A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
| Member | Definition | Class |
|---|
| 2-anisidine | A substituted aniline that is aniline in which the hydrogen ortho to the amino group has been replaced by a methoxy group. It is used as a chemical intermediate in the synthesis of azo pigments and dyes. | o-anisidine |
| 2,4-dinitrophenylhydrazine | A C-nitro compound that is phenylhydrazine substituted at the 2- and 4-positions by nitro groups. | 2,4-dinitrophenylhydrazine |
| 4-anisidine | A substituted aniline that is aniline in which the hydrogen para to the amino group has been replaced by a methoxy group. It is used as a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils. | p-anisidine |
| 4-phenylenediamine | A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus. | 1,4-phenylenediamine |
| acetic anhydride | An acyclic carboxylic anhydride derived from acetic acid. | acetic anhydride |
| bentiromide | The dipeptide obtained by condensation of N-benzoyl-L-tyrosine with 4-aminobenzoic acid. Used as a noninvasive screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy, it is given by mouth: the amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas. | bentiromide |
| bnps-skatole | A bromoindole that is 3H-indole in which the hydrogen at position 2 has been replaced by an (o-nitrophenyl)sulfanyl group and in which the hydrogens at position 3 have been replaced by a bromine and a methyl group. It is used particularly for the selective cleavage of tryptophanyl peptide bonds (cleavage occurs at peptide bonds after amino acids with available C(gamma)=C(delta) double bonds such as tryptophan, tyrosine, and histidine). | BNPS-skatole |
| bromodichloromethane | A halomethane that is dichloromethane in which oneof the hydrogens has been replaced by a bromine atom. It occurs as a contaminant in drinking water. | bromodichloromethane |
| bromosuccinimide | A five-membered cyclic dicarboximide compound having a bromo substituent on the nitrogen atom. | N-bromosuccinimide |
| carbamide peroxide | A mixture obtained by combining equimolar amounts of hydrogen peroxide and urea. | urea hydrogen peroxide |
| methyl carbonate | A carbonate ester that is carbonic acid in which both hydrogens are replaced by methyl groups. A flammable, colourless liquid (m.p. 2-4degreeC, b.p. 90degreeC) with a characterstic ester-like odour, it is used as a 'green' methylating agent and as a solvent. | dimethyl carbonate |
| nitric acid | A nitrogen oxoacid of formula HNO3 in which the nitrogen atom is bonded to a hydroxy group and by equivalent bonds to the remaining two oxygen atoms. | nitric acid |
| phenylisothiocyanate | An isothiocyanate having a phenyl group attached to the nitrogen; used for amino acid sequencing in the Edman degradation. | phenyl isothiocyanate |
| piperidine | An azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine. | piperidine |
| platinum tetrachloride | A platinum coordination entity consisting of platinum(II) bound to two chlorine atoms. | platinum dichloride |
| sodium tungstate(vi) | An inorganic sodium salt having tungstate as the counterion. Combines with hydrogen peroxide for the oxidation of secondary amines to nitrones. | sodium tungstate |
| thiobarbituric acid | A barbiturate, the structure of which is that of barbituric acid in which the oxygen at C-2 is replaced by sulfur. | 2-thiobarbituric acid |
| triethylenediamine | An organic heterobicylic compound that is piperazine with an ethane-1,2-diyl group forming a bridge between N1 and N4. It is typically used as a catalyst in polymerization reactions. | triethylenediamine |
| trifluoroacetic acid | A monocarboxylic acid that is the trifluoro derivative of acetic acid. | trifluoroacetic acid |
| trimethylenediamine | An alkane-alpha,omega-diamine comprising a propane skeleton with amino substituents at positions 1 and 3. | trimethylenediamine |
| trinitrobenzenesulfonic acid | The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions. | 2,4,6-trinitrobenzenesulfonic acid |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 41.1147 | 2 | 5 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 36.4261 | 1 | 2 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 14.1254 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 37.4070 | 6 | 12 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 42.0272 | 2 | 11 |
| Ataxin-2 | Homo sapiens (human) | Potency | 55.7692 | 1 | 3 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 53.7440 | 2 | 5 |
| C-terminal-binding protein 1 | Homo sapiens (human) | Potency | 13.4614 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 31.6439 | 1 | 4 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 22.8952 | 1 | 2 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 4.9171 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 56.2341 | 1 | 2 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 15.4871 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 3.0901 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 0.7852 | 2 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 52.2694 | 1 | 3 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 0.1259 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 37.7542 | 6 | 16 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 4.8755 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 36.4483 | 6 | 23 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 19.0148 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 21.3839 | 2 | 3 |
| G | Vesicular stomatitis virus | Potency | 15.4871 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 38.2695 | 2 | 10 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 9.2933 | 2 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 61.3793 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 63.6261 | 1 | 1 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 57.9939 | 2 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 62.4454 | 2 | 9 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 15.4871 | 1 | 1 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 10.0000 | 1 | 1 |
| IDH1 | Homo sapiens (human) | Potency | 6.5131 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 15.4871 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 15.4871 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 49.2672 | 2 | 6 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 14.9872 | 2 | 2 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 0.0063 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 20.5033 | 3 | 10 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 2.3710 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 35.7196 | 3 | 15 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 2.8695 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 23.2876 | 2 | 2 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 47.1460 | 2 | 7 |
| progesterone receptor | Homo sapiens (human) | Potency | 37.4308 | 2 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 21.8085 | 2 | 13 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 40.1281 | 3 | 20 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 44.3863 | 2 | 3 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 10.6213 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 21.8528 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 67.5396 | 2 | 7 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 39.5214 | 4 | 7 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 34.6770 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 29.3644 | 2 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 28.4556 | 1 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 61.3793 | 1 | 1 |
| Vpr | Human immunodeficiency virus 1 | Potency | 56.2341 | 1 | 1 |