| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Inflammatory Response Syndrome, Systemic
[description not available] | 0 | 2.31 | 1 | 0 |
Cerebral Infarction, Middle Cerebral Artery
[description not available] | 0 | 2.31 | 1 | 0 |
Systemic Inflammatory Response Syndrome
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever | 0 | 2.31 | 1 | 0 |
Infarction, Middle Cerebral Artery
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction. | 0 | 2.31 | 1 | 0 |
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 2.41 | 1 | 0 |
Chronic Illness
[description not available] | 0 | 2.31 | 1 | 0 |
Lesion of Sciatic Nerve
[description not available] | 0 | 2.31 | 1 | 0 |
Constriction, Pathological
[description not available] | 0 | 2.31 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 3.12 | 4 | 0 |
Nerve Pain
[description not available] | 0 | 2.31 | 1 | 0 |
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 2.31 | 1 | 0 |
Constriction, Pathologic
The condition of an anatomical structure's being constricted beyond normal dimensions. | 0 | 2.31 | 1 | 0 |
Neuralgia
Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve. | 0 | 2.31 | 1 | 0 |
Carcinoma, Epidermoid
[description not available] | 0 | 2.41 | 1 | 0 |
Acantholysis Bullosa
[description not available] | 0 | 2.41 | 1 | 0 |
Innate Inflammatory Response
[description not available] | 0 | 2.69 | 2 | 0 |
Cancer of Skin
[description not available] | 0 | 2.41 | 1 | 0 |
Cockayne-Touraine Disease
[description not available] | 0 | 2.41 | 1 | 0 |
Carcinoma, Squamous Cell
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 2.41 | 1 | 0 |
Epidermolysis Bullosa
Group of genetically determined disorders characterized by the blistering of skin and mucosae. There are four major forms: acquired, simple, junctional, and dystrophic. Each of the latter three has several varieties. | 0 | 2.41 | 1 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 2.69 | 2 | 0 |
Skin Neoplasms
Tumors or cancer of the SKIN. | 0 | 2.41 | 1 | 0 |
Epidermolysis Bullosa Dystrophica
Form of epidermolysis bullosa characterized by atrophy of blistered areas, severe scarring, and nail changes. It is most often present at birth or in early infancy and occurs in both autosomal dominant and recessive forms. All forms of dystrophic epidermolysis bullosa result from mutations in COLLAGEN TYPE VII, a major component fibrils of BASEMENT MEMBRANE and EPIDERMIS. | 0 | 2.41 | 1 | 0 |
Acute Brain Injuries
[description not available] | 0 | 2.72 | 2 | 0 |
Brain Hemorrhage, Cerebral
[description not available] | 0 | 2.41 | 1 | 0 |
Brain Injuries
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits. | 0 | 2.72 | 2 | 0 |
Cerebral Hemorrhage
Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA. | 0 | 2.41 | 1 | 0 |
Blood Poisoning
[description not available] | 0 | 2.41 | 1 | 0 |
Cardiomyopathies, Primary
[description not available] | 0 | 2.41 | 1 | 0 |
Cardiomyopathies
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS). | 0 | 2.41 | 1 | 0 |
Sepsis
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | 0 | 2.41 | 1 | 0 |
Disease Exacerbation
[description not available] | 0 | 6.08 | 4 | 4 |
Friedreich Disease
[description not available] | 0 | 9.59 | 11 | 7 |
Friedreich Ataxia
