nitrates has been researched along with Sepsis in 102 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Excerpt | Relevance | Reference |
---|---|---|
" Memantine, an N-methyl-D-aspartic acid receptor (NMDAR) antagonist, is able to alleviate acute lung injury (ALI)." | 8.12 | Memantine nitrate MN-08 suppresses NLRP3 inflammasome activation to protect against sepsis-induced acute lung injury in mice. ( Hu, H; Jiang, H; Sun, Y; Wang, Y; Yi, P; Zhang, G; Zhang, K; Zhang, Z, 2022) |
"Curcumin has been reported to have anti-inflammatory, antioxidant and hypoglycaemic properties, besides reducing mortality in sepsis." | 7.85 | Curcumin suppresses inflammatory cytokines and heat shock protein 70 release and improves metabolic parameters during experimental sepsis. ( Catalão, CH; de Freitas, LA; Felippotti, TT; Oliveira-Pelegrin, GR; Petenusci, S; Rocha, MJ; Silva, LS, 2017) |
"Sepsis is an arginine-deficient state and is associated with overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS)." | 7.74 | The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model. ( Akaishi, S; Endo, T; Hojo, N; Kobayashi, M; Kudo, D; Nomura, R; Sasaki, J; Shinozawa, Y; Takuma, K; Xie, XQ; Yamanouchi, S, 2008) |
"To investigate the effects of glutamine (GLN)-enriched diets before and GLN-containing total parenteral nutrition (TPN) after sepsis or both on the secretion of cytokines and their mRNA expression levels in splenocytes of rats with septic peritonitis." | 7.73 | Effects of glutamine supplementation on splenocyte cytokine mRNA expression in rats with septic peritonitis. ( Chen, WJ; Chiu, WC; Lai, YN; Lin, MT; Shang, HF; Yeh, SL, 2005) |
"To determine the changes in plasma nitrite/nitrate (NOx) and endothelin-1 (ET-1) concentrations during neonatal sepsis." | 7.72 | Plasma nitrite/nitrate and endothelin-1 concentrations in neonatal sepsis. ( Carbonell-Estrany, X; Figueras-Aloy, J; Gómez, L; Jiménez, W; Jordán, Y; Rodríguez-Miguélez, JM; Salvia, MD, 2003) |
" Here we investigated whether in vivo N-acetylcysteine treatment inhibits cellular injury in macrophages collected from rats subjected to zymosan-induced shock." | 7.70 | Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S, 1999) |
"Sepsis was induced by cecal ligation-puncture (CLP) surgery." | 5.72 | Corticosterone and Adrenocorticotrophic Hormone Secretion Is Recovered after Immune Challenge or Acute Restraint Stress in Sepsis Survivor Animals. ( Alves Rocha, MJ; Catalão, CHR; da Costa, LHA; Dos Santos-Junior, NN, 2022) |
"Sepsis is caused by a dysregulated host response to infection, often associated with acute central nervous system (CNS) dysfunction, which results in long-term cognitive impairment." | 5.48 | Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis. ( Barichello, T; da Rosa, N; Danielski, LG; de Oliveira Junior, AN; de Souza Goldim, MP; Florentino, D; Fortunato, JJ; Giustina, AD; Gomes, ML; Laurentino, AO; Mathias, K; Moreira, AP; Petronilho, F; Schuck, PF; Steckert, AV; Trombetta, T; Zarbato, GF, 2018) |
"Inflammation is difficult to control when it spreads throughout the body and often progresses into multiple organ dysfunction, eventually leading to death." | 5.37 | Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation. ( Hagiwara, S; Hasegawa, A; Koga, H; Kudo, K; Kusaka, J; Noguchi, T, 2011) |
"Endotoxemia was associated with renal dysfunctions as indicated by decreases in renal blood flow, urinary potassium excretion, and renal nitrate clearance." | 5.33 | N-Allylsecoboldine as a novel agent prevents acute renal failure during endotoxemia. ( Chiao, CW; Lee, SS; Su, MJ; Wu, CC, 2006) |
"Sepsis was produced by the CLP procedure." | 5.33 | N-acetylcysteine protects the rats against phrenic nerve dysfunction in sepsis. ( Atis, S; Bagdatoglu, O; Comelekoglu, U; Gunes, S; Nayci, A; Ozge, A, 2006) |
"Development of severe sepsis is thought to result from the overproduction of cytokines, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and nitric oxide." | 5.31 | Cerivastatin improves survival of mice with lipopolysaccharide-induced sepsis. ( Ando, H; Kobayashi, K; Nagai, Y; Ota, T; Takamura, T, 2000) |
" To evaluate the effects of NO radical on the liver in patients with postoperative sepsis, we analysed both the stable end-product of nitric oxide radical (NOx) as well as the arterial KBR (AKBR), which reflects liver tissue NAD+/NADH." | 5.09 | Nitric oxide production and hepatic dysfunction in patients with postoperative sepsis. ( Inoue, T; Kamiyama, Y; Kitade, H; Kwon, AH; Satoi, S; Takahashi, H; Takahashi, K; Wei, T, 2000) |
" Memantine, an N-methyl-D-aspartic acid receptor (NMDAR) antagonist, is able to alleviate acute lung injury (ALI)." | 4.12 | Memantine nitrate MN-08 suppresses NLRP3 inflammasome activation to protect against sepsis-induced acute lung injury in mice. ( Hu, H; Jiang, H; Sun, Y; Wang, Y; Yi, P; Zhang, G; Zhang, K; Zhang, Z, 2022) |
