hydroxychloroquine has been researched along with Sepsis in 3 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Excerpt | Relevance | Reference |
---|---|---|
"Sepsis is an overwhelming systemic inflammatory response for which no satisfactory therapeutic drug is available." | 1.51 | Inhibition of autophagy protects against sepsis by concurrently attenuating the cytokine storm and vascular leakage. ( Chao, CH; Lu, LH; Yeh, TM, 2019) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 2 (66.67) | 2.80 |
Authors | Studies |
---|---|
Büyükcavlak, M | 1 |
Duman, I | 1 |
Eryavuz, OD | 1 |
Ünlü, A | 1 |
Duman, A | 1 |
Yehya, N | 1 |
Lu, LH | 1 |
Chao, CH | 1 |
Yeh, TM | 1 |
3 other studies available for hydroxychloroquine and Sepsis
Article | Year |
---|---|
Effects of artemisinin and hydroxychloroquine on cytokines in experimental sepsis.
Topics: Animals; Artemisinins; Cytokines; Hydroxychloroquine; Interleukin-1; Interleukin-6; Lipopolysacchari | 2022 |
Assessment of the Temporal Trajectory of Clinical Trials for COVID-19 Interventions After Highly Publicized Lay and Medical Attention.
Topics: Adrenal Cortex Hormones; Ascorbic Acid; Clinical Trials as Topic; Communication; COVID-19 Drug Treat | 2021 |
Inhibition of autophagy protects against sepsis by concurrently attenuating the cytokine storm and vascular leakage.
Topics: Animals; Autophagy; Capillary Permeability; Cytokine Release Syndrome; Cytokines; Endothelium, Vascu | 2019 |