molecular adaptor activity

Definition

Target type: molecularfunction

The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. [GOC:mtg_MIT_16mar07, GOC:vw]

Molecular adaptor activity refers to the ability of a protein or other molecule to mediate interactions between two or more other molecules, often by bringing them into close proximity. These adaptors can function by binding to multiple partners simultaneously, thereby facilitating the formation of protein complexes or signaling pathways. They play a crucial role in regulating a wide range of cellular processes, including signal transduction, protein trafficking, and cytoskeletal organization. For instance, adaptors can bring together kinases and their substrates, enabling phosphorylation events that trigger downstream signaling cascades. Alternatively, they can link transmembrane receptors to intracellular signaling molecules, relaying extracellular signals into the cell. Furthermore, adaptors can facilitate the recruitment of specific proteins to particular cellular compartments, such as the nucleus or the plasma membrane, thereby ensuring the correct localization and function of these molecules. In essence, molecular adaptors act as molecular bridges, connecting different cellular components and orchestrating complex cellular processes.'
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Proteins (28)

Compounds (1,733)