Page last updated: 2024-09-27

Typhus, Epidemic Louse-Borne

The classic form of typhus, caused by RICKETTSIA PROWAZEKII, which is transmitted from man to man by the louse Pediculus humanus corporis. This disease is characterized by the sudden onset of intense headache, malaise, and generalized myalgia followed by the formation of a macular skin eruption and vascular and neurologic disturbances.

Synonyms(1)

Synonym
Typhus, Epidemic Louse-Borne

Research

Studies (267)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990231 (86.52)23.3326
1990's7 (2.62)12.5806
2000's15 (5.62)18.1394
2010's14 (5.24)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
benzoic acid0low20
fosmidomycin0low10
formaldehyde0low20
glycine0low10
histamine0low10
niacin0low10
orotic acid0low10
4-aminobenzoic acid0low120
pyridoxine0low10
pyruvic acid0low10
sulfites0low10
thiamine0low10
uracil0low10
urea0low10
mercaptoethanol0low20
amantadine0low10
caffeine0low10
ddt0low230
glutaral0low10
heptachlor0low10
indomethacin0low10
malathion0low10
methoxychlor0low10
ethylmaleimide0low10
oxyphenbutazone0low10
phenylbutazone0low20
4-aminobenzoic acid0low20
probenecid0low10
sulfamethoxazole0medium31
sulfanilamide0low20
sulfathiazole0low10
thalidomide0low10
nikethamide0low10
trimethoprim0medium31
corticosterone0low10
prednisolone0low10
prednisone0low30
estrone0low10
idoxuridine0low10
chloramphenicol0medium601
lysine0low10
cyanides0low10
chlordan0low10
methionine0low10
cycloheximide0low20
ampicillin0low10
cytarabine0low10
ethanethiol0low10
n-vinyl-2-pyrrolidinone0low10
4-bromophenacyl bromide0low10
oxophenarsine0low10
18-hydroxycorticosterone0low10
erythromycin0low30
nitrosoguanidines0low10
fluorescein0low10
streptomycin0low40
thiamphenicol0low10
cetylpyridinium chloride anhydrous0low10
tetrachloroethylene0low10
4-methoxyamphetamine0low20
8-bromo cyclic adenosine monophosphate0low10
tridemorph0low10
glutamic acid0low20
amoxicillin0low10
glucose, (beta-d)-isomer0low10
metaperiodate0low10
8-chloro-cyclic adenosine monophosphate0low10
hydrogen sulfite0low10
1-hexadecyl-2-acetyl-glycero-3-phosphocholine0low10
snp nonapeptide0low10
cortisone0low140
trimethoprim, sulfamethoxazole drug combination0medium11
salicin0low10
inositol 3-phosphate0low10
retinol0low10
fosfomycin0low10
zithromax0medium21
riboflavin0low10
isomethyleugenol0low10
retinaldehyde0low10
dieldrin0low30
quinine0low10
17-ketosteroids0low10
vitamin k semiquinone radical0low10
phenylephrine hydrochloride0low10
aluminum0low10
arsenic0low10
cysteine0low10
phosphorus0low10
proguanil0low10
pituitrin0low20
enerbol0low30
clove0low20
acid phosphatase0low10
nad0low10
sodium ethylxanthate0low10
cardiovascular agents0low10
endrin0low10
ascorbic acid0low10
tetracycline0low160
chlortetracycline0low210
oxytetracycline, anhydrous0low80
hyaluronoglucosaminidase0low10
aldrin0low10
muramidase0low10
exudates0low60
folic acid0low10
rifampin0low20
eye0low50

Protein Targets (965)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE190019
Chain A, Cruzipain7007
regulator of G-protein signaling 48008
Platelet-activating factor receptor0202
Inositol monophosphatase 15005
Genome polyprotein 0011
USP1 protein, partial140014
AR protein450045
thyroid stimulating hormone receptor150015
glucocorticoid receptor [Homo sapiens]310031
retinoic acid nuclear receptor alpha variant 1360036
estrogen nuclear receptor alpha540054
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a190019
Histone H2A.x150015
chromobox protein homolog 1240024
transcriptional regulator ERG isoform 33003
geminin250025
Polyphenol oxidase 20404
Cellular tumor antigen p53290029
Thiopurine S-methyltransferase0101
Succinate-semialdehyde dehydrogenase, mitochondrial0101
4-aminobutyrate aminotransferase, mitochondrial0101
Cytochrome P450 1B10303
Dihydropteroate synthase 0011
Chain A, Toluene-4-monooxygenase system protein A0101
[tau protein] kinase 0101
Phospholipase A20101
cAMP-dependent protein kinase catalytic subunit alpha0101
cAMP-dependent protein kinase catalytic subunit gamma0101
cAMP-dependent protein kinase catalytic subunit beta0101
