Aurora kinase inhibitor

Any protein kinase inhibitor that inhibits the action of an Aurora kinase (a group of serine/threonine kinases that are essential for cell proliferation).

ChEBI ID: 70770

Members (7)

Member	Definition	Class
2-(4-morpholinoanilino)-6-cyclohexylaminopurine	A member of the class of purines that is 9H-purine in which the hydrogens at positions 2 and 6 are replaced by a [4-(morpholin-4-yl)phenyl]nitrilo group and a cyclohexylamino group, respectively.	reversine
azd 1152	A dihydrogen phosphate prodrug of a pyrazoloquinazoline aurora kinase inhibitor AZD1152-hydroxyquinazoline pyrazol anilide(HQPA) and is converted rapidly to the active AZD1152-HQPA in plasma.	AZT-1152
azd 1152-hqpa	A member of the of quinazolines that is 4-aminoquinazolin-7-ol in which the amino group at position 4 has been substituted by a 5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl group, while the hydroxy group at position 7 has been converted into the corresponding 3-[ethyl(2-hydroxyethyl)aminopropyl ether.	AZD-1152
jadomycin b	A jadomycin that is jadomycin A in which the phenolic hydroxy group at position 12 has been converted to the corresponding 2,6-dideoxy-alpha-L-ribo-hexopyranoside, isolated from Streptomyces venezuelae. It exists as a diastereoisomeric mixture consisting of both 3aS and 3aR isomers.	jadomycin B
quercetin	A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.	quercetin
SU6656	A member of the class of oxindoles that is 3-methyleneoxindole in which the hydrogeh at position 5 has been replaced by a dimethylaminosulfonyl group and in which one of the hydrogens of the methylene group has been replaced by a 4,5,6,7-tetrahydro-indol-2-yl group. It is a specific inhibitor of Src family kinase.	SU6656
zm 447439	A member of the class of quinazolines that is quinazoline which is substituted at positions 4, 6 and 7 by a (4-benzamidophenyl)nitrilo group, methoxy group and a 3-(morpholin-4-yl)propoxy group, respectively. It is an ATP-competitive inhibitor of Aurora A and Aurora B kinases with IC50 of 110 nM and 130 nM, respectively.	ZM447439

Research

Studies (12,149)

Timeframe	Studies, Drugs with This Role(%)	All Drugs %
pre-1990	566 (4.66)	18.7374
1990's	831 (6.84)	18.2507
2000's	2,682 (22.08)	29.6817
2010's	5,420 (44.61)	24.3611
2020's	2,650 (21.81)	2.80

Study Types

Publication Type	Studies, Drugs with this Role (%)	All Drugs (%)
Trials	240 (1.90%)	5.53%
Reviews	622 (4.93%)	6.00%
Case Studies	12 (0.10%)	4.05%
Observational	3 (0.02%)	0.25%
Other	11,743 (93.05%)	84.16%

Protein Targets (797)

Potency Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	Homo sapiens (human)	Potency	17.0841	1	3
15-lipoxygenase, partial	Homo sapiens (human)	Potency	0.7943	1	1
67.9K protein	Vaccinia virus	Potency	25.5154	1	2
activating transcription factor 6	Homo sapiens (human)	Potency	3.1164	1	1
aldehyde dehydrogenase 1 family, member A1	Homo sapiens (human)	Potency	31.3113	1	8
AR protein	Homo sapiens (human)	Potency	21.8585	5	7
aryl hydrocarbon receptor	Homo sapiens (human)	Potency	48.4412	2	4
arylsulfatase A	Homo sapiens (human)	Potency	33.8078	1	1
ATAD5 protein, partial	Homo sapiens (human)	Potency	20.5878	1	1
ATP-dependent phosphofructokinase	Trypanosoma brucei brucei TREU927	Potency	6.7456	1	1
Bloom syndrome protein isoform 1	Homo sapiens (human)	Potency	30.0082	2	4
Cellular tumor antigen p53	Homo sapiens (human)	Potency	56.1369	2	3
cellular tumor antigen p53 isoform a	Homo sapiens (human)	Potency	1.7560	2	2
Chain A, 2-oxoglutarate Oxygenase	Homo sapiens (human)	Potency	10.4876	1	4
Chain A, ATP-DEPENDENT DNA HELICASE Q1	Homo sapiens (human)	Potency	1.6182	2	7
Chain A, Cruzipain	Trypanosoma cruzi	Potency	20.9845	2	4
Chain A, HADH2 protein	Homo sapiens (human)	Potency	1.8958	2	5
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	Homo sapiens (human)	Potency	3.3893	2	8
Chain A, Putative fructose-1,6-bisphosphate aldolase	Giardia intestinalis	Potency	15.8114	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	Homo sapiens (human)	Potency	32.6570	1	3
Chain B, HADH2 protein	Homo sapiens (human)	Potency	1.8958	2	5
chromobox protein homolog 1	Homo sapiens (human)	Potency	44.6684	1	1
cytochrome P450 2C19 precursor	Homo sapiens (human)	Potency	15.8489	1	2
cytochrome P450 2C9 precursor	Homo sapiens (human)	Potency	11.9464	1	3
cytochrome P450 2D6 isoform 1	Homo sapiens (human)	Potency	35.7168	1	2
cytochrome P450 3A4 isoform 1	Homo sapiens (human)	Potency	6.3096	2	2
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	Homo sapiens (human)	Potency	25.8727	1	2
D(1A) dopamine receptor	Homo sapiens (human)	Potency	4.2880	2	2
Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)	Potency	31.6228	1	1
DNA polymerase beta	Homo sapiens (human)	Potency	0.1995	1	1
DNA polymerase eta isoform 1	Homo sapiens (human)	Potency	0.7943	1	1
DNA polymerase III, partial	Bacillus subtilis	Potency	10.6213	1	1
DNA polymerase iota isoform a (long)	Homo sapiens (human)	Potency	39.9975	1	2
DNA polymerase kappa isoform 1	Homo sapiens (human)	Potency	6.3354	1	8
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	18.9375	6	9
estrogen receptor 2 (ER beta)	Homo sapiens (human)	Potency	25.9324	1	2
estrogen-related nuclear receptor alpha	Homo sapiens (human)	Potency	29.7340	7	12
euchromatic histone-lysine N-methyltransferase 2	Homo sapiens (human)	Potency	20.3866	1	2
EWS/FLI fusion protein	Homo sapiens (human)	Potency	8.1690	4	20
flap endonuclease 1	Homo sapiens (human)	Potency	23.6712	2	4
Fumarate hydratase	Homo sapiens (human)	Potency	33.1734	1	2
GABA theta subunit	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
galactokinase	Homo sapiens (human)	Potency	42.1285	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit alpha-2	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit alpha-4	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit alpha-6	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit beta-1	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit beta-2	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit beta-3	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit delta	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit epsilon	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
Gamma-aminobutyric acid receptor subunit pi	Rattus norvegicus (Norway rat)	Potency	6.3096	1	1
GLI family zinc finger 3	Homo sapiens (human)	Potency	23.9189	2	4
GLS protein	Homo sapiens (human)	Potency	0.4467	1	1
glucocerebrosidase	Homo sapiens (human)	Potency	22.9287	1	4
glucocorticoid receptor [Homo sapiens]	Homo sapiens (human)	Potency	49.3919	1	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	Homo sapiens (human)	Potency	50.1187	1	1
Histamine H2 receptor	Cavia porcellus (domestic guinea pig)	Potency	12.6457	2	13
histone deacetylase 9 isoform 3	Homo sapiens (human)	Potency	24.5163	2	4
Histone H2A.x	Cricetulus griseus (Chinese hamster)	Potency	45.6500	2	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	Homo sapiens (human)	Potency	22.3872	1	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	Homo sapiens (human)	Potency	10.0000	2	2
Inositol monophosphatase 1	Rattus norvegicus (Norway rat)	Potency	11.2698	1	3
Integrin alpha-IIb	Homo sapiens (human)	Potency	2.5119	1	1
Integrin beta-3	Homo sapiens (human)	Potency	2.5119	1	1
Interferon beta	Homo sapiens (human)	Potency	13.1467	1	9
lamin isoform A-delta10	Homo sapiens (human)	Potency	14.1254	1	1
