Pericoronitis

Synonym
Pericoronitis

Excerpt	Reference
"Acute pericoronitis is a common oral infection characterised by a predominance of anaerobic micro-organisms such as peptococci, peptostreptococci, bacteroides and fusobacteria, and also spirochaetes."	( Gill, Y; Scully, C, 1991)
"Pericoronitis is a common disease in the eruption phase of third molars, sometimes debilitating, with an impact on the quality of life."	( Braz-Silva, PH; Bussadori, SK; Horliana, ACRT; Jorge, WA; Longo, PL; Mayer, MPA; Michel-Crosato, E; Negreiros, RM; Palmieri, M; Pavani, C; Schalch, TO; Tortamano, IP, 2019)
"Pericoronitis is a common disease that impacts the quality of life of individuals during the eruption of the third molars."	( Bussadori, SK; Horliana, ACRT; Motta, LJ; Pavani, C; Piatto, ÉT; Schalch, TO; Simão, DS, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	27 (40.30)	23.3326
1990's	10 (14.93)	12.5806
2000's	9 (13.43)	18.1394
2010's	19 (28.36)	28.8240
2020's	2 (2.99)	9.53

Drug	Relationship Strength	Studies	Trials
choline	low	1	0
dimethyl sulfoxide	low	1	0
iodine	low	1	0
urea	low	1	0
phenytoin	low	2	0
acetaminophen	medium	3	1
aspirin	low	1	0
cefuroxime	medium	1	1
chlordiazepoxide	low	1	0
diclofenac	low	1	0
flurbiprofen	low	1	0
lidocaine	medium	1	1
metronidazole	medium	9	3
phenylbutazone	low	1	0
prilocaine	medium	1	1
procaine	low	1	0
tinidazole	low	1	0
tosufloxacin	medium	1	1
prednisolone	low	1	0
hydroxyproline	low	1	0
prednisone	low	1	0
penicillin g	medium	1	1
cloxacillin	low	1	0
methylene blue	medium	2	1
oxacillin	low	1	0
ampicillin	low	3	0
penicillin v	medium	4	2
framycetin	low	1	0
dextropropoxyphene	low	1	0
azomycin	low	1	0
benzydamine	low	1	0
erythromycin	low	2	0
scandium	medium	1	1
chromium	medium	1	1
erbium	medium	1	1
yttrium	medium	1	1
fluorides	low	1	0
triamcinolone	low	1	0
carticaine	medium	1	1
amoxicillin	low	8	0
cefmetazole	low	1	0
cefaclor anhydrous	medium	1	1
cephalosporin c	low	1	0
lenampicillin	low	2	0
fluorodeoxyglucose f18	low	1	0
oxazolidin-2-one	low	1	0
fibrinogen	medium	2	1
naproxen	low	1	0
fibrin	medium	1	1
inositol 3-phosphate	low	2	0
linezolid	low	1	0
clindamycin	low	4	0
zithromax	medium	1	1
cystine	low	1	0
alpha-chymotrypsin	medium	2	1
dinoprostone	low	1	0
7432 s	low	1	0
codeine	medium	1	1
gallium	medium	1	1
chlorhexidine	medium	2	2
amoxicillin-potassium clavulanate combination	low	1	0
indocyanine green	medium	1	1
n-monoacetylcystine	low	1	0
jaw	medium	2	1
tetracycline	low	4	0
minocycline	low	1	0
salicylates	low	1	0
warfarin	low	1	0
transforming growth factor beta	low	1	0
cefuroxime axetil	medium	1	1
technetium tc 99m medronate	medium	2	1