"Curcumin has been reported to have anti-inflammatory, antioxidant and hypoglycaemic properties, besides reducing mortality in sepsis." | 3.85 | Curcumin suppresses inflammatory cytokines and heat shock protein 70 release and improves metabolic parameters during experimental sepsis. ( Catalão, CH; de Freitas, LA; Felippotti, TT; Oliveira-Pelegrin, GR; Petenusci, S; Rocha, MJ; Silva, LS, 2017) |
"Sepsis is an arginine-deficient state and is associated with overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS)." | 3.74 | The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model. ( Akaishi, S; Endo, T; Hojo, N; Kobayashi, M; Kudo, D; Nomura, R; Sasaki, J; Shinozawa, Y; Takuma, K; Xie, XQ; Yamanouchi, S, 2008) |
"To investigate the effects of glutamine (GLN)-enriched diets before and GLN-containing total parenteral nutrition (TPN) after sepsis or both on the secretion of cytokines and their mRNA expression levels in splenocytes of rats with septic peritonitis." | 3.73 | Effects of glutamine supplementation on splenocyte cytokine mRNA expression in rats with septic peritonitis. ( Chen, WJ; Chiu, WC; Lai, YN; Lin, MT; Shang, HF; Yeh, SL, 2005) |
"Children with sepsis had a twofold reduction in antipyrine clearance." | 3.72 | Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure. ( Burckart, GJ; Carcillo, JA; Doughty, L; Frye, RF; Kaplan, SS; Kofos, D; Sasser, H, 2003) |
"To determine the changes in plasma nitrite/nitrate (NOx) and endothelin-1 (ET-1) concentrations during neonatal sepsis." | 3.72 | Plasma nitrite/nitrate and endothelin-1 concentrations in neonatal sepsis. ( Carbonell-Estrany, X; Figueras-Aloy, J; Gómez, L; Jiménez, W; Jordán, Y; Rodríguez-Miguélez, JM; Salvia, MD, 2003) |
" Here we investigated whether in vivo N-acetylcysteine treatment inhibits cellular injury in macrophages collected from rats subjected to zymosan-induced shock." | 3.70 | Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S, 1999) |
"To analyze the mechanism of vasodilation and circulatory shock occurring in patients who are treated with isolated limb perfusion with melphalan and recombinant tumor necrosis factor (TNF)-alpha for locally advanced malignant tumors." | 3.69 | Role of nitric oxide in recombinant tumor necrosis factor-alpha-induced circulatory shock: a study in patients treated for cancer with isolated limb perfusion. ( Donse, IF; Girbes, AR; Hoekstra, HJ; Maring, JK; Moshage, H; Schraffordt Koops, H; van Ginkel, RJ; Zwaveling, JH, 1996) |
"Increased plasma nitrite/nitrates and increased organ failure scores occurred in the children with sepsis who had an exaggerated proinflammatory state, despite a pronounced anti-inflammatory response." | 3.69 | Inflammatory cytokine and nitric oxide responses in pediatric sepsis and organ failure. ( Carcillo, JA; Doughty, LA; Kaplan, SS, 1996) |
"Treatment with gentamicin stabilized cardiac index (BL, 5." | 2.71 | Gentamicin improves hemodynamics in ovine septic shock after smoke inhalation injury. ( Enkhbaatar, P; Heggers, JP; Herndon, DN; Jodoin, JM; Maybauer, DM; Maybauer, MO; Morita, N; Traber, DL; Traber, LD; Westphal, M, 2005) |
"Sepsis was induced by cecal ligation-puncture (CLP) surgery." | 1.72 | Corticosterone and Adrenocorticotrophic Hormone Secretion Is Recovered after Immune Challenge or Acute Restraint Stress in Sepsis Survivor Animals. ( Alves Rocha, MJ; Catalão, CHR; da Costa, LHA; Dos Santos-Junior, NN, 2022) |
"Sepsis is caused by a dysregulated host response to infection, often associated with acute central nervous system (CNS) dysfunction, which results in long-term cognitive impairment." | 1.48 | Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis. ( Barichello, T; da Rosa, N; Danielski, LG; de Oliveira Junior, AN; de Souza Goldim, MP; Florentino, D; Fortunato, JJ; Giustina, AD; Gomes, ML; Laurentino, AO; Mathias, K; Moreira, AP; Petronilho, F; Schuck, PF; Steckert, AV; Trombetta, T; Zarbato, GF, 2018) |
" Dosing of mice with ND8008 (127." | 1.43 | A novel nitro-dexamethasone inhibits agr system activity and improves therapeutic effects in MRSA sepsis models without antibiotics. ( Cai, C; Gong, L; Gu, H; Guo, L; Li, H; Shi, Y; Song, Z; Sun, H; Tong, Y; Wei, C; Yang, L; Yang, Y; Zeng, H; Zou, Q, 2016) |
"Acute kidney injury is a frequent and serious complication of sepsis." | 1.38 | Development of oxidative stress in the peritubular capillary microenvironment mediates sepsis-induced renal microcirculatory failure and acute kidney injury. ( Gokden, N; Holthoff, JH; Mayeux, PR; Pathak, E; Seely, KA; Spencer, HJ; Wang, Z, 2012) |
" Nevertheless, vasopressin (AVP) release decreased in a dose-response manner in the early phase of sepsis." | 1.37 | Leukotriene synthesis inhibitor decreases vasopressin release in the early phase of sepsis. ( Faccioli, LH; Martins, TF; Rocha, MJ; Sorgi, CA, 2011) |
"Sepsis is a major health threat that remains refractory to treatment." | 1.37 | ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury. ( Goto, K; Hagiwara, S; Iwasaka, H; Koga, H; Kusaka, J; Noguchi, T; Uchida, T; Yokoi, I, 2011) |
