cefuroxime has been researched along with Sepsis in 36 studies
Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "FT is more effective than cefuroxime, which is commonly used during the perioperative period of urinary stones, and exerts a high antibacterial effect on these internal bacteria, and effectively reduces the probability of infection and sepsis after urinary stone surgery." | 5.34 | Antibacterial effect of fosfomycin tromethamine on the bacteria inside urinary infection stones. ( Hu, Z; Lei, Y; Liu, C; Song, F; Zhang, J, 2020) |
| "A series of patients aged 3 months to 15 years who fulfilled strict criteria for bacterial pneumonia, other respiratory infections, sepsis-like infections, and other acute infections were prospectively randomized to receive parenteral penicillin or cefuroxime randomly for 4 or 7 days." | 5.09 | Successful shortening from seven to four days of parenteral beta-lactam treatment for common childhood infections: a prospective and randomized study. ( Kallio, MJ; Peltola, H; Vuori-Holopainen, E, 2001) |
| " influenzae type b preseptal cellulitis is reported who initially responded to treatment with intravenous cefuroxime and oral cefaclor." | 3.67 | Onset of Hemophilus influenzae type-b meningitis during cefaclor therapy for preseptal cellulitis. ( Barson, WJ; Brady, MT; Cannon, HJ; Grossman, LK, 1987) |
| "Cefuroxime was chosen as the PBP-3-active antibiotic and tobramycin represented the aminoglycosides." | 1.56 | Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model. ( Larsson, A; Lipcsey, M; Maudsdotter, L; Sjölin, J; Skorup, P, 2020) |
| "A working diagnosis of severe septicemia with acute meningoencephalitis was then made and the patient was started on IV Cephtriaxone (2 g) twice daily." | 1.46 | A case report: primary amoebic meningoencephalitis in a young Zambian adult. ( Chomba, M; Fwoloshi, S; Mucheleng'anga, LA; Mutengo, MM; Ngulube, J, 2017) |
| "All animals developed severe sepsis/septic shock." | 1.40 | Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model. ( Castegren, M; Jonsson, AB; Larsson, A; Lipcsey, M; Maudsdotter, L; Sjölin, J; Skorup, P, 2014) |
| "Sepsis was higher in neonates with fever and hypothermia (p=0." | 1.38 | Neonatal sepsis at Muhimbili National Hospital, Dar es Salaam, Tanzania; aetiology, antimicrobial sensitivity pattern and clinical outcome. ( Fredrick, F; Massawe, A; Matee, MI; Mhada, TV, 2012) |
| " The pharmacokinetic profile of cefuroxime exhibited both one and two compartmental distribution." | 1.35 | Effect of severity disease on the pharmacokinetics of cefuroxime in children with multiple organ system failure. ( Asseff, IL; Guillé, GP; Olguín, HJ; Pérez, AG; Quesada, AC; Saldaña, NG; Vieyra, AC, 2008) |
| "All the babies had septic arthritis and ten cases had osteomyelitis in addition: multiple joint involvement occurred in 50% of cases." | 1.29 | Klebsiella septicaemia, osteomyelitis and septic arthritis in neonates in Ibadan, Nigeria. ( Adeyemo, AA; Akindele, JA; Omokhodion, SI, 1993) |
| "Treatment with cefuroxime appears to be a safe and effective therapy for pediatric soft-tissue infections due to H influenzae and S pneumoniae." | 1.27 | Cefuroxime therapy for bacteremic soft-tissue infections in children. ( Barson, WJ; Brady, MT; Hribar, MM; Marcon, MJ; Miller, MA; Pacini, DL; Powell, DA, 1985) |
| "Cefuroxime was active against all the gram-positive bacteria isolated from our patients as well as most of the gram-negatives." | 1.26 | Cefuroxime in soft tissue infections and septicaemia. ( Dornbusch, K; Hugo, H; Sterner, G, 1980) |
| "pneumoniae was inhibited in concentration of less than 3." | 1.26 | [Laboratory and clinical studies on cefuroxime (author's transl)]. ( Hiromatsu, K; Kotani, Y; Nishimura, T; Tabuki, K; Takashima, T, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (38.89) | 18.7374 |
| 1990's | 6 (16.67) | 18.2507 |
| 2000's | 6 (16.67) | 29.6817 |