Glycogen synthase kinase-3 beta0101
5-hydroxytryptamine receptor 2C0214
5-hydroxytryptamine receptor 2A0516
5-hydroxytryptamine receptor 1A0112
5-hydroxytryptamine receptor 1B0112
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0314
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0213
Sodium-dependent serotonin transporter0202
5-hydroxytryptamine receptor 7 0011
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
estrogen-related nuclear receptor alpha440044
Carbonic anhydrase 1010013
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0505
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0303
TDP1 protein280028
thyroid hormone receptor beta isoform 2350035
lamin isoform A-delta10170017
acetylcholinesterase120012
thioredoxin reductase130013
RAR-related orphan receptor gamma330033
NFKB1 protein, partial4004
GLI family zinc finger 3370037
signal transducer and activator of transcription 6, interleukin-4 induced1001
EWS/FLI fusion protein100010
putative alpha-glucosidase1001
euchromatic histone-lysine N-methyltransferase 2230023
heat shock protein beta-1220022
peripheral myelin protein 227007
histone acetyltransferase KAT2A isoform 15005
Solute carrier family 22 member 20306
Solute carrier family 22 member 1 07010
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Matrix protein 20112
Matrix protein 20123
Glutamate receptor ionotropic, NMDA 1 0528
Spike glycoprotein8019
Glutamate receptor ionotropic, NMDA 2A 0528
Glutamate receptor ionotropic, NMDA 2B0528
Glutamate receptor ionotropic, NMDA 2C0528
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, NMDA 2D0528
Solute carrier family 22 member 108010
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B0528
Multidrug and toxin extrusion protein 10505
Solute carrier family 22 member 20809
Glutamate receptor ionotropic, NMDA 3A0528
ATP-dependent phosphofructokinase9009
hypoxia-inducible factor 1 alpha subunit170017
SMAD family member 2120012
SMAD family member 3120012
nuclear receptor subfamily 1, group I, member 3250025
retinoid X nuclear receptor alpha330033
farnesoid X nuclear receptor220022
pregnane X nuclear receptor290029
peroxisome proliferator-activated receptor delta180018
peroxisome proliferator activated receptor gamma290029
vitamin D (1,25- dihydroxyvitamin D3) receptor270027
activating transcription factor 6210021
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a170017
nuclear factor erythroid 2-related factor 2 isoform 1340034
Dihydrofolate reductase0404
Dihydrofolate reductase0304
Dihydrofolate reductase0304
Dihydrofolate reductase0314
Folylpolyglutamate synthase, mitochondrial0103
Solute carrier organic anion transporter family member 1A30303
Folylpolyglutamate synthase, mitochondrial0003
Chain A, Beta-lactamase7007
Chain A, 2-oxoglutarate Oxygenase8008
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
apical membrane antigen 1, AMA14004
Beta-lactamase 0002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)170017
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
DNA polymerase kappa isoform 18008
ATP-binding cassette sub-family C member 3016016
Multidrug resistance-associated protein 4016017
Bile salt export pump0606
Bile salt export pump027027
Beta-lactamase SHV-10002
Beta-lactamase SHV-10002
Cytochrome P450 2C9 0617
Beta-lactamase0002
Kappa-type opioid receptor0204
Solute carrier family 15 member 10404
Solute carrier family 15 member 10202
Cytochrome P450 2J20404
B2 metallo-beta-lactamase 0002
Solute carrier family 15 member 20303
Beta-lactamase 0002
Beta-lactamase 0002
Solute carrier family 15 member 20303
Beta-lactamase 0002
Beta-lactamase 0002
Canalicular multispecific organic anion transporter 1016016
Chain A, Mutant Al2 6e7p9g0011
Chain A, ATP-DEPENDENT DNA HELICASE Q14004
Beta-lactamase 0002
acid sphingomyelinase3003
GLS protein7007
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-beta-lactamase type 20002
Metallo-beta-lactamase VIM-11 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0002
Metallo-beta-lactamase0002
Beta-lactamase 0002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 18008
