Page last updated: 2024-09-27

Ophthalmia, Sympathetic

Granulomatous uveitis which follows in one eye after a penetrating injury to the other eye; the secondarily affected eye is called the sympathizing eye, and the injured eye is called the exciting or activating eye.

Synonyms(1)

Synonym
Ophthalmia, Sympathetic

Research Excerpts

Overview

ExcerptReference
"Sympathetic ophthalmia is a rare bilateral panuveitis that follows penetrating injury to one eye."( Hakin, KN; Lightman, SL; Pearson, RV, 1992)
"Sympathetic ophthalmia is a bilateral diffuse granulomatous panuveitis occurring after accidental or surgical penetrating injury to one eye."( Charles, NC, 1987)
"Sympathetic ophthalmia is a rare form of autoimmune uveitis and manifests in 90% of cases within the first year after penetrating injuries or surgical interventions."( Frühauf, A; Hellmund, K; Naumann, GO; Seiler, T, 1998)
"Sympathetic ophthalmia is a rare and potentially visually devastating bilateral panuveitis, typically following non-surgical penetrating injury to one eye."( Buttery, R; Cairns, J; Hall, A; Vote, BJ, 2004)
"Sympathetic ophthalmia is a rare, bilateral inflammation of the uveal tract following penetrating trauma or surgery in one eye."( Agrawal, R; Biswas, J; Gupta, V; Invernizzi, A; Mahajan, S; Rao, NA, 2017)
"Sympathetic ophthalmia is a severe sight-threatening disorder that can lead to blindness if not diagnosed and managed appropriately."( Banerjee, M; Kumar, V; Patil, VS; Surve, A, 2021)

Context

ExcerptReference
"Seventeen cases of sympathetic ophthalmia have been followed up for as long as 23 years (average 10."( Azar, A; Makley, TA, 1978)

Research

Studies (182)

TimeframeStudies, This Condition (%)All Conditions %
pre-199097 (53.30)23.3326
1990's20 (10.99)12.5806
2000's23 (12.64)18.1394
2010's31 (17.03)28.8240
2020's11 (6.04)9.53
DrugIndicatedRelationship StrengthStudiesTrials
aspirin0low10
azathioprine0low150
chlorambucil0low100
chloroquine0low10
diclofenac0low10
erythrosine0low20
lidocaine0low10
indomethacin0low20
isoniazid0low20
2-propanol0low190
ketorolac0low10
aminosalicylic acid0low10
procaine0low10
pyrimethamine0low10
sulfanilamide0low10
gatifloxacin0low10
thioridazine0low10
thymidine0low10
spironolactone0low10
aldosterone0low10
chloramphenicol0low10
kanamycin a0low10
tyrosine0low10
fluocinolone acetonide0low30
ampicillin0low10
triamcinolone acetonide0low100
methylprednisolone0low100
acrolein0low10
betamethasone0low10
helium0low10
trolamine salicylate0low10
bromocriptine0low10
phenyl acetate0low10
triamcinolone0low10
propiconazole0low110
2-methoxyestradiol0low10
methotrexate0low90
atropine0low50
cortisone0low130
3-nitrotyrosine0low10
n-acetylneuraminic acid0low10
mycophenolic acid0low30
mercaptopurine0low30
thioguanine anhydrous0low10
lincomycin0low10
alpha-chymotrypsin0low10
arsenic0low10
sulfur0low10
indocyanine green0low70
scopolamine hydrobromide0low10
cytochrome c-t0low10
tetracycline0low10
chlortetracycline0low10
ferric ammonium citrate0low10
cyclosporine0low200
muramidase0low10
eye0low330
phosphorus radioisotopes0low10