| 2010's | 6 (16.67) | 24.3611 |
| 2020's | 4 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Jacewicz, M | 1 |
| Günzel, K | 1 |
| Rud, E | 1 |
| Sandbæk, G | 1 |
| Magheli, A | 1 |
| Busch, J | 1 |
| Hinz, S | 1 |
| Baco, E | 1 |
| Owusu, M | 1 |
| Acheampong, G | 1 |
| Annan, A | 1 |
| Marfo, KS | 1 |
| Osei, I | 1 |
| Amuasi, J | 1 |
| Sarpong, N | 1 |
| Im, J | 1 |
| Mogeni, OD | 1 |
| Chiang, HY | 1 |
| Kuo, CH | 1 |
| Jeon, HJ | 1 |
| Panzner, U | 1 |
| Park, SE | 1 |
| Marks, F | 1 |
| Owusu-Dabo, E | 1 |
| Adu-Sarkodie, Y | 1 |
| Song, F | 1 |
| Liu, C | 1 |
| Zhang, J | 1 |
| Lei, Y | 1 |
| Hu, Z | 1 |
| Skorup, P | 3 |
| Maudsdotter, L | 3 |
| Lipcsey, M | 3 |
| Larsson, A | 3 |
| Sjölin, J | 3 |
| de Vries Schultink, AHM | 1 |
| Sallevelt, BTGM | 1 |
| Meinders, AJ | 1 |
| van de Garde, EMW | 1 |
| Roescher, N | 1 |
| Chomba, M | 1 |
| Mucheleng'anga, LA | 1 |
| Fwoloshi, S | 1 |
| Ngulube, J | 1 |
| Mutengo, MM | 1 |
| Bauer, M | 1 |
| Krüger, R | 1 |
| Kölsch, U | 1 |
| Unterwalder, N | 1 |
| Meisel, C | 1 |
| Wahn, V | 1 |
| von Bernuth, H | 1 |
| Tano, E | 1 |
| Castegren, M | 2 |
| Jonsson, AB | 1 |
| Mhada, TV | 1 |
| Fredrick, F | 1 |
| Matee, MI | 1 |
| Massawe, A | 1 |
| Holak, H | 1 |
| Becker, R | 1 |
| Holak, S | 1 |
| Bauhofer, A | 1 |
| Celik, I | 1 |
| Plaul, U | 1 |
| Wulf, H | 1 |
| Torossian, A | 1 |
| Olguín, HJ | 1 |
| Asseff, IL | 1 |
| Vieyra, AC | 1 |
| Pérez, AG | 1 |
| Saldaña, NG | 1 |
| Quesada, AC | 1 |
| Guillé, GP | 1 |
| Geroulanos, S | 1 |
| Donfried, B | 1 |
| Turina, M | 1 |
| Mitchell-Jones, PJ | 1 |
| Sankey, RJ | 1 |
| Seufert, RM | 1 |
| Germann, G | 1 |
| Böttcher, W | 1 |
| Jafusco, F | 1 |
| Ansanelli, V | 1 |
| Di Lena, C | 1 |
| Marget, W | 1 |
| Belohradsky, BH | 1 |
| Roos, R | 1 |
| Hugo, H | 1 |
| Dornbusch, K | 2 |
| Sterner, G | 1 |
| Adeyemo, AA | 1 |
| Akindele, JA | 1 |
| Omokhodion, SI | 1 |
| Galloway, A | 1 |
| Glesson, HK | 1 |
| Thomas, LR | 1 |
| Baden, L | 1 |
| Zaleznik, DF | 1 |
| Peltola, H | 1 |
| Vuori-Holopainen, E | 1 |
| Kallio, MJ | 1 |
| Pérez-Trallero, E | 1 |
| Alkorta, M | 1 |
| Giménez, MJ | 1 |
| Vicente, D | 1 |
| Aguilar, L | 1 |
| Maw, A | 1 |
| Eu, KW | 1 |
| Seow-Choen, F | 1 |
| Nishimura, T | 1 |
| Hiromatsu, K | 1 |
| Takashima, T | 1 |
| Tabuki, K | 1 |
| Kotani, Y | 1 |
| Dofferhoff, AS | 1 |
| Bom, VJ | 1 |
| van Ingen, J | 1 |
| de Vries-Hospers, HG | 1 |
| Hazenberg, BP | 1 |
| van der Meer, J | 1 |
| Mulder, PO | 1 |
| Weits, J | 1 |
| Wu, SW | 1 |
| Göransson, E | 1 |
| Ransjö, U | 1 |
| Kronvall, G | 1 |
| Gothefors, L | 1 |
| Choo, PW | 1 |
| Gantz, NM | 1 |
| Huovinen, S | 1 |
| Huovinen, P | 1 |
| Torniainen, K | 1 |
| Jacoby, GA | 1 |
| Rödjer, S | 1 |
| Alestig, K | 1 |
| Bergmark, J | 1 |
| Bergström, T | 1 |
| Hultberg, B | 1 |
| Jagenburg, R | 1 |
| Olaisson, L | 1 |
| Trollfors, B | 1 |
| Westin, J | 1 |
| Morran, C | 1 |
| Greig, J | 1 |
| Gunn, R | 1 |
| Mason, B | 1 |
| Sleigh, D | 1 |
| Haddock, G | 1 |
| McArdle, C | 1 |
| Brady, MT | 2 |
| Barson, WJ | 2 |
| Cannon, HJ | 1 |
| Grossman, LK | 1 |
| Frimodt-Møller, N | 1 |
| Thomsen, VF | 1 |
| Miller, MA | 1 |
| Marcon, MJ | 1 |
| Hribar, MM | 1 |
| Pacini, DL | 1 |
| Powell, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Randomized Trial of Antibiotic Prophylaxis Versus None Before Transperineal MRI-TRUS Fusion Guided Prostate Biopsy[NCT04146142] | 550 participants (Actual) | Interventional | 2019-11-11 | Completed | |||
| Tolerance and Efficacy of Amiklin Administration During Nosocomial Infections Complicating COVID-19 in the ICU[NCT05511129] | 1,053 participants (Actual) | Observational | 2022-05-12 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for cefuroxime and Sepsis
| Article | Year |
|---|---|
Antibiotic prophylaxis versus no antibiotic prophylaxis in transperineal prostate biopsies (NORAPP): a randomised, open-label, non-inferiority trial.