"Inflammation is difficult to control when it spreads throughout the body and often progresses into multiple organ dysfunction, eventually leading to death." | 1.37 | Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation. ( Hagiwara, S; Hasegawa, A; Koga, H; Kudo, K; Kusaka, J; Noguchi, T, 2011) |
"Results Patients who developed septic shock (n = 35) had higher plasma NOx, total and free cortisol, and lower CBG concentrations than the nonseptic shock group (n = 27)." | 1.36 | Characteristics of plasma NOx levels in severe sepsis: high interindividual variability and correlation with illness severity, but lack of correlation with cortisol levels. ( Chapman, MJ; Edwards, J; Ho, JT; Lam, S; Lewis, JG; Ludbrook, G; O'Connor, S; Torpy, DJ, 2010) |
"Smoke inhalation injury is often complicated with pneumonia, which frequently leads to subsequent development of sepsis." | 1.35 | Role of neuronal nitric oxide synthase in ovine sepsis model. ( Enkhbaatar, P; Hamahata, A; Herndon, D; Jaroch, S; Jonkam, C; Lange, M; Nakano, Y; Traber, D; Traber, L; Wang, J, 2009) |
"Severe sepsis is the leading cause of death for patients in intensive care units." | 1.34 | Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis. ( Antonova, G; Cannon, J; Catravas, JD; Chatterjee, A; Dimitropoulou, C; Drakopanayiotakis, F; Snead, C; Venema, RC, 2007) |
"Sepsis was produced by the CLP procedure." | 1.33 | N-acetylcysteine protects the rats against phrenic nerve dysfunction in sepsis. ( Atis, S; Bagdatoglu, O; Comelekoglu, U; Gunes, S; Nayci, A; Ozge, A, 2006) |
"Endotoxemia was associated with renal dysfunctions as indicated by decreases in renal blood flow, urinary potassium excretion, and renal nitrate clearance." | 1.33 | N-Allylsecoboldine as a novel agent prevents acute renal failure during endotoxemia. ( Chiao, CW; Lee, SS; Su, MJ; Wu, CC, 2006) |
"The mechanism of gut injury in endotoxic shock seems unrelated to hypoxia and release of nitric oxide." | 1.32 | Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia. ( De Backer, D; Dimopoulos, G; Lobo, SM; Nagy, N; Preiser, JC; Sun, Q; Terzi, RG; Tu, Z; Vercruy, V; Vincent, JL; Vray, B, 2003) |
"Sepsis was induced by cecal ligation and puncture (CLP) method." | 1.32 | Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis. ( Bhaduri, S; Maitra, SR; Ramamurthy, N; Sorsa, T; Tervahartiala, T; Valane, PD, 2003) |
"Recent findings in human septic shock suggest that glucocorticosteroids can limit and even reverse hemodynamic disturbances and dependence on catecholamines." | 1.32 | Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock. ( Bollaert, PE; Levy, B; Longrois, D; Mallié, JP; Mansart, A; Seguin, C, 2003) |
"Although sepsis is the major cause of mortality and morbidity in the critically ill, precise mechanism(s) causing multiorgan dysfunction remain unclear." | 1.32 | Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure. ( Brealey, D; Jacques, TS; Karyampudi, S; Novelli, M; Singer, M; Smolenski, RT; Stidwill, R; Taylor, V, 2004) |
"Polymicrobial sepsis is characterized by an early, hyperdynamic phase (i." | 1.31 | Upregulation of inducible nitric oxide synthase and nitric oxide occurs later than the onset of the hyperdynamic response during sepsis. ( Chaudry, IH; Ornan, DA; Shieh, P; Wang, P; Zhou, M, 2000) |
"Development of severe sepsis is thought to result from the overproduction of cytokines, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and nitric oxide." | 1.31 | Cerivastatin improves survival of mice with lipopolysaccharide-induced sepsis. ( Ando, H; Kobayashi, K; Nagai, Y; Ota, T; Takamura, T, 2000) |
"Acute lung injury is an important feature of sepsis and increased iNOS expression and NO production contribute to the pathogenesis of this syndrome." | 1.31 | Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia. ( Joseph, M; McCormack, DG; Mehta, S; Razavi, HM; Scott, JA; Wang, LF; Weicker, S, 2001) |
"Bone resorption was assessed by measurement of urinary pyridinoline and deoxypyridinoline as a ratio to urinary creatinine." | 1.31 | Increased bone resorption in the critically ill: association with sepsis and increased nitric oxide production. ( Cuthbertson, B; Harvie, J; Ralston, SH; Robins, S; Smith, LM; Webster, N, 2002) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (6.86) | 18.7374 |
1990's | 20 (19.61) | 18.2507 |
2000's | 51 (50.00) | 29.6817 |
2010's | 21 (20.59) | 24.3611 |
2020's | 3 (2.94) | 2.80 |
Authors | Studies |
---|---|
Dos Santos-Junior, NN | 1 |
da Costa, LHA | 2 |
Catalão, CHR | 2 |
Alves Rocha, MJ | 1 |
Hu, H | 1 |
Jiang, H | 1 |
Zhang, K | 1 |
Zhang, Z | 1 |
Wang, Y | 1 |
Yi, P | 1 |
Zhang, G | 1 |
Sun, Y | 1 |
Danielski, LG | 3 |
Giustina, AD | 2 |
Bonfante, S | 1 |
de Souza Goldim, MP | 2 |
Joaquim, L | 1 |
Metzker, KL | 1 |
Biehl, EB | 1 |
Vieira, T | 1 |
de Medeiros, FD | 1 |
da Rosa, N | 2 |
Generoso, J | 1 |
Simoes, L | 1 |
Farias, HR | 1 |