DNA polymerase beta4004
Carbonic anhydrase 209114
60 kDa heat shock protein, mitochondrial0404
Beta-lactamase OXA-70001
10 kDa heat shock protein, mitochondrial0404
Angiopoietin-1 receptor0011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Thiosulfate sulfurtransferase0404
Metallo-beta-lactamase VIM-130002
Efflux transporter 0002
Beta-lactamase 0001
Beta-lactamase Toho-10002
Beta-lactamase 0002
Class D beta-lactamase0002
60 kDa chaperonin 0404
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0114
10 kDa chaperonin 0404
Metallo-b-lactamase 0002
Carbapenem-hydrolyzing beta-lactamase KPC0002
Histamine H3 receptor0102
Beta-lactamase class B VIM-2 0002
Beta-lactamase VIM-1 0002
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase5005
cytochrome P450 family 3 subfamily A polypeptide 4170017
IDH16006
nuclear factor erythroid 2-related factor 2 isoform 28008
lethal(3)malignant brain tumor-like protein 1 isoform I2002
lethal factor (plasmid)130013
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0202
Alpha-2B adrenergic receptor0011
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Oxygen-insensitive Nad(p)h Nitroreductase0101
Chain B, Oxygen-insensitive Nad(p)h Nitroreductase0101
Luciferase100010
estrogen receptor 2 (ER beta)220022
D-amino-acid oxidase0011
Neuronal acetylcholine receptor subunit alpha-43205
Neuronal acetylcholine receptor subunit beta-23205
D-amino-acid oxidase0314
Metabotropic glutamate receptor 50124
Alpha-glucosidase MAL120101
Monocarboxylate transporter 10002
Nicotinate phosphoribosyltransferase0404
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
D-aspartate oxidase0202
Serine racemase0202
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
phosphopantetheinyl transferase9009
thyroid stimulating hormone receptor140014
v-jun sarcoma virus 17 oncogene homolog (avian)230023
atrial natriuretic peptide receptor 1 precursor2002
thyroid hormone receptor beta isoform a110011
nuclear receptor ROR-gamma isoform 18008
muscarinic acetylcholine receptor M13003
Voltage-dependent calcium channel gamma-2 subunit140014
Potassium channel subfamily K member 20112
Glycogen phosphorylase, muscle form0202
Renin0101
Cholinesterase0202
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0112
Adenosine receptor A30101
Replicase polyprotein 1ab0112
Glutamate receptor 2142117
Amine oxidase [flavin-containing] A0101
Acetylcholinesterase0202
Adenosine receptor A10305
Amine oxidase [flavin-containing] B0202
Adenosine receptor A30101
Adenosine receptor A2a0214
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10114
Adenosine receptor A2a0306
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20404
Guanine deaminase0101
Chain A, Ferritin light chain5005
Microtubule-associated protein tau100010
caspase 7, apoptosis-related cysteine protease5005
progesterone receptor260026
67.9K protein6006
caspase-35005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
thyrotropin-releasing hormone receptor5005
vitamin D3 receptor isoform VDRA100010
mitogen-activated protein kinase 18008
survival motor neuron protein isoform d6006
Caspase-20011
ATPase family AAA domain-containing protein 56006
Ataxin-27007
interleukin 8150015
aldehyde dehydrogenase 1 family, member A1240024
G120012
cytochrome P450 2D68008
aryl hydrocarbon receptor130013
streptokinase A precursor0055
Dihydroxyacetone phosphate acyltransferase0002
Interferon beta150015
HLA class I histocompatibility antigen, B alpha chain 120012
30S ribosomal protein S60415
30S ribosomal protein S70415
50S ribosomal protein L150415
Cytochrome P450 3A40516
50S ribosomal protein L100415
50S ribosomal protein L110415
50S ribosomal protein L7/L120415
50S ribosomal protein L190415
50S ribosomal protein L10415
50S ribosomal protein L200415
50S ribosomal protein L270415
50S ribosomal protein L280415
50S ribosomal protein L290415
50S ribosomal protein L310415
50S ribosomal protein L31 type B0415
50S ribosomal protein L320415
50S ribosomal protein L330415
50S ribosomal protein L340415
50S ribosomal protein L350415
50S ribosomal protein L360415
