3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Sepsis in 2 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lien, JC | 1 |
| Lee, FY | 1 |
| Huang, LJ | 1 |
| Pan, SL | 1 |
| Guh, JH | 1 |
| Teng, CM | 1 |
| Kuo, SC | 1 |
| Sun, HD | 1 |
| Liu, YJ | 1 |
| Chen, J | 1 |
| Chen, MY | 1 |
| Ouyang, B | 1 |
| Guan, XD | 1 |
2 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Sepsis
| Article | Year |
|---|---|
1-Benzyl-3-(5'-hydroxymethyl-2'-furyl)indazole (YC-1) derivatives as novel inhibitors against sodium nitroprusside-induced apoptosis.
Topics: Administration, Oral; Animals; Apoptosis; Cells, Cultured; Enzyme Activators; Indazoles; Mice; Muscl | 2002 |
The pivotal role of HIF-1α in lung inflammatory injury induced by septic mesenteric lymph.
Topics: A549 Cells; Animals; Cell Survival; Cytokines; Endothelial Cells; Gene Silencing; Humans; Hypoxia-In | 2017 |