Page last updated: 2024-10-31

miconazole and Sepsis

miconazole has been researched along with Sepsis in 12 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Research Excerpts

ExcerptRelevanceReference
"73 kg premature newborn developed systemic candidiasis and were treated with intravenous miconazole."7.66Miconazole therapy for systemic candidiasis in a conjoined (Siamese) twin and a premature newborn. ( Chopra, DR; Grendahl, JG; Haws, EB; Rajani, K; Sung, JP, 1979)
"The effectiveness of miconazole was evaluated in 9 documented fungal infections, 4 of which were candidal sepsis."3.67[Therapeutic effect of miconazole on fungal infection in patients with hematological malignancies]. ( Nagai, K; Nakayama, S; Yabe, H; Yoshida, T, 1984)
"73 kg premature newborn developed systemic candidiasis and were treated with intravenous miconazole."3.66Miconazole therapy for systemic candidiasis in a conjoined (Siamese) twin and a premature newborn. ( Chopra, DR; Grendahl, JG; Haws, EB; Rajani, K; Sung, JP, 1979)
"Cutaneous candidiasis is a disease that affects children as well as adults."1.38[Generalized cutaneous candidiasis in newborn at term]. ( Cañadas-De la Fuente, GA; Cantero-Hinojosa, J; El Ahmed, HH; Fernández-Castillo, R; González-Jiménez, E; Lardón-Fernández, M, 2012)
"In five cases intrahepatic biliary stasis was diagnosed in the course of a Candida albicans septicaemia."1.25[Fungal infections after renal transplantation (author's transl)]. ( Deutsch, E; Kopsa, H; Schmidt, P; Thurner, J; Zazgornik, J, 1975)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
El Ahmed, HH1
Cañadas-De la Fuente, GA1
Fernández-Castillo, R1
González-Jiménez, E1
Cantero-Hinojosa, J1
Lardón-Fernández, M1
Yücel, N1
Lefering, R1
Maegele, M1
Max, M1
Rossaint, R1
Koch, A1
Schwarz, R1
Korenkov, M1
Beuth, J1
Bach, A1
Schierholz, J1
Pulverer, G1
Neugebauer, EA1
Nagai, K1
Yabe, H1
Yoshida, T1
Nakayama, S1
Ryan, DW1
Freeman, R1
Sung, JP1
Rajani, K1
Chopra, DR1
Grendahl, JG1
Haws, EB1
Meberg, A1
Langslet, A1
Sovde, A1
Kolstad, A1
Zazgornik, J1
Schmidt, P1
Thurner, J1
Kopsa, H1
Deutsch, E1
Sotoyama, K1
Toyama, K1
Mukae, H1
Iwamoto, M1
Kinoshita, A1
Takase, T1
Mori, N1
Ishino, T1
Kohno, S1
Yamaguchi, K1
Hirota, M1
Hara, K1
Kamei, H1
Toki, H1
Fugii, M1
Okabe, K1
Segawa, Y1
Burke, AM1
Fitzsimons, RB1
Kearney, PJ1

Trials

1 trial available for miconazole and Sepsis

ArticleYear
Reduced colonization and infection with miconazole-rifampicin modified central venous catheters: a randomized controlled clinical trial.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Catheteriza

2004

Other Studies

11 other studies available for miconazole and Sepsis

ArticleYear
[Generalized cutaneous candidiasis in newborn at term].
    Biomedica : revista del Instituto Nacional de Salud, 2012, Volume: 32, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Anti-Infective Agents; Bacteremia; Bicarbonates; Ca

2012
[Therapeutic effect of miconazole on fungal infection in patients with hematological malignancies].
    The Japanese journal of antibiotics, 1984, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Candidiasis; Drug Evaluation; Esophagitis; Female; Hodgkin Disease; Humans;

1984
Miconazole as a treatment for Candida septicaemia.
    Intensive care medicine, 1980, Volume: 6, Issue:4

    Topics: Aged; Candidiasis; Child; Female; Humans; Imidazoles; Klebsiella Infections; Male; Miconazole; Paren

1980
Miconazole therapy for systemic candidiasis in a conjoined (Siamese) twin and a premature newborn.
    American journal of surgery, 1979, Volume: 138, Issue:5

    Topics: Candida albicans; Candidiasis; Humans; Imidazoles; Infant; Infant, Newborn; Infant, Premature, Disea

1979
Candida-septicemia with chorioretinitis, osteomyelitis and arthritis treated with systemic miconazole and intraarticular amphotericin B.
    Mykosen, 1977, Volume: 20, Issue:7

    Topics: Administration, Oral; Amphotericin B; Arthritis, Infectious; Candidiasis; Chorioretinitis; Humans; I

1977
[Fungal infections after renal transplantation (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Oct-10, Volume: 100, Issue:41

    Topics: Adult; Amphotericin B; Candidiasis; Candidiasis, Oral; Candidiasis, Vulvovaginal; Child; Cholestasis

1975
[Countermeasure for infections with granulocytopenia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Nov-10, Volume: 81, Issue:11

    Topics: Agranulocytosis; Aminoglycosides; Anti-Bacterial Agents; Candidiasis; Cephalosporins; Drug Therapy,

1992
[Diagnosis and management of infections complicated with hematological diseases].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Sep-10, Volume: 80, Issue:9

    Topics: Aminoglycosides; Anti-Bacterial Agents; Granulocyte Colony-Stimulating Factor; Hematologic Diseases;

1991
[A case of sepsis and meningitis due to capsule-deficient Cryptococcus neoformans with SIADH].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1989, Volume: 63, Issue:10

    Topics: Aged; Aged, 80 and over; Cryptococcosis; Cryptococcus neoformans; Drug Resistance, Microbial; Female

1989
[A case of septicemia caused by Trichosporon beigelii (cutaneum) in a patient with myelodysplastic syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1989, Volume: 78, Issue:7

    Topics: Amphotericin B; Female; Humans; Miconazole; Middle Aged; Mycoses; Myelodysplastic Syndromes; Sepsis;

1989
Congenital cutaneous candidiasis and septicaemia treated with miconazole.
    Irish medical journal, 1985, Volume: 78, Issue:8

    Topics: Candidiasis, Cutaneous; Humans; Infant, Newborn; Male; Miconazole; Sepsis

1985