30S ribosomal protein S100415
30S ribosomal protein S110415
30S ribosomal protein S120415
30S ribosomal protein S130415
30S ribosomal protein S160415
30S ribosomal protein S180415
30S ribosomal protein S190415
30S ribosomal protein S200415
30S ribosomal protein S20415
30S ribosomal protein S30415
30S ribosomal protein S40415
30S ribosomal protein S50415
30S ribosomal protein S80415
30S ribosomal protein S90415
50S ribosomal protein L130415
50S ribosomal protein L140415
50S ribosomal protein L160415
50S ribosomal protein L230415
30S ribosomal protein S150415
50S ribosomal protein L170415
50S ribosomal protein L210415
50S ribosomal protein L300415
50S ribosomal protein L60415
30S ribosomal protein S140415
30S ribosomal protein S170415
30S ribosomal protein S10415
50S ribosomal protein L180415
50S ribosomal protein L20415
50S ribosomal protein L30415
50S ribosomal protein L240415
50S ribosomal protein L40415
50S ribosomal protein L220415
50S ribosomal protein L50415
30S ribosomal protein S210415
50S ribosomal protein L250415
50S ribosomal protein L36 20415
Inositol hexakisphosphate kinase 1120012
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial120012
pregnane X receptor110011
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)8008
Caspase-77007
potassium voltage-gated channel subfamily H member 2 isoform d9009
caspase-37007
nuclear factor NF-kappa-B p105 subunit isoform 15005
cytochrome P450 3A4 isoform 1140014
Gamma-aminobutyric acid receptor subunit pi140014
Androgen receptor010010
Gamma-aminobutyric acid receptor subunit beta-1140014
Gamma-aminobutyric acid receptor subunit delta140014
Gamma-aminobutyric acid receptor subunit gamma-2140014
Gamma-aminobutyric acid receptor subunit alpha-5140014
Gamma-aminobutyric acid receptor subunit alpha-3140014
Gamma-aminobutyric acid receptor subunit gamma-1140014
Gamma-aminobutyric acid receptor subunit alpha-2140014
Gamma-aminobutyric acid receptor subunit alpha-4140014
Gamma-aminobutyric acid receptor subunit gamma-3140014
Gamma-aminobutyric acid receptor subunit alpha-6140014
Nuclear receptor ROR-gamma130013
Gamma-aminobutyric acid receptor subunit alpha-1140014
Gamma-aminobutyric acid receptor subunit beta-3140014
Gamma-aminobutyric acid receptor subunit beta-2140014
Peroxisome proliferator-activated receptor alpha1001
GABA theta subunit140014
Gamma-aminobutyric acid receptor subunit epsilon140014
P2Y purinoceptor 120202
Protein-arginine deiminase type-40808
Chain A, HADH2 protein100010
Chain B, HADH2 protein100010
GALC protein4004
Thrombopoietin2002
nonstructural protein 13003
serine/threonine-protein kinase mTOR isoform 13003
Solute carrier family 22 member 30203
Solute carrier family 22 member 30101
Sex hormone-binding globulin0033
Corticosteroid-binding globulin0404
Mineralocorticoid receptor 0224
C-8 sterol isomerase0101
Solute carrier organic anion transporter family member 1A10505
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sigma non-opioid intracellular receptor 10202
endonuclease IV4004
dopamine D1 receptor2002
peripheral myelin protein 22 isoform 14004
flap endonuclease 13003
M-phase phosphoprotein 84004
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 438008
Carbonic anhydrase 40405
Carbonic anhydrase0304
Carbonic anhydrase 150304
glp-1 receptor, partial9009
ATAD5 protein, partial5005
Fumarate hydratase4004
PPM1D protein2002
Smad32002
polyprotein4004
P531001
RPL19A0011
Spike glycoprotein0011
Replicase polyprotein 1ab0011
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a4004
ras-related protein Rab-9A4004
heat shock protein HSP 90-alpha isoform 20102
transactivating tegument protein VP16 [Human herpesvirus 1]0202
COUP transcription factor 2 isoform a0101
Transmembrane protease serine 20011
Glucose transporter0101
Hexose transporter 1 0101
Procathepsin L0112
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Solute carrier family 2, facilitated glucose transporter member 10101
Alpha-synuclein2507
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0101
Endothelial PAS domain-containing protein 10101
Angiotensin-converting enzyme 2 0011