da Silva Lemos, I | 1 |
Giridharan, V | 1 |
Rezin, GT | 1 |
Fortunato, JJ | 3 |
Bitencourt, RM | 1 |
Streck, EL | 1 |
Dal-Pizzol, F | 2 |
Barichello, T | 3 |
Petronilho, F | 3 |
Zarbato, GF | 1 |
Mathias, K | 1 |
Florentino, D | 2 |
de Oliveira Junior, AN | 1 |
Laurentino, AO | 1 |
Trombetta, T | 1 |
Gomes, ML | 1 |
Steckert, AV | 1 |
Moreira, AP | 1 |
Schuck, PF | 1 |
Sordi, R | 1 |
Menezes-de-Lima, O | 1 |
Della-Justina, AM | 1 |
Rezende, E | 1 |
Assreuy, J | 1 |
Oliveira-Pelegrin, GR | 2 |
Basso, PJ | 1 |
Soares, AS | 1 |
Martinez, MR | 1 |
Riester, KD | 1 |
Rocha, MJ | 3 |
Vieira, A | 1 |
Michels, M | 1 |
Lauriano, AA | 1 |
Quevedo, J | 1 |
Shen, HH | 1 |
Lam, KK | 1 |
Cheng, PY | 1 |
Kung, CW | 1 |
Chen, SY | 1 |
Lin, PC | 1 |
Chung, MT | 1 |
Lee, YM | 1 |
Yang, Y | 1 |
Li, H | 2 |
Sun, H | 1 |
Gong, L | 1 |
Guo, L | 1 |
Shi, Y | 1 |
Cai, C | 1 |
Gu, H | 1 |
Song, Z | 1 |
Yang, L | 1 |
Tong, Y | 1 |
Wei, C | 1 |
Zou, Q | 1 |
Zeng, H | 1 |
Santos-Júnior, NN | 1 |
Souza, AO | 1 |
Alberici, LC | 1 |
Rocha, MJA | 1 |
Kado, T | 1 |
Kashimoto, T | 1 |
Yamazaki, K | 1 |
Ueno, S | 1 |
Silva, LS | 1 |
Catalão, CH | 1 |
Felippotti, TT | 1 |
Petenusci, S | 1 |
de Freitas, LA | 1 |
Alvarez de Sotomayor, M | 1 |
Vega, S | 1 |
Mingorance, C | 1 |
Marhuenda, E | 1 |
Herrera, MD | 1 |
Enkhbaatar, P | 4 |
Lange, M | 2 |
Nakano, Y | 2 |
Hamahata, A | 2 |
Jonkam, C | 2 |
Wang, J | 1 |
Jaroch, S | 1 |
Traber, L | 1 |
Herndon, D | 1 |
Traber, D | 1 |
Kudo, K | 1 |
Hagiwara, S | 2 |
Hasegawa, A | 1 |
Kusaka, J | 2 |
Koga, H | 2 |
Noguchi, T | 2 |
Ho, JT | 1 |
Chapman, MJ | 1 |
O'Connor, S | 1 |
Lam, S | 1 |
Edwards, J | 1 |
Ludbrook, G | 1 |
Lewis, JG | 1 |
Torpy, DJ | 1 |
Connelly, R | 1 |
Traber, DL | 6 |
Esechie, A | 1 |
von Borzyskowski, S | 1 |
Traber, LD | 5 |
Schmalstieg, FC | 2 |
Herndon, DN | 4 |
Iwasaka, H | 1 |
Uchida, T | 1 |
Goto, K | 1 |
Yokoi, I | 1 |
Soriano, FG | 1 |
Lorigados, CB | 1 |
Pacher, P | 1 |
Szabó, C | 1 |
Choumar, A | 1 |
Tarhuni, A | 1 |
Lettéron, P | 1 |
Reyl-Desmars, F | 1 |
Dauhoo, N | 1 |
Damasse, J | 1 |
Vadrot, N | 1 |
Nahon, P | 1 |
Moreau, R | 1 |
Pessayre, D | 1 |
Mansouri, A | 1 |
Martins, TF | 1 |
Sorgi, CA | 1 |
Faccioli, LH | 1 |
Osterbur, K | 1 |
Whitehead, Z | 1 |
Sharp, CR | 1 |
DeClue, AE | 1 |
Pathak, E | 2 |
MacMillan-Crow, LA | 1 |
Mayeux, PR | 2 |
Qian, Z | 1 |
Li, J | 1 |
Han, X | 1 |
Liu, M | 1 |
Wang, Z | 1 |
Holthoff, JH | 1 |
Seely, KA | 1 |
Spencer, HJ | 1 |
Gokden, N | 1 |
van de Sandt, AM | 1 |
Windler, R | 1 |
Gödecke, A | 1 |
Ohlig, J | 1 |
Zander, S | 1 |
Reinartz, M | 1 |
Graf, J | 1 |
van Faassen, EE | 1 |
Rassaf, T | 1 |
Schrader, J | 1 |
Kelm, M | 1 |
Merx, MW | 1 |
Khadour, FH | 1 |
Panas, D | 1 |
Ferdinandy, P | 1 |
Schulze, C | 1 |
Csont, T | 1 |
Lalu, MM | 1 |
Wildhirt, SM | 1 |
Schulz, R | 1 |
Murakami, K | 2 |
McGuire, R | 2 |
Cox, RA | 2 |
Jodoin, JM | 2 |
Bjertnaes, LJ | 1 |
Katahira, J | 1 |
Hawkins, HK | 2 |
Mansart, A | 1 |
Bollaert, PE | 1 |
Seguin, C | 1 |
Levy, B | 1 |
Longrois, D | 1 |
Mallié, JP | 1 |
Carcillo, JA | 5 |
Doughty, L | 3 |
Kofos, D | 1 |
Frye, RF | 1 |
Kaplan, SS | 3 |
Sasser, H | 2 |
Burckart, GJ | 1 |
Soop, A | 1 |
Sollevi, A | 1 |
Weitzberg, E | 1 |
Lundberg, JO | 1 |
Palm, J | 1 |
Albert, J | 1 |
Figueras-Aloy, J | 1 |
Gómez, L | 1 |
Rodríguez-Miguélez, JM | 1 |
Jordán, Y | 1 |
Salvia, MD | 1 |
Jiménez, W | 1 |
Carbonell-Estrany, X | 1 |
Lobo, SM | 1 |
De Backer, D | 1 |
Sun, Q | 1 |
Tu, Z | 2 |
Dimopoulos, G | 1 |
Preiser, JC | 2 |
Nagy, N | 1 |
Vray, B | 2 |
Vercruy, V | 1 |
Terzi, RG | 1 |
Vincent, JL | 2 |
Maitra, SR | 1 |
Bhaduri, S | 1 |
Valane, PD | 1 |
Tervahartiala, T | 1 |
Sorsa, T | 1 |
Ramamurthy, N | 1 |
Brealey, D | 1 |
Karyampudi, S | 1 |
Jacques, TS | 1 |
Novelli, M | 1 |
Stidwill, R | 1 |
Taylor, V | 1 |
Smolenski, RT | 1 |
Singer, M | 1 |
Eaton, S | 1 |
Fukumoto, K | 1 |
Stefanutti, G | 1 |
Spitz, L | 1 |
Zammit, VA | 1 |
Pierro, A | 1 |
Demirbilek, S | 2 |
Ersoy, MO | 1 |
Karaman, A | 1 |
Akin, M | 1 |
Bayraktar, M | 1 |
Bayraktar, N | 1 |
Tsao, CM | 1 |
Ho, ST | 1 |
Chen, A | 1 |
Wang, JJ | 1 |
Li, CY | 1 |
Tsai, SK | 1 |
Wu, CC | 2 |
Wu, F | 1 |
Wilson, JX | 1 |
Tyml, K | 2 |
Connelly, L | 1 |
Madhani, M | 1 |
Hobbs, AJ | 1 |
Hayashi, Y | 1 |
Abe, M | 1 |
Murai, A | 1 |
Shimizu, N | 1 |
Okamoto, I | 1 |
Katsuragi, T | 1 |
Tanaka, K | 1 |
Yeh, SL | 1 |
Lai, YN | 1 |
Shang, HF | 1 |
Lin, MT | 1 |
Chiu, WC | 1 |
Chen, WJ | 1 |
Dong, HP | 1 |
Chen, HW | 1 |
Hsu, C | 1 |
Chiu, HY | 1 |
Lin, LC | 1 |
Yang, RC | 1 |
Maybauer, MO | 2 |
Maybauer, DM | 2 |
Westphal, M | 2 |
Morita, N | 2 |
Heggers, JP | 1 |
Degano, B | 1 |
Génestal, M | 1 |
Serrano, E | 1 |
Rami, J | 1 |
Arnal, JF | 1 |
Carvalho, M | 1 |
Benjamim, C | 1 |
Santos, F | 1 |
Ferreira, S | 1 |
Cunha, F | 1 |
Supinski, GS | 1 |
Callahan, LA | 1 |
Atis, S | 1 |
Nayci, A | 1 |
Ozge, A | 1 |
Comelekoglu, U | 1 |
Gunes, S | 1 |
Bagdatoglu, O | 1 |
Chiao, CW | 1 |
Lee, SS | 1 |
Su, MJ | 1 |
Torres-Dueñas, D | 1 |
Benjamim, CF | 2 |