Protein Targets (799)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Beta-lactamase7007
glp-1 receptor, partial6006
thioredoxin reductase130013
ATAD5 protein, partial7007
GLS protein110011
PPM1D protein5005
TDP1 protein220022
regulator of G-protein signaling 45005
estrogen-related nuclear receptor alpha240024
glucocerebrosidase3003
IDH1140014
euchromatic histone-lysine N-methyltransferase 2230023
lysosomal alpha-glucosidase preproprotein1001
interferon gamma precursor0001
chromobox protein homolog 1130013
nuclear factor erythroid 2-related factor 2 isoform 2130013
atrial natriuretic peptide receptor 2 precursor2002
serine/threonine-protein kinase mTOR isoform 14004
urokinase-type plasminogen activator precursor7007
plasminogen precursor7007
urokinase plasminogen activator surface receptor precursor7007
geminin190019
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
lamin isoform A-delta10120012
Interferon beta160016
Tubulin alpha-1A chain0101
Tubulin beta chain0101
Sex hormone-binding globulin0033
Cytochrome P450 1A10101
TAR DNA-binding protein 436006
Cytochrome P450 1B10101
Tubulin beta-2B chain0101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
ATP-dependent phosphofructokinase9009
hypoxia-inducible factor 1 alpha subunit6006
RAR-related orphan receptor gamma190019
GLI family zinc finger 3230023
AR protein320032
aldehyde dehydrogenase 1 family, member A1140014
retinoic acid nuclear receptor alpha variant 1210021
retinoid X nuclear receptor alpha170017
estrogen nuclear receptor alpha300030
peroxisome proliferator-activated receptor delta130013
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a210021
activating transcription factor 68008
v-jun sarcoma virus 17 oncogene homolog (avian)100010
Histone H2A.x120012
thyroid hormone receptor beta isoform a7007
heat shock protein beta-18008
nuclear factor erythroid 2-related factor 2 isoform 1200020
Voltage-dependent calcium channel gamma-2 subunit140014
Glutamate receptor 2141015
Chain A, Putative fructose-1,6-bisphosphate aldolase5005
Chain A, JmjC domain-containing histone demethylation protein 3A3003
phosphopantetheinyl transferase7007
bromodomain adjacent to zinc finger domain 2B7007
pyruvate kinase PKM isoform a1001
Glycoprotein hormones alpha chain1001
Guanine nucleotide-binding protein G4004
Tubulin--tyrosine ligase0202
Free fatty acid receptor 30011
Free fatty acid receptor 20112
Tyrosine-protein kinase Lck0011
Tyrosine-protein kinase Fyn0112
Fibrinogen C domain-containing protein 10101
thyroid stimulating hormone receptor5005
peroxisome proliferator activated receptor gamma140014
Transient receptor potential cation channel subfamily A member 10022
glucocorticoid receptor [Homo sapiens]240024
Corticosteroid-binding globulin0303
Mineralocorticoid receptor 0539
Androgen receptor0809
Mineralocorticoid receptor0101
Solute carrier organic anion transporter family member 1A10001
Chain A, 2-oxoglutarate Oxygenase110011
Microtubule-associated protein tau7007
thioredoxin glutathione reductase7007
Smad36006
microphthalmia-associated transcription factor isoform 90101
Carbonic anhydrase 109011
Carbonic anhydrase 209213
Tyrosine-protein phosphatase non-receptor type 10123
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE120012
Chain A, Mutant Al2 6e7p9g0011
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Cruzipain3003
Beta-lactamase 0001
acid sphingomyelinase2002
apical membrane antigen 1, AMA13003
farnesoid X nuclear receptor150015
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 17007
thyroid hormone receptor beta isoform 2160016
DNA polymerase beta3003
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)100010
DNA polymerase kappa isoform 15005
60 kDa heat shock protein, mitochondrial0101
Beta-lactamase OXA-70001
Solute carrier family 15 member 10202
Solute carrier family 15 member 10101
Spike glycoprotein91111
10 kDa heat shock protein, mitochondrial0101
Angiopoietin-1 receptor0011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Thiosulfate sulfurtransferase0101
Metallo-beta-lactamase VIM-130001
Efflux transporter 0001
Beta-lactamase 0001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Class D beta-lactamase0001
60 kDa chaperonin 0101
Metallo-beta-lactamase0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
10 kDa chaperonin 0101
Metallo-b-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase VIM-1 0001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE100010
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 85005
hypothetical protein, conserved3003
cytochrome P450 family 3 subfamily A polypeptide 4130013
EWS/FLI fusion protein140014
cytochrome P450 2D69009