Luciferase	Photinus pyralis (common eastern firefly)	Potency	35.7340	1	2
M-phase phosphoprotein 8	Homo sapiens (human)	Potency	39.8107	1	1
Microtubule-associated protein tau	Homo sapiens (human)	Potency	7.6032	2	9
mitogen-activated protein kinase 1	Homo sapiens (human)	Potency	35.7168	2	2
muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	Potency	11.5574	2	2
muscleblind-like protein 1 isoform 1	Homo sapiens (human)	Potency	28.1838	1	1
neuropeptide S receptor isoform A	Homo sapiens (human)	Potency	0.1585	1	1
NFKB1 protein, partial	Homo sapiens (human)	Potency	5.6234	2	2
Nrf2	Homo sapiens (human)	Potency	20.5962	1	1
nuclear receptor ROR-gamma isoform 1	Mus musculus (house mouse)	Potency	21.1183	2	3
nuclear receptor subfamily 1, group I, member 3	Homo sapiens (human)	Potency	47.6768	2	4
Parkin	Homo sapiens (human)	Potency	6.6865	2	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens (human)	Potency	2.6855	1	1
peripheral myelin protein 22 isoform 1	Homo sapiens (human)	Potency	47.7548	1	1
peroxisome proliferator activated receptor gamma	Homo sapiens (human)	Potency	55.4186	1	1
peroxisome proliferator-activated receptor delta	Homo sapiens (human)	Potency	44.0206	1	1
phosphoglycerate kinase	Trypanosoma brucei brucei TREU927	Potency	7.5686	1	1
phosphopantetheinyl transferase	Bacillus subtilis	Potency	49.6967	1	5
polyprotein	Zika virus	Potency	33.1734	1	2
polyunsaturated fatty acid lipoxygenase ALOX12	Homo sapiens (human)	Potency	1.0610	1	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)	Potency	14.2191	1	2
PPM1D protein	Homo sapiens (human)	Potency	13.1467	1	6
pregnane X nuclear receptor	Homo sapiens (human)	Potency	65.1393	1	2
progesterone receptor	Homo sapiens (human)	Potency	14.5760	1	2
RAR-related orphan receptor gamma	Mus musculus (house mouse)	Potency	50.3870	2	4
regulator of G-protein signaling 4	Homo sapiens (human)	Potency	11.9173	1	1
retinoic acid nuclear receptor alpha variant 1	Homo sapiens (human)	Potency	28.0806	3	6
retinoid X nuclear receptor alpha	Homo sapiens (human)	Potency	15.9743	2	3
signal transducer and activator of transcription 6, interleukin-4 induced	Homo sapiens (human)	Potency	2.5119	2	2
SMAD family member 2	Homo sapiens (human)	Potency	15.4845	1	1
SMAD family member 3	Homo sapiens (human)	Potency	15.4845	1	1
Smad3	Homo sapiens (human)	Potency	35.4813	1	1
survival motor neuron protein isoform d	Homo sapiens (human)	Potency	35.4813	1	1
TDP1 protein	Homo sapiens (human)	Potency	14.1016	2	12
thioredoxin reductase	Rattus norvegicus (Norway rat)	Potency	23.7781	1	1
thyroid hormone receptor beta isoform 2	Rattus norvegicus (Norway rat)	Potency	60.8354	2	3
thyroid hormone receptor beta isoform a	Homo sapiens (human)	Potency	44.6684	1	1
thyroid stimulating hormone receptor	Homo sapiens (human)	Potency	35.2410	4	7
tyrosine-protein kinase Yes	Homo sapiens (human)	Potency	15.4103	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	Homo sapiens (human)	Potency	25.0578	2	2
USP1 protein, partial	Homo sapiens (human)	Potency	56.2341	1	1
v-jun sarcoma virus 17 oncogene homolog (avian)	Homo sapiens (human)	Potency	61.6448	1	1

Inhibition Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
1-deoxy-D-xylulose 5-phosphate reductoisomerase	Escherichia coli K-12	IC50	1.9000	1	1
17-beta-hydroxysteroid dehydrogenase type 2	Homo sapiens (human)	IC50	1.5400	2	2
3-oxoacyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	5.4000	1	1
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	IC50	4.0000	1	1
5'-nucleotidase	Rattus norvegicus (Norway rat)	Ki	0.0453	1	1
72 kDa type IV collagenase	Homo sapiens (human)	IC50	6.6800	1	1
Acetylcholinesterase	Homo sapiens (human)	Ki	38.3000	1	1
Adenosine receptor A1	Homo sapiens (human)	Ki	10.0000	1	1
Adenosine receptor A1	Rattus norvegicus (Norway rat)	Ki	8.9000	3	3
Adenosine receptor A2a	Homo sapiens (human)	Ki	10.0000	1	1
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	Ki	5.1250	2	2
Adenosine receptor A3	Homo sapiens (human)	Ki	15.3300	2	2
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	Homo sapiens (human)	IC50	37.9000	1	1
Aldo-keto reductase family 1 member A1	Rattus norvegicus (Norway rat)	IC50	2.3200	1	1
Aldo-keto reductase family 1 member A1	Sus scrofa (pig)	IC50	38.4000	1	1
Aldo-keto reductase family 1 member B1	Bos taurus (cattle)	IC50	17.7540	5	5
Aldo-keto reductase family 1 member B1	Homo sapiens (human)	IC50	2.2141	6	6
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	IC50	6.6417	5	6
Aldo-keto reductase family 1 member B1	Sus scrofa (pig)	IC50	50.1000	1	1
Aldo-keto reductase family 1 member C21	Mus musculus (house mouse)	IC50	6.9000	1	1
Aldo-keto reductase family 1 member C21	Mus musculus (house mouse)	Ki	11.0000	1	1
ALK tyrosine kinase receptor	Homo sapiens (human)	IC50	3.3200	1	1
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	IC50	39.9000	1	2
Alpha-amylase 1A	Homo sapiens (human)	IC50	21.4000	2	2
Alpha-synuclein	Homo sapiens (human)	IC50	20.0000	1	1
Amine oxidase [flavin-containing] A	Homo sapiens (human)	IC50	2.6200	2	2
Amine oxidase [flavin-containing] A	Bos taurus (cattle)	IC50	0.0100	1	1
Amine oxidase [flavin-containing] B	Bos taurus (cattle)	IC50	20.0000	1	1
Amine oxidase [flavin-containing] B	Homo sapiens (human)	IC50	64.3300	2	2
Amyloid-beta precursor protein	Homo sapiens (human)	IC50	40.7850	4	4
Anthrax toxin receptor 2	Homo sapiens (human)	IC50	300.0000	1	1
Arginase	Leishmania amazonensis	IC50	4.0000	1	1
Aromatase	Homo sapiens (human)	IC50	6.0060	2	2
ATP-binding cassette sub-family C member 3	Homo sapiens (human)	IC50	133.0000	1	1
ATP-dependent translocase ABCB1	Homo sapiens (human)	IC50	52.5000	1	1
Aurora kinase A	Homo sapiens (human)	IC50	0.3099	18	21
Aurora kinase A	Mus musculus (house mouse)	IC50	0.0390	1	1
Aurora kinase A	Homo sapiens (human)	Ki	1.0423	4	4
Aurora kinase B	Homo sapiens (human)	IC50	0.2560	23	27
Aurora kinase B	Homo sapiens (human)	Ki	0.0008	3	3
Aurora kinase B-A	Xenopus laevis (African clawed frog)	IC50	0.0450	1	1
Aurora kinase C	Homo sapiens (human)	IC50	0.1302	3	5
Aurora kinase C	Homo sapiens (human)	Ki	0.0170	1	1
B2 bradykinin receptor	Cavia porcellus (domestic guinea pig)	IC50	4.0000	2	2
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	1.5000	1	1
Beta-lactamase	Enterobacter cloacae	IC50	269.6667	3	3
Beta-lactamase	Escherichia coli K-12	IC50	58.0000	4	4
Beta-secretase 1	Homo sapiens (human)	IC50	7.6400	3	3
Beta-secretase 1	Homo sapiens (human)	Ki	14.0000	1	1
Bifunctional epoxide hydrolase 2	Homo sapiens (human)	IC50	20.2700	2	2
Bile salt export pump	Homo sapiens (human)	IC50	134.0000	2	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	IC50	7.2500	2	2
C-C chemokine receptor type 4	Homo sapiens (human)	IC50	47.2409	3	6
C-X-C chemokine receptor type 1	Homo sapiens (human)	IC50	35.3780	2	4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Rattus norvegicus (Norway rat)	IC50	275.0000	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	Rattus norvegicus (Norway rat)	IC50	275.0000	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	IC50	3.0000	1	1
Calmodulin-1	Homo sapiens (human)	IC50	12.9700	1	1
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Ki	10.0000	1	1
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Ki	10.0000	1	1
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Ki	10.0000	1	1
Canalicular multispecific organic anion transporter 1	Homo sapiens (human)	IC50	133.0000	1	1
Carbonic anhydrase 1	Homo sapiens (human)	Ki	29.9138	4	8