Ferreira, SH | 3 |
Cunha, FQ | 4 |
Köstler, WJ | 1 |
Rabitsch, W | 1 |
Locker, GJ | 1 |
Staudinger, T | 1 |
El-Menyawi, I | 1 |
Frass, M | 1 |
Burgmann, H | 1 |
Fraser, JF | 1 |
Huda, R | 1 |
Mizutani, A | 1 |
Sigurdardottir, T | 1 |
Andersson, P | 1 |
Davoudi, M | 1 |
Malmsten, M | 1 |
Schmidtchen, A | 1 |
Bodelsson, M | 1 |
Machado, DP | 1 |
Nunes, FB | 1 |
Simões Pires, MG | 1 |
D'Avila, LC | 1 |
Leite, CE | 1 |
Ruschel, RE | 1 |
da Cunha, AA | 1 |
Saciura, VC | 1 |
Poloni, JA | 1 |
Lunardelli, A | 1 |
de Oliveira, JR | 1 |
Alves Filho, JC | 1 |
Dias, FS | 1 |
Poli de Figueiredo, CE | 1 |
Astolfi, RS | 1 |
Khouri, DG | 1 |
Brandizzi, LI | 1 |
Avila-Campos, MJ | 1 |
Andrade, HF | 1 |
Wheeler, DS | 1 |
Lahni, PM | 1 |
Hake, PW | 1 |
Denenberg, AG | 1 |
Wong, HR | 1 |
Snead, C | 2 |
Catravas, JD | 2 |
Zingarelli, B | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
The Critical Illness Stress-induced Immune Suppression Prevention Trial[NCT00395161] | Phase 3 | 293 participants (Actual) | Interventional | 2007-04-30 | Terminated (stopped due to Terminated for futility on 11/30/09 based on the recommendation of the DSMB) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT00395161)
Timeframe: 28 days after admission to the PICU
Intervention | participants (Number) |
---|---|
Enteral Zinc, Selenium, Glutamine, and IV Metoclopramide | 15 |
Enteral Whey Protein, IV Saline | 8 |
(NCT00395161)
Timeframe: 48 hours after admission until PICU discharge
Intervention | Days (Median) |
---|---|
Enteral Zinc, Selenium, Glutamine, and IV Metoclopramide | 1 |
Enteral Whey Protein, IV Saline | 2 |
What is reported is the number of participants with counts qualifying as lymphopenia. (NCT00395161)
Timeframe: from time of PICU admission till discharge from PICU
Intervention | participants (Number) |
---|---|
Enteral Zinc, Selenium, Glutamine, and IV Metoclopramide | 5 |
Enteral Whey Protein, IV Saline | 12 |
(NCT00395161)
Timeframe: 48 hours after PICU admission till discharge from PICU
Intervention | Mean number of events per 100 study days (Mean) |
---|---|
Daily Nutriceutical Supplementation | 4.99 |
Whey Protein | 4.83 |
(NCT00395161)
Timeframe: 48 hours after admission until 5 days after discharged from the PICU
Intervention | Days (Median) |
---|---|
Daily Nutriceutical Supplementation | 12.1 |
Whey Protein | 13.2 |
4 reviews available for nitrates and Sepsis
Article | Year |
---|---|
Myocardial carnitine palmitoyltransferase I as a target for oxidative modification in inflammation and sepsis.
Topics: Animals; Carnitine O-Palmitoyltransferase; Inflammation; Myocardium; Nitrates; Oxidation-Reduction; | 2003 |
Nitric oxide production in neonatal and pediatric sepsis.
Topics: Adult; Animals; Child; Humans; Infant, Newborn; Meningococcal Infections; Nitrates; Nitric Oxide; Ni | 1999 |
Nitric oxide and intestinal inflammation.
Topics: Antioxidants; Enteritis; Free Radical Scavengers; Homeostasis; Humans; Inflammatory Bowel Diseases; | 2000 |
[Right ventricle function].
Topics: Coronary Disease; Heart Ventricles; Humans; Hypertension, Pulmonary; Myocardial Contraction; Nitrate | 1986 |
3 trials available for nitrates and Sepsis
Article | Year |
---|---|
Gentamicin improves hemodynamics in ovine septic shock after smoke inhalation injury.
Topics: Animals; Arteries; Blood Pressure; Female; Gentamicins; Hemodynamics; Lung; Nitrates; Nitric Oxide; | 2005 |
Serum levels of end products of nitric oxide synthesis correlate positively with tumor necrosis factor alpha and negatively with body temperature in patients with postoperative abdominal sepsis.
Topics: Abdomen; Body Temperature; Female; Humans; Interleukin-6; Male; Middle Aged; Nitrates; Nitric Oxide; | 1994 |
Nitric oxide production and hepatic dysfunction in patients with postoperative sepsis.
Topics: Aged; Female; Humans; Ketone Bodies; Liver Diseases; Male; Mitochondria, Liver; Multiple Organ Failu | 2000 |
95 other studies available for nitrates and Sepsis
Article | Year |
---|---|
Corticosterone and Adrenocorticotrophic Hormone Secretion Is Recovered after Immune Challenge or Acute Restraint Stress in Sepsis Survivor Animals.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Hypothalamo-Hypophyseal System; Lipopolysaccha | 2022 |
Memantine nitrate MN-08 suppresses NLRP3 inflammasome activation to protect against sepsis-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Inflammasomes; Lipopolysaccharides; Lung; Memantine; Mice; Mice, Inbred | 2022 |
NLRP3 Activation Contributes to Acute Brain Damage Leading to Memory Impairment in Sepsis-Surviving Rats.
Topics: Acute Disease; Animals; Astrocytes; Brain; Catalase; Cytokines; Electron Transport; Glial Fibrillary | 2020 |
Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis.
Topics: Animals; Catalase; Cognition Disorders; Cytokines; Dimethyl Fumarate; Disease Models, Animal; Explor | 2018 |
Pneumonia-induced sepsis in mice: temporal study of inflammatory and cardiovascular parameters.