Protein Targets (719)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	9	0	0	9
aryl hydrocarbon receptor	7	0	0	7
Solute carrier family 15 member 1	0	13	0	13
Solute carrier family 15 member 1	0	4	0	5
Solute carrier family 15 member 2	0	9	0	9
Solute carrier family 15 member 2	0	9	0	10
RAR-related orphan receptor gamma	10	0	0	10
ATAD5 protein, partial	4	0	0	4
GLS protein	8	0	0	8
Microtubule-associated protein tau	7	0	0	7
Smad3	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	12	0	0	12
thyroid stimulating hormone receptor	9	0	0	9
nuclear receptor subfamily 1, group I, member 3	7	0	0	7
progesterone receptor	8	0	0	8
EWS/FLI fusion protein	10	0	0	10
retinoic acid nuclear receptor alpha variant 1	16	0	0	16
retinoid X nuclear receptor alpha	9	0	0	9
estrogen-related nuclear receptor alpha	17	0	0	17
estrogen nuclear receptor alpha	22	0	0	22
peroxisome proliferator activated receptor gamma	8	0	0	8
chromobox protein homolog 1	12	0	0	12
thyroid hormone receptor beta isoform 2	10	0	0	10
peripheral myelin protein 22	5	0	0	5
cytochrome P450 3A4 isoform 1	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	6	3	0	9
ATP-binding cassette sub-family C member 3	0	15	0	15
Multidrug resistance-associated protein 4	0	15	0	16
Solute carrier family 22 member 6	0	6	0	6
Carbonic anhydrase 12	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	3
Bile salt export pump	0	3	0	3
Voltage-dependent calcium channel gamma-2 subunit	5	0	0	5
Bile salt export pump	0	23	0	23
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	7	0	7
Carbonic anhydrase 2	0	7	0	7
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	1	0	3
Prostaglandin G/H synthase 1	0	7	0	7
Carbonic anhydrase 3	0	1	0	1
Cytochrome P450 3A4	0	5	1	7
Cytochrome P450 2D6	0	3	0	4
Cytochrome P450 2C9	0	13	0	15
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	6	3	0	9
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	6	3	0	9
Gamma-aminobutyric acid receptor subunit gamma-2	6	3	0	9
UDP-glucuronosyltransferase 1-6	0	2	0	3
Glutamate receptor 2	5	0	0	5
Gamma-aminobutyric acid receptor subunit alpha-5	6	3	0	9
Gamma-aminobutyric acid receptor subunit alpha-3	6	3	0	9
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	2	0	3
Carbonic anhydrase 4	0	3	0	3
Prostaglandin G/H synthase 1	0	7	0	7
Carbonic anhydrase 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	6	3	0	9
Gamma-aminobutyric acid receptor subunit alpha-2	6	3	0	9
Gamma-aminobutyric acid receptor subunit alpha-4	6	3	0	9
Gamma-aminobutyric acid receptor subunit gamma-3	6	3	0	9
Gamma-aminobutyric acid receptor subunit alpha-6	6	3	0	9
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Prostaglandin G/H synthase 2	0	7	0	8
Carbonic anhydrase 7	0	1	0	1
Nuclear receptor ROR-gamma	5	0	0	5
Cytochrome P450 2J2	0	9	0	9
Gamma-aminobutyric acid receptor subunit alpha-1	6	4	0	10
Gamma-aminobutyric acid receptor subunit beta-3	6	3	0	9
Gamma-aminobutyric acid receptor subunit beta-2	6	3	0	9
Carbonic anhydrase 9	0	3	0	3
GABA theta subunit	6	3	0	9
Canalicular multispecific organic anion transporter 1	0	15	0	15
Carbonic anhydrase 15	0	2	0	2
Carbonic anhydrase 13	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	6	3	0	9
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
toxin B	0	0	0	1
Chain A, Beta-lactamase	6	0	0	6
Chain A, 2-oxoglutarate Oxygenase	8	0	0	8
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
AR protein	16	0	0	16
apical membrane antigen 1, AMA1	2	0	0	2
Beta-lactamase	0	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	9	0	0	9
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
DNA polymerase kappa isoform 1	5	0	0	5
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase	0	0	0	2
Kappa-type opioid receptor	0	0	0	2
B2 metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Cruzipain	3	0	0	3
Beta-lactamase	0	0	0	2
acid sphingomyelinase	3	0	0	3
GLI family zinc finger 3	15	0	0	15
