A furanocoumarin with a 7H-furo[3,2-g]chromen-7-one skeleton and its substituted derivatives thereof.
| Member | Definition | Role |
|---|
| 3-(3,5-dimethyl-7-oxo-6-furo[3,2-g][1]benzopyranyl)propanoic acid | | 3-(3,5-dimethyl-7-oxo-6-furo[3,2-g][1]benzopyranyl)propanoic acid |
| 3-carbethoxypsoralen | | 3-(ethoxycarbonyl)psoralen |
| 3-methyl-5-propyl-7-furo[3,2-g][1]benzopyranone | | 3-methyl-5-propyl-7-furo[3,2-g][1]benzopyranone |
| 4-(2,3-Dihydroxy-3-methylbutoxy)furo(3,2-g)chromen-7-one | | 4-(2,3-Dihydroxy-3-methylbutoxy)furo(3,2-g)chromen-7-one |
| 5-(4-phenylbutoxy)psoralen | A member of the class of psoralens that is psoralen substituted by a 4-phenylbutoxy group at position 5. It is a potent inhibitor of the voltage-gated potassium channel Kv1.3 (EC50 = 3 nM). | psora 4 |
| 5-methoxypsoralen | A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5. | 5-methoxypsoralen |
| 6',7'-dihydroxybergamottin | | 6',7'-Dihydroxybergamottin |
| 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-7h-furo(3,2-g)(1)benzopyran-7-one | | Byakangelicin |
| acetic acid 2-(7-oxo-2,3-dihydrofuro[3,2-g][1]benzopyran-2-yl)propan-2-yl ester | | acetic acid 2-(7-oxo-2,3-dihydrofuro[3,2-g][1]benzopyran-2-yl)propan-2-yl ester |
| bergaptol | | bergaptol |
| byakangelicol | | Byakangelicol |
| cnidilin | | Cnidilin |
| epoxybergamottin | | Epoxybergamottin |
| ficusin | The simplest member of the class of psoralens that is 7H-furo[3,2-g]chromene having a keto group at position 7. It has been found in plants like Psoralea corylifolia and Ficus salicifolia. | psoralen |
| imperatorin | A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor. | imperatorin |
| isoimperatorin | A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 5. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor. | isoimperatorin |
| isopimpinellin | | isopimpinellin |
| methoxsalen | A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis. | methoxsalen |
| Neobyakangelicol | | Neobyakangelicol |
| oxypeucadanin | | (R)-Oxypeucedanin |
| phellopterin | | Phellopterin |
| rutamarin | | Chalepin acetate |
| trioxsalen | 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis. | trioxsalen |