ketoconazole has been researched along with Sepsis in 9 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a comparative study of infection prophylaxis, patients with acute leukemia receiving remission induction therapy were assigned either no prophylaxis, sulfamethoxazole and trimethoprim, ketoconazole, or the combination of sulfamethoxazole and trimethoprim and ketoconazole." | 9.05 | Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two. ( Bodey, GP; Estey, E; Fainstein, V; Freireich, EJ; Keating, M; Maksymiuk, A; McCredie, KB; Smith, T, 1984) |
| "Candida sepsis has become an increasing problem in ICU patients with up to 50 per cent mortality rate." | 5.28 | The use of ketoconazole in prophylaxis of Candida sepsis. ( Lloyd, L; Rietschel, P; VanEgmond, E, 1989) |
| "In a comparative study of infection prophylaxis, patients with acute leukemia receiving remission induction therapy were assigned either no prophylaxis, sulfamethoxazole and trimethoprim, ketoconazole, or the combination of sulfamethoxazole and trimethoprim and ketoconazole." | 5.05 | Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two. ( Bodey, GP; Estey, E; Fainstein, V; Freireich, EJ; Keating, M; Maksymiuk, A; McCredie, KB; Smith, T, 1984) |
| " capitatum are usually sensitive to the azole compounds the explanation may be a too low daily dosage for the treatment of severely immunocompromised hosts." | 1.28 | [Trichosporon capitatum septicemia in immunosuppressed patients]. ( Bergerat, JP; Dufour, P; Herbrecht, R; Koenig, H; Liu, KL; Maloisel, F; Oberling, F; Waller, J, 1990) |
| "Candida sepsis has become an increasing problem in ICU patients with up to 50 per cent mortality rate." | 1.28 | The use of ketoconazole in prophylaxis of Candida sepsis. ( Lloyd, L; Rietschel, P; VanEgmond, E, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Estey, E | 1 |
| Maksymiuk, A | 1 |
| Smith, T | 1 |
| Fainstein, V | 1 |
| Keating, M | 1 |
| McCredie, KB | 1 |
| Freireich, EJ | 1 |
| Bodey, GP | 1 |
| Rempen, A | 1 |
| Morgan, MA | 1 |
| Cockerill, FR | 1 |
| Cortese, DA | 1 |
| Roberts, GD | 1 |
| Lee, K | 1 |
| Herbrecht, R | 1 |
| Liu, KL | 1 |
| Koenig, H | 1 |
| Waller, J | 1 |
| Dufour, P | 1 |
| Maloisel, F | 1 |
| Bergerat, JP | 1 |
| Oberling, F | 1 |
| Baker, JH | 1 |
| Goodpasture, HC | 1 |
| Kuhns, HR | 1 |
| Rinaldi, MG | 1 |
| Rietschel, P | 1 |
| VanEgmond, E | 1 |
| Lloyd, L | 1 |
| Minozzi, C | 1 |
| Decazes, JM | 1 |
| Vittecoq, D | 1 |
| Badillet, G | 1 |
| De Roquancourt, A | 1 |
| Modai, J | 1 |
| Etienne, M | 1 |
| Nemery, A | 1 |
| Darcis, JM | 1 |
| Pierard, GE | 1 |
| Demonty, J | 1 |
1 trial available for ketoconazole and Sepsis
| Article | Year |
|---|---|
Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two.
Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Drug Combinations; Drug Therapy, Combi | 1984 |
8 other studies available for ketoconazole and Sepsis
| Article | Year |
|---|---|
[Therapy of a Candida infection with ketoconazole].
Topics: Aged; Antifungal Agents; Candidiasis; Female; Humans; Imidazoles; Ketoconazole; Piperazines; Sepsis | 1983 |
Disseminated sporotrichosis with Sporothrix schenckii fungemia.
Topics: Amphotericin B; Female; Humans; Ketoconazole; Middle Aged; Sepsis; Sporothrix; Sporotrichosis | 1984 |
Use of ketoconazole in the prophylaxis of adult respiratory distress syndrome.
Topics: Humans; Ketoconazole; Respiratory Distress Syndrome; Sepsis | 1994 |
[Trichosporon capitatum septicemia in immunosuppressed patients].
Topics: Adult; Female; Fluconazole; Humans; Immune Tolerance; Ketoconazole; Leukemia, Myeloid, Acute; Male; | 1990 |
Fungemia caused by an amphotericin B-resistant isolate of Sporothrix schenckii. Successful treatment with itraconazole.
Topics: Amphotericin B; Antifungal Agents; Drug Resistance, Microbial; Humans; Itraconazole; Ketoconazole; M | 1989 |
The use of ketoconazole in prophylaxis of Candida sepsis.
Topics: Animals; Candidiasis; Disease Models, Animal; Guinea Pigs; Hydrogen-Ion Concentration; Ketoconazole; | 1989 |
[Role of invasive candidiasis in hospital pathology].
Topics: Adolescent; Adult; Aged; Amphotericin B; Blood; Candidiasis; Child; Child, Preschool; Cross Infectio | 1987 |
Disseminated candidiasis in heroin addicts. Report of two cases and review of the literature.
Topics: Adult; Candidiasis; Heroin Dependence; Humans; Ketoconazole; Male; Sepsis | 1986 |