Page last updated: 2024-08-23

heme and Sepsis

heme has been researched along with Sepsis in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (6.45)	18.2507
2000's	4 (12.90)	29.6817
2010's	16 (51.61)	24.3611
2020's	9 (29.03)	2.80

Authors

Authors	Studies
Ghazal, P; Hamilton, FW; Mitchell, RE; Somers, J; Timpson, NJ	1
Aluru, NR; Bashir, R; Frederick, A; Ganguli, A; Kumar, J; Lim, J; McGuffin, R; Mostafa, A; Rayabharam, A; Saavedra, C; Valera, E; Wester, M; White, KC	1
Bai, F; Cai, Z; Chen, P; Cheng, Z; Ha, UH; Jin, Y; Wu, W; Yang, F; Yang, L; Yue, Z; Zhou, Y	1
Nishibori, M; Ousaka, D	1
Chao, YC; Chen, HY; Cheng, CF; Chung, HW; Lu, KC; Su, WL; Tsai, KW; Tzeng, IS; Wu, YK	1
Leite, GGF; Salomão, R; Scicluna, BP; van der Poll, T	1
Bauer, M; Clemens, MG; Englert, FA; Galler, K; Gouveia, Z; Heinemann, SH; Neugebauer, U; Pohnert, G; Seidel, RA; Soares, MP; Sponholz, C; Weis, S	1
Kerchberger, VE; Ware, LB	1
Bachman, MA; Brashears, S; Gladwin, MT; Gonzalez-Ferrer, S; Hod, EA; Kagan, VE; Kim-Shapiro, DB; Lee, JS; Mallampalli, RK; Mars, WM; Olonisakin, TF; Osei-Hwedieh, DO; Peñaloza, HF; Perlegas, A; Ray, A; Ray, P; Rosengart, MR; St Croix, C; Suber, T; Tejero, J; Tyurina, YY; van der Geest, R; Van Tyne, D; Xiong, Y; Xiong, Z	1
Owlia, P; Ramezanalizadeh, F; Rasooli, I	1
Ryter, SW	1
Denton, C; German, K; Grelli, KN; Juul, SE; Lee, G; Vu, PT	1
Gao, Y; Liu, K; Mori, S; Nishibori, M; Sakaguchi, M; Teshigawara, K; Wake, H; Zhong, H	1
Fujioka, K; Kalish, F; Stevenson, DK; Wong, RJ; Zhao, H	1
Bottomley, C; Ekregbesi, P; Mooney, JP; Riley, EM; Shankar-Hari, M	1
Brzychczy-Włoch, M; Bulanda, M; Gosiewski, T; Pietrzyk, A; Sroka, A	1
Fujioka, K; Kalish, F; Lu, S; Stevenson, DK; Wong, RJ; Wong, S; Zhao, H	1
Dimitrov, JD; Djoumerska-Alexieva, I; Roumenina, LT; Stefanova, T; Vassilev, T	1
Aichinger, MC; Bennett, KL; Brown, M; Colinge, J; Decker, T; Duggan, M; Eisenbarth, SC; Esterbauer, H; Gawish, R; Gorki, AD; Hladik, A; Huber, KV; Kerjaschki, D; Knapp, S; Korosec, A; Kubicek, S; Lakovits, K; Lardeau, CH; Maier, J; Martins, R; Quattrone, F; Radic-Sarikas, B; Saluzzo, S; Sharif, O; Sixt, M; Starkl, P; Superti-Furga, G; Vaahtomeri, K	1
Bonaparte, D; Bozza, FA; Cardoso, S; Cavalcante, MM; Chora, A; Ferreira, A; Gozzelino, R; Japiassú, AM; Jeney, V; Larsen, R; Marguti, I; Sepúlveda, N; Smith, A; Soares, MP; Tokaji, L	1
Alves-Filho, JC; Barja-Fidalgo, C; Cunha, FQ; Curti, C; Czaikoski, PG; Dal-Secco, D; Freitas, A; Nascimento, DC; Pestana, CR; Sônego, F; Spiller, F; Suavinha, MM; Trevelin, SC	1
Lee, LP; Mitra, D; Waldeisen, JR; Wang, T	1
Clark, D; Cope, L; Drummond, J; Fan, H; Haimbach, R; Hua, J; Joshi, A; Li, Y; McKelvey, T; McNeely, T; Montgomery, D; Ou, Y; Pancari, G; Smith, S	1
Cottin, Y; Rochette, L; Vergely, C; Zeller, M	1
Bauer, M; Claus, RA; Engel, C; Giamarellos-Bourboulis, EJ; Heinemann, SH; Huse, K; Kern, A; Kiehntopf, M; Kramer, M; Kuhnt, E; Mylona, V; Platzer, M; Reinhart, K; Routsi, C; Sponholz, C; Tsangaris, I	1
Avadhani, NG; Deutschman, CS; Levy, RJ; Raj, NR; Vijayasarathy, C	1
Coopersmith, CM; Courtois, MR; Deutschman, CS; Gruber, PJ; Levy, RJ; Piel, DA; Robertson, CM; Weinheimer, CJ	1
Deutschman, CS; Levy, RJ; Piel, DA	1
Akagi, R; Fujiwara, T; Hirakawa, M; Suzuki, T; Takahashi, T; Yamasaki, A	1
Halpern, NA; Sedlacek, M; Uribarri, J	1
Kravtsov, AN; Tynianova, VI; Ziuzina, VP	1