farnesoid X nuclear receptor	5	0	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
euchromatic histone-lysine N-methyltransferase 2	14	0	0	14
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
DNA polymerase beta	2	0	0	2
geminin	15	0	0	15
60 kDa heat shock protein, mitochondrial	0	2	0	2
Beta-lactamase OXA-7	0	0	0	4
Spike glycoprotein	4	0	0	4
10 kDa heat shock protein, mitochondrial	0	2	0	2
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Thiosulfate sulfurtransferase	0	2	0	2
Metallo-beta-lactamase VIM-13	0	0	0	2
Efflux transporter	0	1	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	1	0	3
Class D beta-lactamase	0	0	0	3
60 kDa chaperonin	0	2	0	2
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	2	0	2
Metallo-b-lactamase	0	0	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	3
Beta-lactamase VIM-1	0	0	0	2
ATP-dependent phosphofructokinase	5	0	0	5
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	6	0	0	6
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	6	0	0	6
Chain B, HADH2 protein	6	0	0	6
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	3	0	0	3
thioredoxin reductase	7	0	0	7
hypothetical protein, conserved	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	6	0	0	6
glucocorticoid receptor [Homo sapiens]	11	0	0	11
cytochrome P450 2D6	4	0	0	4
glucocerebrosidase	2	0	0	2
peroxisome proliferator-activated receptor delta	5	0	0	5
Rac1 protein	0	0	1	1
IDH1	6	0	0	6
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Bloom syndrome protein isoform 1	5	0	0	5
muscarinic acetylcholine receptor M1	5	0	0	5
lethal factor (plasmid)	3	0	0	3
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Fatty acid-binding protein, liver	0	4	0	4
Integrin beta-3	1	1	0	2
Myeloperoxidase	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	1	1	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A2a	0	2	0	2
Substance-P receptor	0	1	0	1
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
cytochrome P450 2D6 isoform 1	3	0	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Guanylate cyclase soluble subunit beta-2	0	0	1	1
Guanylate cyclase soluble subunit alpha-2	0	0	1	1
Histamine H2 receptor	4	0	0	4
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
phosphopantetheinyl transferase	5	0	0	5
TDP1 protein	18	0	0	18
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
vitamin D3 receptor isoform VDRA	7	0	0	7
importin subunit beta-1 isoform 1	2	0	0	2
serine/threonine-protein kinase PLK1	2	0	0	2
snurportin-1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	3	0	0	3
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
streptokinase A precursor	0	0	7	7
Estrogen receptor	0	0	2	2
Estrogen receptor beta	0	0	2	2
Solute carrier family 22 member 8	0	3	0	5
Solute carrier family 22 member 8	0	5	0	6
Insulin-degrading enzyme	0	1	0	1
mitogen-activated protein kinase 1	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	12	0	0	12
Interferon beta	11	0	0	11
Solute carrier family 22 member 8	0	2	0	3
glp-1 receptor, partial	6	0	0	6
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
Cellular tumor antigen p53	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Histamine H1 receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
Luciferase	7	0	0	7
acetylcholinesterase	3	0	0	3
PAX8	0	0	0	1
15-lipoxygenase, partial	1	0	0	1
pregnane X receptor	3	0	0	3
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
SMAD family member 2	6	0	0	6
USP1 protein, partial	3	0	0	3
SMAD family member 3	6	0	0	6
caspase 7, apoptosis-related cysteine protease	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
PINK1	1	0	0	1
estrogen receptor 2 (ER beta)	4	0	0	4
pregnane X nuclear receptor	13	0	0	13
G	5	0	0	5
67.9K protein	1	0	0	1
Parkin	2	0	0	2
vitamin D (1,25- dihydroxyvitamin D3) receptor	6	0	0	6
heat shock protein 90	0	0	1	1
caspase-3	4	0	0	4
calcineurin A1, putative	0	0	1	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	7	0	0	7
