Page last updated: 2024-08-17

nad and Sepsis

nad has been researched along with Sepsis in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (11.43)	18.7374
1990's	6 (17.14)	18.2507
2000's	7 (20.00)	29.6817
2010's	11 (31.43)	24.3611
2020's	7 (20.00)	2.80

Authors

Authors	Studies
Gong, S; Sauer, JD; Tong, Y; Wang, Y; Xie, R; Ye, M; Zhao, Y	1
Cui, P; He, Z; Li, A; Liu, H; Sun, X; Wang, Y; Yan, J; Yan, X; Yu, L; Zhang, J	1
Deng, XM; Li, HR; Li, P; Liu, Q; Sun, CY; Sun, XY; Wang, JF; Yu, CM; Zhu, CL	1
Chen, LW; Chen, XY; Dong, FB; Dong, W; Lu, ZQ; Xiao, Z; Yang, XY; Yao, RQ; Yao, YM; Zhang, C; Zhang, J; Zhao, GJ	1
Cao, T; Ding, W; Fan, GC; Ji, X; Ni, R; Peng, T; Zhang, Z	1
Li, F; Ling, Y; Liu, TF; McCall, CE; Tao, J; Wang, M; Xu, L; Zhang, J; Zhang, S; Zhu, X	1
Chen, Y; Cho, GJ; Choi, HS; Chung, HT; Joe, Y; Kim, HJ; Kim, UH; Park, J; Park, JW; Rah, SY; Ryter, SW; Ryu, J	1
Audrito, V; Brandimarte, L; Deaglio, S; Messana, VG	1
Carré, JE; Clatworthy, I; Duchen, MR; Dyson, A; Pinto, BB; Ritter, C; Singer, M; Umbrello, M	1
Arulkumaran, N; Courtneidge, H; Duchen, MR; Greco, E; Hall, AM; Pollen, S; Singer, M; Tam, FWK; Unwin, RJ	1
Bar-Or, D; Bar-Or, R; Brody, EN; Rael, LT	1
Hoth, JJ; Liu, T; McCall, CE; Vachharajani, VT; Wang, X; Yoza, BK	1
Arts, RJ; Bonten, MJ; Cheng, SC; Cremer, OL; Giamarellos-Bourboulis, EJ; Gresnigt, MS; Joosten, LA; Kox, M; Lachmandas, E; Leentjens, J; Manjeri, GR; Netea, MG; Pickkers, P; Schultz, MJ; Scicluna, BP; van de Veerdonk, FL; van der Meer, AJ; van der Poll, T; Wagenaars, JA; Willems, PH	1
Ai, ML; Ai, YH; Ma, XH; Peng, QY; Zhang, LN; Zou, Y	1
Decoster, B; Favory, R; Hassoun, SM; Lancel, S; Motterlini, R; Neviere, R	1
Domanska, G; Fusch, G; Gruendling, M; Haas, JP; Holtfreter, B; Reinke, P; Schefold, JC; Schuett, C; Westerholt, A; Zeden, JP	1
El Gazzar, M; Liu, TF; McCall, CE; Vachharajani, VT; Yoza, BK	1
Apostolova, N; Garcia-Bou, R; Herance, R; Hernandez-Mijares, A; Rocha, M; Victor, VM	1
Liu, TF; McCall, CE; Vachharajani, VT; Yoza, BK	1
Fink, MP	2
Asimakis, GK; Chinkes, DL; Gore, DC; Hart, DW; Rinehart, AJ	1
Ashburn, JH; Clemens, MG; Huynh, T; Keller, SA; Paxian, M	1
Martin, C; Rose, J	1
Cowley, RA; Jones, RT; Kamiyama, Y; Sato, T; Tanaka, J; Trump, BF	1
DeFranco, LM; Holmes, RL; Otto, M	1
Avontuur, JA; Bruining, HA; Ince, C	1
Avontuur, JA; Bruining, HA; Coremans, JM; Ince, C; Sinaasappel, M; van der Sluijs, JP	1
Fink, M	1
Jurasinski, C; Kimball, SR; Vary, TC	1
Caputi, AP; Costantino, G; Cuzzocrea, S	1
Inoue, T; Kamiyama, Y; Kitade, H; Kwon, AH; Satoi, S; Takahashi, H; Takahashi, K; Wei, T	1
Ackerman, JJ; Chen, RD; Hotchkiss, RS; Karl, IE; Lowry, OH; Manchester, JK; Neil, JJ; Song, SK	1
Gilbert, VE	1
Baehner, RL; Johnston, RB; Nathan, DG	1

