Any dicarboxylic acid that contains four carbon atoms.
ChEBI ID: 66873
Member | Definition | Role |
---|---|---|
2-butynedioic acid | An acetylenic compound that is acetylene in which the hydrogens are replaced by carboxy groups. | butynedioic acid |
2-thiomalic acid | thiomalic acid | |
3-hydroxyaspartic acid | A hydroxy-amino acid that is aspartic acid in which one of the methylene hydrogens has been replaced by a hydroxy group. | 3-hydroxyaspartic acid |
dihydroxyfumarate | A 2-hydroxydicarboxylic acid consisting of fumaric acid having two hydroxy groups at the 2- and 3-positions. | dihydroxyfumaric acid |
iminoaspartic acid | A succinic acid derivative having an imino group at the 2-position. | iminoaspartic acid |
malic acid | A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group. | malic acid |
methylmalonic acid | A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group. | methylmalonic acid |
oxaloacetic acid | An oxodicarboxylic acid that is succinic acid bearing a single oxo group. | oxaloacetic acid |
succinic acid | An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle. | succinic acid |
ureidosuccinic acid | An N-carbamoylamino acid that is aspartic acid with one of its amino hydrogens replaced by a carbamoyl group. | N-carbamoylaspartic acid |
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 1,677 (19.86) | 18.7374 |
1990's | 1,218 (14.43) | 18.2507 |
2000's | 2,011 (23.82) | 29.6817 |
2010's | 2,622 (31.06) | 24.3611 |
2020's | 914 (10.83) | 2.80 |
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 148 (1.59%) | 5.53% |
Reviews | 429 (4.61%) | 6.00% |
Case Studies | 404 (4.35%) | 4.05% |
Observational | 11 (0.12%) | 0.25% |
Other | 8,306 (89.33%) | 84.16% |