2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Sepsis in 10 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis was induced by cecal ligation and puncture (CLP)." | 1.51 | Neuregulin-1β attenuates sepsis-induced diaphragm atrophy by activating the PI3K/Akt signaling pathway. ( Chu, T; Jiang, P; Li, ST; Liu, H; Wu, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shang, X | 1 |
| Lin, K | 1 |
| Yu, R | 1 |
| Zhu, P | 1 |
| Zhang, Y | 1 |
| Wang, L | 1 |
| Xu, J | 1 |
| Chen, K | 1 |
| Fan, TT | 1 |
| Feng, XY | 1 |
| Yang, YZ | 1 |
| Gao, F | 1 |
| Liu, Q | 1 |
| Wan, P | 1 |
| Tan, X | 1 |
| Xiang, Y | 1 |
| Tong, H | 1 |
| Yu, M | 1 |
| Wu, J | 1 |
| Liu, H | 1 |
| Chu, T | 1 |
| Jiang, P | 1 |
| Li, ST | 1 |
| Sun, N | 1 |
| Wang, H | 1 |
| Ma, L | 1 |
| Lei, P | 1 |
| Zhang, Q | 1 |
| Zhou, Z | 1 |
| Gengaro, P | 1 |
| Wang, W | 1 |
| Wang, XQ | 1 |
| Li, C | 2 |
| Faubel, S | 1 |
| Rivard, C | 1 |
| Schrier, RW | 1 |
| Jun, MS | 1 |
| Kim, HS | 1 |
| Kim, YM | 1 |
| Kim, HJ | 1 |
| Park, EJ | 1 |
| Lee, JH | 1 |
| Lee, KR | 1 |
| Kim, YS | 1 |
| Chang, KC | 1 |
| Viñuales, C | 1 |
| Gascón, S | 1 |
| Barranquero, C | 1 |
| Osada, J | 1 |
| Rodríguez-Yoldi, MJ | 1 |
| Williams, DL | 1 |
| Ha, T | 1 |
| Ozment-Skelton, T | 1 |
| Kalbfleisch, JH | 1 |
| Preiszner, J | 1 |
| Brooks, L | 1 |
| Breuel, K | 1 |
| Schweitzer, JB | 1 |
| Connelly, L | 1 |
| Madhani, M | 1 |
| Hobbs, AJ | 1 |
10 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Sepsis
| Article | Year |
|---|---|
Resveratrol Protects the Myocardium in Sepsis by Activating the Phosphatidylinositol 3-Kinases (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway and Inhibiting the Nuclear Factor-κB (NF-κB) Signaling Pathway.
Topics: Animals; Apoptosis; Cardiomyopathies; China; Chromones; Disease Models, Animal; Heart; Male; Morphol | 2019 |
Downregulation of PI3K-γ in a mouse model of sepsis-induced myocardial dysfunction.
Topics: Animals; Cardiomyopathies; Chromones; Class II Phosphatidylinositol 3-Kinases; Cytokines; Disease Mo | 2017 |
PI3K/AKT and CD40L Signaling Regulate Platelet Activation and Endothelial Cell Damage in Sepsis.
Topics: Animals; CD40 Ligand; Chromones; Endothelial Cells; Humans; Metabolic Networks and Pathways; Morphol | 2018 |
Neuregulin-1β attenuates sepsis-induced diaphragm atrophy by activating the PI3K/Akt signaling pathway.
Topics: Animals; Chromones; Diaphragm; Disease Models, Animal; Humans; Male; Morpholines; Muscle Contraction | 2019 |
Ghrelin attenuates brain injury in septic mice via PI3K/Akt signaling activation.
Topics: Animals; bcl-2-Associated X Protein; Blood-Brain Barrier; Brain Edema; Brain Injuries; Capillary Per | 2016 |
Role of NF-kappaB and PI 3-kinase/Akt in TNF-alpha-induced cytotoxicity in microvascular endothelial cells.
Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Chromones; Endothelial Cells; Endotoxemia; En | 2008 |
Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPS-activated RAW 264.7 cells and CLP-induced septic mice.
Topics: Animals; Anthracenes; Cecum; Cell Line; Cell Survival; Chromones; Cyclooxygenase 2; Disease Models, | 2012 |
Inhibitory effect of IL-1β on galactose intestinal absorption in rabbits.
Topics: Animals; Chromones; Cyclic AMP-Dependent Protein Kinases; Galactose; Genistein; In Vitro Techniques; | 2012 |
Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis.
Topics: Androstadienes; Animals; Apoptosis; beta-Glucans; Cecum; Chromones; Cytokines; Disease Susceptibilit | 2004 |
Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo.
Topics: Animals; Aorta; Blood Pressure; Blotting, Western; Bone Marrow Cells; Cells, Cultured; Chromones; Cy | 2005 |