An agent that prevents blood clotting.
| Member | Definition | Class |
|---|
| 3-methylquercetin | A monomethoxyflavone that is quercetin in which the hydroxy group at position 3' is replaced by a methoxy group. | isorhamnetin |
| acenocoumarol | A hydroxycoumarin that is warfarin in which the hydrogen at position 4 of the phenyl substituent is replaced by a nitro group. | acenocoumarol |
| acetylphenylalanyl-prolyl-boroarginine | A C-terminal boronic acid petide that is N-acetyl-D-phenylalanyl-L-prolyl-L-arginine in which the C-termnal carboxy group has been replaced by a borono (-B(OH)2) group. A thrombin (Factor IIa) inhibitor, thereby acting as an anticoagulant. | Ac-(D)Phe-Pro-boroArg-OH |
| alprostadil | | prostaglandin E1 |
| anisindione | A cyclic beta-diketone consisting of indane-1,3-dione having a 4-methoxyphenyl substituent at the 4-position. | anisindione |
| apixaban | A pyrazolopyridine that is 7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide substituted at position 1 by a 4-methoxyphenyl group and at position 6 by a 4-(2-oxopiperidin-1-yl)phenyl group. It is used for the prevention and treatment of thromboembolic diseases. | apixaban |
| aspirin | A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity. | acetylsalicylic acid |
| astaxanthine | A carotenone that consists of beta,beta-carotene-4,4'-dione bearing two hydroxy substituents at positions 3 and 3' (the 3S,3'S diastereomer). A carotenoid pigment found mainly in animals (crustaceans, echinoderms) but also occurring in plants. It can occur free (as a red pigment), as an ester, or as a blue, brown or green chromoprotein. | astaxanthin |
| atromentin | A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxycyclohexa-2,5-diene-1,4-dione which is substituted by a 4-hydroxyphenyl group at positions 3 and 6. It is a mushroom pigment isolated from several fungi species and acts as a smooth muscle stimulant, and exhibits anticoagulant, antibacterial and antineoplastic properties. | atromentin |
| betrixaban | A secondary carboxamide obtained by formal condensation of the carboxy group of 4-(N,N-dimethylcarbamimidoyl)benzoic acid with the amino group of 2-amino-N-(5-chloropyridin-2-yl)-5-methoxybenzamide. A synthetic anticoagulant compound that targets activated factor Xa in the coagulation cascade. | betrixaban |
| bivalirudin | A synthetic peptide of 20 amino acids, comprising D-Phe, Pro, Arg, Pro, Gly, Gly, Gly, Gly, Asn, Gly, Asp, Phe, Glu, Glu, Ile, Pro, Glu, Glu, Tyr, and Leu in sequence. A congener of hirudin (a naturally occurring drug found in the saliva of the medicinal leech), it a specific and reversible inhibitor of thrombin, and is used as an anticoagulant. | bivalirudin |
| bl 4162a | A 1,5-dihydroimidazo[2,1-]quinazoline having an oxo substituent at the 2-position and chloro substituents at the 6- and 7-positions. | anagrelide |
| cilostazol | A lactam that is 3,4-dihydroquinolin-2(1H)-one in which the hydrogen at position 6 is substituted by a 4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy group. | cilostazol |
| clopidogrel | A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group, the methylene hydrogen of which is replaced by a methoxycarbonyl group (the S enantiomer). A P2Y12 receptor antagonist, it is used to inhibit blood clots and prevent heart attacks. | clopidogrel |
| d-alpha tocopherol | An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. | (R,R,R)-alpha-tocopherol |
| dabigatran | An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-beta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism. | dabigatran |
| dabigatran etexilate | An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl N-pyridin-2-yl-beta-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism. | dabigatran etexilate |
| dabigatran etexilate | An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl N-pyridin-2-yl-beta-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism. | dabigatran etexilate |
| dicumarol | A hydroxycoumarin that is methane in which two hydrogens have each been substituted by a 4-hydroxycoumarin-3-yl group. Related to warfarin, it has been used as an anticoagulant. | dicoumarol |
| dieckol | A phlorotannin isolated from a brown alga Ecklonia cava which exhibits antioxidant, hepatoprotective and anticoagulant activities. | dieckol |
| edetic acid | | ethylenediaminetetraacetic acid |
| edoxaban | A monocarboxylic acid amide that is used (as its tosylate monohydrate) for the treatment of deep vein thrombosis and pulmonary embolism. | edoxaban |
| eptifibatide | A synthetic homodetic cyclic peptide comprising N(alpha)-(3-sulfanylpropanoyl)homoarginyl, glycyl, aspartyl, tryptophyl, prolyl and cysteinamide residues connected in sequence and cyclised via a disulfide bond. Derived from a protein found in the venom of the southeastern pygmy rattlesnake, Sistrurus miliarus barbouri, eptifibatide is an anti-coagulant that inhibits platelet aggregation by selectively blocking the platelet glycoprotein IIb/IIIa receptor, so preventing the binding of fibrinogen, von Willebrand factor, and other adhesive ligands. It is used in the management of unstable angina and in patients undergoing coronary angioplasty and stenting procedures. | eptifibatide |
| fondaparinux | A synthetic pentasaccharide which, apart from the O-methyl group at the reducing end of the molecule, consists of monomeric sugar units which are identical to a sequence of five monomeric sugar units that can be isolated after either chemical or enzymatic cleavage of the polymeric glycosaminoglycans heparin and heparan sulfate. | fondaparinux |
| ginsenoside rg2 | A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. | ginsenoside Rg2 |
| melagatran | A member of the class of azetidines that is (2S)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2R)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group. | melagatran |
