sevoflurane has been researched along with Sepsis in 16 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The inhalative anesthetic sevoflurane has been shown to elicit protective effects in various inflammatory studies, but its role in peritonitis-induced sepsis remains elusive." | 8.02 | Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling. ( Fabian, F; Fecher, D; Fuhr, A; Gamper-Tsigaras, J; Konrad, FM; Ngamsri, KC; Reutershan, J; Steinke, M; Straub, A; Walles, H, 2021) |
| "Objective We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis." | 7.88 | Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis. ( Bagriacik, EU; Bedirli, A; Bedirli, N; Cavunt Bayraktar, A; Kavutçu, M; Ozkose, Z; Yilmaz, G, 2018) |
| "We have shown that systemic attenuation of inflammation by the volatile anaesthetic sevoflurane did not translate into attenuated neuro-inflammation in this LPS-induced inflammation model." | 7.85 | Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study. ( Baumann, L; Beck-Schimmer, B; Booy, C; Eugster, P; Hasler, M; Restin, T; Schläpfer, M, 2017) |
| "To observe the effects of preconditioning with different concentrations of sevoflurane on cariomyocyte apoptosis and myocardial inflammation in rats with sepsis and explore the possible mechanism of sevoflurane for myocardial protection." | 7.80 | [Effects of sevoflurane preconditioning on cardiomyocyte apoptosis and myocardial inflammation in rats with sepsis]. ( Chen, W; Lai, J; Lin, P; Wang, H; Zhang, L, 2014) |
| "Sevoflurane is an anesthetic agent which also participates in protective mechanisms in sepsis, likely due to anti-inflammatory properties." | 7.79 | Effects of sevoflurane postconditioning on cell death, inflammation and TLR expression in human endothelial cells exposed to LPS. ( Álvarez, J; Baluja, A; Brea, D; Rodríguez, A; Rodríguez, J; Rodríguez-González, R; Taboada, M; Veiras Del Río, S, 2013) |
| "It is unknown how ketamine anesthesia immunologically affects the outcome of patients with postoperative septicemia." | 7.76 | The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia. ( Habu, Y; Kazama, T; Kinoshita, M; Ogura, T; Seki, S; Shono, S; Takahashi, T, 2010) |
| " Sevoflurane combined with oxygen is widely applied in the clinic, and our previous study indicated that this regimen significantly reduced sepsis-induced inflammatory responses and that inhibition of NF-κB pathway activation may contribute to this protection effect." | 5.56 | A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis. ( Hou, L; Hu, Y; Luo, D; Luo, Z; Ma, H; Zhang, E; Zhao, X, 2020) |
| "Sevoflurane was used as the sole anaesthetic agent." | 5.31 | Influence of sepsis on sevoflurane minimum alveolar concentration in a porcine model. ( Allaouchiche, B; Chassard, D; Debon, R; Duflo, F; Tournadre, JP, 2001) |
| "Sevoflurane, a widely used inhalation anesthetic, has been shown to be cardioprotective in individuals with sepsis and myocardial dysfunction." | 4.12 | Molecular Mechanism of Sevoflurane Preconditioning Based on Whole-transcriptome Sequencing of Lipopolysaccharide-induced Cardiac Dysfunction in Mice. ( Li, H; Li, J; Li, S; Li, Y; Xie, J, 2022) |
| "The anesthetic sevoflurane (SEV) has been shown to protect against organ's injury during sepsis." | 4.12 | Sevoflurane ameliorates LPS-induced inflammatory injury of HK-2 cells through Sirtuin1/NF-κB pathway. ( Miaomiao, Y; Peipei, W; Ping, W; Shuo, W, 2022) |
| " The inhalative anesthetic sevoflurane has been shown to elicit protective effects in various inflammatory studies, but its role in peritonitis-induced sepsis remains elusive." | 4.02 | Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling. ( Fabian, F; Fecher, D; Fuhr, A; Gamper-Tsigaras, J; Konrad, FM; Ngamsri, KC; Reutershan, J; Steinke, M; Straub, A; Walles, H, 2021) |
| "Objective We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis." | 3.88 | Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis. ( Bagriacik, EU; Bedirli, A; Bedirli, N; Cavunt Bayraktar, A; Kavutçu, M; Ozkose, Z; Yilmaz, G, 2018) |