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0001
LMP1 [Human herpesvirus 4]0002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
nuclear receptor coactivator 3 isoform a0101
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic0202
Thymidine kinase0101
Thymidylate synthase0102
Thymidine kinase0101
Deoxycytidine kinase0001
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
D(1A) dopamine receptor1001
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Thymidine kinase0101
Deoxynucleoside kinase0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE130013
Mitogen-activated protein kinase 140101
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK13003
Motilin receptor0112
Rap guanine nucleotide exchange factor 35005
Albumin0145
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB10607
60 kDa chaperonin0202
Chitinase B0101
ATP-dependent translocase ABCB10303
Low molecular weight phosphotyrosine protein phosphatase0101
Potassium voltage-gated channel subfamily H member 20404
Lanosterol 14-alpha demethylase0202
arylsulfatase A2002
Bloom syndrome protein isoform 17007
hexokinase-4 isoform 11001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor4004
glucokinase regulatory protein1001
Estrogen receptor0416
Steryl-sulfatase0101
Aromatase0101
Polyunsaturated fatty acid lipoxygenase ALOX150202
17-beta-hydroxysteroid dehydrogenase type 10203
Mu-type opioid receptor0328
5-hydroxytryptamine receptor 2B0202
Mu-type opioid receptor0415
Estrogen receptor beta0315
Ghrelin O-acyltransferase0202
neuropeptide S receptor isoform A3003
Monoglyceride lipase0101
14 kDa phosphohistidine phosphatase0101
Chain A, Dihydrofolate reductase0011
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
glucocerebrosidase2002
alpha-galactosidase2002
lysosomal alpha-glucosidase preproprotein4004
Thymidylate synthase0303
Aldo-keto reductase family 1 member B10204
Multidrug resistance associated protein0001
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
1-deoxy-D-xylulose 5-phosphate reductoisomerase0101
1-deoxy-D-xylulose 5-phosphate reductoisomerase0101
1-deoxy-D-xylulose 5-phosphate reductoisomerase0213
1-deoxy-D-xylulose 5-phosphate reductoisomerase0101
1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic0101
1-deoxy-D-xylulose 5-phosphate reductoisomerase 0101
Asialoglycoprotein receptor 10112
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor2002
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Excitatory amino acid transporter 40101
Glutathione reductase, mitochondrial0404
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Integrin beta-31012
Integrin alpha-IIb1012
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50224
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0202
Alpha-ketoglutarate-dependent dioxygenase FTO0202
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10202
Proton-coupled amino acid transporter 10101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
serine-protein kinase ATM isoform a1001
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
bromodomain adjacent to zinc finger domain 2B5005
transforming acidic coiled-coil-containing protein 30001
Carbonic anhydrase 120203
Plasma kallikrein0001
Carbonic anhydrase 30102
Macrophage migration inhibitory factor0202
Carbonic anhydrase 60304
Histamine H2 receptor0123
5-hydroxytryptamine receptor 1D0001
Histamine H1 receptor0134
Histamine H1 receptor0213
Carbonic anhydrase 5A, mitochondrial0305
Histamine H1 receptor0224
Carbonic anhydrase 70102
Histamine H2 receptor4015
Carbonic anhydrase0103
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 90405
Carbonic anhydrase 0103
Carbonic anhydrase0103
Carbonic anhydrase0103
Carbonic anhydrase 0103
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130102
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 40102
Carbonic anhydrase 130102
Histamine H4 receptor0123
Carboxylic ester hydrolase 0001
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0103
Histamine H3 receptor0123
Thymidine kinase 0101
importin subunit beta-1 isoform 12002