Reviews

5 review(s) available for heme and Sepsis

Article	Year
HMOX1 genetic polymorphisms and outcomes in infectious disease: A systematic review. PloS one, 2022, Volume: 17, Issue:5 Topics: Communicable Diseases; Genetic Predisposition to Disease; Heme; Heme Oxygenase-1; Humans; Polymorphism, Genetic; Sepsis	2022
[A new approach to combat the sepsis including COVID-19 by accelerating detoxification of hemolysis-related DAMPs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2022, Volume: 157, Issue:6 Topics: Alarmins; COVID-19; Heme; Hemoglobins; Hemolysis; Humans; Sepsis	2022
The Role of Circulating Cell-Free Hemoglobin in Sepsis-Associated Acute Kidney Injury. Seminars in nephrology, 2020, Volume: 40, Issue:2 Topics: Acetaminophen; Acute Kidney Injury; Anemia, Sickle Cell; Animals; Coronary Artery Bypass; Disseminated Intravascular Coagulation; Eryptosis; Erythrocyte Deformability; Haptoglobins; Heme; Hemoglobins; Hemolysis; Hemopexin; Humans; Kidney Tubules; Malaria; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Sepsis; Transfusion Reaction	2020
Significance of Heme and Heme Degradation in the Pathogenesis of Acute Lung and Inflammatory Disorders. International journal of molecular sciences, 2021, May-24, Volume: 22, Issue:11 Topics: Animals; Heme; Heme Oxygenase-1; Humans; Inflammation; Pneumonia; Sepsis; Systemic Inflammatory Response Syndrome	2021
Carbon monoxide: mechanisms of action and potential clinical implications. Pharmacology & therapeutics, 2013, Volume: 137, Issue:2 Topics: Animals; Carbon Monoxide; Cardiovascular Diseases; Endothelium, Vascular; Heme; Heme Oxygenase-1; Humans; Nitric Oxide; Sepsis; Vasodilation	2013

Trials

1 trial(s) available for heme and Sepsis

Article	Year
Gene polymorphisms in the heme degradation pathway and outcome of severe human sepsis. Shock (Augusta, Ga.), 2012, Volume: 38, Issue:5 Topics: Aged; Aged, 80 and over; Cohort Studies; Female; Heme; Heme Oxygenase-1; Humans; Male; Microsatellite Repeats; Middle Aged; Oxidoreductases Acting on CH-CH Group Donors; Polymorphism, Single Nucleotide; Sepsis; Severity of Illness Index; Survival Rate	2012