| "We have shown that systemic attenuation of inflammation by the volatile anaesthetic sevoflurane did not translate into attenuated neuro-inflammation in this LPS-induced inflammation model." | 3.85 | Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study. ( Baumann, L; Beck-Schimmer, B; Booy, C; Eugster, P; Hasler, M; Restin, T; Schläpfer, M, 2017) |
| "To observe the effects of preconditioning with different concentrations of sevoflurane on cariomyocyte apoptosis and myocardial inflammation in rats with sepsis and explore the possible mechanism of sevoflurane for myocardial protection." | 3.80 | [Effects of sevoflurane preconditioning on cardiomyocyte apoptosis and myocardial inflammation in rats with sepsis]. ( Chen, W; Lai, J; Lin, P; Wang, H; Zhang, L, 2014) |
| "Sevoflurane is an anesthetic agent which also participates in protective mechanisms in sepsis, likely due to anti-inflammatory properties." | 3.79 | Effects of sevoflurane postconditioning on cell death, inflammation and TLR expression in human endothelial cells exposed to LPS. ( Álvarez, J; Baluja, A; Brea, D; Rodríguez, A; Rodríguez, J; Rodríguez-González, R; Taboada, M; Veiras Del Río, S, 2013) |
| "Mice (N = 12 per treatment group) were exposed to anesthetic concentrations of desflurane, isoflurane, and sevoflurane either during induction of sepsis or when the mice showed pronounced symptoms of inflammation." | 3.79 | Volatile anesthetics improve survival after cecal ligation and puncture. ( Beck-Schimmer, B; Castellon, M; Hasler, M; Herrmann, IK; Hu, G; Minshall, RD; Schwartz, DE; Urner, M, 2013) |
| "This study aimed to evaluate the differential protective effects of isoflurane or sevoflurane on lung inflammation in a rat model of cecal ligation and puncture (CLP) induced sepsis." | 3.78 | Volatile anesthetic preconditioning attenuated sepsis induced lung inflammation. ( Akkaya, T; Alper, M; Bedirli, A; Bedirli, N; Demirtas, CY; Pasaoglu, H; Salman, B, 2012) |
| "It is unknown how ketamine anesthesia immunologically affects the outcome of patients with postoperative septicemia." | 3.76 | The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia. ( Habu, Y; Kazama, T; Kinoshita, M; Ogura, T; Seki, S; Shono, S; Takahashi, T, 2010) |
| "The current study demonstrates that pre-treatment with sevoflurane minimizes myocardial dysfunction and the incidence of reperfusion arrhythmia after brief ischaemic insults in septic hearts." | 3.71 | Sevoflurane preconditions stunned myocardium in septic but not healthy isolated rat hearts. ( Ai, K; Innami, Y; Kosugi, S; Kotake, Y; Morisaki, H; Morita, Y; Satoh, T; Serita, R; Takeda, J, 2002) |
| " Sevoflurane combined with oxygen is widely applied in the clinic, and our previous study indicated that this regimen significantly reduced sepsis-induced inflammatory responses and that inhibition of NF-κB pathway activation may contribute to this protection effect." | 1.56 | A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis. ( Hou, L; Hu, Y; Luo, D; Luo, Z; Ma, H; Zhang, E; Zhao, X, 2020) |
| "Myocardial dysfunction accompanied by severe sepsis could significantly increase the mortality rate of septic patients." | 1.51 | Sevoflurane Preconditioning Prevents Septic Myocardial Dysfunction in Lipopolysaccharide-Challenged Mice. ( Chen, Y; Li, H; Li, J; Li, Y; Liu, P; Qi, R; Wang, Y, 2019) |
| "Sevoflurane was used as the sole anaesthetic agent." | 1.31 | Influence of sepsis on sevoflurane minimum alveolar concentration in a porcine model. ( Allaouchiche, B; Chassard, D; Debon, R; Duflo, F; Tournadre, JP, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 5 (31.25) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, J | 1 |
| Li, H | 2 |
| Li, S | 1 |
| Li, J | 2 |
| Li, Y | 2 |
| Peipei, W | 1 |
| Ping, W | 1 |
| Miaomiao, Y | 1 |
| Shuo, W | 1 |
| Liu, P | 1 |
| Wang, Y | 1 |
| Chen, Y | 1 |
| Qi, R | 1 |
| Zhang, E | 1 |
| Zhao, X | 1 |
| Ma, H | 1 |
| Luo, D | 1 |
| Hu, Y | 1 |
| Hou, L | 1 |
| Luo, Z | 1 |
| Chen, H | 1 |
| Peng, Y | 1 |
| Wang, L | 1 |
| Wang, X | 1 |
| Ngamsri, KC | 1 |
| Fabian, F | 1 |
| Fuhr, A | 1 |
| Gamper-Tsigaras, J | 1 |
| Straub, A | 1 |
| Fecher, D | 1 |
| Steinke, M | 1 |
| Walles, H | 1 |
| Reutershan, J | 1 |
| Konrad, FM | 1 |
| Beck-Schimmer, B | 2 |
| Baumann, L | 1 |