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Bloom syndrome protein isoform 16006
muscarinic acetylcholine receptor M16006
lethal factor (plasmid)3003
Prostaglandin-H2 D-isomerase0202
ATP-binding cassette sub-family C member 3017017
Multidrug resistance-associated protein 4017018
Solute carrier family 22 member 60202
Prostaglandin G/H synthase 1 0304
Prostaglandin G/H synthase 2 0203
Bile salt export pump024024
Epidermal growth factor receptor0303
Fatty acid-binding protein, liver0404
Integrin beta-34105
Myeloperoxidase0202
Prostaglandin G/H synthase 10405
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb4105
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10707
Adenosine receptor A10203
Adenosine receptor A2a0203
Substance-P receptor0202
Prostaglandin G/H synthase 20718
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma6006
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-17209
Prostaglandin G/H synthase 20404
Rho-associated protein kinase 20202
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Canalicular multispecific organic anion transporter 1016016
Sigma non-opioid intracellular receptor 10314
Sigma non-opioid intracellular receptor 10112
nuclear receptor subfamily 1, group I, member 3140014
pregnane X nuclear receptor200020
cystic fibrosis transmembrane conductance regulator0101
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0202
5-hydroxytryptamine receptor 40606
Muscarinic acetylcholine receptor M207111
Muscarinic acetylcholine receptor M407110
Muscarinic acetylcholine receptor M10518
Muscarinic acetylcholine receptor M30417
Muscarinic acetylcholine receptor M40417
Muscarinic acetylcholine receptor M50417
Muscarinic acetylcholine receptor M50619
Muscarinic acetylcholine receptor M205210
Muscarinic acetylcholine receptor M107111
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M30619
Alpha-1D adrenergic receptor0606
5-hydroxytryptamine receptor 2C0617
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor2003
5-hydroxytryptamine receptor 70101
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0112
Chain A, Ferritin light chain3003
acetylcholinesterase6006
SMAD family member 2100010
Fumarate hydratase7007
SMAD family member 3100010
G9009
polyprotein7007
P531001
arylsulfatase A3003
aryl hydrocarbon receptor120012
thyroid stimulating hormone receptor6006
peripheral myelin protein 22 isoform 15005
hemoglobin subunit beta3003
cellular tumor antigen p53 isoform a5005
peripheral myelin protein 227007
survival motor neuron protein isoform d8008
cytochrome P450 3A4 isoform 17007
M-phase phosphoprotein 85005
muscleblind-like protein 1 isoform 15005
Gamma-aminobutyric acid receptor subunit pi7108
Bile salt export pump0303
HLA class I histocompatibility antigen, B alpha chain 9009
Cellular tumor antigen p53200020
Gamma-aminobutyric acid receptor subunit beta-17108
Gamma-aminobutyric acid receptor subunit delta7108
Gamma-aminobutyric acid receptor subunit gamma-27108
Gamma-aminobutyric acid receptor subunit alpha-57108
Gamma-aminobutyric acid receptor subunit alpha-37108
Gamma-aminobutyric acid receptor subunit gamma-17108
Gamma-aminobutyric acid receptor subunit alpha-27108
Gamma-aminobutyric acid receptor subunit alpha-47108
Gamma-aminobutyric acid receptor subunit gamma-37108
Gamma-aminobutyric acid receptor subunit alpha-67108
Gamma-aminobutyric acid receptor subunit beta-37108
Gamma-aminobutyric acid receptor subunit beta-27108
GABA theta subunit7108
Inositol hexakisphosphate kinase 19009
ATPase family AAA domain-containing protein 5150015
Ataxin-2170017
Gamma-aminobutyric acid receptor subunit epsilon7108
Protein-arginine deiminase type-40505
cytochrome P450 2C9, partial9009
pregnane X receptor6006
progesterone receptor170017
vitamin D (1,25- dihydroxyvitamin D3) receptor170017
nuclear receptor subfamily 1, group I, member 26006
galanin receptor type 30101
Glucocorticoid receptor018326
Glycine receptor subunit alpha-1018018
Glycine receptor subunit beta018018
Glycine receptor subunit alpha-2018018
Glycine receptor subunit alpha-3018018
ORF730011
Genome polyprotein 0224
dopamine D1 receptor3003
D(1A) dopamine receptor2002
vitamin D3 receptor isoform VDRA8008
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10303
Beta-1 adrenergic receptor0202
Cytochrome P450 3A40707
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0505
D(2) dopamine receptor0415
Alpha-2B adrenergic receptor0505
Alpha-2C adrenergic receptor0505
D0202
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 1A0404
Alpha-2B adrenergic receptor0202
ATP-dependent translocase ABCB10101
D(1A) dopamine receptor0404
