Any member of the class of imidazoles carrying at least one amino substituent.
ChEBI ID: 22512
Member | Definition | Role |
---|---|---|
2-benzimidazolylguanidine | 2-Benzimidazolylguanidine | |
4-aminoimidazole | An aminoimidazole that is 1H-imidazole substituted by an amino group at position 4. | 4-aminoimidazole |
acadesine | A 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects. | acadesine |
aica ribonucleotide | A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative. | AICA ribonucleotide |
aminoimidazole carboxamide | An aminoimidazole in which the amino group is at C-5 with a carboxamido group at C-4. | 5-aminoimidazole-4-carboxamide |
aminoimidazole ribotide | A 1-(phosphoribosyl)imidazole that is 5-aminoimidazole in which the proton at position 1 has been replaced by a 5-phospho-beta-D-ribofuranosyl group. | 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole |
carboxyaminoimidazole ribotide | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylic acid |
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 174 (8.76) | 18.7374 |
1990's | 212 (10.67) | 18.2507 |
2000's | 616 (31.00) | 29.6817 |
2010's | 857 (43.13) | 24.3611 |
2020's | 128 (6.44) | 2.80 |
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 58 (1.63%) | 5.53% |
Reviews | 94 (2.64%) | 6.00% |
Case Studies | 25 (0.70%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 3,379 (95.02%) | 84.16% |