 2 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 3.9800 | 1 | 1 |
| Beta-carbonic anhydrase 1 | Mycobacterium tuberculosis H37Rv | Ki | 1.7300 | 1 | 3 |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 2.0000 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 168.9933 | 3 | 3 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 22.0000 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Ki | 35.7000 | 1 | 1 |
| Cannabinoid receptor 2 | Homo sapiens (human) | Ki | 361.3000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 31,000.0000 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 212.6587 | 6 | 8 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 3.5138 | 5 | 5 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 10.1000 | 2 | 2 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 6.6800 | 2 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 31,000.0000 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 228.2475 | 6 | 8 |
| Carbonic anhydrase 2 | Mycobacterium tuberculosis H37Rv | Ki | 1.7300 | 1 | 3 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 7.5700 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 9.6000 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 5.9600 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 7.7600 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 6.7200 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 5.2300 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 1.3590 | 5 | 5 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 0.9400 | 3 | 3 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 0.9000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 0.9400 | 3 | 3 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 0.9400 | 3 | 3 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 10.2000 | 1 | 1 |
| Chain A, Pancreatic alpha-amylase | Homo sapiens (human) | Ki | 110.0000 | 1 | 2 |
| Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | IC50 | 0.7800 | 1 | 4 |
| Cholinesterase | Equus caballus (horse) | IC50 | 500.0000 | 1 | 1 |
| Cystathionine beta-synthase | Homo sapiens (human) | IC50 | 18.8000 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 0.3700 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.0270 | 2 | 2 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 23.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase | Leishmania major | IC50 | 257.4300 | 1 | 4 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | IC50 | 0.8800 | 1 | 1 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | Ki | 0.7100 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3A isoform a | Homo sapiens (human) | IC50 | 17.5000 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 2.3900 | 1 | 1 |
| DNA primase TraC | Escherichia coli | IC50 | 700.0000 | 1 | 1 |
| DNA repair protein RAD52 homolog | Homo sapiens (human) | IC50 | 2.9800 | 5 | 5 |
| DNA topoisomerase 1 | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| DNA-(apurinic or apyrimidinic site) endonuclease | Homo sapiens (human) | IC50 | 0.3200 | 2 | 2 |
| ELAV-like protein 3 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Escherichia coli K-12 | IC50 | 100.0000 | 1 | 1 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 3.7000 | 2 | 2 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 1.9225 | 3 | 3 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 3,000.0000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | Ki | 1,000.0000 | 2 | 2 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 2.1200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Bos taurus (cattle) | Ki | 0.0130 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Bos taurus (cattle) | Ki | 0.0130 | 1 | 1 |
| Genome polyprotein | Hepatitis C virus (isolate BK) | IC50 | 36.6000 | 1 | 1 |
| Genome polyprotein | Zika virus | IC50 | 11.6500 | 2 | 2 |
| Genome polyprotein | Zika virus | Ki | 0.8000 | 1 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | Saccharomyces cerevisiae S288C | IC50 | 1,000.0000 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | IC50 | 616.5950 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | Trypanosoma cruzi | IC50 | 616.5800 | 1 | 1 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | IC50 | 13.5000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 11 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 3 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 4 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 5 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 6 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 7 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Histone deacetylase 9 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Hydroxycarboxylic acid receptor 2 | Homo sapiens (human) | Ki | 14.0000 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | IC50 | 21.0400 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | Ki | 3.8100 | 1 | 1 |
| Inositol hexakisphosphate kinase 2 | Homo sapiens (human) | IC50 | 0.7000 | 1 | 1 |
| Inositol polyphosphate multikinase | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | Ki | 2.6000 | 1 | 1 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 36.9400 | 8 | 10 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 0.9489 | 2 | 2 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 2.9200 | 1 | 1 |
| intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 12.5000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | IC50 | 1.5000 | 3 | 3 |
| large T antigen | Betapolyomavirus macacae | IC50 | 16.7800 | 1 | 2 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 0.9489 | 2 | 2 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 2.1000 | 2 | 2 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 1.9400 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 1.9400 | 1 | 2 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 157.0000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | Ki | 7.8500 | 2 | 2 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Ki | 1.7000 | 1 | 1 |
| NAD kinase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 68.0667 | 3 | 3 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 3.2600 | 2 | 2 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 258.3333 | 3 | 3 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | Ki | 0.1350 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 1,364.9500 | 4 | 4 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 54.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 500.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 500.0000 | 1 | 1 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 407.3333 | 3 | 3 |
| Protein E6 | Human papillomavirus 16 | IC50 | 0.8500 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 1.6900 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 10.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 13.3667 | 2 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 39.4800 | 1 | 1 |
| Ribonuclease HI | Escherichia coli K-12 | IC50 | 20.0000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 43.0000 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 1.5620 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 0.7800 | 2 | 2 |
| Short transient receptor potential channel 5 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 150.0000 | 1 | 1 |
| Small conductance calcium-activated potassium channel protein 3 | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Solute carrier family 2, facilitated glucose transporter member 2 | Homo sapiens (human) | IC50 | 12.0000 | 2 | 2 |
| Solute carrier family 2, facilitated glucose transporter member 4 | Rattus norvegicus (Norway rat) | Ki | 33.5000 | 1 | 1 |
| Sorbitol dehydrogenase | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| Substance-K receptor | Cavia porcellus (domestic guinea pig) | IC50 | 82.6000 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 82.6000 | 1 | 1 |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | IC50 | 100.5000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 106.7500 | 4 | 4 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 6.4000 | 1 | 1 |
| Tyrosine-protein kinase transforming protein Fps | Fujinami sarcoma virus | Ki | 1.8000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 59.8667 | 3 | 3 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Ki | 4,107.5500 | 2 | 2 |
| Tyrosine-protein phosphatase non-receptor type 2 | Homo sapiens (human) | IC50 | 77.9000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | IC50 | 6.8000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 112.7933 | 2 | 3 |
| Zn finger protein | Nicotiana tabacum (common tobacco) | Ki | 0.7540 | 1 | 1 |