Topics: Anti-Bacterial Agents; Biopsy; Cefuroxime; Humans; Male; Prostate; Sepsis; Urinary Tract Infections | 2022 |
Antibacterial effect of fosfomycin tromethamine on the bacteria inside urinary infection stones.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteria; Cefuroxime; Colony Count, Micr | 2020 |
Plasma levels of ceftriaxone in cardiovascular surgery.
Topics: Bacterial Infections; Cardiac Surgical Procedures; Cefotaxime; Ceftriaxone; Cefuroxime; Clinical Tri | 1984 |
[Perioperative antibiotic prophylaxis in elective splenectomy. A randomized prospective study].
Topics: Adult; Cefuroxime; Cephalosporins; Humans; Male; Middle Aged; Pneumonia; Postoperative Complications | 1984 |
Successful shortening from seven to four days of parenteral beta-lactam treatment for common childhood infections: a prospective and randomized study.
Topics: Adolescent; Bacterial Infections; Cefuroxime; Child; Child, Preschool; Female; Humans; Infant; Male; | 2001 |
Treatment of septicaemia in immunocompromised patients with ceftazidime or with tobramycin and cefuroxime, with special reference to renal effects.
Topics: Adult; Aged; Ceftazidime; Cefuroxime; Female; Humans; Immunologic Deficiency Syndromes; Kidney; Kidn | 1987 |
A comparison of cefuroxime and cefotetan in the prevention of wound sepsis after gastrointestinal surgery.
Topics: Bacteria; Cefotetan; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Gastrointestinal Diseases | 1987 |
29 other studies available for cefuroxime and Sepsis
| Article | Year |
|---|---|
Ralstonia mannitolilytica sepsis: a case report.
Topics: Anti-Bacterial Agents; Cefuroxime; Child, Preschool; Female; Ghana; Gram-Negative Bacterial Infectio | 2019 |
Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model.
Topics: Animals; Cefuroxime; Disease Models, Animal; Endotoxins; Escherichia coli; Escherichia coli Infectio | 2020 |
The need for gentamicin adjunctive to cefuroxime as empirical sepsis therapy: a local protocol evaluation.
Topics: Anti-Bacterial Agents; Cefuroxime; Cephalosporins; Gentamicins; Humans; Sepsis | 2021 |
A case report: primary amoebic meningoencephalitis in a young Zambian adult.
Topics: Amphotericin B; Animals; Anti-Bacterial Agents; Cefuroxime; Central Nervous System Protozoal Infecti | 2017 |
Antibiotic Prophylaxis, Immunoglobulin Substitution and Supportive Measures Prevent Infections in MECP2 Duplication Syndrome.
Topics: Administration, Intravenous; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Humans; IgA | 2018 |
Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model.
Topics: Animals; Anti-Bacterial Agents; Cefuroxime; Disease Models, Animal; Drug Therapy, Combination; Endot | 2018 |
Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model.
Topics: Animals; Anti-Bacterial Agents; Bacteremia; Bacterial Load; Cefuroxime; Critical Care; Disease Model | 2014 |
Neonatal sepsis at Muhimbili National Hospital, Dar es Salaam, Tanzania; aetiology, antimicrobial sensitivity pattern and clinical outcome.
Topics: Amikacin; Ampicillin; Anti-Infective Agents; Ceftriaxone; Cefuroxime; Cloxacillin; Escherichia coli; | 2012 |
[Long-term follow-up of bilateral endogenous Klebsiella endophthalmitis].
Topics: Abscess; Aged; Cefotaxime; Cefuroxime; Drug Therapy, Combination; Endophthalmitis; Follow-Up Studies | 2003 |
Effects of G-CSF and antibiotic prophylaxis in a 2 x 2 factorial design on outcome in septic rats.
