Substance intended to kill parasitic worms (helminths).
| Member | Definition | Class |
|---|
| albendazole | A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a propylsulfanyl group at position 5. It is commonly used in the treatment of parasitic worm infestations. | albendazole |
| benomyl | A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. | benomyl |
| bisbenzimidazole | | pibenzimol |
| costunolide | A germacranolide with anthelminthic, antiparasitic and antiviral activities. | costunolide |
| dichlorvos | An alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate. | dichlorvos |
| dithiazanine | A cationic C3-cyanine dye with 3-ethylbenzothiazol-2-yl groups at both ends. | dithiazanine |
| dithiazanine iodide | | dithiazanine iodide |
| famophos | | famphur |
| gentian violet | An organic chloride salt that is the monochloride salt of crystal violet cation. It has been used in creams for the topical treatment of bacterial and fungal infections, being effective against some Gram-positive bacteria (notably Staphylococcus species) and some pathogenic fungi (including Candida species) but use declined following reports of animal carcinogenicity. It has also been used for dying wood, silk, and paper, as well as a histological stain. | crystal violet |
| monepantel | A secondary carboxamide resulting from the formal condensation of the carboxy group of p-[(trifluoromethyl)sulfanyl]benzoic acid with the amino group of (2S)-2-amino-3-hydroxy-2-methylpropanenitrile in which the hydroxy group has been converted to the corresponding 5-cyano-2-(trifluoromethyl)phenyl ether. A broad-spectrum nematicide, it is used to control gastrointestinal roundworms in sheep and goats. | monepantel |
| naftalofos | | naftalofos |
| niclosamide | A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections. | niclosamide |
| paromomycin | An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. | paromomycin |
| piperazine | An azacycloalkane that consists of a six-membered ring containing two nitrogen atoms at opposite positions. | piperazine |
| piperazine adipate | A piperazinium salt obtained by combining equimolar amounts of piperazine and adipic acid. | piperazine adipate |
| pyrvinium | A quinolinium ion that is 1-methylquinolinium substituted by dimethylamino group at position 6 and a (E)-2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl at position 2. It is a anthelminthic drug active against pinworms. The salts of pyrvinium can also be used as anticancer agents. | pyrvinium |
| trichlorfon | A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group. | trichlorfon |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 4.7360 | 1 | 2 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 4.0716 | 2 | 7 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 40.3374 | 4 | 29 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 23.0008 | 1 | 9 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 26.2701 | 1 | 7 |
| alpha synuclein, partial | Homo sapiens (human) | Potency | 0.1515 | 1 | 1 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 1.4137 | 1 | 3 |
| AR protein | Homo sapiens (human) | Potency | 12.4929 | 10 | 76 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 9.6511 | 3 | 17 |
| arylsulfatase A | Homo sapiens (human) | Potency | 37.9330 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 8.2025 | 5 | 7 |
| Ataxin-2 | Homo sapiens (human) | Potency | 14.4838 | 1 | 9 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 20.4900 | 2 | 2 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 12.0360 | 2 | 12 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 0.9528 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 1.3092 | 1 | 1 |
| beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa] | Homo sapiens (human) | Potency | 0.1500 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 23.4788 | 2 | 4 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 13.7177 | 1 | 6 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 7.3942 | 1 | 3 |
| caspase-3 | Homo sapiens (human) | Potency | 13.7177 | 1 | 6 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 7.3942 | 1 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 18.9892 | 3 | 27 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 6.0604 | 2 | 11 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 31.0990 | 1 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 26.9875 | 1 | 3 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 54.2839 | 2 | 4 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 24.2524 | 2 | 4 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 32.7517 | 2 | 3 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 15.1421 | 1 | 3 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 15.8114 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 5.4993 | 1 | 5 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| chaperonin-containing TCP-1 beta subunit homolog | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 0.3981 | 1 | 1 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 1.5714 | 1 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 5.0536 | 1 | 3 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 8.2703 | 1 | 2 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 9.5620 | 2 | 12 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 13.9132 | 2 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 23.2096 | 1 | 12 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 0.3445 | 2 | 2 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 2.0749 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 1.0610 | 1 | 2 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 11.2202 | 1 | 1 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 18.9375 | 12 | 103 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 36.4372 | 2 | 9 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 16.0118 | 10 | 75 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 20.0804 | 1 | 6 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 8.9734 | 4 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 22.0914 | 5 | 27 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | Potency | 44.6684 | 1 | 1 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 4.2284 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 2.4979 | 1 | 3 |
| G | Vesicular stomatitis virus | Potency | 5.0536 | 1 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| GALC protein | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 9.5620 | 1 | 6 |