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
D(1B) dopamine receptor0202
5-hydroxytryptamine receptor 2A0415
5-hydroxytryptamine receptor 1B0404
D(4) dopamine receptor0202
D(3) dopamine receptor0404
Alpha-synuclein1203
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60404
D(2) dopamine receptor0314
L-ornithine N(5)-monooxygenase0112
Telomerase reverse transcriptase0101
Ubiquitin carboxyl-terminal hydrolase 20101
Ubiquitin carboxyl-terminal hydrolase isozyme L10101
Replicase polyprotein 1ab0314
Replicase polyprotein 1ab0516
Indoleamine 2,3-dioxygenase 10101
Ubiquitin carboxyl-terminal hydrolase isozyme L30101
Tyrosine-protein phosphatase non-receptor type 20101
Nuclear receptor subfamily 4 group A member 10011
Receptor-type tyrosine-protein phosphatase epsilon0101
Tyrosine-protein phosphatase non-receptor type 60101
Tyrosine-protein phosphatase non-receptor type 70101
Tryptophan 2,3-dioxygenase0101
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN0101
Heat shock factor protein 10011
Tyrosine-protein phosphatase non-receptor type 110101
Receptor-type tyrosine-protein phosphatase eta0101
Hypoxia-inducible factor 1-alpha0101
Regulator of G-protein signaling 170101
Ubiquitin carboxyl-terminal hydrolase 150101
Ubiquitin carboxyl-terminal hydrolase isozyme L50101
Luciferase7007
NFKB1 protein, partial2002
GALC protein3003
Thrombopoietin1001
caspase 7, apoptosis-related cysteine protease2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)8008
caspase-32002
potassium voltage-gated channel subfamily H member 2 isoform d4004
FAD-linked sulfhydryl oxidase ALR0001
Carbonic anhydrase 120203
Cytochrome P450 2D60202
Carbonic anhydrase 90405
Solute carrier organic anion transporter family member 1B30405
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
streptokinase A precursor0033
Dihydroxyacetone phosphate acyltransferase0002
30S ribosomal protein S60202
30S ribosomal protein S70202
50S ribosomal protein L150202
50S ribosomal protein L100202
50S ribosomal protein L110202
50S ribosomal protein L7/L120202
50S ribosomal protein L190202
50S ribosomal protein L10202
50S ribosomal protein L200202
50S ribosomal protein L270202
50S ribosomal protein L280202
50S ribosomal protein L290202
50S ribosomal protein L310202
50S ribosomal protein L31 type B0202
50S ribosomal protein L320202
50S ribosomal protein L330202
50S ribosomal protein L340202
50S ribosomal protein L350202
50S ribosomal protein L360202
30S ribosomal protein S100202
30S ribosomal protein S110202
30S ribosomal protein S120202
30S ribosomal protein S130202
30S ribosomal protein S160202
30S ribosomal protein S180202
30S ribosomal protein S190202
30S ribosomal protein S200202
30S ribosomal protein S20202
30S ribosomal protein S30202
30S ribosomal protein S40202
30S ribosomal protein S50202
30S ribosomal protein S80202
30S ribosomal protein S90202
50S ribosomal protein L130202
50S ribosomal protein L140202
50S ribosomal protein L160202
50S ribosomal protein L230202
30S ribosomal protein S150202
50S ribosomal protein L170202
50S ribosomal protein L210202
50S ribosomal protein L300202
50S ribosomal protein L60202
30S ribosomal protein S140202
30S ribosomal protein S170202
30S ribosomal protein S10202
50S ribosomal protein L180202
50S ribosomal protein L20202
50S ribosomal protein L30202
50S ribosomal protein L240202
50S ribosomal protein L40202
50S ribosomal protein L220202
50S ribosomal protein L50202
30S ribosomal protein S210202
50S ribosomal protein L250202
50S ribosomal protein L36 20202
Methionine--tRNA ligase, mitochondrial0011
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0112
Replicase polyprotein 1ab0112
glucose-6-phosphate 1-dehydrogenase isoform b0101
flap endonuclease 15005
Transmembrane protease serine 20112
Dihydrofolate reductase 0303
DNA ligase0101
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0101
Histidine-rich protein PFHRP-II0102
Procathepsin L0213
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Spike glycoprotein0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
DNA ligase 10101
Serine/threonine-protein kinase mTOR0101
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 20707
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Angiotensin-converting enzyme 2 0112
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120202
endonuclease IV2002
atrial natriuretic peptide receptor 1 precursor2002
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10505
Aldo-keto reductase family 1 member B100101
UDP-glucuronosyltransferase 1A90103
Dihydrofolate reductase0506
Cytochrome c oxidase subunit 20202
Transthyretin0013
Albumin0437
Interleukin-80202