Reviews

5 review(s) available for nad and Sepsis

Article	Year
The Extracellular NADome Modulates Immune Responses. Frontiers in immunology, 2021, Volume: 12 Topics: Adenosine Triphosphate; Animals; Humans; Immunomodulation; Inflammatory Bowel Diseases; NAD; Neoplasms; Obesity; Sepsis	2021
Oxidative stress in severe acute illness. Redox biology, 2015, Volume: 4 Topics: Acute Disease; Antioxidants; Brain Injuries; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Multiple Trauma; Myocardial Infarction; NAD; Oxidative Stress; Reactive Oxygen Species; Sepsis; Stroke; Superoxide Dismutase; Thioredoxins	2015
Sirtuins Link Inflammation and Metabolism. Journal of immunology research, 2016, Volume: 2016 Topics: Adenosine Triphosphate; Alzheimer Disease; Animals; Cardiovascular Diseases; Energy Metabolism; Gene Expression Regulation; Homeostasis; Humans; Inflammation; Metabolic Syndrome; NAD; Oxidative Stress; Reactive Oxygen Species; Sepsis; Signal Transduction; Sirtuins	2016
Bench-to-bedside review: Cytopathic hypoxia. Critical care (London, England), 2002, Volume: 6, Issue:6 Topics: Adenosine Triphosphate; Animals; Cell Respiration; Humans; Lipopolysaccharides; Mitochondrial Diseases; NAD; Oxidative Phosphorylation; Poly(ADP-ribose) Polymerases; Sepsis	2002
Cytopathic hypoxia in sepsis. Acta anaesthesiologica Scandinavica. Supplementum, 1997, Volume: 110 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anemia; Animals; Cell Hypoxia; Citric Acid Cycle; Electron Transport; Endotoxemia; Enzyme Activation; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Humans; Hypoxia; Mitochondria; NAD; Oxidation-Reduction; Oxygen; Oxygen Consumption; Phosphorylation; Poly(ADP-ribose) Polymerases; Pyruvates; Sepsis	1997

Trials

1 trial(s) available for nad and Sepsis

Article	Year
Nitric oxide production and hepatic dysfunction in patients with postoperative sepsis. Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:3 Topics: Aged; Female; Humans; Ketone Bodies; Liver Diseases; Male; Mitochondria, Liver; Multiple Organ Failure; NAD; Nitrates; Nitric Oxide; Nitrites; Postoperative Complications; Sepsis	2000