Carbonic anhydrase 12	Homo sapiens (human)	Ki	9.3900	1	1
Carbonic anhydrase 13	Mus musculus (house mouse)	Ki	9.0300	1	1
Carbonic anhydrase 14	Homo sapiens (human)	Ki	5.4100	1	1
Carbonic anhydrase 2	Homo sapiens (human)	Ki	29.8962	4	8
Carbonic anhydrase 3	Bos taurus (cattle)	Ki	6.5260	2	5
Carbonic anhydrase 3	Homo sapiens (human)	Ki	8.1000	1	1
Carbonic anhydrase 4	Homo sapiens (human)	Ki	6.7533	3	6
Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)	Ki	6.8100	1	1
Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)	Ki	11.9000	1	1
Carbonic anhydrase 6	Homo sapiens (human)	Ki	4.9500	2	2
Carbonic anhydrase 7	Homo sapiens (human)	Ki	4.8400	1	1
Carbonic anhydrase 9	Homo sapiens (human)	Ki	7.0000	1	1
Casein kinase II subunit alpha	Homo sapiens (human)	IC50	1.6500	5	5
Casein kinase II subunit alpha	Homo sapiens (human)	Ki	1.1800	4	4
Casein kinase II subunit alpha 3	Homo sapiens (human)	IC50	0.5500	1	1
Casein kinase II subunit alpha 3	Homo sapiens (human)	Ki	1.1800	1	1
Casein kinase II subunit alpha'	Homo sapiens (human)	IC50	1.6500	5	5
Casein kinase II subunit alpha'	Homo sapiens (human)	Ki	1.1800	1	1
Casein kinase II subunit beta	Homo sapiens (human)	IC50	1.6500	5	5
Casein kinase II subunit beta	Homo sapiens (human)	Ki	1.1800	1	1
Cationic trypsin	Bos taurus (cattle)	IC50	24.4200	2	5
cGMP-dependent 3',5'-cyclic phosphodiesterase	Rattus norvegicus (Norway rat)	IC50	81.3000	1	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	Helicobacter pylori	Ki	12.7000	1	3
Chain A, APH(2')-Id	Enterococcus casseliflavus	Ki	25.1000	1	1
Chain A, Serine/threonine-protein Kinase 12-a	Xenopus laevis (African clawed frog)	IC50	0.5000	1	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	Helicobacter pylori	Ki	12.7000	1	3
Chymotrypsin-C	Homo sapiens (human)	IC50	100.0000	1	1
Chymotrypsin-like elastase family member 1	Sus scrofa (pig)	IC50	28.7500	1	4
Chymotrypsinogen A	Bos taurus (cattle)	IC50	292.5000	2	2
Chymotrypsinogen B	Homo sapiens (human)	IC50	100.0000	1	1
Collagenase 3	Homo sapiens (human)	IC50	8.4600	1	1
Cyclin homolog	Herpesvirus saimiri (strain 11)	IC50	31.2750	1	4
Cyclin-dependent kinase 1	Homo sapiens (human)	IC50	25.0900	5	5
Cyclin-dependent kinase 1	Oryzias latipes (Japanese medaka)	IC50	31.2750	1	4
Cyclin-dependent kinase 2	Homo sapiens (human)	IC50	40.0000	1	1
Cyclin-dependent kinase 2	Homo sapiens (human)	Ki	10.0000	1	1
Cyclin-dependent kinase 4	Homo sapiens (human)	IC50	30.5195	2	2
Cyclin-dependent kinase 5 activator 1	Homo sapiens (human)	IC50	29.6200	2	5
Cyclin-dependent kinase 6	Homo sapiens (human)	IC50	30.0200	2	5
Cyclin-dependent-like kinase 5	Homo sapiens (human)	IC50	29.6200	2	5
Cytochrome P450 11B1, mitochondrial	Rattus norvegicus (Norway rat)	IC50	50.0000	1	1
Cytochrome P450 1A1	Homo sapiens (human)	IC50	8.4364	5	5
Cytochrome P450 1A1	Homo sapiens (human)	Ki	0.6600	1	1
Cytochrome P450 1A2	Homo sapiens (human)	IC50	14.6990	3	3
Cytochrome P450 1B1	Homo sapiens (human)	IC50	1.1108	5	5
Cytochrome P450 1B1	Homo sapiens (human)	Ki	0.0230	2	2
Cytochrome P450 2C8	Homo sapiens (human)	IC50	13.5000	2	2
Cytochrome P450 2C9	Homo sapiens (human)	Ki	27.0000	1	1
Cytochrome P450 2D6	Homo sapiens (human)	IC50	20.0000	2	2
Cytochrome P450 3A4	Homo sapiens (human)	IC50	15.6667	3	3
Cytosol aminopeptidase	Sus scrofa (pig)	IC50	34.3000	1	1
D(4) dopamine receptor	Homo sapiens (human)	Ki	7.8460	1	1
Death-associated protein kinase 1	Homo sapiens (human)	IC50	8.9000	1	1
Dipeptidyl peptidase 3	Homo sapiens (human)	IC50	74.1000	1	1
Dipeptidyl peptidase 4	Homo sapiens (human)	IC50	66.4600	2	2
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	IC50	10.0000	1	1
Dual specificity mitogen-activated protein kinase kinase 1	Mus musculus (house mouse)	IC50	0.0080	1	1
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Ki	10.0000	1	1
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Ki	10.0000	1	1
Dual specificity protein kinase TTK	Homo sapiens (human)	IC50	0.0034	2	2
ELAV-like protein 1	Homo sapiens (human)	IC50	1.4000	1	1
ELAV-like protein 3	Homo sapiens (human)	IC50	1.8000	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	Escherichia coli K-12	IC50	20.0000	1	1
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	1.8333	3	3
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	Ki	0.5283	3	3
Epidermal growth factor receptor	Homo sapiens (human)	IC50	51.4775	4	4
Epidermal growth factor receptor	Homo sapiens (human)	Ki	10.0000	1	1
Epoxide hydrolase 1	Homo sapiens (human)	IC50	7.0000	1	1
Fibroblast growth factor receptor 1	Homo sapiens (human)	Ki	10.0000	1	1
Fibroblast growth factor receptor 2	Homo sapiens (human)	Ki	10.0000	1	1
Fibroblast growth factor receptor 3	Homo sapiens (human)	Ki	10.0000	1	1
Fibroblast growth factor receptor 4	Homo sapiens (human)	Ki	10.0000	1	1
Focal adhesion kinase 1	Homo sapiens (human)	IC50	1.2000	1	1
Focal adhesion kinase 1	Homo sapiens (human)	Ki	10.0000	1	1
G-protein coupled receptor 35	Homo sapiens (human)	IC50	15.4000	1	1
G1/S-specific cyclin-D1	Homo sapiens (human)	IC50	30.5195	2	2
G2/mitotic-specific cyclin-B	Marthasterias glacialis (spiny starfish)	IC50	31.2750	1	4
G2/mitotic-specific cyclin-B1	Homo sapiens (human)	IC50	38.3333	3	3
G2/mitotic-specific cyclin-B2	Homo sapiens (human)	IC50	75.0000	1	1
G2/mitotic-specific cyclin-B3	Homo sapiens (human)	IC50	75.0000	1	1
glucose-6-phosphate dehydrogenase	Leuconostoc mesenteroides	IC50	25.0000	1	1
Glutathione reductase	Saccharomyces cerevisiae S288C	IC50	48.8000	1	1
Glutathione reductase, mitochondrial	Homo sapiens (human)	IC50	218.0000	1	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	Trypanosoma cruzi	IC50	142.0000	1	1
Glycogen phosphorylase, liver form	Homo sapiens (human)	IC50	4.8000	1	1
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	IC50	2.1000	1	1
Glycogen synthase kinase-3 beta	Homo sapiens (human)	IC50	2.1000	1	1
Glycogen synthase kinase-3 beta	Rattus norvegicus (Norway rat)	IC50	31.2750	1	4
Heat shock factor protein 1	Homo sapiens (human)	IC50	50.0000	1	1
Hepatocyte growth factor receptor	Homo sapiens (human)	IC50	0.5800	1	1
hexokinase	Trypanosoma brucei brucei TREU927	IC50	22.3780	1	1
Hypoxia-inducible factor 1-alpha inhibitor	Homo sapiens (human)	IC50	10.2000	1	1
Inositol hexakisphosphate kinase 2	Homo sapiens (human)	IC50	0.7000	1	1
Inositol polyphosphate multikinase	Homo sapiens (human)	IC50	2.3000	1	1
Insulin-like growth factor 1 receptor	Homo sapiens (human)	IC50	0.3000	1	1
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Ki	10.0000	1	1
Integrase	Human immunodeficiency virus 1	IC50	13.1600	5	5
Interstitial collagenase	Homo sapiens (human)	IC50	1.4900	1	1
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	IC50	1.0000	1	1
Lactoperoxidase	Bos taurus (cattle)	IC50	6.1000	1	1
Lactoylglutathione lyase	Homo sapiens (human)	IC50	3.2000	1	1
Lactoylglutathione lyase	Homo sapiens (human)	Ki	15.1356	1	1
Lysine-specific histone demethylase 1A	Homo sapiens (human)	IC50	1.2600	1	1
Lysosomal alpha-glucosidase	Homo sapiens (human)	IC50	7.8000	1	1
Macrophage metalloelastase	Homo sapiens (human)	IC50	10.2300	1	1
Malate dehydrogenase	Thermus thermophilus	IC50	6.0000	1	1
Maltase-glucoamylase, intestinal	Homo sapiens (human)	IC50	9.3000	2	2
Matrix metalloproteinase-9	Homo sapiens (human)	IC50	0.8919	2	2
Mitogen-activated protein kinase 10	Homo sapiens (human)	IC50	2.8800	1	2
Mitogen-activated protein kinase 14	Homo sapiens (human)	IC50	2.8800	1	2
Mitogen-activated protein kinase 14	Homo sapiens (human)	Ki	10.0000	1	1
