10-nitro-oleic-acid has been researched along with Sepsis* in 1 studies
1 other study(ies) available for 10-nitro-oleic-acid and Sepsis
Article | Year |
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The nitrated fatty acid, 10-nitrooleate inhibits the neutrophil chemotaxis via peroxisome proliferator-activated receptor gamma in CLP-induced sepsis in mice.
The inhibition of polymorphonuclear neutrophils' (PMNs) migration to the source of injury is among the most prominent aspects of immunosuppression following sepsis, although the precise mechanisms involved remain unclear and multifaceted. Increasing evidence connects this immunosuppression to nitric oxide (NO), as NO production is a classic feature of inflammation probably through neutrophil activation and migration. Nitrated fatty acids (NFA) such as 10-nitrooleate (OA-NO Topics: Animals; Cecum; Chemotaxis; Female; Ligation; Mice, Inbred C57BL; Neutrophils; Oleic Acids; PPAR gamma; Sepsis | 2019 |