Other Studies

25 other study(ies) available for heme and Sepsis

Article	Year
A culture-free biphasic approach for sensitive and rapid detection of pathogens in dried whole-blood matrix. Proceedings of the National Academy of Sciences of the United States of America, 2022, 10-04, Volume: 119, Issue:40 Topics: Anti-Bacterial Agents; Candida albicans; DNA, Bacterial; DNA, Fungal; Dried Blood Spot Testing; Escherichia coli; Heme; Humans; Limit of Detection; Methicillin; Polymerase Chain Reaction; Sensitivity and Specificity; Sepsis; Staphylococcus aureus; Stem Cells	2022
High-Level Expression of Cell-Surface Signaling System Hxu Enhances Pseudomonas aeruginosa Bloodstream Infection. Infection and immunity, 2022, 10-20, Volume: 90, Issue:10 Topics: Animals; Bacterial Proteins; Haptoglobins; Heme; Hemoglobins; Hemopexin; Iron; Mice; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Signal Transduction; Transferrins; Virulence Factors	2022
Association between heme oxygenase one and sepsis development in patients with moderate-to-critical COVID-19: a single-center, retrospective observational study. European journal of medical research, 2022, Dec-04, Volume: 27, Issue:1 Topics: Biomarkers; COVID-19; Disease Progression; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Metabolism; Prognosis; Retrospective Studies; SARS-CoV-2; Sepsis	2022
Genetic signature related to heme-hemoglobin metabolism pathway in sepsis secondary to pneumonia. NPJ systems biology and applications, 2019, Volume: 5 Topics: 5-Aminolevulinate Synthetase; Blood Proteins; Carbonic Anhydrases; Computational Biology; Databases, Genetic; Gene Expression Profiling; Gene Ontology; Heme; Hemoglobin Subunits; Hemoglobins; Humans; Molecular Chaperones; Pneumonia; Sepsis; Transcriptome	2019
Labile heme impairs hepatic microcirculation and promotes hepatic injury. Archives of biochemistry and biophysics, 2019, 09-15, Volume: 672 Topics: Aged; Aged, 80 and over; Animals; Female; Heme; Hepatic Stellate Cells; Humans; Lipopolysaccharides; Liver; Male; Microcirculation; Middle Aged; Rats, Sprague-Dawley; Rats, Wistar; Sepsis; Serum Albumin, Human; Vasoconstriction	2019
Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation. The Journal of clinical investigation, 2021, 01-04, Volume: 131, Issue:1 Topics: Animals; Erythrocytes; Gene Expression Regulation; Heme; Humans; Immune Tolerance; Mice; Mice, Knockout; Phagocytosis; Sepsis; STAT1 Transcription Factor	2021
Protective response against Future microbiology, 2021, Volume: 16, Issue:3 Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Bacterial Load; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Vaccines; Disease Models, Animal; Female; Heme; Humans; Mice; Mice, Inbred BALB C; Receptors, Cell Surface; Sepsis	2021
Zinc Protoporphyrin-to-Heme Ratio and Ferritin as Measures of Iron Sufficiency in the Neonatal Intensive Care Unit. The Journal of pediatrics, 2018, Volume: 194 Topics: Biomarkers; Erythrocyte Transfusion; Erythropoietin; Female; Ferritins; Heme; Hospitalization; Humans; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Iron; Male; Protoporphyrins; Retrospective Studies; Sepsis	2018
Effects of Histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: Implications for a role under septic conditions. Journal of pharmacological sciences, 2018, Volume: 136, Issue:3 Topics: Animals; Cells, Cultured; Disease Models, Animal; Eryptosis; Erythrocyte Aggregation; Erythrocytes; Heme; Hemolysis; Humans; Mice; Phosphatidylserines; Protein Binding; Proteins; Sepsis; Thrombosis; Zinc Compounds	2018
Heme oxygenase-1 deficiency promotes severity of sepsis in a non-surgical preterm mouse model. Pediatric research, 2018, Volume: 84, Issue:1 Topics: Anemia, Hemolytic; Animals; Animals, Newborn; Anti-Inflammatory Agents; Cecum; Crosses, Genetic; Disease Models, Animal; Female; Growth Disorders; Heme; Heme Oxygenase-1; Humans; Infant, Premature; Iron Metabolism Disorders; Membrane Proteins; Mice; Mice, Knockout; Sepsis	2018
Relationship between Anaemia, Haemolysis, Inflammation and Haem Oxygenase-1 at Admission with Sepsis: a pilot study. Scientific reports, 2018, 07-25, Volume: 8, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia; Female; Haptoglobins; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Hemolysis; Hemopexin; Humans; Inflammation; Interleukin-10; Leukocyte Count; Male; Middle Aged; Pilot Projects; Sepsis; Young Adult	2018
Evaluation of the activity of thermostable DNA polymerases in the presence of heme, as a key inhibitor in the real time PCR method in diagnostics of sepsis. Acta biochimica Polonica, 2013, Volume: 60, Issue:4 Topics: DNA-Directed DNA Polymerase; Enzyme Stability; Escherichia coli; Heme; Humans; Polymerase Chain Reaction; Sepsis	2013