Mitogen-activated protein kinase 8	Homo sapiens (human)	Ki	10.0000	1	1
Monocarboxylate transporter 1	Rattus norvegicus (Norway rat)	IC50	14.0000	1	1
Monocarboxylate transporter 2	Rattus norvegicus (Norway rat)	IC50	5.0000	1	1
Multidrug resistance-associated protein 1	Homo sapiens (human)	Ki	5.2500	2	2
Multidrug resistance-associated protein 4	Homo sapiens (human)	IC50	20.8000	1	1
Myeloperoxidase	Homo sapiens (human)	IC50	1.6975	4	4
NADPH oxidase 4	Homo sapiens (human)	IC50	0.6800	1	1
Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50	7.7500	1	1
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	IC50	53.9250	4	4
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	Ki	3.8000	1	1
Neutrophil elastase	Homo sapiens (human)	IC50	18.3390	2	2
Neutrophil elastase	Homo sapiens (human)	Ki	11.9000	1	1
Nitric oxide synthase, inducible	Mus musculus (house mouse)	IC50	16.4000	1	1
NUAK family SNF1-like kinase 1	Homo sapiens (human)	IC50	5.0900	1	1
Oligo-1,6-glucosidase IMA1	Saccharomyces cerevisiae S288C	IC50	530.0000	1	1
Pancreatic triacylglycerol lipase	Sus scrofa (pig)	IC50	70.0000	1	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	Homo sapiens (human)	IC50	3.8000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	IC50	8.7950	2	2
Phosphodiesterase	Rattus norvegicus (Norway rat)	IC50	275.0000	1	1
Phospholipase A2	Homo sapiens (human)	IC50	2.0000	1	1
Polyphenol oxidase 2	Agaricus bisporus	IC50	135.5000	2	2
Polyunsaturated fatty acid 5-lipoxygenase	Homo sapiens (human)	IC50	6.9580	5	5
Polyunsaturated fatty acid 5-lipoxygenase	Rattus norvegicus (Norway rat)	IC50	1.9500	6	6
Polyunsaturated fatty acid lipoxygenase ALOX12	Homo sapiens (human)	IC50	0.4400	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	Homo sapiens (human)	IC50	2.2000	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	IC50	18.7150	2	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)	IC50	100.0000	1	1
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	IC50	30.0000	1	1
Probable maltase-glucoamylase 2	Homo sapiens (human)	IC50	7.8000	1	1
Prolyl endopeptidase	Homo sapiens (human)	IC50	13.0000	1	1
Prostaglandin G/H synthase 1	Rattus norvegicus (Norway rat)	IC50	50.0000	2	2
Prostaglandin G/H synthase 2	Homo sapiens (human)	IC50	28.6000	1	1
Prostaglandin G/H synthase 2	Rattus norvegicus (Norway rat)	IC50	50.0000	2	2
Proteasome subunit beta type-5	Homo sapiens (human)	IC50	2.7500	2	2
Protein E6	Human papillomavirus 16	IC50	20.0000	1	1
Prothrombin	Homo sapiens (human)	IC50	15.7500	2	2
Prothrombin	Bos taurus (cattle)	IC50	28.7500	1	4
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	IC50	78.1000	1	1
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50	7.5600	2	2
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Ki	10.0000	1	1
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	IC50	5.3900	1	1
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	IC50	0.3450	2	2
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	IC50	23.8000	1	1
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	IC50	26.4250	4	4
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	Ki	7.4000	1	1
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	Ki	7.4000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Oryctolagus cuniculus (rabbit)	IC50	9.0000	1	1
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	Ki	106.7000	1	1
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	IC50	7.5890	1	1
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Ki	10.0000	1	1
Serine/threonine-protein kinase N1	Homo sapiens (human)	IC50	5.8000	1	1
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	IC50	5.7300	1	1
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	IC50	4.2300	1	1
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	Ki	10.0000	1	1
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	IC50	0.7686	5	5
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	IC50	21.1875	4	4
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Ki	10.0000	1	1
Short transient receptor potential channel 5	Homo sapiens (human)	IC50	6.5000	1	1
Sialidase	Clostridium perfringens	IC50	9.9200	5	5
Sialidase-2	Homo sapiens (human)	IC50	160.0000	1	1
Sodium- and chloride-dependent betaine transporter	Rattus norvegicus (Norway rat)	IC50	50.0000	1	1
Sodium- and chloride-dependent GABA transporter 1	Rattus norvegicus (Norway rat)	IC50	50.0000	1	1
Sodium- and chloride-dependent GABA transporter 2	Rattus norvegicus (Norway rat)	IC50	50.0000	1	1
Sodium- and chloride-dependent GABA transporter 3	Rattus norvegicus (Norway rat)	IC50	50.0000	1	1
Sodium-dependent dopamine transporter	Rattus norvegicus (Norway rat)	IC50	20.0000	1	1
Sodium-dependent serotonin transporter	Rattus norvegicus (Norway rat)	IC50	1.0000	1	1
Solute carrier family 2, facilitated glucose transporter member 2	Homo sapiens (human)	IC50	12.0000	2	2
Solute carrier family 2, facilitated glucose transporter member 4	Rattus norvegicus (Norway rat)	Ki	16.0000	1	1
Sorbitol dehydrogenase	Homo sapiens (human)	IC50	106.3000	2	2
Stromelysin-1	Homo sapiens (human)	IC50	5.5700	1	1
Substance-K receptor	Cavia porcellus (domestic guinea pig)	IC50	58.4000	1	1
Substance-P receptor	Cavia porcellus (domestic guinea pig)	IC50	58.4000	1	1
Sucrase-isomaltase, intestinal	Homo sapiens (human)	IC50	7.8000	1	1
Trypsin-1	Homo sapiens (human)	IC50	15.4000	1	1
Trypsin-2	Homo sapiens (human)	IC50	15.4000	1	1
Trypsin-3	Homo sapiens (human)	IC50	15.4000	1	1
Tyrosinase	Homo sapiens (human)	IC50	44.3800	1	1
Tyrosine-protein kinase CSK	Homo sapiens (human)	Ki	10.0000	1	1
Tyrosine-protein kinase JAK3	Homo sapiens (human)	Ki	10.0000	1	1
Tyrosine-protein kinase Lck	Homo sapiens (human)	IC50	13.0000	2	2
Tyrosine-protein kinase Lck	Homo sapiens (human)	Ki	0.1700	1	1
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	IC50	0.9600	1	1
Tyrosine-protein kinase SYK	Homo sapiens (human)	IC50	20.0000	1	1
Tyrosine-protein kinase transforming protein Abl	Abelson murine leukemia virus	Ki	10.0000	1	1
Tyrosine-protein kinase Yes	Homo sapiens (human)	Ki	0.4720	1	1
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	Ki	8.2000	1	1
Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)	IC50	23.3000	2	2
Urease subunit alpha	Helicobacter pylori 26695	IC50	11.1333	3	3
Urease subunit alpha	Helicobacter pylori 26695	Ki	9.3400	1	1
Urease subunit beta	Helicobacter pylori 26695	IC50	11.1333	3	3
Urease subunit beta	Helicobacter pylori 26695	Ki	9.3400	1	1
Urokinase-type plasminogen activator	Homo sapiens (human)	IC50	25.4200	2	5
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	IC50	0.9700	2	2
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Ki	1.8000	1	1
Vasopressin V2 receptor	Homo sapiens (human)	IC50	20.3282	3	6
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	IC50	31.9000	1	1
Xanthine dehydrogenase/oxidase	Homo sapiens (human)	IC50	3.0400	3	3
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	Ki	1.2000	1	1
Xanthine dehydrogenase/oxidase	Homo sapiens (human)	Ki	0.2800	1	1

Activation Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
26S proteasome regulatory subunit 6B	Homo sapiens (human)	Kd	30.0000	1	2
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
5-hydroxytryptamine receptor 1A	Homo sapiens (human)	EC50	100.0000	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	Kd	20.0000	3	4
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	Kd	10.0000	2	2