snurportin-12002
Vpr2002
Thymidine phosphorylase0001
Thymidine kinase0001
Chain A, membrane-associated prostaglandin E synthase-20101
Parkin3003
cytochrome P450 2D6 isoform 12002
cytochrome P450 2C9 precursor3003
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Solute carrier family 22 member 60404
Prostaglandin G/H synthase 1 0102
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0404
Cytochrome c oxidase subunit 20101
Epidermal growth factor receptor0101
Phospholipase A2, major isoenzyme0101
Prostaglandin G/H synthase 10405
Interleukin-80101
Androgen receptor0213
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 10101
Sodium-dependent dopamine transporter0101
Sodium- and chloride-dependent GABA transporter 10101
Thromboxane-A synthase 0101
Serum paraoxonase/arylesterase 10202
Indoleamine 2,3-dioxygenase 10101
Caspase-10102
Nitric oxide synthase, inducible0101
Substance-P receptor0101
Prostaglandin E2 receptor EP3 subtype0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 20415
Prostaglandin G/H synthase 2 0202
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G3003
Prostaglandin D2 receptor 0202
Prostaglandin G/H synthase 20303
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Solute carrier family 22 member 60303
Solute carrier family 22 member 70102
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0202
Solute carrier family 22 member 80506
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Solute carrier organic anion transporter family member 1B30405
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10405
histone deacetylase 9 isoform 33003
Chymotrypsinogen A0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Cationic amino acid transporter 30101
15-lipoxygenase, partial5005
Carboxylic ester hydrolase 0101
Glutaminyl-peptide cyclotransferase0101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Chain A, JmjC domain-containing histone demethylation protein 3A4004
PINK11001
Rap guanine nucleotide exchange factor 41001
Opioid receptor, delta 1b 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0011
Muscarinic acetylcholine receptor M20101
Translocator protein0011
Histidine decarboxylase0011
Proteinase-activated receptor 10112
Delta-type opioid receptor0203
Delta-type opioid receptor0315
Kappa-type opioid receptor0214
Kappa-type opioid receptor0214
Mu-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Delta-type opioid receptor0214
Kappa-type opioid receptor0214
Mu-type opioid receptor0215
Nociceptin receptor0101
5-hydroxytryptamine receptor 70303
Mu-type opioid receptor0101
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Amyloid-beta precursor protein0303
Cholesteryl ester transfer protein0101
Xanthine dehydrogenase/oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
Hydroxycarboxylic acid receptor 20112
Solute carrier family 2, facilitated glucose transporter member 90112
Nrf21001
Microphthalmia-associated transcription factor0001
hypothetical protein, conserved1001
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
caspase recruitment domain family, member 150101
glucose-6-phosphate 1-dehydrogenase isoform b0101
receptor-interacting serine/threonine-protein kinase 2 isoform 10101
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
Beta lactamase (plasmid)0101
WRN1001
Valosin-containing protein0101
microphthalmia-associated transcription factor isoform 90101
ubiquitin carboxyl-terminal hydrolase 2 isoform a4004
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
eukaryotic translation initiation factor 4E isoform 10101
muscleblind-like protein 1 isoform 12002
phosphoglycerate kinase1001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase0001
Solute carrier family 22 member 80203
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase0001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase TEM0102
Beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 80304
Estrogen receptor 10101
D(1A) dopamine receptor1001
fMet-Leu-Phe receptor0101
Cyclooxygenase-2 0101
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
luciferase0001