thyroid stimulating hormone receptor	4	0	0	4
activating transcription factor 6	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
Histone H2A.x	5	0	0	5
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
cytochrome P450 2C19 precursor	1	0	0	1
cytochrome P450 2C9 precursor	3	0	0	3
perilipin-5	0	1	0	1
thyroid hormone receptor beta isoform a	5	0	0	5
perilipin-1	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
transcriptional regulator ERG isoform 3	2	0	0	2
heat shock protein beta-1	3	0	0	3
huntingtin isoform 2	2	0	0	2
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
flap endonuclease 1	6	0	0	6
protein AF-9 isoform a	0	0	0	2
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	2
bcl-2-related protein A1	0	1	0	1
nuclear receptor ROR-gamma isoform 1	4	0	0	4
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
lamin isoform A-delta10	10	0	0	10
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	1	0	3
Solute carrier family 22 member 1	0	2	0	4
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	4
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
72 kDa type IV collagenase	0	2	0	2
Matrix metalloproteinase-9	0	2	0	2
Trypanothione reductase	0	1	0	1
Alpha-synuclein	2	1	0	3
TAR DNA-binding protein 43	7	0	0	7
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Inositol hexakisphosphate kinase 1	5	0	0	5
Multidrug and toxin extrusion protein 1	0	4	0	4
ATPase family AAA domain-containing protein 5	4	0	0	4
Ataxin-2	4	0	0	4
Spermine oxidase	0	1	0	1
cytochrome P450 2C9, partial	5	0	0	5
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	1	0	2
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Protein-arginine deiminase type-4	0	5	0	5
Beta-lactamase	0	1	0	2
Beta-lactamase TEM	0	2	0	3
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	4
Delta-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	1	3
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	5	0	5
Cytochrome P450 2D4	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
Aldo-keto reductase family 1 member B10	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Transthyretin	0	0	1	3
Albumin	0	2	5	7
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin G/H synthase 2	0	3	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Solute carrier family 22 member 6	0	3	0	4
Prostaglandin G/H synthase 1	0	4	0	5
Carbonic anhydrase 4	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	2	0	2
regulator of G-protein signaling 4	3	0	0	3
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
30S ribosomal protein S6	0	5	1	6
30S ribosomal protein S7	0	5	1	6
50S ribosomal protein L15	0	5	1	6
ATP-dependent translocase ABCB1	0	2	0	2
ATP-dependent translocase ABCB1	0	2	0	2
60 kDa chaperonin	0	1	0	1
50S ribosomal protein L10	0	5	1	6
50S ribosomal protein L11	0	5	1	6
50S ribosomal protein L7/L12	0	5	1	6
50S ribosomal protein L19	0	5	1	6
50S ribosomal protein L1	0	5	1	6
50S ribosomal protein L20	0	5	1	6
50S ribosomal protein L27	0	5	1	6
50S ribosomal protein L28	0	5	1	6
50S ribosomal protein L29	0	5	1	6
50S ribosomal protein L31	0	5	1	6
50S ribosomal protein L31 type B	0	5	1	6
50S ribosomal protein L32	0	5	1	6
50S ribosomal protein L33	0	5	1	6
50S ribosomal protein L34	0	5	1	6
50S ribosomal protein L35	0	5	1	6
50S ribosomal protein L36	0	5	1	6
30S ribosomal protein S10	0	5	1	6
30S ribosomal protein S11	0	5	1	6
30S ribosomal protein S12	0	5	1	6
30S ribosomal protein S13	0	5	1	6
30S ribosomal protein S16	0	5	1	6
30S ribosomal protein S18	0	5	1	6
30S ribosomal protein S19	0	5	1	6
30S ribosomal protein S20	0	5	1	6
30S ribosomal protein S2	0	5	1	6
30S ribosomal protein S3	0	5	1	6
30S ribosomal protein S4	0	5	1	6
30S ribosomal protein S5	0	5	1	6
30S ribosomal protein S8	0	5	1	6
30S ribosomal protein S9	0	5	1	6
50S ribosomal protein L13	0	5	1	6
50S ribosomal protein L14	0	5	1	6