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	Kd	30.0000	1	2
5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)	Kd	30.0000	1	3
AarF domain-containing protein kinase 1	Homo sapiens (human)	Kd	30.0000	1	2
Actin-related protein 2	Homo sapiens (human)	Kd	30.0000	1	2
Actin-related protein 3	Homo sapiens (human)	Kd	30.0000	1	2
Activated CDC42 kinase 1	Homo sapiens (human)	Kd	22.0000	3	5
Activin receptor type-1	Homo sapiens (human)	Kd	20.0000	3	4
Activin receptor type-1B	Homo sapiens (human)	Kd	20.0000	3	4
Activin receptor type-2A	Homo sapiens (human)	Kd	10.0000	2	2
Activin receptor type-2B	Homo sapiens (human)	Kd	20.0000	3	4
Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)	Kd	30.0000	1	2
Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)	Kd	30.0000	1	2
Adenine phosphoribosyltransferase	Homo sapiens (human)	Kd	30.0000	1	2
Adenosine kinase	Homo sapiens (human)	Kd	30.0000	1	2
Adenylate kinase 2, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
ADP/ATP translocase 2	Homo sapiens (human)	Kd	30.0000	1	2
ADP/ATP translocase 3	Homo sapiens (human)	Kd	30.0000	1	2
ALK tyrosine kinase receptor	Homo sapiens (human)	Kd	10.0000	2	2
Angiopoietin-1 receptor	Homo sapiens (human)	Kd	1.9000	2	2
Angiotensin-converting enzyme 2	Homo sapiens (human)	EC50	83.4000	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)	Kd	1.5000	2	2
AP2-associated protein kinase 1	Homo sapiens (human)	Kd	18.2500	3	4
ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)	Kd	30.0000	1	2
ATP-dependent RNA helicase DDX1	Homo sapiens (human)	Kd	30.0000	1	2
ATP-dependent RNA helicase DDX3X	Homo sapiens (human)	Kd	30.0000	1	2
ATP-dependent RNA helicase DDX42	Homo sapiens (human)	Kd	30.0000	1	3
ATP-dependent RNA helicase DHX30	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent translocase ABCB1	Homo sapiens (human)	Kd	7.0795	1	1
Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)	Kd	20.0000	3	4
Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)	Kd	10.0000	2	2
Aurora kinase A	Homo sapiens (human)	Kd	0.2781	8	11
Aurora kinase B	Homo sapiens (human)	Kd	0.0046	3	3
Aurora kinase C	Homo sapiens (human)	Kd	0.0044	2	2
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	Kd	10.0000	2	2
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	Kd	30.0000	1	2
BMP-2-inducible protein kinase	Homo sapiens (human)	Kd	20.0000	3	4
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	Kd	20.0000	3	4
Bone morphogenetic protein receptor type-1B	Homo sapiens (human)	Kd	25.0000	2	4
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	Kd	20.0000	3	4
Breakpoint cluster region protein	Homo sapiens (human)	Kd	30.0000	1	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	EC50	0.1953	3	3
Calcium-dependent protein kinase 1	Plasmodium falciparum 3D7	Kd	10.0000	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	Kd	20.0000	3	4
Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	Kd	20.0000	3	4
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	Kd	20.0000	3	4
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	Kd	20.0000	3	4
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Kd	22.0000	3	5
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Kd	20.0000	3	4
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Kd	30.0000	1	2
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	Kd	10.0000	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)	Kd	30.0000	1	3
Casein kinase I isoform alpha	Homo sapiens (human)	Kd	23.3333	2	3
Casein kinase I isoform alpha-like	Homo sapiens (human)	Kd	10.0000	2	2
Casein kinase I isoform delta	Homo sapiens (human)	Kd	20.0000	3	4
Casein kinase I isoform epsilon	Homo sapiens (human)	Kd	20.0000	3	4
Casein kinase I isoform gamma-1	Homo sapiens (human)	Kd	20.0000	3	4
Casein kinase I isoform gamma-2	Homo sapiens (human)	Kd	20.0000	3	4
Casein kinase I isoform gamma-3	Homo sapiens (human)	Kd	20.0000	3	4
Casein kinase II subunit alpha	Homo sapiens (human)	Kd	10.0000	2	2
Casein kinase II subunit alpha'	Homo sapiens (human)	Kd	6.0410	3	4
Cell division control protein 2 homolog	Plasmodium falciparum 3D7	Kd	10.0000	1	1
cGMP-dependent protein kinase 1	Homo sapiens (human)	Kd	20.0000	3	4
cGMP-dependent protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)	Kd	30.0000	1	2
Citron Rho-interacting kinase	Homo sapiens (human)	Kd	17.8500	3	4
Cyclin-dependent kinase 1	Homo sapiens (human)	Kd	30.0000	1	2
Cyclin-dependent kinase 11A	Homo sapiens (human)	Kd	1.0000	2	2
Cyclin-dependent kinase 11B	Homo sapiens (human)	Kd	1.2000	2	2
Cyclin-dependent kinase 12	Homo sapiens (human)	Kd	30.0000	1	2
Cyclin-dependent kinase 13	Homo sapiens (human)	Kd	20.3667	2	3
Cyclin-dependent kinase 14	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 15	Homo sapiens (human)	Kd	10.0000	1	1
Cyclin-dependent kinase 16	Homo sapiens (human)	Kd	18.1500	3	4
Cyclin-dependent kinase 17	Homo sapiens (human)	Kd	20.0000	3	4
Cyclin-dependent kinase 18	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 19	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 2	Homo sapiens (human)	Kd	20.0000	3	4
Cyclin-dependent kinase 3	Homo sapiens (human)	Kd	20.0000	3	4
Cyclin-dependent kinase 4	Homo sapiens (human)	Kd	20.0000	3	4
Cyclin-dependent kinase 6	Homo sapiens (human)	Kd	30.0000	1	2
Cyclin-dependent kinase 7	Homo sapiens (human)	Kd	18.1000	3	4
Cyclin-dependent kinase 8	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 9	Homo sapiens (human)	Kd	20.0000	3	4
Cyclin-dependent kinase-like 1	Homo sapiens (human)	Kd	10.0000	1	1
Cyclin-dependent kinase-like 2	Homo sapiens (human)	Kd	1.2000	1	1
Cyclin-dependent kinase-like 3	Homo sapiens (human)	Kd	10.0000	1	1
Cyclin-dependent kinase-like 5	Homo sapiens (human)	Kd	20.0000	2	2
Cyclin-dependent-like kinase 5	Homo sapiens (human)	Kd	20.0000	3	4
Cyclin-G-associated kinase	Homo sapiens (human)	Kd	20.0000	3	4
Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	3
Cystic fibrosis transmembrane conductance regulator	Homo sapiens (human)	Kd	25.6000	1	1
Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
Cytochrome P450 1A1	Homo sapiens (human)	EC50	8.8000	1	1
Cytochrome P450 1B1	Homo sapiens (human)	EC50	1.1000	1	1
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	Kd	10.0000	2	2
dCTP pyrophosphatase 1	Homo sapiens (human)	Kd	30.0000	1	2
Death-associated protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
Death-associated protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
Death-associated protein kinase 3	Homo sapiens (human)	Kd	10.0000	3	3
Delta(24)-sterol reductase	Homo sapiens (human)	Kd	30.0000	1	3
Deoxycytidine kinase	Homo sapiens (human)	Kd	30.0000	1	2
Discoidin domain-containing receptor 2	Homo sapiens (human)	Kd	19.1500	3	4
DNA replication licensing factor MCM4	Homo sapiens (human)	Kd	30.0000	1	2
DNA topoisomerase 2-alpha	Homo sapiens (human)	Kd	30.0000	1	2
DNA topoisomerase 2-beta	Homo sapiens (human)	Kd	30.0000	1	2
DnaJ homolog subfamily A member 1	Homo sapiens (human)	Kd	30.0000	1	2
Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)	Kd	3.0000	1	1
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Kd	17.9750	3	4
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Kd	17.4750	3	4
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	Kd	20.0000	3	4
Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	Kd	0.1633	2	3
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	Kd	20.0000	3	4
Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)	Kd	10.0000	1	1