| Restin, T | 1 |
| Eugster, P | 1 |
| Hasler, M | 2 |
| Booy, C | 1 |
| Schläpfer, M | 1 |
| Bedirli, N | 2 |
| Bagriacik, EU | 1 |
| Yilmaz, G | 1 |
| Ozkose, Z | 1 |
| Kavutçu, M | 1 |
| Cavunt Bayraktar, A | 1 |
| Bedirli, A | 2 |
| Rodríguez-González, R | 1 |
| Baluja, A | 1 |
| Veiras Del Río, S | 1 |
| Rodríguez, A | 1 |
| Rodríguez, J | 1 |
| Taboada, M | 1 |
| Brea, D | 1 |
| Álvarez, J | 1 |
| Herrmann, IK | 1 |
| Castellon, M | 1 |
| Schwartz, DE | 1 |
| Urner, M | 1 |
| Hu, G | 1 |
| Minshall, RD | 1 |
| Lai, J | 1 |
| Zhang, L | 1 |
| Wang, H | 1 |
| Lin, P | 1 |
| Chen, W | 1 |
| Chen, P | 1 |
| Sinha, A | 1 |
| Takahashi, T | 1 |
| Kinoshita, M | 1 |
| Shono, S | 1 |
| Habu, Y | 1 |
| Ogura, T | 1 |
| Seki, S | 1 |
| Kazama, T | 1 |
| Demirtas, CY | 1 |
| Akkaya, T | 1 |
| Salman, B | 1 |
| Alper, M | 1 |
| Pasaoglu, H | 1 |
| Serita, R | 1 |
| Morisaki, H | 1 |
| Ai, K | 1 |
| Morita, Y | 1 |
| Innami, Y | 1 |
| Satoh, T | 1 |
| Kosugi, S | 1 |
| Kotake, Y | 1 |
| Takeda, J | 1 |
| Allaouchiche, B | 1 |
| Duflo, F | 1 |
| Tournadre, JP | 1 |
| Debon, R | 1 |
| Chassard, D | 1 |
16 other studies available for sevoflurane and Sepsis
| Article | Year |
|---|---|
Molecular Mechanism of Sevoflurane Preconditioning Based on Whole-transcriptome Sequencing of Lipopolysaccharide-induced Cardiac Dysfunction in Mice.
Topics: Animals; Heart Diseases; Lipopolysaccharides; Mice; MicroRNAs; Mitogen-Activated Protein Kinases; Ne | 2022 |
Sevoflurane ameliorates LPS-induced inflammatory injury of HK-2 cells through Sirtuin1/NF-κB pathway.
Topics: Acute Kidney Injury; Epithelial Cells; Humans; Inflammation; Lipopolysaccharides; NF-kappa B; Sepsis | 2022 |
Sevoflurane Preconditioning Prevents Septic Myocardial Dysfunction in Lipopolysaccharide-Challenged Mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Drug Administrat | 2019 |
A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage F | 2020 |
Sevoflurane attenuates cognitive dysfunction and NLRP3-dependent caspase-1/11-GSDMD pathway-mediated pyroptosis in the hippocampus
Topics: Adaptor Proteins, Vesicular Transport; Animals; Caspase 1; Cognitive Dysfunction; Cytokines; Hippoca | 2022 |
Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Hypoxia-Inducible Factor 1; Male; Mice; Mi | 2021 |
Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Inflammation; Inflammation Mediators; Li | 2017 |
Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis.
Topics: Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Apoptosis; bcl-2-Associated X Protein; Brai | 2018 |
Effects of sevoflurane postconditioning on cell death, inflammation and TLR expression in human endothelial cells exposed to LPS.
Topics: Cell Death; Cell Survival; Culture Media; Escherichia coli; Gene Expression Regulation; Human Umbili | 2013 |
Volatile anesthetics improve survival after cecal ligation and puncture.
Topics: Anesthetics, Inhalation; Animals; Cecum; Desflurane; Disease Models, Animal; Inflammation; Isofluran | 2013 |
[Effects of sevoflurane preconditioning on cardiomyocyte apoptosis and myocardial inflammation in rats with sepsis].
Topics: Animals; Apoptosis; Male; Methyl Ethers; Myocarditis; Myocardium; Myocytes, Cardiac; Rats; Rats, Spr | 2014 |
Anaesthetic management of a parturient with factor VII deficiency and sepsis.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Cesarean Section; Factor VII Deficiency; Female | 2015 |
The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia.
Topics: Anesthesia; Animals; Cytokines; Escherichia coli; Escherichia coli Infections; Ketamine; Laparotomy; | 2010 |
Volatile anesthetic preconditioning attenuated sepsis induced lung inflammation.
Topics: Anesthetics, Inhalation; Animals; Cecum; Disease Models, Animal; Intercellular Adhesion Molecule-1; | 2012 |
Sevoflurane preconditions stunned myocardium in septic but not healthy isolated rat hearts.
Topics: Anesthetics, Inhalation; Animals; Arrhythmias, Cardiac; Cardiac Output; Heart; Ischemic Precondition | 2002 |
Influence of sepsis on sevoflurane minimum alveolar concentration in a porcine model.
Topics: Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Ketamine; Methyl Ethers; Mod | 2001 |