Topics: Animals; Bacterial Load; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Humans; Kl | 2013 |
Cleaved caspase-3 expression in hypothalamic magnocellular neurons may affect vasopressin secretion during experimental polymicrobial sepsis.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cytokines; Disease Models, Animal; Enzyme-Linked I | 2013 |
Increased on oxidative brain injury in the diabetic rats following sepsis.
Topics: Animals; Brain; Catalase; Diabetes Mellitus, Experimental; Male; Nitrates; Nitrites; Peroxidase; Pro | 2014 |
Alpha-lipoic acid prevents endotoxic shock and multiple organ dysfunction syndrome induced by endotoxemia in rats.
Topics: Animals; Antioxidants; Antithrombins; Aorta; Caspase 3; Disulfides; Endotoxemia; Enzyme Activation; | 2015 |
A novel nitro-dexamethasone inhibits agr system activity and improves therapeutic effects in MRSA sepsis models without antibiotics.
Topics: Animals; Anti-Inflammatory Agents; Bacterial Proteins; Cell Survival; Cells, Cultured; Cytokines; De | 2016 |
Brain Oxidative Stress During Experimental Sepsis Is Attenuated by Simvastatin Administration.
Topics: Animals; Apoptosis; Brain; Caspase 3; Cecum; Citrate (si)-Synthase; Cytokines; Glial Fibrillary Acid | 2017 |
Importance of fumarate and nitrate reduction regulatory protein for intestinal proliferation of Vibrio vulnificus.
Topics: Anaerobiosis; Animals; Bacterial Proteins; Cell Division; Escherichia coli; Fumarates; Gene Deletion | 2017 |
Curcumin suppresses inflammatory cytokines and heat shock protein 70 release and improves metabolic parameters during experimental sepsis.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Blood Glucose; Blood Volume; Cecum; Curcumin; Cytokin | 2017 |
Effects of HMG-CoA reductase inhibition by simvastatin on vascular dysfunction induced by lipopolysaccharide in rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase | 2008 |
Role of neuronal nitric oxide synthase in ovine sepsis model.
Topics: Animals; Disease Models, Animal; Female; Hemodynamics; Interleukin-6; Lung; Lung Injury; Nitrates; N | 2009 |
Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Cell Line; Disease Models, An | 2011 |
Characteristics of plasma NOx levels in severe sepsis: high interindividual variability and correlation with illness severity, but lack of correlation with cortisol levels.
Topics: Analysis of Variance; Dobutamine; Epinephrine; Female; Humans; Hydrocortisone; Intensive Care Units; | 2010 |
Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Interleukin-8; Lung; Nitrates; Nitric Oxide Synt | 2010 |
ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury.
Topics: Acute Lung Injury; Animals; Antioxidants; Cell Line; Chemical and Drug Induced Liver Injury; Disease | 2011 |
Effects of a potent peroxynitrite decomposition catalyst in murine models of endotoxemia and sepsis.
Topics: Animals; Endotoxemia; Lipopolysaccharides; Malondialdehyde; Metalloporphyrins; Mice; Nitrates; Nitri | 2011 |
Lipopolysaccharide-induced mitochondrial DNA depletion.
Topics: Aconitate Hydratase; Adenosine Triphosphate; Alanine Transaminase; Animals; ATP Synthetase Complexes | 2011 |
Leukotriene synthesis inhibitor decreases vasopressin release in the early phase of sepsis.
Topics: Animals; Cecum; Cell Movement; Disease Models, Animal; Enzyme Inhibitors; Hematocrit; Indoles; Leuko | 2011 |
Plasma nitrate/nitrite concentrations in dogs with naturally developing sepsis and non-infectious forms of the systemic inflammatory response syndrome.
Topics: Animals; Dog Diseases; Dogs; Female; Male; Nitrates; Nitrites; Predictive Value of Tests; Prospectiv | 2011 |
Role of mitochondrial oxidants in an in vitro model of sepsis-induced renal injury.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Cecum; Cell Survival; Cells, Cultured; Epithel | 2012 |
Effects of early administration of a novel anticholinergic drug on acute respiratory distress syndrome induced by sepsis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cholinergic Antagonists; Injections, Intraperitoneal; Interle | 2011 |
Development of oxidative stress in the peritubular capillary microenvironment mediates sepsis-induced renal microcirculatory failure and acute kidney injury.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Capillaries; Capillary Permeability; Cell Hypoxia; Cel | 2012 |
Endothelial NOS (NOS3) impairs myocardial function in developing sepsis.
Topics: Animals; Arterial Pressure; Cardiac Output; Cardiomyopathies; Coronary Circulation; Disease Models, | 2013 |
Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats.
Topics: Animals; Endotoxemia; Heart Diseases; Hydrogen Peroxide; Lipopolysaccharides; Male; Myocardial Contr | 2002 |
Heparin nebulization attenuates acute lung injury in sepsis following smoke inhalation in sheep.
Topics: Animals; Blood Coagulation; Hemodynamics; Heparin; Lung; Nebulizers and Vaporizers; Nitrates; Nitrit | 2002 |
Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock.
Topics: Adrenergic alpha-Agonists; Animals; Catecholamines; Cyclic AMP; Dexamethasone; Dose-Response Relatio | 2003 |
Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure.
Topics: Adolescent; Age Factors; Analysis of Variance; Antipyrine; Case-Control Studies; Child; Child, Presc | 2003 |
Exhaled NO and plasma cGMP increase after endotoxin infusion in healthy volunteers.
Topics: Adult; Analysis of Variance; Cyclic GMP; Endotoxins; Humans; Lipopolysaccharides; Luminescent Measur | 2003 |
Plasma nitrite/nitrate and endothelin-1 concentrations in neonatal sepsis.
Topics: Birth Weight; Endothelin-1; Female; Gestational Age; Humans; Infant, Newborn; Male; Nitrates; Nitrit | 2003 |
Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia.
Topics: Animals; Blood Pressure; Carbon Dioxide; Ileum; Intestinal Mucosa; Ischemia; Lactic Acid; Lipopolysa | 2003 |
Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blotting, Western; Extracellular Matrix; | 2003 |
Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomarkers; Blood Pressure; Blood Urea Nit | 2004 |
Effects of polyenylphosphatidylcholine on cytokines, nitrite/nitrate levels, antioxidant activity and lipid peroxidation in rats with sepsis.