Dual specificity protein kinase CLK1	Homo sapiens (human)	Kd	20.0000	3	4
Dual specificity protein kinase CLK2	Homo sapiens (human)	Kd	20.0000	3	4
Dual specificity protein kinase CLK3	Homo sapiens (human)	Kd	20.0000	3	4
Dual specificity protein kinase CLK4	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity protein kinase TTK	Homo sapiens (human)	Kd	8.5000	2	2
Dual specificity testis-specific protein kinase 1	Homo sapiens (human)	Kd	20.0000	3	4
Dual specificity testis-specific protein kinase 2	Homo sapiens (human)	Kd	30.0000	1	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	Kd	17.9248	2	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	Kd	10.0000	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	Kd	10.0000	1	1
Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
eIF-2-alpha kinase GCN2	Homo sapiens (human)	Kd	10.0000	2	2
EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)	Kd	30.0000	1	2
Electron transfer flavoprotein subunit beta	Homo sapiens (human)	Kd	30.0000	1	2
Elongation factor Tu, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
Ephrin type-A receptor 1	Homo sapiens (human)	Kd	16.6667	3	3
Ephrin type-A receptor 2	Homo sapiens (human)	Kd	20.0000	3	4
Ephrin type-A receptor 3	Homo sapiens (human)	Kd	10.0000	2	2
Ephrin type-A receptor 4	Homo sapiens (human)	Kd	20.0000	3	4
Ephrin type-A receptor 5	Homo sapiens (human)	Kd	20.0000	3	4
Ephrin type-A receptor 6	Homo sapiens (human)	Kd	10.0000	2	2
Ephrin type-A receptor 7	Homo sapiens (human)	Kd	20.0000	3	4
Ephrin type-A receptor 8	Homo sapiens (human)	Kd	10.0000	2	2
Ephrin type-B receptor 1	Homo sapiens (human)	Kd	10.0000	2	2
Ephrin type-B receptor 2	Homo sapiens (human)	Kd	20.0000	3	4
Ephrin type-B receptor 3	Homo sapiens (human)	Kd	20.0000	3	4
Ephrin type-B receptor 4	Homo sapiens (human)	Kd	20.0000	3	4
Ephrin type-B receptor 6	Homo sapiens (human)	Kd	20.0167	2	3
Epidermal growth factor receptor	Homo sapiens (human)	Kd	3.3645	23	24
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	Kd	20.6000	3	6
Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)	Kd	11.9420	2	3
Eukaryotic translation initiation factor 5B	Homo sapiens (human)	Kd	30.0000	1	2
Exosome RNA helicase MTR4	Homo sapiens (human)	Kd	30.0000	1	2
Ferrochelatase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
Fibroblast growth factor receptor 1	Homo sapiens (human)	Kd	20.0000	3	4
Fibroblast growth factor receptor 2	Homo sapiens (human)	Kd	10.0000	2	2
Fibroblast growth factor receptor 3	Homo sapiens (human)	Kd	10.0000	4	4
Fibroblast growth factor receptor 4	Homo sapiens (human)	Kd	10.0000	2	2
Focal adhesion kinase 1	Homo sapiens (human)	Kd	20.0000	3	4
G protein-coupled receptor kinase 4	Homo sapiens (human)	Kd	10.0000	1	1
G-protein coupled receptor 35	Homo sapiens (human)	EC50	6.9750	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)	Kd	30.0000	1	2
Glycine--tRNA ligase	Homo sapiens (human)	Kd	30.0000	1	2
Glycogen phosphorylase, brain form	Homo sapiens (human)	Kd	30.0000	1	2
Glycogen phosphorylase, liver form	Homo sapiens (human)	Kd	30.0000	1	2
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Kd	20.0000	3	4
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Kd	20.0000	3	4
GTP-binding nuclear protein Ran	Homo sapiens (human)	Kd	30.0000	1	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)	Kd	30.0000	1	2
Heme oxygenase 2	Homo sapiens (human)	Kd	30.0000	1	2
Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	15.9500	5	6
Heterogeneous nuclear ribonucleoprotein A1	Homo sapiens (human)	Kd	5.3000	1	2
High affinity nerve growth factor receptor	Homo sapiens (human)	Kd	16.6667	3	3
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	Kd	10.0000	1	1
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	Kd	3.7000	1	1
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	Kd	2.5000	1	1
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	Kd	0.0970	1	1
Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)	Kd	10.0000	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)	Kd	10.0000	1	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	Kd	10.0000	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	Kd	22.0000	3	5
Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)	Kd	30.0000	1	2
Insulin receptor	Homo sapiens (human)	Kd	20.0000	3	4
Insulin receptor-related protein	Homo sapiens (human)	Kd	10.0000	2	2
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Kd	20.0000	3	4
Integrin-linked protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)	Kd	10.0000	2	2
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	Kd	23.3333	2	3
Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)	Kd	19.4750	3	4
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	Kd	23.3333	2	3
Interstitial collagenase	Homo sapiens (human)	Kd	51.8000	1	1
Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
Leukocyte tyrosine kinase receptor	Homo sapiens (human)	Kd	3.2000	2	2
Leukotriene C4 synthase	Cavia porcellus (domestic guinea pig)	Kd	10.0000	1	1
LIM domain kinase 1	Homo sapiens (human)	Kd	20.0000	3	4
LIM domain kinase 2	Homo sapiens (human)	Kd	22.0000	3	5
Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)	Kd	30.0000	1	2
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	Kd	1.4000	2	2
Macrophage-stimulating protein receptor	Homo sapiens (human)	Kd	4.6413	2	3
MAP kinase-activated protein kinase 2	Homo sapiens (human)	Kd	20.0000	3	4
MAP kinase-activated protein kinase 3	Homo sapiens (human)	Kd	30.0000	1	2
MAP kinase-activated protein kinase 5	Homo sapiens (human)	Kd	20.0000	3	4
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	5.6000	2	2
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	Kd	20.0000	3	4
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	Kd	16.6667	3	3
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Kd	1.1505	16	16
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	Kd	20.0000	3	4
Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)	Kd	10.0000	1	1
Membrane-associated progesterone receptor component 1	Homo sapiens (human)	Kd	30.0000	1	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)	Kd	20.0000	3	4
Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	1	1
Midasin	Homo sapiens (human)	Kd	30.0000	1	2
Misshapen-like kinase 1	Homo sapiens (human)	Kd	20.0000	2	2
Mitogen-activated protein kinase 1	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase 10	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase 11	Homo sapiens (human)	Kd	22.0000	3	5
Mitogen-activated protein kinase 12	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase 13	Homo sapiens (human)	Kd	10.0000	1	1
Mitogen-activated protein kinase 14	Homo sapiens (human)	Kd	22.0000	3	5
Mitogen-activated protein kinase 15	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase 3	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase 4	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase 6	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase 7	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase 8	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase 9	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	Kd	25.0000	2	4
Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)	Kd	10.0000	1	1
Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)	Kd	10.0000	1	1
Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)	Kd	10.0000	1	1
Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)	Kd	2.4000	1	1
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	Kd	23.3333	2	3