An autosomal recessive disease, usually of childhood onset, characterized pathologically by degeneration of the spinocerebellar tracts, posterior columns, and to a lesser extent the corticospinal tracts. Clinical manifestations include GAIT ATAXIA, pes cavus, speech impairment, lateral curvature of spine, rhythmic head tremor, kyphoscoliosis, congestive heart failure (secondary to a cardiomyopathy), and lower extremity weakness. Most forms of this condition are associated with a mutation in a gene on chromosome 9, at band q13, which codes for the mitochondrial protein frataxin. (From Adams et al., Principles of Neurology, 6th ed, p1081; N Engl J Med 1996 Oct 17;335(16):1169-75) The severity of Friedreich ataxia associated with expansion of GAA repeats in the first intron of the frataxin gene correlates with the number of trinucleotide repeats. (From Durr et al, N Engl J Med 1996 Oct 17;335(16):1169-75) | 1 | 11.59 | 11 | 7 |
Arthritis, Degenerative
[description not available] | 0 | 2.6 | 1 | 0 |
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. | 0 | 2.6 | 1 | 0 |
Cognitive Decline
[description not available] | 0 | 2.6 | 1 | 0 |
Acute Confusional Senile Dementia
[description not available] | 0 | 2.6 | 1 | 0 |
Alzheimer Disease
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 2.6 | 1 | 0 |
Cognitive Dysfunction
Diminished or impaired mental and/or intellectual function. | 0 | 2.6 | 1 | 0 |
Luft Disease
[description not available] | 0 | 4.55 | 1 | 1 |
Mitochondrial Myopathies
A group of muscle diseases associated with abnormal mitochondria function. | 0 | 4.55 | 1 | 1 |
Angiospasm, Intracranial
[description not available] | 0 | 2.25 | 1 | 0 |
Hemorrhage, Subarachnoid
[description not available] | 0 | 2.25 | 1 | 0 |
Subarachnoid Hemorrhage
Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status. | 0 | 7.25 | 1 | 0 |
Vasospasm, Intracranial
Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN). | 0 | 2.25 | 1 | 0 |
Electron Transport Chain Deficiencies, Mitochondrial
[description not available] | 0 | 3.06 | 1 | 0 |
Mitochondrial Diseases
Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes. | 0 | 3.06 | 1 | 0 |
Acute Kidney Failure
[description not available] | 0 | 2.15 | 1 | 0 |
Injury, Ischemia-Reperfusion
[description not available] | 0 | 2.15 | 1 | 0 |
Reperfusion Injury
Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA. | 0 | 2.15 | 1 | 0 |
Acute Kidney Injury
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | 0 | 2.15 | 1 | 0 |
Alloxan Diabetes
[description not available] | 0 | 2.17 | 1 | 0 |
Diabetes Mellitus
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE. | 0 | 2.17 | 1 | 0 |
Aura
[description not available] | 0 | 2.17 | 1 | 0 |
Epilepsy
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) | 0 | 2.17 | 1 | 0 |
Asthma, Bronchial
[description not available] | 0 | 2.21 | 1 | 0 |
Asthma
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). | 0 | 2.21 | 1 | 0 |
Dermatoses
[description not available] | 0 | 2.1 | 1 | 0 |
Skin Diseases
Diseases involving the DERMIS or EPIDERMIS. | 0 | 2.1 | 1 | 0 |
Experimental Radiation Injuries
[description not available] | 0 | 2.1 | 1 | 0 |
Dermatitis, Radiation-Induced
[description not available] | 0 | 2.1 | 1 | 0 |
Radiodermatitis
A cutaneous inflammatory reaction occurring as a result of exposure to ionizing radiation. | 0 | 2.1 | 1 | 0 |
Skin Ulcer
An ULCER of the skin and underlying tissues. | 0 | 2.1 | 1 | 0 |
Cancer of Prostate
[description not available] | 0 | 2.1 | 1 | 0 |
Prostatic Neoplasms
Tumors or cancer of the PROSTATE. | 0 | 2.1 | 1 | 0 |
Acute Radiation Syndrome
A condition caused by a brief whole body exposure to more than one sievert dose equivalent of radiation. Acute radiation syndrome is initially characterized by ANOREXIA; NAUSEA; VOMITING; but can progress to hematological, gastrointestinal, neurological, pulmonary, and other major organ dysfunction. | 0 | 7.11 | 1 | 0 |