Topics: Animals; Antioxidants; Cytokines; Fat Emulsions, Intravenous; Female; Lipid Peroxidation; Models, An | 2004 |
Low-dose dexamethasone ameliorates circulatory failure and renal dysfunction in conscious rats with endotoxemia.
Topics: Animals; Arteries; Blood Pressure; Blotting, Western; Calcium; Dexamethasone; Endotoxemia; Escherich | 2004 |
Ascorbate protects against impaired arteriolar constriction in sepsis by inhibiting inducible nitric oxide synthase expression.
Topics: Angiotensin II; Animals; Arterioles; Ascorbic Acid; Blood Pressure; Cecum; Drug Administration Sched | 2004 |
Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo.
Topics: Animals; Aorta; Blood Pressure; Blotting, Western; Bone Marrow Cells; Cells, Cultured; Chromones; Cy | 2005 |
Comparison of effects of nitric oxide synthase (NOS) inhibitors on plasma nitrite/nitrate levels and tissue NOS activity in septic organs.
Topics: Animals; Brain; Enzyme Inhibitors; Escherichia coli; Lipopolysaccharides; Lung; Male; Nitrates; Nitr | 2005 |
Effects of glutamine supplementation on splenocyte cytokine mRNA expression in rats with septic peritonitis.
Topics: Animal Feed; Animals; Cytokines; Glutamine; Lymphocytes; Male; Nitrates; Nitrites; Peritonitis; Rats | 2005 |
Previous heat shock treatment attenuates lipopolysaccharide-induced hyporesponsiveness of platelets in rats.
Topics: Animals; Blood Platelets; Catalase; Dose-Response Relationship, Drug; Endotoxemia; Endotoxins; Hot T | 2005 |
Effect of treatment on maxillary sinus and nasal nitric oxide concentrations in patients with nosocomial maxillary sinusitis.
Topics: Adult; Aged; Cross Infection; Device Removal; Drainage; Humans; Intubation, Gastrointestinal; Maxill | 2005 |
Effect of mast cells depletion on the failure of neutrophil migration during sepsis.
Topics: Animals; Cell Movement; Colony Count, Microbial; Interleukin-1; Interleukin-10; Male; Mast Cells; Mi | 2005 |
Hemin prevents cardiac and diaphragm mitochondrial dysfunction in sepsis.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Diaphragm; Endotoxins; Enzyme Inhibitors; Free Radi | 2006 |
N-acetylcysteine protects the rats against phrenic nerve dysfunction in sepsis.
Topics: Acetylcysteine; Animals; Catalase; Electromyography; Malondialdehyde; Nitrates; Nitrites; Oxidation- | 2006 |
N-Allylsecoboldine as a novel agent prevents acute renal failure during endotoxemia.
Topics: Acute Kidney Injury; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; | 2006 |
Failure of neutrophil migration to infectious focus and cardiovascular changes on sepsis in rats: Effects of the inhibition of nitric oxide production, removal of infectious focus, and antimicrobial treatment.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Blood Pressure; Cardiovascular System; Cecum; | 2006 |
Influence of inhaled nitric oxide on plasma nitrate concentrations in patients with adult respiratory distress syndrome and sepsis: results of a pilot study.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Fe | 2006 |
Recombinant human activated protein C improves pulmonary function in ovine acute lung injury resulting from smoke inhalation and sepsis.
Topics: Airway Obstruction; Animals; Blood Pressure; Body Temperature; Disease Models, Animal; Female; Fibri | 2006 |
In silico identification and biological evaluation of antimicrobial peptides based on human cathelicidin LL-37.
Topics: Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Blood Proteins; Cathelicidins; Chemot | 2006 |
Effects of beta-lactam antibiotics and L-arginine in the treatment of experimental sepsis in rats.
Topics: Animals; Arginine; Ascitic Fluid; Aztreonam; beta-Lactams; Ceftriaxone; Drug Therapy, Combination; I | 2006 |
Antagonic effect of the inhibition of inducible nitric oxide on the mortality of mice acutely infected with Escherichia coli and Bacteroides fragilis.
Topics: Acute Disease; Animals; Bacteroides fragilis; Bacteroides Infections; Disease Models, Animal; Escher | 2007 |
The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis.
Topics: Animals; Blood Pressure; Catechin; Disease Models, Animal; Gene Expression; Lung; Male; Mice; Mice, | 2007 |
Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis.
Topics: Animals; Benzoquinones; Chemokines; Cytokines; HSP90 Heat-Shock Proteins; Inflammation; Inflammation | 2007 |
The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model.
Topics: Animals; Arginine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines; | 2008 |
Nosocomial outbreak of nitrate-negative Serratia marcescens infections.
Topics: Aged; Cross Infection; Disease Outbreaks; Enterobacteriaceae Infections; Humans; Male; Middle Aged; | 1982 |
Nitrite and nitrate determinations in plasma: a critical evaluation.
Topics: Drug Stability; Free Radicals; Hepatitis; Humans; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduct | 1995 |
Nitric oxide production is increased in patients after burn injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Body Surface Area; Burns; Case-Control Studies; Child; E | 1996 |
Inflammatory cytokine and nitric oxide responses in pediatric sepsis and organ failure.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Interleukin-10; Interl | 1996 |
Nitrite/nitrate (NOx) and sFas antigen levels in patients with multiple organ failure.
Topics: fas Receptor; Humans; Multiple Organ Failure; Nitrates; Nitrites; Sepsis | 1996 |
Role of nitric oxide in recombinant tumor necrosis factor-alpha-induced circulatory shock: a study in patients treated for cancer with isolated limb perfusion.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chemotherapy, Cancer, Regional Perfusion | 1996 |
Plasma nitric oxide in posttrauma critical illness: a function of "sepsis" and the physiologic state severity classification quantifying the probability of death.
Topics: Adult; Creatinine; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Respiratory Distress S | 1997 |
Relation between pro- and anti-inflammatory cytokines and the production of nitric oxide (NO) in severe sepsis.
Topics: Antigens, CD; Female; Humans; Inflammation; Interleukin-10; Interleukin-6; Interleukin-8; Interleuki | 1997 |
The role of nitric oxide in experimental murine sepsis due to pyrogenic exotoxin A-producing Streptococcus pyogenes.
Topics: Animals; Cells, Cultured; Exotoxins; Immunohistochemistry; Interferon-gamma; Kidney; Kupffer Cells; | 1997 |
Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite.
