Page last updated: 2024-08-05 10:41:32

C4-dicarboxylic acid

Any dicarboxylic acid that contains four carbon atoms.

ChEBI ID: 66873

Members (10)

MemberDefinitionRole
2-butynedioic acidAn acetylenic compound that is acetylene in which the hydrogens are replaced by carboxy groups.butynedioic acid
2-thiomalic acidthiomalic acid
3-hydroxyaspartic acidA hydroxy-amino acid that is aspartic acid in which one of the methylene hydrogens has been replaced by a hydroxy group.3-hydroxyaspartic acid
dihydroxyfumarateA 2-hydroxydicarboxylic acid consisting of fumaric acid having two hydroxy groups at the 2- and 3-positions.dihydroxyfumaric acid
iminoaspartic acidA succinic acid derivative having an imino group at the 2-position.iminoaspartic acid
malic acidA 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.malic acid
methylmalonic acidA dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.methylmalonic acid
oxaloacetic acidAn oxodicarboxylic acid that is succinic acid bearing a single oxo group.oxaloacetic acid
succinic acidAn alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.succinic acid
ureidosuccinic acidAn N-carbamoylamino acid that is aspartic acid with one of its amino hydrogens replaced by a carbamoyl group.N-carbamoylaspartic acid

Research

Studies (8,442)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19901,677 (19.86)18.7374
1990's1,218 (14.43)18.2507
2000's2,011 (23.82)29.6817
2010's2,622 (31.06)24.3611
2020's914 (10.83)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials148 (1.59%)5.53%
Reviews429 (4.61%)6.00%
Case Studies404 (4.35%)4.05%
Observational11 (0.12%)0.25%
Other8,306 (89.33%)84.16%