flutamide and Sepsis
flutamide has been researched along with Sepsis in 2 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether treatment with an androgen receptor blocker (eg, flutamide) after trauma-hemorrhage and sepsis has any salutary effects on cell-mediated immunity and on the survival of male animals under those conditions." | 3.69 | Testosterone receptor blockade after hemorrhage in males. Restoration of the depressed immune functions and improved survival following subsequent sepsis. ( Angele, MK; Ayala, A; Chaudry, IH; Cioffi, WG; Wichmann, MW, 1997) |
| "The clinical course after multiple trauma depends on the balance or imbalance of the pro- and anti-inflammatory immune response." | 2.47 | Immunomodulation in polytrauma and polymicrobial sepsis - where do we stand? ( Andruszkow, H; Frink, M; Hildebrand, F; Krettek, C; Mommsen, P; Neunaber, C; Zeckey, C, 2011) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Neunaber, C | 1 |
| Zeckey, C | 1 |
| Andruszkow, H | 1 |
| Frink, M | 1 |
| Mommsen, P | 1 |
| Krettek, C | 1 |
| Hildebrand, F | 1 |
| Angele, MK | 1 |
| Wichmann, MW | 1 |
| Ayala, A | 1 |
| Cioffi, WG | 1 |
| Chaudry, IH | 1 |
Reviews
1 review available for flutamide and Sepsis
| Article | Year |
|---|---|
Immunomodulation in polytrauma and polymicrobial sepsis - where do we stand?
Topics: Androstenediol; Animals; Dehydroepiandrosterone; Finasteride; Flutamide; Humans; Immunomodulation; L | 2011 |
Other Studies
1 other study available for flutamide and Sepsis
| Article | Year |
|---|---|
Testosterone receptor blockade after hemorrhage in males. Restoration of the depressed immune functions and improved survival following subsequent sepsis.
Topics: Androgen Antagonists; Animals; Flutamide; Hemorrhage; Immunity, Cellular; Interleukins; Male; Mice; | 1997 |