| pd 0348292 | A member of the class of pyrrolidines that is (2R,4R)-N(1)-(p-chlorophenyl)-4-methoxypyrrolidine-1,2-dicarboxamide in which the nitrogen of the 2-carbamoyl group has been substituted by a 2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl group. It is a synthetic organic anticoagulant compound that targets activated factor Xa in the coagulation cascade. | eribaxaban |
| phenindione | | phenindione |
| phenprocoumon | A hydroxycoumarin that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenylpropyl group. | phenprocoumon |
| plavix | | clopidogrel sulfate |
| plumbagin | A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively. | plumbagin |
| rivaroxaban | A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery. | rivaroxaban |
| sodium citrate, anhydrous | The trisodium salt of citric acid. | sodium citrate |
| suberosin | A member of the class of coumarins in which the coumarin ring is substituted at positions 6 and 7 by a 3-methylbut-2-en-1-yl group and a methoxy group, respectively. A natural product found in Citropsis articulata. | suberosin |
| ticlopidine | A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group. | ticlopidine |
| tirofiban | A member of the class of piperidines that is L-tyrosine in which a hydrogen attached to the amino group is replaced by a butylsulfonyl group and in which the hydrogen attached to the phenolic hydroxy group is replaced by a 4-(piperidin-4-yl)butyl group. | tirofiban |
| troglitazone | | troglitazone |
| ximelagatran | A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted into the corresponding amidoxime. A prodrug for melagatran, ximelagatran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage. | ximelagatran (hydroxylamine form); ximelagatran |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 24.1724 | 1 | 4 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 31.0125 | 3 | 5 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 43.0431 | 1 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 20.4928 | 1 | 8 |
| AR protein | Homo sapiens (human) | Potency | 19.4989 | 11 | 44 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 26.2567 | 2 | 3 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 7.5686 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 6.3657 | 2 | 5 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 86.2885 | 1 | 3 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 22.1060 | 1 | 2 |
| Caspase-7 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 23.1089 | 3 | 12 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 8.4737 | 2 | 9 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 20.8042 | 1 | 4 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 46.6692 | 2 | 5 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 14.9425 | 1 | 3 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 30.7369 | 1 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 24.8068 | 1 | 8 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 0.1119 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 27.4709 | 1 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 30.7369 | 1 | 3 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 63.3425 | 1 | 3 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 5.0199 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 19.9179 | 1 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 4.9363 | 1 | 8 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 20.0244 | 1 | 6 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 0.3981 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 17.3831 | 2 | 13 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 15.0190 | 1 | 9 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 35.0933 | 1 | 3 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 54.5388 | 1 | 2 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 23.2600 | 1 | 4 |
| dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 12.5893 | 1 | 1 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 21.5333 | 11 | 42 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 15.6696 | 3 | 7 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 22.8389 | 8 | 40 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 12.6405 | 1 | 10 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 15.3602 | 4 | 19 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 39.1329 | 3 | 4 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 33.1734 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 4.9363 | 1 | 8 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 17.0407 | 1 | 7 |
| geminin | Homo sapiens (human) | Potency | 13.0125 | 2 | 6 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 19.1294 | 2 | 7 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 18.6231 | 1 | 2 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 0.3548 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 20.6431 | 3 | 8 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 22.6854 | 1 | 6 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 1.4581 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 13.6996 | 1 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 5.2276 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 31.0895 | 2 | 5 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 14.6604 | 2 | 10 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 34.0908 | 1 | 4 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 20.2361 | 2 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 42.8800 | 1 | 4 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 4.9363 | 1 | 8 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 50.1187 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 6.3106 | 1 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 0.4611 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 1.4581 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 4.9363 | 1 | 16 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 12.7781 | 1 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 8.0581 | 1 | 5 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 8.0581 | 1 | 5 |