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Cytochrome P450 2C9 0405
Fatty acid-binding protein, intestinal0213
Aldo-keto reductase family 1 member B10202
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60202
UDP-glucuronosyltransferase 1A1 0203
UDP-glucuronosyltransferase 1A40101
Sodium- and chloride-dependent GABA transporter 10202
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Prostaglandin G/H synthase 2 0202
UDP-glucuronosyltransferase 1A30001
UDP-glucuronosyltransferase 2B10 0101
Sodium- and chloride-dependent betaine transporter0202
Cytochrome P450 2J20303
Prostaglandin G/H synthase 20203
Solute carrier family 22 member 60203
Prostaglandin G/H synthase 1 0202
Carbonic anhydrase 40202
P2Y purinoceptor 120202
UDP-glucuronosyltransferase 1A70102
UDP-glucuronosyltransferase 1A100102
chaperonin-containing TCP-1 beta subunit homolog1001
thyrotropin-releasing hormone receptor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
eyes absent homolog 2 isoform a1001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
histone acetyltransferase KAT2A isoform 15005
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0101
mitogen-activated protein kinase 12002
15-lipoxygenase, partial2002
DNA gyrase subunit B0001
DNA gyrase subunit A0202
DNA gyrase subunit B0202
DNA topoisomerase 4 subunit B0001
DNA topoisomerase 4 subunit A0102
DNA topoisomerase 2-alpha0001
DNA gyrase subunit A0001
DNA gyrase subunit A0202
Chain A, membrane-associated prostaglandin E synthase-20101
estrogen receptor 2 (ER beta)9009
67.9K protein7007
Parkin2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
cytochrome P450 2D6 isoform 14004
cytochrome P450 2C9 precursor1001
ras-related protein Rab-9A3003
nuclear receptor ROR-gamma isoform 15005
neuropeptide S receptor isoform A1001
Prostaglandin E synthase0101
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Phospholipase A2, major isoenzyme0101
Neuronal acetylcholine receptor subunit alpha-40101
Androgen receptor0426
Neuronal acetylcholine receptor subunit beta-20101
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Sodium-dependent dopamine transporter0202
Thromboxane-A synthase 0101
Serum paraoxonase/arylesterase 10202
Indoleamine 2,3-dioxygenase 10101
Caspase-10102
Nitric oxide synthase, inducible0101
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0102
Bifunctional epoxide hydrolase 20101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0022
Aldo-keto reductase family 1 member C30202
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30102
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Uracil nucleotide/cysteinyl leukotriene receptor0101
Solute carrier family 22 member 70001
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Solute carrier family 22 member 80103
Dehydrogenase/reductase SDR family member 90101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10202
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
N-glycosylase/DNA lyase0101
Polyphenol oxidase 20102
Cytochrome P450 1A20202
Formamidopyrimidine-DNA glycosylase0101
Cytochrome P450 2C80101
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Cytochrome P450 2C190303
Endonuclease III-like protein 10101
DNA gyrase subunit B0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0102
Pantothenate synthetase0101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
NPC intracellular cholesterol transporter 1 precursor2002
Caspase-30101
Caspase-40101
Caspase-50101
Caspase-90101
Cell division control protein 42 homolog0101
Ras-related C3 botulinum toxin substrate 10101
Serine/threonine-protein kinase PAK 10101
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0101
transcriptional regulator ERG isoform 34004
UDP-glucose 6-dehydrogenase0101
Solute carrier family 22 member 80001
Hypoxanthine-guanine phosphoribosyltransferase0002
UDP-glucose 6-dehydrogenase0101
Purine nucleoside phosphorylase0011
UDP-glucuronosyltransferase 1A1 0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP1001
USP1 protein, partial3003
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
importin subunit beta-1 isoform 11001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
snurportin-11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0203
5-hydroxytryptamine receptor 2C0304
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0438
Glucose-6-phosphate 1-dehydrogenase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0303
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0404
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Pteridine reductase 10202
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0202
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110002
