Any fungal metabolite produced by metabolism of a xenobiotic compound in fungi.
ChEBI ID: 76968
Member | Definition | Class |
---|---|---|
1-hydroxy-2-naphthoic acid | A naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms. | 1-hydroxy-2-naphthoic acid |
1-naphthoic acid | A naphthoic acid carrying a carboxy group at position 1. | 1-naphthoic acid |
2-amino-4,6-dinitrotoluene | An amino-nitrotoluene that is 4,6-dinitrotoluene substituted at position 2 by an amino group. | 2-amino-4,6-dinitrotoluene |
4-amino-2,6-dinitrotoluene | An amino-nitrotoluene that is 2,6-dinitrotoluene substituted at position 4 by an amino group. | 4-amino-2,6-dinitrotoluene |
4-ethylphenol | A member of the class of phenols carrying an ethyl substituent at position 4. | 4-ethylphenol |
4',7-dihydroxyflavanone | A dihydroxyflavanone in which the two hydroxy substituents are located at positions 4' and 7. | 4',7-dihydroxyflavanone |
6-hydroxyflavanone | A monohydroxyflavanone that is flavanone substituted by a hydroxy group at position 6. | 6-hydroxyflavanone |
9-fluorenone | The simplest member of the class fluoren-9-ones that is 9H-fluorene bearing an oxo substituent at position 9. | fluoren-9-one |
melilotic acid | A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 3 is substituted by a 2-hydroxyphenyl group. | 3-(2-hydroxyphenyl)propanoic acid |
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
---|---|---|
pre-1990 | 35 (9.23) | 18.7374 |
1990's | 31 (8.18) | 18.2507 |
2000's | 128 (33.77) | 29.6817 |
2010's | 161 (42.48) | 24.3611 |
2020's | 24 (6.33) | 2.80 |
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
---|---|---|
Trials | 2 (0.47%) | 5.53% |
Reviews | 7 (1.65%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 414 (97.87%) | 84.16% |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
67.9K protein | Vaccinia virus | Potency | 0.5012 | 1 | 1 |
activating transcription factor 6 | Homo sapiens (human) | Potency | 55.6071 | 1 | 1 |
AR protein | Homo sapiens (human) | Potency | 55.9264 | 2 | 2 |
Luciferase | Photinus pyralis (common eastern firefly) | Potency | 72.9531 | 1 | 1 |
nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 28.0296 | 2 | 2 |
retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 55.8217 | 3 | 3 |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
Androgen receptor | Homo sapiens (human) | IC50 | 3.3000 | 1 | 1 |
Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 18.6209 | 1 | 1 |
Heat shock protein HSP 90-alpha | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
L-lactate dehydrogenase A chain | Homo sapiens (human) | IC50 | 500.0000 | 2 | 2 |
L-lactate dehydrogenase A chain | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
L-lactate dehydrogenase B chain | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 100.0000 | 1 | 1 |
Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 1,000.0000 | 1 | 1 |
Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 850.0000 | 1 | 1 |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
Chain A, Trichosurin | Trichosurus vulpecula (common brushtail) | Kd | 30.0000 | 1 | 1 |
glycogen synthase kinase-3 beta isoform 1 | Homo sapiens (human) | EC50 | 300.0000 | 1 | 1 |
L-lactate dehydrogenase A chain | Homo sapiens (human) | Kd | 640.0000 | 2 | 2 |
L-lactate dehydrogenase A chain | Rattus norvegicus (Norway rat) | Kd | 640.0000 | 1 | 1 |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
Sulfotransferase 1A1 | Rattus norvegicus (Norway rat) | Km | 10.0000 | 1 | 1 |