Other Studies

29 other study(ies) available for nad and Sepsis

Article	Year
NAD(H)-loaded nanoparticles for efficient sepsis therapy via modulating immune and vascular homeostasis. Nature nanotechnology, 2022, Volume: 17, Issue:8 Topics: Homeostasis; Humans; Inflammation; NAD; Nanoparticles; Sepsis	2022
Rapidly Inhibiting the Inflammatory Cytokine Storms and Restoring Cellular Homeostasis to Alleviate Sepsis by Blocking Pyroptosis and Mitochondrial Apoptosis Pathways. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:14 Topics: Apoptosis; Cytokine Release Syndrome; Homeostasis; Humans; Inflammasomes; Inflammation; Lipopolysaccharides; NAD; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Sepsis	2023
β-Nicotinamide mononucleotide activates NAD+/SIRT1 pathway and attenuates inflammatory and oxidative responses in the hippocampus regions of septic mice. Redox biology, 2023, Volume: 63 Topics: Animals; Brain Ischemia; Hippocampus; Lipopolysaccharides; Mice; NAD; Nicotinamide Mononucleotide; Oxidative Stress; Sepsis; Sirtuin 1	2023
SUPPLEMENTATION WITH NICOTINAMIDE RIBOSIDE ATTENUATES T CELL EXHAUSTION AND IMPROVES SURVIVAL IN SEPSIS. Shock (Augusta, Ga.), 2023, 08-01, Volume: 60, Issue:2 Topics: Animals; Dietary Supplements; Mice; NAD; Sepsis; Sirtuin 1; T-Cell Exhaustion	2023
Nicotinamide mononucleotide as a therapeutic agent to alleviate multi-organ failure in sepsis. Journal of translational medicine, 2023, Dec-06, Volume: 21, Issue:1 Topics: Animals; Endothelial Cells; Inflammation; Mice; Mitochondrial Diseases; NAD; Nicotinamide Mononucleotide; Sepsis; Sirtuin 3	2023
Switch of NAD Salvage to Frontiers in immunology, 2019, Volume: 10 Topics: Animals; Cytokines; Endotoxins; Enzyme Inhibitors; Female; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Male; Mice; NAD; Nicotinamide Phosphoribosyltransferase; Sepsis; Sirtuin 1; THP-1 Cells; Transcription Factor RelB; Tumor Necrosis Factor-alpha	2019
Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis. Cell reports, 2020, 01-28, Volume: 30, Issue:4 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Animals; Autophagosomes; Calcium; Carbon Monoxide; Cell Line; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Macrophages; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD; NADP; Ras Homolog Enriched in Brain Protein; RNA, Small Interfering; Sepsis; Sirtuin 1; TOR Serine-Threonine Kinases; Tristetraprolin	2020
Improved Survival in a Long-Term Rat Model of Sepsis Is Associated With Reduced Mitochondrial Calcium Uptake Despite Increased Energetic Demand. Critical care medicine, 2017, Volume: 45, Issue:8 Topics: Animals; Calcium; Dobutamine; Echocardiography; Male; Microscopy, Electron; Mitochondria; Myocytes, Cardiac; NAD; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sepsis	2017
Renal Tubular Cell Mitochondrial Dysfunction Occurs Despite Preserved Renal Oxygen Delivery in Experimental Septic Acute Kidney Injury. Critical care medicine, 2018, Volume: 46, Issue:4 Topics: Acute Kidney Injury; Animals; Cell Survival; Disease Models, Animal; Kidney Function Tests; Kidney Tubules; Male; Membrane Potential, Mitochondrial; Mitochondria; NAD; Oxygen; Oxygen Consumption; Prospective Studies; Rats; Rats, Wistar; Reactive Oxygen Species; Renal Circulation; Sepsis	2018
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. Nature immunology, 2016, Volume: 17, Issue:4 Topics: Adenosine Triphosphate; Adult; Animals; Antifungal Agents; Aspergillosis; Candidiasis, Invasive; Cytokines; Endotoxemia; Energy Metabolism; Escherichia coli Infections; Female; Glycolysis; Humans; Immune Tolerance; Immunity, Innate; Immunoblotting; Interferon-gamma; Lactic Acid; Leukocytes; Lipopolysaccharides; Macrophages; Male; Mice; Middle Aged; Monocytes; NAD; Oxidative Phosphorylation; Oxygen Consumption; Prospective Studies; Sepsis; Transcriptome; Young Adult	2016