Topics: Adolescent; Autopsy; Child; Child, Preschool; Densitometry; Female; Humans; Infant; Infant, Newborn; | 1997 |
Oxalated pyridoxalated hemoglobin polyoxyethylene conjugate normalizes the hyperdynamic circulation in septic sheep.
Topics: Animals; Blood Circulation; Blood Pressure; Blood Substitutes; Endothelin-1; Female; Hemoglobins; Ni | 1997 |
Measurements of total plasma nitrite and nitrate in pediatric patients with the systemic inflammatory response syndrome.
Topics: Child, Preschool; Cohort Studies; Humans; Infant; Infant, Newborn; Nitrates; Nitrites; Predictive Va | 1997 |
Nitric oxide and severe sepsis.
Topics: Child; Diet; Humans; Multiple Organ Failure; Nitrates; Nitric Oxide; Sepsis | 1997 |
The compensatory anti-inflammatory cytokine interleukin 10 response in pediatric sepsis-induced multiple organ failure.
Topics: Adolescent; Blood Cells; Cells, Cultured; Child; Child, Preschool; Humans; Infant; Infant, Newborn; | 1998 |
Growth requirements and nitrogen metabolism of Malassezia furfur.
Topics: Allantoin; Amino Acids; Ammonium Chloride; Ammonium Sulfate; Cell Division; Creatine; Creatinine; Cu | 1998 |
Myocardial dysfunction in the septic rat heart: role of nitric oxide.
Topics: Animals; Coronary Circulation; Dexamethasone; Escherichia coli Infections; In Vitro Techniques; Isot | 1998 |
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Respon | 1999 |
Detection of an approximately 100 kD protein with strong immunoreactivity to antibodies specific for inducible nitric oxide synthase (iNOS) but without NOS activity in neutrophils of patients suffering from sepsis: results of a preliminary study.
Topics: Animals; Blotting, Western; Fluorescent Antibody Technique, Indirect; Humans; Immunohistochemistry; | 1999 |
Upregulation of inducible nitric oxide synthase and nitric oxide occurs later than the onset of the hyperdynamic response during sepsis.
Topics: Animals; Cecum; Gene Expression Regulation, Enzymologic; Hemodynamics; Intestine, Small; Kidney; Liv | 2000 |
Nitric oxide produced via neuronal NOS may impair vasodilatation in septic rat skeletal muscle.
Topics: Acetylcholine; Animals; Arterioles; Enzyme Inhibitors; Lactic Acid; Male; Muscle, Skeletal; Necrosis | 2000 |
Effect of hemodialysis on plasma nitric oxide levels.
Topics: Colorimetry; Cyclic GMP; Female; Follow-Up Studies; Humans; Inflammation Mediators; Kidney Failure, | 2000 |
Role of nitric oxide in the failure of neutrophil migration in sepsis.
Topics: Animals; Ascitic Fluid; Bacteremia; Cell Movement; Colony Count, Microbial; Cytokines; Disease Model | 2000 |
Cerivastatin improves survival of mice with lipopolysaccharide-induced sepsis.
Topics: Animals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1; Lipopolysaccharides; Mice; N | 2000 |
Nitric oxide synthase and tissue injury.
Topics: Alprostadil; Animals; Arginine; Burns; Enzyme Inhibitors; Humans; Ischemia; Luminescent Measurements | 2000 |
Muscular contractile failure in septic patients: role of the inducible nitric oxide synthase pathway.
Topics: Adult; Aged; Base Sequence; Biopsy; Female; Humans; Immunohistochemistry; Male; Middle Aged; Molecul | 2000 |
Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Chimera; Endotoxemia; In Vitro Techniques; | 2001 |
Erythrocyte deformability is a nitric oxide-mediated factor in decreased capillary density during sepsis.
Topics: Acute Disease; Animals; Blood Flow Velocity; Blood Pressure; Disease Models, Animal; Electron Spin R | 2001 |
Presence of nitrotyrosine with minimal inducible nitric oxide synthase induction in lipopolysaccharide-treated pigs.
Topics: Animals; Blood Gas Analysis; Blotting, Western; Disease Models, Animal; Hemodynamics; Lipopolysaccha | 2001 |
The tissue factor and plasminogen activator inhibitor type-1 response in pediatric sepsis-induced multiple organ failure.
Topics: Adolescent; Child; Child, Preschool; Cytokines; Endothelium, Vascular; Female; Fibrinolysis; Humans; | 2002 |
Protein tyrosine nitration in the ventilatory muscles: role of nitric oxide synthases.
Topics: Animals; Extremities; Male; Mice; Mice, Knockout; Muscle Fibers, Skeletal; Muscle, Skeletal; Nitrate | 2002 |
Increased bone resorption in the critically ill: association with sepsis and increased nitric oxide production.
Topics: Adult; Aged; Amino Acids; Bone Resorption; Creatinine; Critical Illness; Female; Humans; Intensive C | 2002 |
Failure of neutrophil chemotactic function in septic patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemotaxis, Leukocyte; Female; Humans; Leukotriene B4; M | 2002 |
Inducible nitric oxide synthase (NOS2) expressed in septic patients is nitrated on selected tyrosine residues: implications for enzymic activity.
Topics: Amino Acid Sequence; Animals; Cell Line; Humans; Mice; Models, Molecular; Molecular Sequence Data; M | 2002 |
Role of nitric oxide during sepsis.
Topics: Humans; Nitrates; Nitric Acid; Nitric Oxide; Sepsis | 1992 |
Isolation of Corynebacterium group D2 from clinical specimens.
Topics: Bacteriuria; Carbohydrate Metabolism; Corynebacterium; Corynebacterium Infections; Drug Resistance, | 1987 |
[Successful treatment of candida sepsis with miconazole (author's transl)].
Topics: Adolescent; Anti-Bacterial Agents; Antifungal Agents; Benzyl Compounds; Candidiasis; Catheterization | 1974 |
[Succesful treatment of Candida albicans septicaemia after renal transplantation].
Topics: Antifungal Agents; Benzene Derivatives; Benzyl Compounds; Candidiasis; Ethers; Humans; Imidazoles; K | 1973 |
Pseudomonas stutzeri in pathological material.
Topics: Adult; Aged; Culture Media; Female; Flagella; Humans; Leg Ulcer; Lymphadenitis; Male; Nitrates; Oxyg | 1968 |
The clinical significance of Citrobacter intermedium.
Topics: Anti-Bacterial Agents; Cellulitis; Chemical Phenomena; Chemistry; Citrates; Disaccharides; Drug Resi | 1969 |