Induction of Heme Oxygenase-1 Attenuates the Severity of Sepsis in a Non-Surgical Preterm Mouse Model. Shock (Augusta, Ga.), 2017, Volume: 47, Issue:2 Topics: Animals; Body Weight; Chemokine CCL5; Chemokine CXCL10; Cytokines; Disease Models, Animal; Heme; Heme Oxygenase-1; Interleukin-1beta; Mice; Sepsis	2017
Heme-Exposed Pooled Therapeutic IgG Improves Endotoxemia Survival. Inflammation, 2017, Volume: 40, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Antibody Specificity; Endotoxemia; Heme; Humans; Immunoglobulin G; Inflammation; Inflammation Mediators; Lipopolysaccharides; Mice; Sepsis; Survival Rate	2017
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nature immunology, 2016, Volume: 17, Issue:12 Topics: Animals; Anti-Bacterial Agents; cdc42 GTP-Binding Protein; Cytoskeleton; Female; Gram-Negative Bacterial Infections; Guanine Nucleotide Exchange Factors; Heme; Heme Oxygenase-1; Hemolysis; Humans; Immune Evasion; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Phagocytosis; Quinine; RAW 264.7 Cells; Sepsis	2016
A central role for free heme in the pathogenesis of severe sepsis. Science translational medicine, 2010, Sep-29, Volume: 2, Issue:51 Topics: Animals; Apoptosis; Bacterial Infections; Heme; Heme Oxygenase-1; Hemopexin; Hepatocytes; HMGB1 Protein; Humans; Immune Tolerance; Mice; Models, Biological; Oxidation-Reduction; Sepsis	2010
Divergent role of heme oxygenase inhibition in the pathogenesis of sepsis. Shock (Augusta, Ga.), 2011, Volume: 35, Issue:6 Topics: Animals; Bilirubin; Cecum; Heme; Heme Oxygenase (Decyclizing); Hemin; Inflammation; Male; Mice; Mice, Inbred BALB C; Mitochondria; Neutrophil Infiltration; Neutrophils; Protoporphyrins; Receptors, Interleukin-8B; Sepsis	2011
A real-time PCR antibiogram for drug-resistant sepsis. PloS one, 2011, Volume: 6, Issue:12 Topics: Animals; Anti-Bacterial Agents; DNA; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Heme; Humans; Kanamycin; Microbial Sensitivity Tests; Models, Genetic; Models, Statistical; Probability; Real-Time Polymerase Chain Reaction; RNA, Ribosomal, 16S; Sepsis; Sheep; Spectinomycin; Stem Cells; Time Factors	2011
Characterization of the mechanism of protection mediated by CS-D7, a monoclonal antibody to Staphylococcus aureus iron regulated surface determinant B (IsdB). Frontiers in cellular and infection microbiology, 2012, Volume: 2 Topics: Animals; Antibodies, Bacterial; Antibodies, Monoclonal; Cation Transport Proteins; Complement System Proteins; Disease Models, Animal; Heme; Mice; Mice, Inbred BALB C; Mutant Proteins; Opsonin Proteins; Phagocytosis; Protein Binding; Sepsis; Staphylococcal Infections; Staphylococcus aureus; Survival Analysis	2012
Competitive and noncompetitive inhibition of myocardial cytochrome C oxidase in sepsis. Shock (Augusta, Ga.), 2004, Volume: 21, Issue:2 Topics: Animals; Binding Sites; Binding, Competitive; Blotting, Northern; Blotting, Western; Cecum; Disease Models, Animal; Electron Transport; Electron Transport Complex IV; Heme; Immunoblotting; Kinetics; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardium; Oxidative Phosphorylation; Oxygen; Phosphorylation; RNA, Messenger; Sepsis; Time Factors	2004
Mitochondrial resuscitation with exogenous cytochrome c in the septic heart. Critical care medicine, 2007, Volume: 35, Issue:9 Topics: Animals; Cytochromes c; Electron Transport Complex IV; Heme; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Oxidative Phosphorylation; Prospective Studies; Sepsis	2007
Exogenous cytochrome C restores myocardial cytochrome oxidase activity into the late phase of sepsis. Shock (Augusta, Ga.), 2008, Volume: 29, Issue:5 Topics: Animals; Cytochromes c; Electron Transport Complex IV; Heart; Heme; Kinetics; Male; Mice; Mice, Inbred C57BL; Mitochondria; Myocardium; Oxidative Stress; Phosphorylation; Sepsis	2008
Tissue-specific gene expression of heme oxygenase-1 (HO-1) and non-specific delta-aminolevulinate synthase (ALAS-N) in a rat model of septic multiple organ dysfunction syndrome. Biochemical pharmacology, 2000, Jul-15, Volume: 60, Issue:2 Topics: 5-Aminolevulinate Synthetase; Animals; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Kidney; Lipopolysaccharides; Liver; Male; Multiple Organ Failure; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepsis; Time Factors	2000
Carboxyhemoglobin and lactate levels do not correlate in critically ill patients. American journal of therapeutics, 1999, Volume: 6, Issue:5 Topics: Animals; Biomarkers; Blood Gas Analysis; Carboxyhemoglobin; Critical Illness; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Humans; Hypoxia; Lactic Acid; Rats; Sepsis	1999
[The utilization of heme iron by Yersinia pestis in human blood and blood sera]. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1990, Issue:10 Topics: Drug Resistance, Microbial; Escherichia coli; Haptoglobins; Heme; Hemin; Hemopexin; Humans; In Vitro Techniques; Iron; Plague; Sepsis; Streptomycin; Virulence; Yersinia pestis	1990