Page last updated: 2024-08-05 12:16:25

enamine

An amine RNR'R'' where R has a double bond adjacent to the amine nitrogen.

ChEBI ID: 47989

Members (11)

MemberDefinitionRole
2-amino-4-(3-cyclohexen-1-yl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydrochromene-3-carbonitrileA member of the class of chromenes that is 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydrochromene carrying additional amino, cyano and 3-cyclohexen-1-yl substituents at positions 2, 3 and 4 respectively.2-amino-4-(3-cyclohexen-1-yl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydrochromene-3-carbonitrile
bacillaeneA polyene antibiotic obtained from Bacillus subtilis 168 that is active against a broad spectrum of bacteria. It is notoriously unstable.bacillaene
dehydroalanineA 2,3-dehydroamino acid that is alanine which has been dehydrogenated to introduce a double bond between positions 2 and 3.2-aminoacrylic acid; 2-ammonioprop-2-enoate
dehydrobutyrineA 2,3-dehydroamino acid resulting from the formal elimination of water from the side-chain of threonine.(Z)-2-aminobutenoic acid
diaziquoneA 1,4-benzoquinone that is substituted at positions 2 and 5 have been replaced by aziridin-1-yl groups and at positions 3 and 6 by (ethoxycarbonyl)amino groups.diaziquone
flupyradifuroneA tertiary amino compound that is ammonia in which the nitrogens have been replaced by (6-chloropyridin-3-yl)methyl, 2,2-difluoroethyl, and 5-oxo-2,5-dihydrofuran-3-yl groups, respectively. A nicotinic acetylcholine receptor (AChR) agonist, it is used as an insecticide to control sucking pests in a variety of crops.flupyradifurone
Methyl 2-cyano-3-(dimethylamino)acrylateMethyl 2-cyano-3-(dimethylamino)acrylate
neticonazoleAn enamine that is ethene which is substituted at positions 1, 1, and 2 by o-pentoxyphenyl, 1H-imidazol-1-yl, and methylthio groups, respectively (the E isomer). An inhibitor of P450-dependent C-14alpha-demethylation of lanosterol (preventing conversion to ergosterol and inhibiting cell wall synthesis in fungi), it is used in Japan (generally as the corresponding hydrochloride salt) as an antifungal drug for the treatment of superficial skin infections.neticonazole
nsc 224070A member of the class of 1,4-benzoquinones that is 1,4-benzoquinone in which the hydrogens at positions 2 and 5 have been replaced by aziridin-1-yl groups while the hydrogens at positions 3 and 6 have been replaced by (2-hydroxyethyl)amino groups.2,5-bis(2-hydroxyethylamino)-3,6-diaziridinylbenzoquinone
SL-327A nitrile that is acrylonitrile in which the hydrogen attached to the same carbon as the cyano group has been replaced by an o-(trifluoromethyl)phenyl group, while the remaining hydrogens of the ethenyl group have been replaced by amino and (4-aminophenyl)sulfanyl groups. The configuration of the double bond is not specified. It is an inhibitor of MEK1 and MEK2.SL-327
u 0126An aryl sulfide that is (2Z,3Z)-bis[amino(sulfanyl)methylidene]butanedinitrile in which the sulfanyl hydrogens are replaced by 2-aminophenyl groups. An inhibitor of mitogen-activated protein kinase that also exhibits anti-cancer properties.U0126

Research

Studies (3,294)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990133 (4.04)18.7374
1990's110 (3.34)18.2507
2000's1,451 (44.05)29.6817
2010's1,398 (42.44)24.3611
2020's202 (6.13)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials25 (0.74%)5.53%
Reviews28 (0.83%)6.00%
Case Studies8 (0.24%)4.05%
Observational0 (0.00%)0.25%
Other3,317 (98.19%)84.16%