Page last updated: 2024-08-21

quinazolines and Sepsis

quinazolines has been researched along with Sepsis in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Li, Z; Min, W; Ni, W; Pierce, RW; Yin, M; Zhang, H; Zhou, HJ1
Brown-Driver, V; Cunningham, ML; Finn, J; Hilgers, MT; Hough, G; Kwan, BP; Lam, T; Nelson, KJ; Ong, V; Shaw, KJ; Trzoss, M1
Cha, JH; Cho, NC; Kim, D; Kim, H; Kim, T; Kim, YK; Kwak, J; Lee, J; Lee, KT; No, KT; Pae, AN; Park, KD; Seo, SH; Shin, JS1
Daiber, A; Daub, S; Gori, T; Grabbe, S; Hausding, M; Karbach, S; Klein, T; Knorr, M; Kossmann, S; Kröller-Schön, S; Münzel, T; Oelze, M; Schell, R; Scholz, A; Schuff, A; Schulz, E; Sudowe, S; Wenzel, P1
Abacioglu, N; Altug, S; Demirkay, B; Tunçtan, B; Uludag, O1
Beutel, G; Cassidy, J; Chick, J; Gill, S; Glen, H; Schöffski, P; Twelves, C1
Evans, TR; Fullarton, GM; Garcia-Vargas, J; Harris, AL; Lofts, FJ; Mackay, HJ; McDonald, AC; McInnes, A; Paul, J; Raby, N; Soukop, M1

Trials

2 trial(s) available for quinazolines and Sepsis

ArticleYear
Phase I study of OSI-7904L, a novel liposomal thymidylate synthase inhibitor in patients with refractory solid tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-01, Volume: 11, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Deoxyuridine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genotype; Glutarates; Homocysteine; Humans; Infusions, Intravenous; Isoindoles; Liposomes; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Polymorphism, Genetic; Quinazolines; Sepsis; Thymidylate Synthase; Time Factors; Treatment Outcome

2005
A phase II study of epirubicin, cisplatin and raltitrexed combination chemotherapy (ECT) in patients with advanced oesophageal and gastric adenocarcinoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Drug Hypersensitivity; Enteritis; Epirubicin; Esophageal Neoplasms; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neutropenia; Pulmonary Embolism; Quinazolines; Sepsis; Stomach Neoplasms; Survival Analysis; Thiophenes; Treatment Outcome

2001

Other Studies

5 other study(ies) available for quinazolines and Sepsis

ArticleYear
BMX Represses Thrombin-PAR1-Mediated Endothelial Permeability and Vascular Leakage During Early Sepsis.
    Circulation research, 2020, 02-14, Volume: 126, Issue:4

    Topics: Animals; Capillary Permeability; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Mice, Inbred C57BL; Mice, Knockout; Permeability; Protein-Tyrosine Kinases; Pyrroles; Quinazolines; Receptor, PAR-1; Sepsis; Signal Transduction; Thrombin

2020
Structure-based design of new dihydrofolate reductase antibacterial agents: 7-(benzimidazol-1-yl)-2,4-diaminoquinazolines.
    Journal of medicinal chemistry, 2014, Feb-13, Volume: 57, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Benzimidazoles; Drug Resistance, Bacterial; Folic Acid Antagonists; Humans; Mice; Microbial Sensitivity Tests; Models, Molecular; Quinazolines; Sepsis; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

2014
Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR2) antagonists.
    Bioorganic & medicinal chemistry, 2015, Dec-15, Volume: 23, Issue:24

    Topics: Amination; Animals; Anti-Inflammatory Agents; Cell Line; Dinoprostone; Interleukin-1beta; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; NF-kappa B; Quinazolines; Receptor, PAR-2; Sepsis; Tumor Necrosis Factor-alpha

2015
Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition.
    Cardiovascular research, 2012, Oct-01, Volume: 96, Issue:1

    Topics: Administration, Oral; Animals; Antioxidants; Diabetic Angiopathies; Dipeptidyl-Peptidase IV Inhibitors; Humans; Leukocytes; Linagliptin; Lipopolysaccharides; Male; Neutrophils; Oxidative Stress; Purines; Quinazolines; Rats; Rats, Wistar; Respiratory Burst; Sepsis; Vasodilation

2012
Effects of cyclooxygenase inhibitors on nitric oxide production and survival in a mice model of sepsis.
    Pharmacological research, 2003, Volume: 48, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Female; Furans; Lipopolysaccharides; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Quinazolines; Sepsis; Sulfonamides

2003