Page last updated: 2024-11-07

spironolactone and Sepsis

spironolactone has been researched along with Sepsis in 5 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Research Excerpts

ExcerptRelevanceReference
" Misleading subtarget concentrations were repeatedly reported, and falsely guided drug dosing resulted in a case of digoxin intoxication."1.30Intoxication due to negative canrenone interference in digoxin drug monitoring. ( Eber, B; Emmanuilidis, K; Müller, C; Steimer, W, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
PATRINI, G1
Large, DM1
Carr, PH1
Laing, I1
Davies, M1
Steimer, W1
Müller, C1
Eber, B1
Emmanuilidis, K1
Black, JA1
Challacombe, DN1
Ockenden, BG1
Sawyer, RB1
Spencer, JR1
Dudzinski, PJ1
Enis, JE1

Other Studies

5 other studies available for spironolactone and Sepsis

ArticleYear
[APROPOS OF BACTEREMIC SHOCK IN OBSTETRICS].
    Quaderni di clinica ostetrica e ginecologica, 1963, Volume: 18

    Topics: Abortion, Induced; Anti-Bacterial Agents; Central Nervous System Stimulants; Communicable Diseases;

1963
Hyperkalaemia in diabetes mellitus--potential hazards of coexisting hyporeninaemic hypoaldosteronism.
    Postgraduate medical journal, 1984, Volume: 60, Issue:703

    Topics: Adult; Aldosterone; Diabetes Mellitus, Type 1; Female; Humans; Hyperkalemia; Male; Middle Aged; Reni

1984
Intoxication due to negative canrenone interference in digoxin drug monitoring.
    Lancet (London, England), 1999, Oct-02, Volume: 354, Issue:9185

    Topics: Aged; Canrenone; Digoxin; Drug Interactions; Drug Monitoring; Enzyme Multiplied Immunoassay Techniqu

1999
Nephrotic syndrome associated with bacteraemia after shunt operations for hydrocephalus.
    Lancet (London, England), 1965, Nov-06, Volume: 2, Issue:7419

    Topics: Edema; Escherichia coli; Female; Fluorescent Antibody Technique; Glomerulonephritis; Humans; Hydroce

1965
Hypernatremia with pharmacologic doses of steroids.
    American journal of surgery, 1967, Volume: 114, Issue:5

    Topics: Aged; Female; Humans; Hydrocortisone; Hypernatremia; Male; Methylprednisolone; Middle Aged; Pituitar

1967