Blocking NAD(+)/CD38/cADPR/Ca(2+) pathway in sepsis prevents organ damage. The Journal of surgical research, 2016, Volume: 201, Issue:2 Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Malondialdehyde; Membrane Glycoproteins; Multiple Organ Failure; NAD; Random Allocation; Rats, Sprague-Dawley; Sepsis; Superoxide Dismutase	2016
Carbon monoxide rescues mice from lethal sepsis by supporting mitochondrial energetic metabolism and activating mitochondrial biogenesis. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:2 Topics: Animals; Carbon Monoxide; Disease Models, Animal; DNA, Mitochondrial; Energy Metabolism; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred ICR; Mitochondria, Heart; NAD; Organometallic Compounds; Oxidative Stress; Oxygen Consumption; Peritonitis; Sepsis	2009
Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients. Anaesthesia and intensive care, 2010, Volume: 38, Issue:2 Topics: Adult; Critical Illness; Female; Humans; Kynurenine; Male; Middle Aged; NAD; Renal Insufficiency; Sepsis; Tryptophan	2010
NAD+-dependent SIRT1 deacetylase participates in epigenetic reprogramming during endotoxin tolerance. The Journal of biological chemistry, 2011, Mar-18, Volume: 286, Issue:11 Topics: Cell Line; Drug Resistance; Endotoxins; Epigenesis, Genetic; Histones; Humans; Interleukin-1beta; NAD; Promoter Regions, Genetic; Protein Biosynthesis; Protein Stability; Sepsis; Sirtuin 1; Toll-Like Receptor 4; Transcription Factor RelA; Transcription Factor RelB; Tumor Necrosis Factor-alpha	2011
Mitochondrial antioxidants alleviate oxidative and nitrosative stress in a cellular model of sepsis. Pharmaceutical research, 2011, Volume: 28, Issue:11 Topics: Antioxidants; Endotoxins; Enzyme Inhibitors; Escherichia coli; Glutathione; Human Umbilical Vein Endothelial Cells; Humans; Mitochondria; Models, Biological; Molecular Targeted Therapy; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrosation; Oxidative Stress; Oxygen; Peroxynitrous Acid; Reactive Oxygen Species; Sepsis	2011
NAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response. The Journal of biological chemistry, 2012, Jul-27, Volume: 287, Issue:31 Topics: Adaptation, Physiological; Animals; Carrier Proteins; Cell Line; Cytokines; Energy Metabolism; Fatty Acids; Glucose; Glucose Transporter Type 1; Glycolysis; Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leukocytes; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Monocyte-Macrophage Precursor Cells; NAD; Nicotinamide Phosphoribosyltransferase; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; RNA-Binding Proteins; Sepsis; Sirtuin 1; Sirtuins; Toll-Like Receptor 4; Transcription Factors	2012
Sepsis-induced failure of hepatic energy metabolism. The Journal of surgical research, 2003, Volume: 115, Issue:1 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bacteremia; Blood Flow Velocity; Blood Pressure; Energy Metabolism; Hepatic Artery; Hepatic Veins; Infusions, Intravenous; Lactic Acid; Liver; Male; NAD; Oxygen; Oxygen Consumption; Phosphorylation; Portal Vein; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Shock, Septic; Swine	2003
Kupffer cell ablation improves hepatic microcirculation after trauma and sepsis. The Journal of trauma, 2005, Volume: 58, Issue:4 Topics: Animals; Cecum; Endothelin-1; Femoral Fractures; Ferrous Compounds; Kupffer Cells; Ligation; Liver; Liver Circulation; Male; Microcirculation; NAD; Rats; Rats, Sprague-Dawley; Sepsis	2005
Tissue bioenergetics and microvascular perfusion are impaired in rat ileal mucosa in normotensive sepsis. Microcirculation (New York, N.Y. : 1994), 2006, Volume: 13, Issue:1 Topics: Animals; Arterioles; Bacterial Translocation; Capillaries; Capillary Permeability; Energy Metabolism; Ileum; Intestinal Mucosa; Male; Microcirculation; Microscopy, Fluorescence; Microscopy, Video; NAD; Perfusion; Rats; Rats, Sprague-Dawley; Sepsis	2006
