Any herbicide composed of urea or substituted urea substructure.
ChEBI ID: 188147
| Member | Definition | Class |
|---|---|---|
| diuron | A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group. | diuron |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 491 (33.61) | 18.7374 |
| 1990's | 121 (8.28) | 18.2507 |
| 2000's | 355 (24.30) | 29.6817 |
| 2010's | 391 (26.76) | 24.3611 |
| 2020's | 103 (7.05) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 13 (0.85%) | 6.00% |
| Case Studies | 2 (0.13%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,506 (99.01%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| AR protein | Homo sapiens (human) | Potency | 31.2978 | 5 | 9 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 41.1688 | 3 | 7 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 25.7877 | 2 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 38.4531 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 0.2239 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 61.9213 | 4 | 4 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 68.3804 | 2 | 2 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 54.1734 | 2 | 2 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 68.5896 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 37.3091 | 3 | 9 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 54.7509 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 60.9441 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 22.0041 | 2 | 2 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 19.4938 | 2 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 4.1095 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 27.3060 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 76.7241 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Photosystem II protein D1 | Spinacia oleracea (spinach) | IC50 | 1.0849 | 2 | 2 |