| Interferon beta | Homo sapiens (human) | Potency | 5.2056 | 3 | 13 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 5.9119 | 1 | 5 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 31.6228 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 23.3923 | 3 | 9 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 11.2202 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 1.0000 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 13.5511 | 2 | 10 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 8.6378 | 3 | 6 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 2.2387 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 9.3914 | 1 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 17.9008 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 17.4813 | 3 | 11 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 32.0269 | 1 | 4 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 8.4127 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 9.7535 | 2 | 9 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 22.4302 | 3 | 14 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 66.8968 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 21.1892 | 1 | 2 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 6.0515 | 4 | 11 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 19.0884 | 3 | 7 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 35.4813 | 1 | 1 |
| polyprotein | Zika virus | Potency | 33.1734 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 6.7740 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 11.7768 | 1 | 3 |
| PPM1D protein | Homo sapiens (human) | Potency | 0.0829 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 26.1427 | 3 | 7 |
| progesterone receptor | Homo sapiens (human) | Potency | 15.0693 | 2 | 5 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 2 |
| RAF proto-oncogene serine/threonine-protein kinase isoform b | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 14.0020 | 2 | 15 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 23.7781 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 27.9444 | 2 | 12 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 12.1872 | 3 | 10 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 15.5646 | 2 | 5 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 15.5646 | 2 | 5 |
| snurportin-1 | Homo sapiens (human) | Potency | 1.4581 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 23.4120 | 1 | 6 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 11.7954 | 1 | 4 |
| TDP1 protein | Homo sapiens (human) | Potency | 16.8732 | 2 | 19 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 79.4328 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 12.5610 | 2 | 4 |
| Thrombopoietin | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 21.5397 | 3 | 9 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 25.6751 | 5 | 15 |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 31.9479 | 1 | 5 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 25.1555 | 2 | 6 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 17.5626 | 2 | 4 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 12.3395 | 1 | 3 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 22.6854 | 1 | 6 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 2.0450 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 6.3000 | 1 | 1 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 8.3000 | 1 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 2.4000 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 1.3120 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.8350 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 2.0450 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 6.3000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 5,000.0000 | 1 | 1 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 5,000.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 5.2080 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 2.9430 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Sus scrofa (pig) | IC50 | 95.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.2080 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2.9430 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.2080 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2.9430 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 0.3820 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.1430 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 0.3040 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.1390 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 1.1750 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.1710 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 3.0000 | 1 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 10.5000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | Ki | 4.8000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 2.0700 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 9.5000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | Ki | 10.9000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 18.0500 | 2 | 2 |
| Angiotensin-converting enzyme | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| ATP phosphoribosyltransferase | Mycobacterium tuberculosis H37Rv | Ki | 60.0000 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 103.2714 | 1 | 7 |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | IC50 | 1.2850 | 1 | 1 |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | IC50 | 1.2850 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 4.3400 | 1 | 1 |
