Page last updated: 2024-10-20

spermidine and Sepsis

spermidine has been researched along with Sepsis in 4 studies

Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Research Excerpts

ExcerptRelevanceReference
"We employed mice sepsis-induced AKI model and explored the potential renoprotective effect of spermidine in vivo with different administration time and routes."8.12Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway. ( Jiang, X; Li, X; Liu, X; Shi, B; Wang, S; Zhou, X, 2022)
"We employed mice sepsis-induced AKI model and explored the potential renoprotective effect of spermidine in vivo with different administration time and routes."4.12Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway. ( Jiang, X; Li, X; Liu, X; Shi, B; Wang, S; Zhou, X, 2022)
"Sepsis was induced by cecal ligation and puncture (CLP); control rats were sham-operated."1.29Influence of sepsis and endotoxemia on polyamine metabolism in mucosa of small intestine in rats. ( Fischer, JE; Hasselgren, PO; Meyer, TA; Noguchi, Y; Ogle, CK; Tiao, G, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Li, X2
Zhou, X1
Liu, X1
Jiang, X1
Shi, B1
Wang, S1
Aung, MS1
Urushibara, N1
Kawaguchiya, M1
Hirose, M1
Ito, M1
Habadera, S1
Kobayashi, N1
Shrestha, A1
Sil, D1
Malladi, SS1
Warshakoon, HJ1
David, SA1
Noguchi, Y1
Meyer, TA1
Tiao, G1
Ogle, CK1
Fischer, JE1
Hasselgren, PO1

Other Studies

4 other studies available for spermidine and Sepsis

ArticleYear
Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway.
    Molecular medicine (Cambridge, Mass.), 2022, 09-04, Volume: 28, Issue:1

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Inflammasomes; Macrophages; Mice; Mice, Inbred

2022
Clonal diversity of methicillin-resistant Staphylococcus aureus (MRSA) from bloodstream infections in northern Japan: Identification of spermidine N-acetyltransferase gene (speG) in staphylococcal cassette chromosomes (SCCs) associated with type II and IV
    Journal of global antimicrobial resistance, 2021, Volume: 24

    Topics: Acetyltransferases; Bacterial Toxins; Chromosomes; DNA, Bacterial; Humans; Japan; Leukocidins; Methi

2021
Structure-activity relationships of lipopolysaccharide sequestration in N-alkylpolyamines.
    Bioorganic & medicinal chemistry letters, 2009, May-01, Volume: 19, Issue:9

    Topics: Cell Line; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Endotoxins; Humans; Lipop

2009
Influence of sepsis and endotoxemia on polyamine metabolism in mucosa of small intestine in rats.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Animals; Endotoxins; Intestinal Mucosa; Jejunum; Male; Ornithine D

1996