procarbazine has been researched along with Sepsis in 4 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of 14 splenectomized patients with Hodgkin's disease who were treated with total nodal irradiation and combination chemotherapy (MOPP), fulminant sepsis developed in three (21." | 1.26 | Fulminant sepsis after the successful treatment of Hodgkin's disease. ( Aisenberg, AC; Weitzman, S, 1977) |
| " Because of rapid progression of the amyloidosis and further infections, cytotoxic drug therapy was stopped, corticosteroid dosage was decreased, and supplementary immunoglobulin therapy was instituted." | 1.25 | Amyloidosis associated with dermatomyositis and features of multiple myeloma. The progression of amyloidosis associated with corticosteroid and cytotoxic drug therapy. ( Dawkins, RL; Zilko, PJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamanaka, R | 1 |
| Morii, K | 1 |
| Shinbo, Y | 1 |
| Takeuchi, S | 1 |
| Tamura, T | 1 |
| Hondoh, H | 1 |
| Takahashi, H | 2 |
| Onda, K | 1 |
| Tanaka, R | 1 |
| Zilko, PJ | 1 |
| Dawkins, RL | 1 |
| Weitzman, S | 1 |
| Aisenberg, AC | 1 |
| Rosenberg, SA | 1 |
| Kaplan, HS | 1 |
1 trial available for procarbazine and Sepsis
| Article | Year |
|---|---|
The evolution and summary results of the Stanford randomized clinical trials of the management of Hodgkin's disease: 1962-1984.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Combine | 1985 |
3 other studies available for procarbazine and Sepsis
| Article | Year |
|---|---|
Modified ProMACE-MOPP hybrid regimen with moderate-dose methotrexate for patients with primary CNS lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Centra | 2005 |
Amyloidosis associated with dermatomyositis and features of multiple myeloma. The progression of amyloidosis associated with corticosteroid and cytotoxic drug therapy.
Topics: Agammaglobulinemia; Amyloidosis; Bence Jones Protein; Dermatomyositis; gamma-Globulins; Humans; Immu | 1975 |
Fulminant sepsis after the successful treatment of Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Agents; Female; Haemophilus Infections; Hodgkin Disease; Humans; M | 1977 |