| Beta-lactamase | Bacillus anthracis | IC50 | 1,060.0000 | 1 | 1 |
| Beta-lactamase | Pseudomonas aeruginosa | IC50 | 27.9000 | 1 | 1 |
| Beta-lactamase VIM-1 | Pseudomonas aeruginosa | IC50 | 9.3000 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 251.1050 | 2 | 2 |
| Beta-secretase 1 | Homo sapiens (human) | Ki | 1.5000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 65.2694 | 7 | 17 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 21.1667 | 2 | 3 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 6 |
| Carbonic anhydrase | Candida albicans SC5314 | Ki | 39.1000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 2,710.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 2,516.6667 | 3 | 3 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 0.1374 | 2 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 580.4850 | 2 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 1,598.0880 | 5 | 5 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 0.1560 | 2 | 2 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 1,670.0000 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 0.0044 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 4,930.0000 | 1 | 1 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 0.0112 | 1 | 1 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 34.0000 | 2 | 2 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | IC50 | 0.2710 | 10 | 10 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | IC50 | 0.3007 | 9 | 9 |
| Chain A, Activated Factor Xa Heavy Chain | Homo sapiens (human) | Ki | 0.0004 | 1 | 1 |
| Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) | Homo sapiens (human) | Ki | 0.0001 | 1 | 1 |
| Chain H, Prothrombin | Homo sapiens (human) | Ki | 0.0040 | 1 | 2 |
| Cholinesterase | Homo sapiens (human) | IC50 | 0.0026 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 3.3000 | 1 | 1 |
| Coagulation factor X | Homo sapiens (human) | IC50 | 2.5502 | 20 | 22 |
| Coagulation factor X | Homo sapiens (human) | Ki | 0.5293 | 18 | 29 |
| Coagulation factor X | Oryctolagus cuniculus (rabbit) | Ki | 0.0002 | 1 | 1 |
| Coagulation factor XI | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Coagulation factor XII | Homo sapiens (human) | IC50 | 33.0000 | 1 | 2 |
| Cruzipain | Trypanosoma cruzi | IC50 | 211.5000 | 2 | 2 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 1.4130 | 2 | 2 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 2.5600 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 1.8605 | 2 | 2 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 2.3600 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 3.0835 | 2 | 2 |
| Cytochrome P450 2B6 | Homo sapiens (human) | IC50 | 0.4050 | 2 | 2 |
| Cytochrome P450 2B6 | Homo sapiens (human) | Ki | 0.9000 | 2 | 3 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 5.3339 | 2 | 2 |
| Cytochrome P450 2C19 | Homo sapiens (human) | Ki | 34.8667 | 2 | 3 |
| Cytochrome P450 2C8 | Homo sapiens (human) | Ki | 26.3500 | 3 | 4 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 9.2200 | 3 | 5 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 1.2500 | 2 | 2 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 181.4309 | 3 | 3 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 21.8000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | IC50 | 17.3000 | 1 | 2 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Francisella tularensis subsp. tularensis SCHU S4 | IC50 | 47.0000 | 1 | 1 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 5.0000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Eyes absent homolog 2 | Homo sapiens (human) | IC50 | 386.2500 | 4 | 4 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Ki | 2,064.0000 | 2 | 2 |
| Forkhead box protein M1 | Homo sapiens (human) | IC50 | 122.4000 | 1 | 1 |
| Forkhead box protein M1 | Homo sapiens (human) | Ki | 0.0520 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | Ki | 0.0390 | 1 | 1 |
| Gag-Pol polyprotein | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | Ki | 1.0000 | 1 | 1 |
| Gag-Pol polyprotein | Human immunodeficiency virus type 2 (ISOLATE ROD) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.3500 | 1 | 1 |
| Glutathione hydrolase 1 proenzyme | Homo sapiens (human) | IC50 | 36.0000 | 1 | 1 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 0.5000 | 1 | 1 |
| Histone acetyltransferase KAT2B | Homo sapiens (human) | IC50 | 50.0000 | 3 | 3 |
| Histone acetyltransferase p300 | Homo sapiens (human) | IC50 | 15.5000 | 4 | 4 |
| Indoleamine 2,3-dioxygenase 1 | Mus musculus (house mouse) | IC50 | 61.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | IC50 | 4.5000 | 1 | 1 |
| Inositol hexakisphosphate kinase 2 | Homo sapiens (human) | IC50 | 0.5000 | 1 | 1 |
| Inositol polyphosphate multikinase | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 166.6667 | 2 | 3 |
| Integrin alpha-5 | Homo sapiens (human) | IC50 | 300.0000 | 2 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | IC50 | 3.3126 | 28 | 33 |
| Integrin alpha-V | Homo sapiens (human) | IC50 | 113.8352 | 6 | 6 |
| Integrin beta-1 | Homo sapiens (human) | IC50 | 300.0000 | 2 | 2 |
| Integrin beta-3 | Homo sapiens (human) | IC50 | 20.3161 | 34 | 39 |
| Integrin beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.1300 | 1 | 1 |
| Integrin subunit alpha 2b | Rattus norvegicus (Norway rat) | IC50 | 0.1300 | 1 | 1 |
| M-phase inducer phosphatase 1 | Homo sapiens (human) | IC50 | 0.7000 | 1 | 1 |
| M-phase inducer phosphatase 2 | Homo sapiens (human) | IC50 | 3.1000 | 1 | 1 |