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	Kd	15.8500	3	4
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	Kd	23.3333	2	3
Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	Kd	25.0000	2	4
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	Kd	0.6500	1	1
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)	Kd	23.3333	2	3
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	Kd	20.0000	3	4
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	Kd	0.8640	3	4
Multifunctional protein ADE2	Homo sapiens (human)	Kd	30.0000	1	2
Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)	Kd	1.5000	2	2
Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)	Kd	10.0000	2	2
Myosin light chain kinase 3	Homo sapiens (human)	Kd	23.3333	2	3
Myosin light chain kinase family member 4	Homo sapiens (human)	Kd	10.0000	2	2
Myosin light chain kinase, smooth muscle	Gallus gallus (chicken)	Kd	10.0000	1	1
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Kd	20.0000	3	4
Myosin-10	Homo sapiens (human)	Kd	30.0000	1	1
Myosin-14	Homo sapiens (human)	Kd	30.0000	1	3
Myosin-IIIa	Homo sapiens (human)	Kd	10.0000	2	2
Myosin-IIIb	Homo sapiens (human)	Kd	10.0000	2	2
Myotonin-protein kinase	Homo sapiens (human)	Kd	10.0000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	Kd	30.0000	1	2
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	Kd	20.0000	3	4
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	Kd	18.0000	4	5
NT-3 growth factor receptor	Homo sapiens (human)	Kd	10.0000	2	2
NUAK family SNF1-like kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
NUAK family SNF1-like kinase 2	Homo sapiens (human)	Kd	22.0000	3	5
Nucleolar GTP-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	2
Obg-like ATPase 1	Homo sapiens (human)	Kd	30.0000	1	2
Peripheral plasma membrane protein CASK	Homo sapiens (human)	Kd	10.0000	1	1
Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)	Kd	30.0000	1	2
Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)	Kd	30.0000	1	2
Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)	Kd	30.0000	1	2
Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	2
Phosphatidylinositol 4-kinase beta	Homo sapiens (human)	Kd	10.0000	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)	Kd	10.0000	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)	Kd	10.0000	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)	Kd	10.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	Kd	10.0000	12	12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	Kd	10.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	Kd	10.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	Kd	10.0000	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)	Kd	30.0000	1	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)	Kd	23.3333	2	3
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	Kd	20.0000	3	4
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)	Kd	10.0000	2	2
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	Kd	0.0380	3	3
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Kd	6.5630	4	5
Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)	Kd	30.0000	1	2
Procathepsin L	Homo sapiens (human)	EC50	83.4000	1	1
Prostaglandin G/H synthase 2	Homo sapiens (human)	Kd	10.0000	1	1
Protein kinase C alpha type	Homo sapiens (human)	Kd	30.0000	1	2
Protein kinase C beta type	Homo sapiens (human)	Kd	30.0000	1	2
Protein kinase C delta type	Homo sapiens (human)	Kd	20.0000	3	4
Protein kinase C epsilon type	Homo sapiens (human)	Kd	10.0000	2	2
Protein kinase C eta type	Homo sapiens (human)	Kd	10.0000	2	2
Protein kinase C iota type	Homo sapiens (human)	Kd	23.3333	2	3
Protein kinase C theta type	Homo sapiens (human)	Kd	16.6667	3	3
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	Kd	20.0000	3	4
Protein-tyrosine kinase 6	Homo sapiens (human)	Kd	12.6365	3	4
Prothrombin	Homo sapiens (human)	Kd	0.0387	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Kd	0.2608	8	9
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	Kd	10.0000	2	2
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Kd	20.0000	3	4
Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)	Kd	30.0000	1	2
Pyridoxal kinase	Homo sapiens (human)	Kd	30.0000	1	2
Rab-like protein 3	Homo sapiens (human)	Kd	30.0000	1	2
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	3	4
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	3	4
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	3	4
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	Kd	10.0000	2	2
Ras-related protein Rab-10	Homo sapiens (human)	Kd	30.0000	1	2
Ras-related protein Rab-27A	Homo sapiens (human)	Kd	30.0000	1	1
Ras-related protein Rab-6A	Homo sapiens (human)	Kd	15.0165	1	2
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	Kd	4.3000	2	2
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	Kd	10.0000	1	1
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	Kd	0.4700	1	1
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	13.0900	3	5
Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	30.0000	1	2
Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	10.0000	1	1
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	Kd	0.1779	14	15
Replicase polyprotein 1a	Severe acute respiratory syndrome-related coronavirus	EC50	83.4000	2	2
Replicase polyprotein 1ab	Betacoronavirus England 1	EC50	83.4000	1	1
Replicase polyprotein 1ab	Human coronavirus 229E	EC50	83.4000	2	2
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	EC50	83.4000	1	1
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	EC50	83.4000	2	2
Rho-associated protein kinase 1	Homo sapiens (human)	Kd	23.3333	2	3
Rho-associated protein kinase 2	Homo sapiens (human)	Kd	23.3333	2	3
Rhodopsin kinase GRK1	Homo sapiens (human)	Kd	10.0000	1	1
Rhodopsin kinase GRK7	Homo sapiens (human)	Kd	10.0000	1	1
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	Kd	16.6667	5	6
Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)	Kd	10.0000	4	4
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	Kd	20.0000	3	4
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	Kd	16.6667	5	6
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	Kd	16.6667	5	6
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	Kd	16.6667	5	6
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	Kd	20.9333	2	3
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	Kd	30.0000	1	2
RNA cytidine acetyltransferase	Homo sapiens (human)	Kd	30.0000	1	2
S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)	Kd	30.0000	1	2
Septin-9	Homo sapiens (human)	Kd	30.0000	1	2
Serine/threonine-protein kinase 10	Homo sapiens (human)	Kd	16.4000	3	4
Serine/threonine-protein kinase 16	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase 17A	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 17B	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 24	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase 25	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 26	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase 32A	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase 32B	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 32C	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 33	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 35	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase 36	Homo sapiens (human)	Kd	4.6000	2	2
Serine/threonine-protein kinase 38	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase 38-like	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	Kd	30.0000	1	1
