verapamil has been researched along with Sepsis in 9 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis was induced in male Sprague-Dawley rats by implanting in their abdominal cavities fecal pellets impregnated with live Escherichia coli and Bacteroides fragilis." | 5.29 | Diltiazem and superoxide dismutase modulate hepatic acute phase response in gram-negative sepsis. ( Baumann, H; Jahreis, GP; Rose, S; Sayeed, MM, 1994) |
| "Sepsis was induced in male Sprague-Dawley rats by implanting in their abdominal cavities fecal pellets impregnated with live Escherichia coli and Bacteroides fragilis." | 1.29 | Diltiazem and superoxide dismutase modulate hepatic acute phase response in gram-negative sepsis. ( Baumann, H; Jahreis, GP; Rose, S; Sayeed, MM, 1994) |
| "Sepsis was associated with a significant increase in erythrocyte intracellular calcium concentration as compared with nonseptic controls (96." | 1.29 | Effect of sepsis on erythrocyte intracellular calcium homeostasis. ( Mollitt, DL; Todd, JC, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Rattis, BAC | 1 |
| Freitas, AC | 2 |
| Oliveira, JF | 1 |
| Calandrini-Lima, JLA | 1 |
| Figueiredo, MJ | 2 |
| Soave, DF | 1 |
| Ramos, SG | 1 |
| Celes, MRN | 1 |
| Celes, MR | 1 |
| Malvestio, LM | 1 |
| Suadicani, SO | 1 |
| Prado, CM | 1 |
| Campos, EC | 1 |
| Spray, DC | 1 |
| Tanowitz, HB | 1 |
| da Silva, JS | 1 |
| Rossi, MA | 1 |
| Rose, S | 1 |
| Baumann, H | 1 |
| Jahreis, GP | 1 |
| Sayeed, MM | 1 |
| Todd, JC | 1 |
| Mollitt, DL | 1 |
| Medvetskiĭ, EB | 1 |
| Gindich, LA | 1 |
| Cuschieri, J | 1 |
| Gourlay, D | 1 |
| Garcia, I | 1 |
| Jelacic, S | 1 |
| Maier, RV | 1 |
| Benson, DW | 1 |
| Hasselgren, PO | 1 |
| Hiyama, DT | 1 |
| James, JH | 1 |
| Li, S | 1 |
| Rigel, DF | 1 |
| Fischer, JE | 1 |
| Bosson, S | 1 |
| Kuenzig, M | 1 |
| Schwartz, SI | 1 |
| McDonough, KH | 1 |
| Lang, CH | 1 |
| Spitzer, JJ | 1 |
9 other studies available for verapamil and Sepsis
| Article | Year |
|---|---|
Effect of Verapamil, an L-Type Calcium Channel Inhibitor, on Caveolin-3 Expression in Septic Mouse Hearts.
Topics: Animals; Calcium Channels, L-Type; Caveolin 3; Heart; Humans; Male; Mice; Sepsis; Survival Analysis; | 2021 |
Disruption of calcium homeostasis in cardiomyocytes underlies cardiac structural and functional changes in severe sepsis.
Topics: Actins; Animals; Animals, Newborn; Blotting, Western; Calcium; Calpain; Cecum; Cells, Cultured; Dant | 2013 |
Diltiazem and superoxide dismutase modulate hepatic acute phase response in gram-negative sepsis.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Animals; Bacteroides fragilis; Bacteroides Infections; B | 1994 |
Effect of sepsis on erythrocyte intracellular calcium homeostasis.
Topics: Adenosine; Adenosine Triphosphate; Adolescent; Adult; Aged; Calcium; Dantrolene; Endotoxins; Erythro | 1995 |
[The functional activity of primed neutrophilic granulocytes in patients with suppurative-septic complications].
Topics: Calcium Channel Blockers; Humans; Lipopolysaccharides; Luminescent Measurements; Neutrophil Activati | 1995 |
Slow channel calcium inhibition blocks proinflammatory gene signaling and reduces macrophage responsiveness.
Topics: Analysis of Variance; Animals; Blotting, Western; Calcium Channel Blockers; Diltiazem; Dose-Response | 2002 |
Effect of sepsis on calcium uptake and content in skeletal muscle and regulation in vitro by calcium of total and myofibrillar protein breakdown in control and septic muscle: results from a preliminary study.
Topics: Animals; Calcium; Calcium Radioisotopes; Male; Methylhistidines; Muscle Proteins; Muscles; Muscular | 1989 |
Increased survival with calcium antagonists in antibiotic-treated bacteremia.
Topics: Animals; Cefoxitin; Drug Therapy, Combination; Escherichia coli Infections; Gentamicins; Mice; Nifed | 1986 |
Effect of cardiotropic agents on the myocardial dysfunction of hyperdynamic sepsis.
Topics: Animals; Blood Pressure; Calcium; Cardiac Output; Cardiovascular Agents; Heart; In Vitro Techniques; | 1985 |