| Metallo-beta-lactamase VIM-13 | Pseudomonas aeruginosa | IC50 | 252.6000 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 2.8320 | 1 | 2 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 13.2000 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 13.2000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 14 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 8.1000 | 1 | 1 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 25.3000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 87.4143 | 1 | 7 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| NAD | Homo sapiens (human) | IC50 | 0.2585 | 7 | 8 |
| NAD | Rattus norvegicus (Norway rat) | Ki | 0.0010 | 1 | 1 |
| Nicotinate phosphoribosyltransferase | Homo sapiens (human) | Ki | 0.0005 | 1 | 1 |
| Oligo-1,6-glucosidase IMA1 | Saccharomyces cerevisiae S288C | IC50 | 160.0000 | 1 | 1 |
| P2Y purinoceptor 12 | Homo sapiens (human) | IC50 | 2.4000 | 1 | 1 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | IC50 | 70.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | IC50 | 1.0300 | 6 | 6 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Ki | 0.3168 | 5 | 5 |
| Plasminogen | Homo sapiens (human) | IC50 | 5.3733 | 2 | 3 |
| Plasminogen | Homo sapiens (human) | Ki | 1.3983 | 3 | 3 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 20.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 8.9000 | 2 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 1.8000 | 1 | 1 |
| Proprotein convertase subtilisin/kexin type 7 | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| Prostacyclin receptor | Homo sapiens (human) | Ki | 2.6125 | 3 | 4 |
| Prostaglandin E2 receptor EP1 subtype | Mus musculus (house mouse) | Ki | 0.0375 | 3 | 4 |
| Prostaglandin E2 receptor EP2 subtype | Mus musculus (house mouse) | Ki | 0.0478 | 3 | 4 |
| Prostaglandin E2 receptor EP3 subtype | Mus musculus (house mouse) | Ki | 0.0050 | 3 | 3 |
| Prostaglandin E2 receptor EP4 subtype | Mus musculus (house mouse) | Ki | 0.0032 | 3 | 4 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 337.1452 | 10 | 10 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 1,813.8445 | 37 | 40 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | Ki | 62.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 2,018.7250 | 5 | 6 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 907.5235 | 24 | 26 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 523.7468 | 22 | 22 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Ki | 52.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | IC50 | 1,500.0000 | 1 | 2 |
| Prostaglandin-H2 D-isomerase | Mus musculus (house mouse) | IC50 | 1,500.0000 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | IC50 | 1.0000 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | Ki | 0.7002 | 4 | 4 |
| Prothrombin | Homo sapiens (human) | IC50 | 1.9735 | 24 | 26 |
| Prothrombin | Homo sapiens (human) | Ki | 0.5172 | 18 | 20 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 30.8000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 17.1000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 29.3000 | 3 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | Ki | 2.4000 | 1 | 1 |
| Rho-associated protein kinase 2 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 2 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 10.5000 | 2 | 2 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Ki | 60.0000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 1.3750 | 1 | 2 |
| Sentrin-specific protease 1 | Homo sapiens (human) | IC50 | 4.9450 | 2 | 2 |
| Serine protease hepsin | Homo sapiens (human) | Ki | 0.8350 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 0.4260 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.1790 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 0.5620 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 0.2990 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 4.7000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 101.6645 | 1 | 2 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 689.4155 | 1 | 2 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 428.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 2B1 | Rattus norvegicus (Norway rat) | IC50 | 0.0358 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 2.4000 | 1 | 1 |
| Suppressor of tumorigenicity 14 protein | Homo sapiens (human) | Ki | 3.3500 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 0.0600 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 2.9660 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | Ki | 0.1000 | 1 | 1 |
| Tissue-type plasminogen activator | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Tissue-type plasminogen activator | Homo sapiens (human) | Ki | 15.9233 | 3 | 3 |
| Trypanothione reductase | Trypanosoma cruzi | IC50 | 28.0000 | 2 | 2 |
| Trypsin-1 | Homo sapiens (human) | IC50 | 0.0119 | 1 | 2 |
| Trypsin-1 | Homo sapiens (human) | Ki | 0.7189 | 6 | 6 |
| Trypsin-2 | Homo sapiens (human) | IC50 | 0.0119 | 1 | 2 |
| Trypsin-2 | Homo sapiens (human) | Ki | 1.0762 | 4 | 4 |
| Trypsin-3 | Homo sapiens (human) | IC50 | 0.0119 | 1 | 2 |
| Trypsin-3 | Homo sapiens (human) | Ki | 1.0762 | 4 | 4 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 55.0000 | 1 | 1 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | Ki | 20.0000 | 1 | 1 |
| Urease | Canavalia ensiformis (jack bean) | IC50 | 15.0728 | 2 | 2 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | Ki | 6.3000 | 1 | 1 |
| Urotensin-2 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 2 |
| Vitamin K-dependent protein C | Homo sapiens (human) | IC50 | 5.6500 | 2 | 2 |
| Vitamin K-dependent protein C | Homo sapiens (human) | Ki | 20.9300 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 91.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 91.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 91.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 91.2000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 2.5100 | 1 | 1 |