| geminin | Homo sapiens (human) | Potency | 3.6910 | 4 | 15 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 11.7933 | 3 | 21 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 2.5455 | 2 | 3 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 18.2490 | 6 | 7 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 18.3430 | 5 | 22 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 20.2411 | 1 | 12 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 1.9953 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 1.8493 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 21.4584 | 2 | 20 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 8.1108 | 2 | 12 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 11.1948 | 2 | 18 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 39.4992 | 2 | 10 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 5.0536 | 1 | 3 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 5.9501 | 1 | 3 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 19.9526 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 34.8241 | 2 | 13 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 4.9727 | 3 | 5 |
| IDH1 | Homo sapiens (human) | Potency | 1.2130 | 1 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 5.0536 | 1 | 6 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 16.9244 | 1 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 7.0861 | 1 | 5 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 7.0861 | 1 | 5 |
| Interferon beta | Homo sapiens (human) | Potency | 6.3996 | 2 | 5 |
| interleukin 8 | Homo sapiens (human) | Potency | 45.0879 | 1 | 3 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 4.9088 | 2 | 11 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 3.5841 | 1 | 3 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | Potency | 0.1800 | 1 | 1 |
| Leukotriene B4 receptor 2 | Homo sapiens (human) | Potency | 0.1800 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 13.7543 | 4 | 17 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 7.5060 | 1 | 2 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 10.1538 | 3 | 8 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 10.9828 | 2 | 6 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 3.5406 | 2 | 2 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 15.3548 | 1 | 3 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 16.5311 | 1 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 2.3350 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 0.1289 | 1 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 22.9952 | 4 | 29 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 2.9093 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 21.4540 | 1 | 4 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 25.5401 | 1 | 10 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 24.4630 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 7.6791 | 2 | 12 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 4.4965 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 23.5258 | 3 | 38 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 3.1623 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 0.7667 | 1 | 1 |
| Parkin | Homo sapiens (human) | Potency | 1.6326 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 10.5999 | 2 | 8 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 0.3793 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 22.1823 | 5 | 25 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 24.1969 | 5 | 20 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 34.1790 | 1 | 3 |
| PINK1 | Homo sapiens (human) | Potency | 1.6326 | 1 | 2 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 1.7811 | 1 | 2 |
| polyprotein | Zika virus | Potency | 2.4979 | 1 | 3 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 31.6228 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 14.6501 | 1 | 3 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 11.2947 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 27.1884 | 3 | 16 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 23.9416 | 1 | 5 |
| progesterone receptor | Homo sapiens (human) | Potency | 24.5314 | 2 | 13 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 12.4496 | 4 | 4 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 25.1189 | 2 | 2 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 3.1623 | 2 | 2 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 7.5797 | 2 | 12 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 0.1652 | 1 | 3 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 16.8336 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 19.8019 | 3 | 36 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 11.1786 | 4 | 29 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 1.6208 | 2 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 29.0615 | 2 | 12 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 29.0615 | 2 | 12 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 3.6578 | 2 | 4 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 6.1886 | 1 | 8 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 2.8497 | 2 | 20 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 50.1187 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 0.0053 | 1 | 1 |
| Thrombopoietin | Homo sapiens (human) | Potency | 0.1000 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 7.9975 | 3 | 23 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 26.3530 | 4 | 11 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 25.1914 | 7 | 29 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 7.3660 | 1 | 3 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| TSHR protein | Homo sapiens (human) | Potency | 92.5374 | 2 | 3 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 42.1632 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 16.1936 | 2 | 2 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 1.7811 | 1 | 2 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 1.7811 | 1 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 32.8580 | 1 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 22.6343 | 2 | 11 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 17.5769 | 5 | 19 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 50.2888 | 1 | 3 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 20.2411 | 1 | 12 |