Bacteremic shock: aspects of high-energy metabolism of rat liver following living Escherichia coli injection. The Journal of surgical research, 1982, Volume: 33, Issue:1 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cytoplasm; Energy Metabolism; Escherichia coli Infections; Ketones; Liver; Male; Mitochondria, Liver; NAD; Rats; Sepsis; Shock, Septic	1982
Novel method of biotyping Haemophilus influenzae that uses API 20e. Journal of clinical microbiology, 1982, Volume: 15, Issue:6 Topics: Bacteriological Techniques; beta-Lactamases; Cerebrospinal Fluid; Haemophilus influenzae; Hemin; Humans; NAD; Sepsis	1982
Inhibition of nitric oxide synthesis causes myocardial ischemia in endotoxemic rats. Circulation research, 1995, Volume: 76, Issue:3 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Coronary Circulation; Dexamethasone; Endotoxins; Male; Methylene Blue; Myocardial Ischemia; NAD; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxygen Consumption; Rats; Rats, Wistar; Sepsis; Vasopressins	1995
Intestinal ischemia during hypoxia and experimental sepsis as observed by NADH videofluorimetry and quenching of Pd-porphine phosphorescence. Advances in experimental medicine and biology, 1994, Volume: 361 Topics: Animals; Disease Models, Animal; Energy Metabolism; Fluorometry; Hypoxia; Intestinal Mucosa; Intestines; Ischemia; Luminescent Measurements; Male; Mesoporphyrins; Metalloporphyrins; NAD; Oxygen; Palladium; Rats; Rats, Wistar; Sepsis; Shock, Septic	1994
Reduced 40S initiation complex formation in skeletal muscle during sepsis. Molecular and cellular biochemistry, 1998, Volume: 178, Issue:1-2 Topics: Animals; Guanine Nucleotide Exchange Factors; Male; Muscle, Skeletal; NAD; NADP; Oxidation-Reduction; Peptide Chain Initiation, Translational; Proteins; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; RNA, Transfer, Met; Sepsis	1998
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat. Shock (Augusta, Ga.), 1999, Volume: 11, Issue:2 Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Macrophages, Peritoneal; Male; NAD; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Shock; Tyrosine; Zymosan	1999
Cytopathic hypoxia in sepsis: a true problem? Minerva anestesiologica, 2001, Volume: 67, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aerobiosis; Animals; Cell Hypoxia; Enzyme Activation; Flavin-Adenine Dinucleotide; Humans; Mitochondria; NAD; Phosphorylation; Poly(ADP-ribose) Polymerases; Sepsis	2001
Sepsis does not impair tricarboxylic acid cycle in the heart. The American journal of physiology, 1991, Volume: 260, Issue:1 Pt 1 Topics: Adenosine Triphosphate; Animals; Blood Pressure; Citric Acid Cycle; Disease Models, Animal; Female; Heart; Heart Rate; Hematocrit; Magnetic Resonance Spectroscopy; Myocardium; NAD; NADP; Phosphocreatine; Phosphorus; Rats; Rats, Inbred Strains; Reference Values; Sepsis	1991
Blood pyruvate and lactate during febrile human infections. Metabolism: clinical and experimental, 1968, Volume: 17, Issue:10 Topics: Anemia, Aplastic; Cellulitis; Convalescence; Endocarditis, Subacute Bacterial; Escherichia coli Infections; Fever; Humans; Infections; Klebsiella Infections; Lactates; Meningitis; NAD; Peritonitis; Pneumonia; Pneumonia, Aspiration; Pyruvates; Sepsis; Shock, Septic; Staphylococcal Infections; Urinary Tract Infections; Veins	1968
Comparative study of the metabolic and bactericidal characteristics of severely glucose-6-phosphate dehydrogenase-deficient polymorphonuclear leukocytes and leukocytes from children with chronic granulomatous disease. Journal of the Reticuloendothelial Society, 1972, Volume: 12, Issue:2 Topics: Acid Phosphatase; Alkaline Phosphatase; Bacterial Infections; Blood Bactericidal Activity; Carbon Isotopes; Child; Escherichia coli Infections; Female; Glucosephosphate Dehydrogenase Deficiency; Glucuronidase; Granuloma; Hexosephosphates; Humans; Hydrogen Peroxide; Klebsiella Infections; Leukocyte Count; Leukocytes; Male; Middle Aged; NAD; NADP; Oxidoreductases; Peroxidases; Phagocytosis; Pyridines; Sepsis	1972