nuclear receptor subfamily 1, group I, member 22002
Fatty acid-binding protein, liver0101
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glutamine synthetase0011
Nociceptin receptor0011
Solute carrier organic anion transporter family member 1A40303
UDP-glucuronosyltransferase 1A90101
Transient receptor potential cation channel subfamily A member 10011
UDP-glucuronosyltransferase 1-60101
UDP-glucuronosyltransferase 1A1 0101
Canalicular multispecific organic anion transporter 10101
Pannexin-10101
Solute carrier family 22 member 120101
Solute carrier organic anion transporter family member 1C10101
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
Pannexin-10101
Solute carrier family 22 member 110203
Solute carrier family 22 member 70203
Trace amine-associated receptor 50022
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Pyridoxal kinase0001
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
C-terminal-binding protein 20101
Monocarboxylate transporter 20101
Solute carrier organic anion transporter family member 2A10101
Solute carrier family 22 member 10101
Solute carrier family 22 member 20101
Histidine-rich protein PFHRP-II0101
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D60202
Cytochrome P450 2D30101
Cytochrome P450 2D40101
Chain A, Cellular retinoic acid-binding protein 20011
Chain A, Cellular retinoic acid-binding protein 20011
Aldo-keto reductase family 1 member B100002
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Disintegrin and metalloproteinase domain-containing protein 172002
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain A, Breast cancer type 1 susceptibility protein1001
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
NPYLR7B0011
tumor necrosis factor1001
caspase-1 isoform alpha precursor1001
Riboflavin-binding protein0112
Caspase-71001
DNA-directed RNA polymerase subunit beta0101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Nuclear receptor subfamily 1 group I member 20011
NH(3)-dependent NAD(+) synthetase0202
Cytochrome P450 2B60011
Arylacetamide deacetylase0102
Solute carrier organic anion transporter family member 1A20101
Glutathione S-transferase omega-10101
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0102
DNA-directed RNA polymerase subunit beta0101
Taste receptor type 2 member 160012
exodeoxyribonuclease V subunit RecD0202
exodeoxyribonuclease V subunit RecB0202
exodeoxyribonuclease V subunit RecC0202
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0202
Dihydrofolate reductase0304
Endothelin-1 receptor0202
Protease 0112
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 20112
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Protein argonaute-20011
Transcriptional activator protein LasR0101
Endothelin-1 receptor0101
Protein arginine N-methyltransferase 60101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
Muscarinic acetylcholine receptor M20101
72 kDa type IV collagenase0101
Stromelysin-10101
Multidrug transporter MdfA0101
Alpha-1B adrenergic receptor0101
Neutrophil collagenase0101
Alpha-1D adrenergic receptor0101
Alpha-1A adrenergic receptor0101
Collagenase 30101
Cannabinoid receptor 10101
Integrase 0101
Cereblon isoform 40202
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0416
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
Estrogen receptor0011
Estrogen receptor beta0011
Delta0101
Cycloeucalenol cycloisomerase0101
Sterol-8,7-isomerase0101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
cytochrome P450 2C19 precursor1001
Dihydrofolate reductase 0102
Dihydrofolate reductase 0101
Dihydrofolate reductase0202
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0101
Dihydrofolate reductase0202
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0102
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase 0202
Dihydrofolate reductase 0101
Dihydrofolate reductase0102
Dihydrofolate reductase 0101
Chain A, Uracil-DNA Glycosylase0101
Urease subunit alpha0101
Urease subunit beta0101
Hsf1 protein0011
twin arginine protein translocation system - TatA protein0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]