Topics: Abdomen; Animals; Antibiotic Prophylaxis; Cefuroxime; Clinical Trials as Topic; Disease Models, Anim | 2004 |
Effect of severity disease on the pharmacokinetics of cefuroxime in children with multiple organ system failure.
Topics: Adolescent; Alanine Transaminase; Algorithms; Area Under Curve; Aspartate Aminotransferases; Cefurox | 2008 |
A case of recurrent salmonella septicaemia in an infant.
Topics: Cefuroxime; Cephalosporins; Chloramphenicol; Drug Combinations; Female; Humans; IgA Deficiency; Infa | 1984 |
[Experience with the therapeutic use of cefuroxime in neonatology].
Topics: Bacterial Infections; Cefuroxime; Cephalosporins; Gastroenteritis; Humans; Infant, Newborn; Infant, | 1981 |
Guidelines for adequate chemotherapeutic dosage in newborns and infants with septicaemia and meningitis.
Topics: Amikacin; Anti-Bacterial Agents; Cefuroxime; Colistin; Dose-Response Relationship, Drug; Humans; Inf | 1980 |
Cefuroxime in soft tissue infections and septicaemia.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefuroxime; Cephalosporins; Drug Tolerance; Female; H | 1980 |
Klebsiella septicaemia, osteomyelitis and septic arthritis in neonates in Ibadan, Nigeria.
Topics: Arthritis, Infectious; Ceftazidime; Cefuroxime; Cloxacillin; Cross Infection; Cross-Sectional Studie | 1993 |
Survival following group A streptococcal septicaemia in a centenarian.
Topics: Administration, Oral; Aged; Aged, 80 and over; Amoxicillin; Cefuroxime; Cephalosporins; Female; Huma | 1999 |
Clinical problem-solving. Chest pain with a surprising course.
Topics: Aged; Anuria; Cefuroxime; Cephalosporins; Chest Pain; Cholecystitis; Clostridium Infections; Clostri | 1999 |
Prediction of in-vivo efficacy by in-vitro early bactericidal activity with oral beta-lactams, in a dose-ranging immunocompetent mouse sepsis model, using strains of Streptococcus pneumoniae with decreasing susceptibilities to penicillin.
Topics: Amoxicillin; Animals; Area Under Curve; Cefpodoxime; Ceftizoxime; Cefuroxime; Cephalosporins; Diseas | 2001 |
Retroperitoneal sepsis complicating stapled hemorrhoidectomy: report of a case and review of the literature.
Topics: Adult; Anti-Infective Agents; Cefuroxime; Cephalosporins; Hemorrhoids; Humans; Male; Metronidazole; | 2002 |
[Laboratory and clinical studies on cefuroxime (author's transl)].
Topics: Adolescent; Bacterial Infections; Cefuroxime; Cephalosporins; Child; Child, Preschool; Common Bile D | 1979 |
Patterns of cytokines, plasma endotoxin, and acute phase proteins during the treatment of severe sepsis in humans.
Topics: Acute-Phase Proteins; Cefuroxime; Cilastatin; Drug Therapy, Combination; Endotoxins; Female; Humans; | 1991 |
Characterization of Klebsiella oxytoca septicaemia isolates resistant to aztreonam and cefuroxime.
Topics: Aztreonam; beta-Lactamases; Cefuroxime; DNA, Bacterial; Drug Resistance, Microbial; Humans; Klebsiel | 1991 |
[Cefuroxime has a good effect in severe infections in children].
Topics: Aminoglycosides; Anti-Bacterial Agents; Cefuroxime; Child, Preschool; Humans; Infant; Infant, Newbor | 1990 |
Branhamella catarrhalis pneumonia with bacteremia.
Topics: Aged; Ceftriaxone; Cefuroxime; Cross Infection; Female; Humans; Moraxella catarrhalis; Pneumonia; Se | 1989 |
Evaluation of plasmid-encoded beta-lactamase resistance in Escherichia coli blood culture isolates.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cefuroxime; Drug Resistance, Microbial; Enteroba | 1988 |
Onset of Hemophilus influenzae type-b meningitis during cefaclor therapy for preseptal cellulitis.
Topics: Cefaclor; Ceftriaxone; Cefuroxime; Cellulitis; Cephalexin; Drug Resistance, Microbial; Haemophilus I | 1987 |
The pneumococcus and the mouse protection test: inoculum, dosage and timing.
Topics: Animals; Anti-Bacterial Agents; Cefotaxime; Cefuroxime; Dose-Response Relationship, Drug; Female; In | 1986 |
Cefuroxime therapy for bacteremic soft-tissue infections in children.
Topics: beta-Lactamases; Cefuroxime; Cellulitis; Cephalosporins; Child, Preschool; Drug Resistance, Microbia | 1985 |