Page last updated: 2024-10-22

amifostine anhydrous and Sepsis

amifostine anhydrous has been researched along with Sepsis in 3 studies

Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Research Excerpts

ExcerptRelevanceReference
"Sepsis is responsible for more than 5 million deaths worldwide every year."1.72The nephroprotective effect of amifostine in a cecal ligation-induced sepsis model in terms of oxidative stress and inflammation. ( Atak, M; Batcik, Ş; Mercantepe, F; Mercantepe, T; Topcu, A; Tumkaya, L; Uydu, HA, 2022)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Batcik, Ş1
Tumkaya, L1
Mercantepe, T1
Atak, M1
Topcu, A1
Uydu, HA1
Mercantepe, F1
Giles, FJ1
Shi, GG1
Cortes, JE1
Thomas, D1
Keating, AR1
Kantarjian, HM1
Keating, MJ1
O'Brien, SM1
Kelly, DJ1
Rees, JC1

Trials

1 trial available for amifostine anhydrous and Sepsis

ArticleYear
Amifostine does not reduce the toxicity of the fludarabine and cyclophosphamide regimen in patients with chronic lymphocytic leukemia.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:3

    Topics: Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Humans; Leukem

2003

Other Studies

2 other studies available for amifostine anhydrous and Sepsis

ArticleYear
The nephroprotective effect of amifostine in a cecal ligation-induced sepsis model in terms of oxidative stress and inflammation.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:24

    Topics: Acute Kidney Injury; Amifostine; Animals; Inflammation; Interleukin-6; NF-kappa B; Oxidative Stress;

2022
Effect of sublethal gamma radiation on host defenses in experimental scrub typhus.
    Infection and immunity, 1986, Volume: 52, Issue:3

    Topics: Amifostine; Animals; Antibodies, Bacterial; Gamma Rays; Immunity; Mice; Orientia tsutsugamushi; Radi

1986