A molecular entity that is an electron-pair acceptor and therefore able to form a covalent bond with an electron-pair donor (Lewis base), thereby producing a Lewis adduct.
ChEBI ID: 39143
| Member | Definition | Class |
|---|---|---|
| aluminum chloride | aluminium trichloride | |
| antimony pentafluoride | antimony pentafluoride | |
| antimony trichloride | An inorganic chloride salt with formula SbCl3. It is used as a reagent for detecting vitamin A and related carotenoids, reacting with the carotenoid to form a blue complex that can be measured by colorimetry (the Carr-Price test). Solutions of antimony trichloride were formerly used for dissolving and removing horn stubs from calves and goats. | antimony trichloride |
| ferric chloride | iron trichloride | |
| zinc chloride | A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions. | zinc dichloride |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 569 (13.17) | 18.7374 |
| 1990's | 732 (16.95) | 18.2507 |
| 2000's | 1,189 (27.53) | 29.6817 |
| 2010's | 1,540 (35.66) | 24.3611 |
| 2020's | 289 (6.69) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 89 (1.95%) | 5.53% |
| Reviews | 53 (1.16%) | 6.00% |
| Case Studies | 111 (2.44%) | 4.05% |
| Observational | 2 (0.04%) | 0.25% |
| Other | 4,303 (94.41%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| AR protein | Homo sapiens (human) | Potency | 24.0500 | 4 | 4 |
| Ataxin-2 | Homo sapiens (human) | Potency | 13.6854 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 13.6854 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 40.1089 | 2 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 14.0769 | 7 | 7 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 54.4827 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 15.0245 | 6 | 6 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 54.9410 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 55.7461 | 3 | 3 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 39.7411 | 2 | 2 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 7.6959 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 18.9486 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 50.4772 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 48.9662 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 4.1984 | 2 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 43.6412 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 27.3060 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 10.9622 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 4.8966 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 27.3060 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 5.3457 | 2 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 47.5966 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 32.5964 | 2 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 47.6790 | 2 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 7.6959 | 1 | 1 |