Serine/threonine-protein kinase ATR	Homo sapiens (human)	Kd	30.0000	1	1
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Kd	16.6667	5	6
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase BRSK2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	Kd	1.4000	1	1
Serine/threonine-protein kinase D1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase D2	Homo sapiens (human)	Kd	22.0000	3	5
Serine/threonine-protein kinase D3	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase DCLK1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase DCLK2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase DCLK3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase ICK	Homo sapiens (human)	Kd	23.3333	2	3
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase LATS2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase MAK	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	Kd	22.0000	3	5
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	Kd	22.0000	3	5
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase N1	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase N2	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase Nek11	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	Kd	23.3333	2	3
Serine/threonine-protein kinase Nek4	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase Nek5	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase Nek7	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase NIM1	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase NLK	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase OSR1	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	Kd	16.0050	4	5
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase pim-3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PknB	Mycobacterium tuberculosis H37Rv	Kd	10.0000	1	1
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Kd	17.3500	3	4
Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase receptor R3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase RIO1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase RIO2	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase RIO3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase SBK1	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase Sgk3	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase SIK1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	Kd	23.3333	2	3
Serine/threonine-protein kinase STK11	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	Kd	23.3333	2	3
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	Kd	23.3333	2	3
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	Kd	23.3333	2	3
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	Kd	23.3333	2	3
Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	Kd	23.3333	2	3
Serine/threonine-protein kinase ULK2	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	Kd	25.0000	2	4
Serine/threonine-protein kinase VRK2	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	Kd	23.3333	2	3
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	Kd	30.0000	1	2
Signal recognition particle receptor subunit alpha	Homo sapiens (human)	Kd	30.0000	1	1
SNF-related serine/threonine-protein kinase	Homo sapiens (human)	Kd	10.0000	1	1
Spike glycoprotein	Betacoronavirus England 1	EC50	83.4000	1	1
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	EC50	83.4000	1	1
SRSF protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
SRSF protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
SRSF protein kinase 3	Homo sapiens (human)	Kd	10.0000	1	1
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	3	4
STE20-related kinase adapter protein alpha	Homo sapiens (human)	Kd	30.0000	1	2
STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)	Kd	10.0000	1	1
Structural maintenance of chromosomes protein 1A	Homo sapiens (human)	Kd	30.0000	1	2
Structural maintenance of chromosomes protein 2	Homo sapiens (human)	Kd	30.0000	1	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
TGF-beta receptor type-1	Homo sapiens (human)	Kd	20.0000	3	4
TGF-beta receptor type-2	Homo sapiens (human)	Kd	20.0000	3	4
Thyroid hormone receptor-associated protein 3	Homo sapiens (human)	Kd	30.0000	1	2
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	Kd	19.6250	3	4
Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)	Kd	10.0000	1	1
Transmembrane protease serine 2	Homo sapiens (human)	EC50	83.4000	1	1
Tubulin alpha-1A chain	Rattus norvegicus (Norway rat)	Kd	0.4700	1	1
Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	2
Tyrosine-protein kinase ABL1	Homo sapiens (human)	Kd	7.5942	23	24
Tyrosine-protein kinase ABL2	Homo sapiens (human)	Kd	22.0000	3	5
Tyrosine-protein kinase Blk	Homo sapiens (human)	Kd	1.5000	2	2
Tyrosine-protein kinase BTK	Homo sapiens (human)	Kd	17.8000	3	4
Tyrosine-protein kinase CSK	Homo sapiens (human)	Kd	18.4500	3	4
Tyrosine-protein kinase Fer	Homo sapiens (human)	Kd	20.0000	3	4
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	Kd	20.0000	3	4
Tyrosine-protein kinase Fgr	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase FRK	Homo sapiens (human)	Kd	20.0000	3	4
Tyrosine-protein kinase Fyn	Homo sapiens (human)	Kd	20.0000	3	4
Tyrosine-protein kinase HCK	Homo sapiens (human)	Kd	10.1715	3	4
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase JAK1	Homo sapiens (human)	Kd	18.0000	4	5
Tyrosine-protein kinase JAK2	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase JAK3	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase Lck	Homo sapiens (human)	Kd	8.3630	3	4
Tyrosine-protein kinase Lyn	Homo sapiens (human)	Kd	9.2083	3	4
Tyrosine-protein kinase Mer	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)	Kd	0.3500	2	2
Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	Kd	0.3900	2	2
Tyrosine-protein kinase Srms	Homo sapiens (human)	Kd	7.9000	2	2
Tyrosine-protein kinase SYK	Homo sapiens (human)	EC50	35.0000	1	1
Tyrosine-protein kinase SYK	Homo sapiens (human)	Kd	20.0000	3	4
Tyrosine-protein kinase Tec	Homo sapiens (human)	Kd	20.0000	3	4
Tyrosine-protein kinase TXK	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase Yes	Homo sapiens (human)	Kd	16.9000	3	4
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	Kd	10.0000	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)	Kd	30.0000	1	2
UMP-CMP kinase	Homo sapiens (human)	Kd	30.0000	1	1
Uncharacterized aarF domain-containing protein kinase 5	Homo sapiens (human)	Kd	30.0000	1	1
Uncharacterized protein FLJ45252	Homo sapiens (human)	Kd	30.0000	1	2
Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)	Kd	10.0000	1	1
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Kd	0.1100	2	2
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Kd	0.5000	2	2
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Kd	6.4500	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
Wee1-like protein kinase	Homo sapiens (human)	Kd	22.0000	3	5
Wee1-like protein kinase 2	Homo sapiens (human)	Kd	10.0000	1	1

Other Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
Adenosine receptor A3	Homo sapiens (human)	Kb	0.4660	1	1
interferon gamma precursor	Homo sapiens (human)	AC50	16.6900	2	2
Polyphenol oxidase 2	Agaricus bisporus	ID50	70.0000	1	1
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	Km	114.8000	2	2
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	Vmax	0.0070	2	2
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	Km	65.3000	4	4