Page last updated: 2024-10-28

hydralazine and Sepsis

hydralazine has been researched along with Sepsis in 9 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Research Excerpts

ExcerptRelevanceReference
"Sepsis is an amplified systemic immune-inflammatory response produced by a microorganism, which involves activation of inflammatory cytokine signaling pathways and oxidative stress."5.62The Therapeutic Value of Hydralazine in Reducing Inflammatory Response, Oxidative Stress, and Mortality in Animal Sepsis: Involvement of the PI3K/AKT Pathway. ( Assreuy, J; Da Silva, EAP; Heimfarth, L; Júnior, LJQ; Marinho, YYM; Menezes, IAC; Oliveira, JYS; Pereira, EWM; Santana, IR; Santos, DMD; Santos, MRVD, 2021)
"Sepsis is an amplified systemic immune-inflammatory response produced by a microorganism, which involves activation of inflammatory cytokine signaling pathways and oxidative stress."1.62The Therapeutic Value of Hydralazine in Reducing Inflammatory Response, Oxidative Stress, and Mortality in Animal Sepsis: Involvement of the PI3K/AKT Pathway. ( Assreuy, J; Da Silva, EAP; Heimfarth, L; Júnior, LJQ; Marinho, YYM; Menezes, IAC; Oliveira, JYS; Pereira, EWM; Santana, IR; Santos, DMD; Santos, MRVD, 2021)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Huang, HC1
Hsiao, TS1
Liao, MH1
Tsao, CM1
Shih, CC1
Wu, CC1
Santos, DMD1
Da Silva, EAP1
Oliveira, JYS1
Marinho, YYM1
Santana, IR1
Heimfarth, L1
Pereira, EWM1
Júnior, LJQ1
Assreuy, J1
Menezes, IAC1
Santos, MRVD1
FIASCHI, E1
GRASSI, B1
ANDRES, G1
RIVA, HL1
PICKHARDT, WL1
HOLZWORTH, RH1
SHERMAN, RL1
JOHNSON, GT1
THOMPSON, RB1
GRODY, MH1
BECK, L1
MACLAVERTY, MP1
PAVLIC, RS1
SMITH, CJ1
Diethelm, AG1
Hartley, MW1
Aldrete, JS1
Sterling, WA1
Morgan, JM1

Other Studies

9 other studies available for hydralazine and Sepsis

ArticleYear
Low-dose hydralazine improves endotoxin-induced coagulopathy and multiple organ dysfunction via its anti-inflammatory and anti-oxidative/nitrosative properties.
    European journal of pharmacology, 2020, Sep-05, Volume: 882

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Thoracic; Blood Coagulation Disorders; Blood

2020
The Therapeutic Value of Hydralazine in Reducing Inflammatory Response, Oxidative Stress, and Mortality in Animal Sepsis: Involvement of the PI3K/AKT Pathway.
    Shock (Augusta, Ga.), 2021, 11-01, Volume: 56, Issue:5

    Topics: Animals; Hydralazine; Inflammation; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene

2021
[Hydrazinophthalazine in the treatment of glomerulonephritis caused by focal sepsis].
    Schweizerische medizinische Wochenschrift, 1955, Oct-22, Volume: 85, Issue:43

    Topics: Glomerulonephritis; Hydralazine; Pharyngeal Diseases; Pharynx; Sepsis; Sympatholytics

1955
Further experience with apresoline in toxemia and hypertension of pregnancy.
    American journal of obstetrics and gynecology, 1956, Volume: 72, Issue:1

    Topics: Female; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Sepsis; Sympat

1956
A clinical trial of intravenous apresoline in the management of toxaemia of late pregnancy.
    The Journal of obstetrics and gynaecology of the British Empire, 1958, Volume: 65, Issue:3

    Topics: Bacterial Infections; Disease Management; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy; Sep

1958
Antihypertensive drugs in toxemia: a practical integrated plan of management.
    Obstetrics and gynecology, 1959, Volume: 13, Issue:2

    Topics: Antihypertensive Agents; Bacterial Infections; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy

1959
[Can infant mortality in late pregnancy toxemia be reduced by treatment with hypotensive drugs].
    Geburtshilfe und Frauenheilkunde, 1959, Volume: 19, Issue:5

    Topics: Antihypertensive Agents; Bacterial Infections; Female; Hydralazine; Infant Mortality; Pre-Eclampsia;

1959
PROGRAM FOR TOXEMIA CONTROL: STUDY OF 551 CASES.
    American journal of obstetrics and gynecology, 1965, May-01, Volume: 92

    Topics: Anticonvulsants; Delivery, Obstetric; Drug Therapy; Eclampsia; Female; Humans; Hydralazine; Pre-Ecla

1965
Treatment of accelerated hypertension and end stage renal failure by bilateral nephrectomy and renal transplantation.
    Surgery, gynecology & obstetrics, 1975, Volume: 140, Issue:2

    Topics: Acute Kidney Injury; Adult; Biopsy; Blood Pressure; Child; Creatinine; Female; Graft Rejection; Guan

1975