Broad substrate specificity ATP-binding cassette transporter ABCG20102
nonstructural protein 12002
Nuclear receptor subfamily 1 group I member 20011
Nuclear receptor subfamily 1 group I member 20011
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Inosine-5'-monophosphate dehydrogenase 20202
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
Sodium-dependent serotonin transporter0202
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A80001
Sialidase-40101
Sialidase-10101
Sialidase-30101
Sialidase-20101
luciferase0001
Estrogen receptor0415
Progesterone receptor0416
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0314
heat shock protein HSP 90-alpha isoform 20102
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
heat shock protein 90, putative0001
dual specificity protein phosphatase 30101
low molecular weight phosphotyrosine protein phosphatase isoform c0101
tyrosine-protein phosphatase non-receptor type 22 isoform 10101
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 10101
Estrogen receptor0011
Beta-hexosaminidase subunit alpha0102
Beta-hexosaminidase subunit beta0101
Substance-K receptor0101
Dihydrofolate reductase0101
Low molecular weight phosphotyrosine protein phosphatase0101
Dipeptidyl peptidase 40101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trace amine-associated receptor 50011
Estrogen receptor beta0011
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Multidrug and toxin extrusion protein 10101
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Vpr1001
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 20112
Cholinesterase0101
Carbonic anhydrase 30102
Acetylcholinesterase0101
Carbonic anhydrase 40102
Carbonic anhydrase 60203
Carbonic anhydrase 5A, mitochondrial0101
5-hydroxytryptamine receptor 2B0202
Delta-type opioid receptor0101
Carbonic anhydrase 5A, mitochondrial0204
Carbonic anhydrase0102
Carbonic anhydrase 70102
Carbonic anhydrase0102
Disintegrin and metalloproteinase domain-containing protein 171001
Carbonic anhydrase 0101
Mu-type opioid receptor0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0102
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Carbonic anhydrase 0102
Carbonic anhydrase 130101
Carbonic anhydrase 150102
Carbonic anhydrase 130101
Protein argonaute-20011
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0103
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
Stromelysin-10101
Multidrug transporter MdfA0101
Alpha-1B adrenergic receptor0404
Neutrophil collagenase0101
Alpha-1D adrenergic receptor0202
Alpha-1A adrenergic receptor0404
Collagenase 30101
Cannabinoid receptor 10101
Integrase 0101
Solute carrier family 22 member 70001
PAX80001
Adenosine receptor A30202
Apoptosis regulator Bcl-20101
Polyunsaturated fatty acid lipoxygenase ALOX150101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Mitogen-activated protein kinase 3 0101
Xanthine dehydrogenase/oxidase0101
Bcl-2-like protein 10101
Snq2p0001
Caspase-71001
caspase-31001
huntingtin isoform 21001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Albumin0011
Aldo-keto reductase family 1 member B10202
Tryptophan 5-hydroxylase 10101
Angiotensin-converting enzyme0202
D(4) dopamine receptor0202
Sodium-dependent noradrenaline transporter 0202
Histamine H2 receptor0202
Histamine H1 receptor0101
Sodium-dependent serotonin transporter0202
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 70101
Histamine H1 receptor0202
Kappa-type opioid receptor0202
Proteasome subunit alpha type-60011
Cathepsin D 0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Sodium-dependent dopamine transporter 0202
Aldehyde oxidase0002
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Nuclear receptor subfamily 3 group C member 3 0202
Mucosa-associated lymphoid tissue lymphoma translocation protein 10101
Thymidine kinase 0102
Thymidine kinase, cytosolic0204
Thymidine kinase0102
Thymidine phosphorylase0001
Polyunsaturated fatty acid 5-lipoxygenase0101
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase, cytosolic 0002
Thymidine kinase0001
Thymidylate kinase0101
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Thymidine kinase0001
procathepsin L isoform 1 preproprotein0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Plasma kallikrein0001
Glutamate receptor ionotropic, NMDA 1 0001
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Carbonic anhydrase-like protein, putative0001
Glutamate receptor ionotropic, NMDA 2D0001
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Taste receptor type 2 member 140001
Glutamate receptor ionotropic, NMDA 3A0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]