An organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H).
| Member | Definition | Role |
|---|
| 2-(2-phenoxyethylsulfonyl)-1H-benzimidazole | | 2-(2-phenoxyethylsulfonyl)-1H-benzimidazole |
| 4-(4-chlorophenyl)sulfinyl-6-(methoxymethyl)-2-methylpyrimidine | | 4-(4-chlorophenyl)sulfinyl-6-(methoxymethyl)-2-methylpyrimidine |
| 5-hydroxymethylomeprazole | A sulfoxide that is omeprazole in which one of the methyl hydrogens at position 5 on the pyridine ring is substituted by a hydroxy group. | 5'-hydroxyomeprazole |
| 6-methylsulfinylhexyl isothiocyanate | | 1-isothiocyanato-6-(methylsulfinyl)hexane |
| ajoene | | (E)-Ajoene |
| albendazole sulfoxide | | albendazole S-oxide |
| allicin | | allicin |
| alyssin | | 1-isothiocyanato-5-(methylsulfinyl)pentane |
| cenicriviroc | A member of the class of benzazocines that is (5Z)-1,2,3,4-tetrahydro-1-benzazocine which is substituted by a 2-methylpropyl, N-{4-[(S)-(1-propyl-1H-imidazol-5-yl)methanesulfinyl]phenyl}carboxamide and 4-(2-butoxyethoxy)phenyl groups at positions 1, 5 and 8, respectively. It is a potent chemokine 2 and 5 receptor antagonist currently in development for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis (NASH). | cenicriviroc |
| cimetidine sulfoxide | | cimetidine S-oxide |
| d-biotin-d-sulfoxide | A sulfoxide that is the S-oxide of biotin. | biotin sulfoxide |
| dexlansoprazole | | dexlansoprazole |
| dimethyl sulfoxide | A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. | dimethyl sulfoxide |
| diphenyl sulfoxide | | Diphenyl sulfoxide |
| esomeprazole magnesium | | magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]benzimidazol-1-ide |
| fensulfothion | | fensulfothion |
| fipronil | A member of the class of pyrazoles that is 1H-pyrazole that is substituted at positions 1, 3, 4, and 5 by 2,6-dichloro-4-(trifluoromethyl)phenyl, cyano, (trifluoromethyl)sulfinyl, and amino groups, respectively. | 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile |
| fulvestrant | A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer. | fulvestrant |
| glucoraphanin | A thia-glucosinolic acid that is glucoerucin in which the sulfur atom of the methyl thioether group has been oxidised to the corresponding sulfoxide. | glucoraphanin |
| iberin | An isothiocyanate that is 1-isothiocyanatopropane in which a hydrogen at position 3 has been replaced by a methylsulfinyl group. A glucosinolate hydrolysis product found in many members of the Brassicaceae family, it is a quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa. | iberin |
| ilaprazole | | ilaprazole |
| lansoprazole | | lansoprazole |
| mesoridazine | A phenothiazine substituted at position 2 (para to the S atom) by a methylsulfinyl group, and on the nitrogen by a 2-(1-methylpiperidin-2-yl)ethyl group. | mesoridazine |
| methiocarb sulfoxide | A carbamate ester obtained by the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfinyl)phenol with the carboxy group of methylcarbamic acid. It is a metabolite of the pesticide methiocarb. | methiocarb-sulfoxide |
| methyl phenyl sulfoxide | A sulfoxide resulting from the formal oxidation of the sulfur atom of thioanisole. | (methylsulfinyl)benzene |
| modafinil | A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group. | 2-[(diphenylmethyl)sulfinyl]acetamide |
| omeprazole | A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5. | 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; 6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-benzimidazole |
| omeprazole | | 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; 6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-benzimidazole |
| omeprazole magnesium | | magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]benzimidazol-1-ide |
| omeprazole sulfone | | Omeprazole sulfone |
| oxfendazole | A member of the class of benzimidazoles that is fenbendazole in which the sulfur has been oxidised to the corresponding sulfoxide. | oxfendazole |
| pantoprazole | A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2. | pantoprazole |
| rabeprazole | | rabeprazole |
| ro 106-9920 | | 6-(benzenesulfinyl)tetrazolo[1,5-b]pyridazine |
| sb 203580 | A member of the class of imidazoles carrying 4-methylsulfinylphenyl, 4-pyridyl and 4-fluorophenyl substituents at positions 2, 4 and 5 respectively. An inhibitor of mitogen-activated protein kinase. | SB 203580 |
| sulfinpyrazone | | sulfinpyrazone |
| sulforaphane | An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen. | sulforaphane |
| sulindac | A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions. | sulindac |
| sulmazole | An imidazopyridine that is 1H-imidazo[4,5-b]pyridine which is substituted at position 2 by a 2-methoxy-4-(methylsulfinyl)phenyl group. An A1 adenosine receptor antagonist, it was formerly used as a cardiotonic agent. | sulmazole |
| ustiloxin b | A heterodetic cyclic peptide with formula C26H39N5O12S produced by Ustilaginoidea virens fungi. It is an inhibitor of microtubule assembly. | ustiloxin B |