50S ribosomal protein L16	0	5	1	6
50S ribosomal protein L23	0	5	1	6
30S ribosomal protein S15	0	5	1	6
50S ribosomal protein L17	0	5	1	6
50S ribosomal protein L21	0	5	1	6
50S ribosomal protein L30	0	5	1	6
50S ribosomal protein L6	0	5	1	6
30S ribosomal protein S14	0	5	1	6
30S ribosomal protein S17	0	5	1	6
30S ribosomal protein S1	0	5	1	6
50S ribosomal protein L18	0	5	1	6
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	5	1	6
50S ribosomal protein L3	0	5	1	6
50S ribosomal protein L24	0	5	1	6
50S ribosomal protein L4	0	5	1	6
50S ribosomal protein L22	0	5	1	6
50S ribosomal protein L5	0	5	1	6
30S ribosomal protein S21	0	5	1	6
50S ribosomal protein L25	0	5	1	6
Cytochrome P450 1B1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
50S ribosomal protein L36 2	0	5	1	6
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Carbonic anhydrase	0	1	0	1
PPM1D protein	4	0	0	4
histone deacetylase 9 isoform 3	3	0	0	3
Acid-sensing ion channel 3	0	1	0	1
Amyloid-beta precursor protein	0	2	0	2
Aldo-keto reductase family 1 member C4	0	2	0	2
Aldo-keto reductase family 1 member C3	0	2	0	2
Aldo-keto reductase family 1 member C2	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Aldo-keto reductase family 1 member C1	0	2	0	2
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Amino acid transporter	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	3
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
DNA gyrase subunit A	0	2	0	3
DNA gyrase subunit B	0	2	0	3
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	3	0	3
Amine oxidase [flavin-containing] B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Cytochrome P450 2C19	0	1	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Renin	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, Ferritin light chain	2	0	0	2
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
Fumarate hydratase	1	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
thioredoxin glutathione reductase	3	0	0	3
isocitrate dehydrogenase 1, partial	1	0	0	1
polyprotein	1	0	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Vpr	2	0	0	2
survival motor neuron protein isoform d	3	0	0	3
muscleblind-like protein 1 isoform 1	5	0	0	5
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
neuropeptide S receptor isoform A	2	0	0	2
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Albumin	0	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Alpha-1B adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Sodium-dependent noradrenaline transporter	0	0	1	1
Cruzipain	0	1	0	1
Alpha-1A adrenergic receptor	0	2	0	2
Guanine nucleotide-binding protein G	2	0	0	2
Inositol monophosphatase 1	2	0	0	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	3
Hormone-sensitive lipase	0	1	0	1
Caspase-1	0	1	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
arylsulfatase A	4	0	0	4
STE24	0	0	0	1
Trypsin	0	0	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	1	0	2
MecA	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Replicase polyprotein 1ab	0	1	0	1
Estrogen receptor 1	0	1	0	1
nonstructural protein 1	2	0	0	2
D(1A) dopamine receptor	1	0	0	1
fMet-Leu-Phe receptor	0	1	0	1
M-phase phosphoprotein 8	1	0	0	1
Cyclooxygenase-2	0	1	0	1
Gamma-aminobutyric acid	0	1	0	1
endonuclease IV	1	0	0	1
peripheral myelin protein 22 isoform 1	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
luciferase	0	0	0	1
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	6	2	13
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	6	0	6
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Androgen receptor	0	1	0	1
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
GALC protein	1	0	0	1
ClpP	1	0	0	1
NFKB1 protein, partial	1	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (67)

Protein Targets (719)

Pericoronitis

Synonyms(1)

Research Excerpts

Overview

Research

Studies (67)

Drugs Studied (75)

Protein Targets (719)